Clostridium difficile infection rates and spectrum of disease among peripartum women at one hospital from 2003 to 2007 with molecular typing analysis of recovered Clostridium difficile isolates

American Journal of Infection Control

Volumn 39, Issue 3, 2011, Pages 206-211

  Venugopal, Anilrudh A ^a   Gerding, Dale N ^a,b   Johnson, Stuart ^a,b,c  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b HINES VA HOSPITAL   (United States)

^c LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Clostridium difficile; molecular typing; pregnancy

Indexed keywords

CLINDAMYCIN; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; METRONIDAZOLE; VANCOMYCIN;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; ASPIRATION PNEUMONIA; BACTERIAL STRAIN; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CESAREAN SECTION; CLINICAL FEATURE; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FECES ANALYSIS; FECES CULTURE; FEMALE; GESTATIONAL AGE; HEALTH CARE FACILITY; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MATERNITY WARD; MEDICAL RECORD REVIEW; MOLECULAR TYPING; MORBIDITY; REPEATED DRUG DOSE; RESTRICTION MAPPING; RETROSPECTIVE STUDY; TREATMENT DURATION; VAGINAL DELIVERY;

ADULT; BACTERIAL TYPING TECHNIQUES; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; CROSS INFECTION; FECES; FEMALE; GENOTYPE; HOSPITALS; HUMANS; ILLINOIS; MOLECULAR EPIDEMIOLOGY; MOLECULAR TYPING; PERIPARTUM PERIOD; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; RETROSPECTIVE STUDIES; RISK FACTORS; YOUNG ADULT;

EID: 79953659465     PISSN: 01966553     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajic.2010.06.021     Document Type: Article

References (26)

1. McDonald CL, Killgore GE, Thompson A, Owens RC Jr, Kazakova SV, Sambol SP, et al. An epidemic, toxin gene-variant strain of Clostridium Difficile. N Engl J Med 2005;353:2433-41. (Pubitemid 41770164)
2. Loo VG, Poirier L, Miller MA, Oughton M, Libman MD, Michaud S, et al. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med 2005;353:2442-9. (Pubitemid 41770165)
3. Warny M, Pepin J, Fang A, Killgore G, Thompson A, Brazier J, et al. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet 2005;366:1079-84. (Pubitemid 41338761)
4. McDonald LC, Owings M, Jernigan DB. Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003. Emerg Infect Dis 2006;12:409-15.
5. Johnson S, Gerding DN. Clostridium difficile-associated diarrhea. Clin Infect Dis 1998;26:1027-36.
6. McNeeley SG Jr, Anderson GD, Sibai BM. Clostridium difficile colitis associated with single-dose cefazolin prophylaxis. Obstet Gynecol 1985;66:737-8. (Pubitemid 16216171)
7. Arsura EL, Fazio RA, Wickremesinghe PC. Pseudomembranous colitis following prophylactic antibiotic use in primary cesarean section. Am J Obstet Gynecol 1985;151:87-9. (Pubitemid 15236322)
8. Centers for Disease Control and Prevention (CDC). Severe Clostridium difficile-associated disease in populations previously at low risk: four states, 2005. MMWR Morb Mortal Wkly Rep 2005;54:1201-5.
9. Garey KW, Jiang ZD, Yadav Y, Mullins B, Wong K, Dupont HL. Peripartum Clostridium difficile infection: cases series and review of the literature. Am J Obstet Gynecol 2008;199:332-7.
10. Rouphael NG, O'Donnell JA, Bhatnagar J, Lewis F, Polgreen PM, Beekmann S, et al. Clostridium difficile-associated diarrhea: an emerging threat to pregnant women. Am J Obstet Gynecol 2008;198:635.e1-e6.
11. Clabots CR, Johnson S, Bettin KM, Mathie PA, Mulligan ME, Schaberg DR, et al. Development of a rapid and efficient restriction endonuclease analysis typing system for Clostridium difficile and correlation with other typing systems. J Clin Microbiol 1993;31:1870-5. (Pubitemid 23182592)
12. James AH, Katz VL, Dotters DJ, Rogers RC. Clostridium difficile infection in obstetric and gynecologic patients. South Med J 1997;90:889-92. (Pubitemid 27396508)
13. Clark KH, Jernigan TW, Haley T. Antibiotic-associated Pseudomembranous colitis with toxic megacolon after cesarean section. J Tenn Med Assoc 1993;86:57-8.
14. Alef K. Clostridium difficile-associated disease: implications for midwifery practice. J Nurse-Midwifery 1999;44:19-29.
15. Arora V, Luckas MJM. Pseudomembranous colitis, a complication of erythromycin and preterm prelabour rupture of membranes. BJOG 2006;113:489-90.
16. Ghai S, Ghai V, Sunderji S. Fulminant postcesarean Clostridium difficile Pseudomembranous colitis. Obstet Gynecol 2007;109:541-3. (Pubitemid 46146854)
17. Milstone EB, McDonald AJ, Scholhamer CF. Pseudomembranous colitis after topical application of clindamycin. Arch Dermatol 1981;117:154-5. (Pubitemid 11153914)
18. Trexler MF, Fraser TG, Jones MP. Fulminant Pseudomembranous colitis caused by clindamycin phosphate vaginal cream. Am J Gastroenterol 1997;92:2112-3. (Pubitemid 27476262)
19. Vikenes K, Lund-Tønnesen S, Schreiner A. Clostridium difficile-associated diarrhea after short-term vaginal administration of clindamycin. Am J Gastroenterol 1999;94:1969-70. (Pubitemid 29315922)
20. Dubberke ER, Gerding DN, Classen D, Arias KM, Podgorny K, Anderson DJ, et al. Strategies to prevent Clostridium difficile infection in acute care hospitals. Infect Control Hosp Epidemiol 2008;29:S81-92.
21. McDonald LC, Coignard B, Dubberke E, Song X, Horan T, Kutty PK, and the Ad Hoc Clostridium difficile Surveillance Working Group. Recommendations for surveillance of Clostridium difficile-associated disease. Infect Control Hosp Epidemiol 2007;28:140-5.
22. Kuijper EJ, Coignard B, Tüll P. ESCMID Study Group for Clostridium difficile; EU Member States; European Centre for Disease Prevention and Control. Emergence of Clostridium difficile-associated disease in North America and Europe. Clin Microbiol Infect 2006;(Suppl 6):2-18.
23. Pierce PF Jr, Wilson R, Silva J Jr, Garagusi VF, Rifkin GD, Fekety R, et al. Antibiotic-associated Pseudomembranous colitis: an epidemiologic investigation of a cluster of cases. J Infect Dis 1982;145:269-74. (Pubitemid 12177647)
24. Siddiqui F, Vedantam G, Gerding DN, Johnson S. The tcdC gene of C difficile variants including the epidemic BI strain contains stop codons and deletions. The 5th International Meeting on the Molecular Biology and Pathogenesis of Clostridia. Nottingham, UK. June 21-25, 2006.
25. Rupnik M, Avesani V, Janc M, von Eichel-Streiber C, Delmee M. A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates. J Clin Microbiol 1998;36:2240-7. (Pubitemid 28324074)
26. Kuntz JL, Yang M, Cavanaugh J, Saftlas AF, Polgreen PM. Trends in Clostridium difficile infection among peripartum women. Infect Control Hosp Epidemiol 2010;31:532-4.