Bipolar disorder, cognitive functioning and hypothalamic-pituitary-thyroid axis abstract;Trastorno bipolar, funciones cognitivas y eje hipotalámico- pituitario-tiroideo

Actas Espanolas de Psiquiatria

Volumn 38, Issue 4, 2010, Pages 223-228

  Bonnin, C M ^a   Martinez Aran, A ^a   Sanchez Moreno, J ^a,b   Torrent, C ^a   Franco, C ^a   Pacchiarotti, I ^a   Vieta, Eduard ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Bipolar disorder; Hypothalamic pituitary thyroid axis; Neuropsychological functions

Indexed keywords

BIPOLAR DISORDER; COGNITIVE DEFECT; HUMAN; HYPOTHALAMUS HYPOPHYSIS SYSTEM; PATHOPHYSIOLOGY; REVIEW; THYROID GLAND;

BIPOLAR DISORDER; COGNITION DISORDERS; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; THYROID GLAND;

EID: 79953324187     PISSN: 11399287     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (76)

1. Hirschfetd RM, Calabrese JR, Weissman MM, et al. Screening for bipolar disorder in the community. J Clin Psychiatry 2003;64:53-9 (Pubitemid 36182230)
2. Merikangas KR, Akiskal HS, Angst J, et al. Lifetime and 12-month prevalence of bipolar spectrum disorder in the national comorbidity survey replication. Arch Gen Psychiatry 2007;64:543-52 (Pubitemid 46718287)
3. Angst J. [Epidemiology of the bipolar spectrum]. Encephale 1995;21 Spec No 6:37-42
4. Vieta E, Gasto C, Martinez de Osaba MJ, et al. Prediction of depressive relapse in remitted bipolar patients using corticotrophin-releasing hormone challenge test. Acta Psychiatr Scand 1997;95:205-11 (Pubitemid 27140291)
5. Holsboer F. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 2000;23:477-501
6. Daban C, Vieta E, Mackin P, et al. Hypothalamic-pituitaryadrenal axis and bipolar disorder. Psychiatr Clin North Am 2005;28:469-80
7. Zubieta JK, Huguelet P, O'Neil RL, et al. Cognitive function in euthymic bipolar I disorder. Psychiatry Res 2001;102:9-20 (Pubitemid 32463920)
8. Martinez-Aran A, Vieta E, Colom F, et al. Cognitive impairment in euthymic bipolar patients: implications for clinical and functional outcome. Bipolar Disord 2004;6:224-32 (Pubitemid 38702298)
9. Martinez-Aran A, Vieta E, Reinares M, et al. Cognitive function across manic or hypomanic, depressed, and euthymic states in bipolar disorder. Am J Psychiatry 2004;161:262-70 (Pubitemid 38419277)
10. Robinson U, Thompson JM, Gallagher P, et al. A meta-analysis of cognitive deficits in euthymic patients with bipolar disorder. J Affect Disord 2006;93:105-15 (Pubitemid 43816055)
11. Martinez-Aran A, Vieta E, Torrent C, et al. Functional outcome in bipolar disorder: the role of clinical and cognitive factors. Bipolar Disord 2007;9:103-13 (Pubitemid 46671678)
12. Torrent C, Martinez-Aran A, Amann B, et al. Cognitive impairment in schizoaffective disorder: a comparison with nonpsychotic bipolar and healthy subjects. Acta Psychiatr Scand 2007;116:453-60 (Pubitemid 350086147)
13. Denicoff KD, Ali SO, Mirsky AF, et al. Relationship between prior course of illness and neuropsychological functioning in patients with bipolar disorder. J Affect Disord 1999;56:67-73
14. Balanza-Martinez V, Rubio C, Selva-Vera G, et al. Neurocognitive endophenotypes (Endophenocognitypes) from studies of relatives of bipolar disorder subjects: A systematic review. Neurosci Biobehav Rev 2008;
15. Arts B, Jabben N, Krabbendam L, et al. Meta-analyses of cognitive functioning in euthymic bipolar patients and their firstdegree relatives. Psychol Med 2008;38:771-85 (Pubitemid 351684591)
16. Martinez-Aran A, Penades R, Vieta E, et al. Executive function in patients with remitted bipolar disorder and schizophrenia and its relationship with functional outcome. Psychother Psychosom 2002;71:39-46
