Increased Rho-kinase expression and activity and pulmonary endothelial dysfunction in smokers with normal lung function

European Respiratory Journal

Volumn 37, Issue 2, 2011, Pages 349-355

  Duong Quy, S ^a   Dao, P ^a   Hua Huy, T ^a   Guilluy, C ^b   Pacaud, P ^b   Dinh Xuan, A T ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b UNIVERSITÉ DE NANTES   (France)

Author keywords

Cyclic guanosine monophosphate; Endothelial dysfunction; Endothelial nitric oxide synthase; Rho kinases; RhoA; Tobacco smoke

Indexed keywords

ACETYLCHOLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MYOSIN PHOSPHATASE SUBUNIT 1; NITRIC OXIDE; PHOSPHATASE; RHO KINASE; RHO KINASE 1; RHO KINASE 2; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTERY DILATATION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LUNG ARTERY; LUNG CARCINOMA; LUNG FUNCTION; LUNG LOBECTOMY; LUNG PARENCHYMA; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY VASCULAR DISEASE; SIGNAL TRANSDUCTION; SMOKING;

ACETYLCHOLINE; AGED; CARCINOMA, BRONCHOGENIC; ENDOTHELIUM, VASCULAR; HUMANS; LUNG; LUNG NEOPLASMS; MALE; MIDDLE AGED; MYOSIN-LIGHT-CHAIN PHOSPHATASE; NITRIC OXIDE SYNTHASE TYPE III; PULMONARY ARTERY; RESPIRATORY FUNCTION TESTS; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SMOKING; VASOCONSTRICTION;

EID: 79953654324     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00056610     Document Type: Article

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