Transmission electron microscopy with a liquid flow cell

Journal of Microscopy

Volumn 242, Issue 2, 2011, Pages 117-123

  Klein, K L ^a   Anderson, I M ^a   De Jonge, N ^b  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chromatic aberration; in situ; Liquid; Nanoparticles; Spatial resolution; STEM; TEM

Indexed keywords

ABERRATIONS; CELLS; CYTOLOGY; ELECTRONS; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; IMAGE RESOLUTION; INELASTIC SCATTERING; SCANNING ELECTRON MICROSCOPY;

CHROMATIC ABERRATION; CONVENTIONAL TRANSMISSION ELECTRON MICROSCOPIES; IN SITU; LIQUID ENVIRONMENT; LIQUID FLOW CELLS; MICROSCOPIC STRUCTURES; MICROSCOPY IMAGING; NANOMETRES; SPATIAL RESOLUTION; STEM;

NANOPARTICLES;

NANOPARTICLE; WATER;

ARTICLE; CHROMOSOME ABERRATION; ELECTRON BEAM; ELECTRON RADIATION; IMAGING; LIQUID; OPTICAL RESOLUTION; PARTICLE SIZE; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

EID: 79953330529     PISSN: 00222720     EISSN: 13652818     Source Type: Journal    
DOI: 10.1111/j.1365-2818.2010.03484.x     Document Type: Article

References (17)

1. Cowley, J.M. (1969) Image contrast in a transmission scanning electron microscope. Appl. Phys. Lett. 15, 58.
2. Danilatos, G.D. & Robinson, V.N.E. (1979) Principles of scanning electron microscopy at high specimen pressures. Scanning 18, 75-78.
3. Daulton, T.L., Little, B.J., Lowe, K. & Jones-Meehan, J. (2001) In situ environmental cell-transmission electron microscopy study of microbial reduction of chromium(VI) using electron energy loss spectroscopy. Microsc. Microanal. 7, 470-485.
4. de Jonge, N., Peckys, D.B., Kremers, G.J. & Piston, D.W. (2009) Electron microscopy of whole cells in liquid with nanometer resolution. Proc. Natl. Acad. Sci. USA 106, 2159-2164.
5. de Jonge, N., Poirier-Demers, N., Peckys, D.B. & Drouin, D. (2010) Nanometer-resolution electron microscopy through micrometers-thick water layers. Ultramicroscopy 110, 1114-1119.
6. Liu, K.L., Wu, C.C., Huang, Y.J., Peng, H.L., Chang, H.Y., Chang, P., Hsu, L. & Yew, T.R. (2008) Novel microchip for in situ TEM imaging of living organisms and bio-reactions in aqueous conditions. Lab Chip 8, 1915-1921.
7. Marton, L. (1935) Electron microscopy of biological objects. II. Bulletins de l'Academie Royal de Belgique, Class des Sciences 21, 553-564.
8. Nishiyama, H., Suga, M., Ogura, T., Maruyama, Y., Koizumi, M., Mio, K., Kitamura, S. & Sato, C. (2010) Atmospheric scanning electron microscope observes cells and tissues in open medium through silicon nitride film. J. Struct. Biol. 169, 438-449.
9. NIST RM 8011. (2007) Reference Material 8011: Gold Nanoparticles, Nominal 10 nm Diameter. Report issued December 13, 2007. National Institute of Standards and Technology, Gaithersburg, MD, USA
10. Parsons, D.F. (1974) Structure of wet specimens in electron-microscopy. Science 186, 407-414.
11. Reimer, L. (1985) Scanning Electron Microscopy: Physics of Image Formation and Microanalysis, 1st edn. Springer, Heidelberg
12. Reimer, L. & Kohl, H. (2008) Transmission Electron Microscopy, 5th edn. Springer, New York
13. Ring, E.A. & de Jonge, N. (2010) Microfluidic system for transmission electron microscopy. Microsc. Microanal. 16, 622-629.
14. Thiberge, S., Nechushtan, A., Sprinzak, D., et al (2004) Scanning electron microscopy of cells and tissues under fully hydrated conditions. Proc. Natl. Acad. Sci. USA 101, 3346-3351.
15. Williamson, M.J., Tromp, R.M., Vereecken, P.M., Hull, R. & Ross, F.M. (2003) Dynamic microscopy of nanoscale cluster growth at the solid-liquid interface. Nat. Mater. 2, 532-536.
16. Zheng, H.M., Claridge, S.A., Minor, A.M., Alivisatos, A.P. & Dahmen, U. (2009a) Nanocrystal diffusion in a liquid thin film observed by in situ transmission electron microscopy. Nano Lett. 9, 2460-2465.
17. Zheng, H.M., Smith, R.K., Jun, Y.W., Kisielowski, C., Dahmen, U. & Alivisatos, A.P. (2009b) Observation of single colloidal platinum nanocrystal growth trajectories. Science 324, 1309-1312.