17. Mur M, Portella MJ, Martinez-Aran A, et al. Persistent neuropsychological deficit in euthymic bipolar patients: executive function as a core deficit. J Clin Psychiatry 2007;68:1078-86 (Pubitemid 47340329)
18. Mur M, Portella MJ, Martinez-Aran A, et al. Long-Term Stability of Cognitive Impairment in Bipolar Disorder: A 2-Year Follow-Up Study of Lithium-Treated Euthymic Bipolar Patients. J Clin Psychiatry 2008; e1-e8
19. Kolur US, Reddy YC, John JP, et al. Sustained attention and executive functions in euthymic young people with bipolar disorder. Br J Psychiatry 2006;189:453-8 (Pubitemid 44683179)
20. Daban C, Martinez-Aran A, Torrent C, et al. Specificity of cognitive deficits in bipolar disorder versus schizophrenia. A systematic review. Psychother Psychosom 2006;75:72-84
21. Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003;160:636-45 (Pubitemid 41079594)
22. Ferrier IN, Chowdhury R, Thompson JM, et al. Neurocognitive function in unaffected first-degree relatives of patients with bipolar disorder: a preliminary report. Bipolar Disord 2004;6:319-22 (Pubitemid 39077093)
23. Zalla T, Joyce C, Szoke A, et al. Executive dysfunctions as potential markers of familial vulnerability to bipolar disorder and schizophrenia. Psychiatry Res 2004;121:207-17 (Pubitemid 37522174)
24. Frantom LV, Allen DN, Cross CL Neurocognitive endophenotypes for bipolar disorder. Bipolar Disord 2008;10:387-99 (Pubitemid 351517373)
25. Bora E, Vahip S, Akdeniz F, et al. Executive and verbal working memory dysfunction in first-degree relatives of patients with bipolar disorder. Psychiatry Res 2008;
26. Hartman DE. Neuropsychological toxicology. Identification and assessment of human neurotoxic syndromes. 2nd Edition ed. NY: 1995
27. van Gorp WG, Altshuler L, Theberge DC, et al. Cognitive impairment in euthymic bipolar patients with and without prior alcohol dependence. A preliminary study. Arch Gen Psychiatry 1998;55:41-6 (Pubitemid 28069038)
28. Savitz JB, van der ML, Stein DJ, et al. Neuropsychological task performance in bipolar spectrum illness: genetics, alcohol abuse, medication and childhood trauma. Bipolar Disord 2008;10:479-94 (Pubitemid 351619164)
29. Tabarés-Seisdedos R, Balanzá-Martinez V, Sanchez-Moreno J, Martinez-Aran A, Salazar-Fraile J, Selva-Vera G, Rubio C, Mata I, Gómez-Beneyto M, Vieta E. Neurocognitive and clinical predictors of functional outcome in patients with schizophrenia and bipolar I disorder at one-year follow-up. J Affect Disord. 2008 Aug; 109(3) : 286-99
30. Ferrier IN, Stanton BR, Kelly TP, et al. Neuropsychological function in euthymic patients with bipolar disorder. Br J Psychiatry 1999;175:246-51 (Pubitemid 29406594)
31. Clark L, Iversen SD, Goodwin GM. Sustained attention deficit in bipolar disorder. Br J Psychiatry 2002;180:313-9 (Pubitemid 34407317)
32. Torrent C, Martinez-Aran A, Daban C, et al. Cognitive impairment in bipolar II disorder. Br J Psychiatry 2006;189:254-9 (Pubitemid 44343471)
33. Martinez-Aran A, Torrent C, Tabares-Seisdedos R, et al. Neurocognitive impairment in bipolar patients with and without history of psychosis. J Clin Psychiatry 2008;69:233-9 (Pubitemid 351469266)
34. Glahn DC, Bearden CE, Barguil M, Barrett J, Reichenberg A, Bowden CL, Soares JC, Velligan Dl. The neurocognitive signature of psychotic bipolar disorder Biol Psychiatry. 2007 Oct. 15; 62(8) : 910-6 (Pubitemid 47488219)
35. Goodwin GM, Martinez-Aran A, Glahn DC, et al. Cognitive impairment in bipolar disorder: neurodevelopment or neurodegeneration? An ECNP expert meeting report. Eur Neuropsychopharmacol 2008;18:787-93
36. Cowdry RW, Wehr TA, Zis AP, et al. Thyroid abnormalities associated with rapid-cycling bipolar illness. Arch Gen Psychiatry 1983;40:414-20 (Pubitemid 13118576)
37. Wehr TA, Sack DA, Rosenthal NE, et al. Rapid cycling affective disorder: contributing factors and treatment responses in 51 patients. Am J Psychiatry 1988;145:179-84 (Pubitemid 18058361)
38. Joffe RT, Kutcher S, MacDonald C. Thyroid function and bipolar affective disorder. Psychiatry Res 1988;25:117-21
39. Oomen HA, Schipperijn AJ, Drexhage HA. The prevalence of affective disorder and in particular of a rapid cycling of bipolar disorder in patients with abnormal thyroid function tests. Clin Endocrinol (Oxf) 1996;45:215-23 (Pubitemid 26278316)
40. Lazarus JH. The effects of lithium therapy on thyroid and thyrotropin-releasing hormone. Thyroid 1998;8:909-13 (Pubitemid 28514183)
41. Valle J, Ayuso-Gutierrez JL, Abril A, et al. Evaluation of thyroid function in lithium-naive bipolar patients. Eur Psychiatry 1999;14:341-5
42. Zhang ZJ, Qiang L, Kang WH, et al. Differences in hypothyroidism between lithium-free and-treated patients with bipolar disorders. Life Sci 2006;78:771-6 (Pubitemid 41821135)
43. Bauer MS, Whybrow PC, Winokur A. Rapid cycling bipolar affective disorder. I. Association with grade I hypothyroidism. Arch Gen Psychiatry 1990;47:427-32 (Pubitemid 20161261)
44. Gyulai L, Bauer M, Bauer MS, et al. Thyroid hypofunction in patients with rapid-cycling bipolar disorder after lithium challenge. Biol Psychiatry 2003;53:899-905 (Pubitemid 36556175)
45. Zarate CA, Tohen M, Zarate SB. Thyroid function tests in firstepisode bipolar disorder manic and mixed types. Biol Psychiatry 1997;42:302-4 (Pubitemid 27325821)
46. Chang KD, Keck PE, Jr., Stanton SP, et al. Differences in thyroid function between bipolar manic and mixed states. Biol Psychiatry 1998;43:730-3 (Pubitemid 28259575)
47. Cassidy F, Ahearn EP, Carroll BJ. Thyroid function in mixed and pure manic episodes. Bipolar Disord 2002;4:393-7 (Pubitemid 36041469)
48. Musselman DL, Nemeroff CB. Depression and endocrine disorders: focus on the thyroid and adrenal system. Br J Psychiatry Suppl 1996;123-8 (Pubitemid 26179811)
49. Loosen PT, Prange AJ, Jr. Serum thyrotropin response to thyrotropin-releasing hormone in psychiatric patients: a review. Am J Psychiatry 1982;139:405-16 (Pubitemid 12141031)
50. Larsen JK, Faber J, Christensen EM, et al. Relationship between mood and TSH response to TRH stimulation in bipolar affective disorder. Psychoneuroendocrinology 2004;29:917-24 (Pubitemid 38716117)
51. Gold MS, Pottash AL, Extein I. "Symptomless" autoimmune thyroiditis in depression. Psychiatry Res 1982;6:261-9
52. Nemeroff CB, Simon JS, Haggerty JJ, Jr., et al. Antithyroid antibodies in depressed patients. Am J Psychiatry 1985;142:840-3 (Pubitemid 15037214)
53. Banki CM, Bissette G, Arato M, et al. Elevation of immunoreactive CSFTRH in depressed patients. Am J Psychiatry 1988;145:1526-31 (Pubitemid 19009699)
54. Kirkegaard C, Faber J, Hummer L, et al. Increased levels of TRH in cerebrospinal fluid from patients with endogenous depression. Psychoneuroendocrinology 1979;4:227-35 (Pubitemid 10209953)
55. Cole DP, Thase ME, Mallinger AG, et al. Slower treatment response in bipolar depression predicted by lower pretreatment thyroid function. Am J Psychiatry 2002;159:116-21 (Pubitemid 41070736)
56. Frye MA, Denicoff KD, Bryan AL, et al. Association between lower serum free T4 and greater mood instability and depression in lithiummaintained bipolar patients. Am J Psychiatry 1999;156:1909-14
57. Hatterer JA, Kocsis JH, Stokes PE. Thyroid function in patients maintained on lithium. Psychiatry Res 1988;26:249-57 (Pubitemid 19021043)
58. Rao ML, Ruhrmann S, Retey B, et al. Low plasma thyroid indices of depressed patients are attenuated by antidepressant drugs and influence treatment outcome. Pharmacopsychiatry 1996;29:180-6 (Pubitemid 26315669)
59. Haggerty JJ, Jr., Stern RA, Mason GA, et al. Subclinical hypothyroidism: a modifiable risk factor for depression? Am J Psychiatry 1993;150:508-10 (Pubitemid 23072484)
60. Bernal J, Nunez J. Thyroid hormones and brain development. Eur J Endocrinol 1995;133:390-8
61. Dugbartey AT. Neurocognitive aspects of hypothyroidism. Arch Intern Med 1998;158:1413-8 (Pubitemid 28317756)
62. Haggerty JJ, Jr., Evans DL, Prange AJ, Jr. Organic brain syndrome associated with marginal hypothyroidism. Am J Psychiatry 1986;143:785-6 (Pubitemid 16050858)
63. Nystrom E, Caidahl K, Fager G, et al. A double-blind cross-over 12-month study of L-thyroxine treatment of women with 'subclinical' hypothyroidism. Clin Endocrinol (Oxf) 1988;29:63-75
64. Monzani F, Del GP, Caraccio N, et al. Subclinical hypothyroidism: neurobehavioral features and beneficial effect of L-thyroxine treatment. Clin Investig 1993;71:367-71 (Pubitemid 23142835)
65. Bono G, Fancellu R, Blandini F, et al. Cognitive and affective status in mild hypothyroidism and interactions with L-thyroxine treatment. Acta Neurol Scand 2004;110:59-66 (Pubitemid 38850557)
66. Jorde R, Waterloo K, Storhaug H, et al. Neuropsychological function and symptoms in subjects with subclinical hypothyroidism and the effect of thyroxine treatment. J Clin Endocrinol Metab 2006;91:145-53 (Pubitemid 43069130)
67. Mur M, Portella MJ, Martinez-Aran A, et al. Long-term stability of cognitive impairment in bipolar disorder: a 2-year follow-up study of lithium-treated euthymic bipolar patients. J Clin Psychiatry 2008;69:712-9 (Pubitemid 351838680)
68. Whybrow PC, Prange AJ, Jr. A hypothesis of thyroid-catecholamine-receptor interaction. Its relevance to affective illness. Arch Gen Psychiatry 1981;38:106-13 (Pubitemid 11156719)
69. Bauer M, Whybrow PC. Thyroid hormone, neural tissue and mood modulation. World J Biol Psychiatry 2001;2:59-69
70. Smith JW, Evans AT, Costall B, et al. Thyroid hormones, brain function and cognition: a brief review. Neurosci Biobehav Rev 2002;26:45-60 (Pubitemid 34130533)
71. Prohaska ML, Stern RA, Nevéis CT, et al. Thyroid hormone and lithium related-neuropsychological deficits: a preliminary test of the lithium-thyroid interactive hypothesis. J Int Neuropsychological Soc 1995;134
72. Prohaska ML, Stern RA, Nevéis CT, et al. The relationship between thyroid status and neuropsychology performance in psychiatric outpatients maintained on lithium. Neuropsychiatry Neuropsychol Behav Neurol 1996;9:30-4 (Pubitemid 26025352)
73. Whybrow PC. The therapeutic use of triiodothyronine and high dose thyroxine in psychiatric disorder. Acta Med Austríaca 1994;21:47-52 (Pubitemid 24285080)
74. Bauer M, Berghofer A, Bschor T, et al. Supraphysiological doses of L-thyroxine in the maintenance treatment of prophylaxis-resistant affective disorders. Neuropsychopharmacology 2002;27:620-8
75. Bauer M, London ED, Rasgón N, et al. Supraphysiological doses of levothyroxine alter regional cerebral metabolism and improve mood in bipolar depression. Mol Psychiatry 2005;10:456-69 (Pubitemid 40646434)
76. Stern RA, Nevéis CT, Shelhorse ME, et al. Antidepressant and memory effects of combined thyroid hormone treatment and electroconvulsive therapy: preliminary findings. Biol Psychiatry 1991;30:623-7