Simultaneous determination of liquiritin, hesperidin, and glycyrrhizin by HPLC-photodiode array detection and the anti-inflammatory effect of Pyungwi-san

Archives of Pharmacal Research

Volumn 34, Issue 2, 2011, Pages 203-210

  Seo, Chang Seob ^a   Lee, Jin Ah ^a   Jung, Dayoung ^a   Lee, Ho Young ^a   Lee, Jun Kyoung ^a   Ha, Hyekyung ^a   Lee, Mee Young ^a   Shin, Hyeun Kyoo ^a  

^a Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

Glycyrrhizin; Hesperidin; HPLC PDA; Liquiritin; Pyungwi san; Simultaneous determination

Indexed keywords

ACETIC ACID; ACETONITRILE; GLYCYRRHIZIC ACID; HERBACEOUS AGENT; HESPERIDIN; INDOMETACIN; LIPOPOLYSACCHARIDE; LIQUIRITIN; NITRIC OXIDE; PROSTAGLANDIN E2; PYUNGWI-SAN; SOLVENT; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DENSITY GRADIENT; DRUG DETERMINATION; DRUG EFFECT; DRUG SCREENING; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; PAW EDEMA; RAT; REVERSED PHASE LIQUID CHROMATOGRAPHY; TEMPERATURE; TRADITIONAL MEDICINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CALIBRATION; CELL LINE; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DINOPROSTONE; DRUG EVALUATION, PRECLINICAL; FLAVANONES; GLUCOSIDES; GLYCYRRHIZIC ACID; HESPERIDIN; INFLAMMATION; MALE; MEDICINE, KOREAN TRADITIONAL; MICE; MICE, INBRED BALB C; PLANT EXTRACTS; RATS;

EID: 79953317687     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-011-0204-2     Document Type: Article

References (30)

1. Baltina, L. A., Chemical modification of glycyrrhzic acid as a route to new bioactive compounds for medicine. Curr. Med. Chem., 10, 155-171 (2003).
2. Choi, I. Y., Kim, S. J., Jeong, H. J., Park, S. H., Song, Y. S., Lee, J. H., Kang, T. H., Park, J. H., Hwang, G. S., Lee, E. J., Hong, S. H., Kim, H. M., and Um, J. Y., Hesperidin inhibits expression of hypoxia inducible factor-1 alpha and inflammatory cytokine production from mast cells. Mol. Cell. Biochem., 305, 153-161 (2007).
3. Funk, J. L., Frye, J. B., Oyarzo, J. N., and Timmermann, B. N., Comparative effects of two gingerol-containing Zingiber officinale extracts on experimental rheumatoid arthritis. J. Nat. Prod., 72, 403-407 (2009).
4. Galati, E. M., Monforte, M. T., Kirjavainen, S., Forestieri, A. M., Trovato, A., and Tripodo, M. M., Biological effects of hesperidin, a citrus flavonoid. (Note I): anti-inflammatory and analgesic activity. Farmaco, 40, 709-712 (1994).
5. Gambero, A., Becker, T. L., Gurgueira, S. A., Benvengo, Y. H., Ribeiro, M. L., de Mendonca, S., and Pedrazzoli, J. Jr., Acute inflammatory response induced by Helicobacter pylori in the rat air pouch. FEMS Immunol. Med. Microbiol., 38, 193-198 (2003).
6. Harris, S. G., Padilla, J., Koumas, L., Ray, D., and Phipps, R. P., Prostaglandins as modulators of immunity. Trends Immunol., 23, 144-150 (2002).
7. Heo, J., Dongeuibogam. Namsandang, Seoul, pp. 435, (1994).
8. Hong, M. H., Kim, J. H., Bae, H., Lee, N. Y., Shin, Y. C., Kim, S. H., and Ko, S. G., Atractylodes japonica Koidzumi inhibits the production of proinflammatory cytokines through inhibition of the NF-kappaB/IkappaB signal pathway in HMC-1 human mast cells. Arch. Pharm. Res., 33, 843-851 (2010).
9. Jayaprakasam, B., Doddaga, S., Wang, R., Holmes, D., Goldfarb, J., and Li, X. M., Licorice flavonoids inhibit eotaxin-1 secretion by human fetal lung fibroblasts in vitro. J. Agric. Food Chem., 57, 820-825 (2009).
10. Jung, H. W., Yoon, C. H., Park, K. M., Han H. S., and Park, Y. K., Hexane fraction of Zingiberis Rhizoma Crudus extract inhibits the production of nitric oxide and proinflammatory cytokines in LPS-stimulated BV2 microglial cells via the NF-kappaB pathway. Food Chem. Toxicol., 47, 1190-1197 (2009).
11. Kim, K. S., Rhee, H. I., Park, E. K., Jung, K., Jeon, H. J., Kim, J. H., Yoo, H., Han, C. K., Cho, Y. B., Ryu, C. J., Yang, H. I., and Yoo, M. C., Anti-inflammatory effects of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) in animal models. Chin. Med., 2, 3-10 (2008).
12. Kim, N. Y. and Ryu, J. H., Butanolides from Machilus thunbergii and their inhibitory activity on nitric oxide synthesis in activated macrophages. Phytother. Res., 17, 372-375 (2003).
13. Kim, Y. W., Ki, S. H., Lee, J. R., Lee, S. J., Kim, C. W., Kim, S. C., and Kim, S. G., Liquiritigenin, an aglycone of liquiritin in Glycyrrhizae radix, prevents acute liver injuries in rats induced by acetaminophen with or without buthionine sulfoximine. Chem. Biol. Interact., 161, 125-138 (2006).
14. Lee, T. Y., Lee, K. C., Chen, S. Y., and Chang, H. H., 6-Gingerol inhibits ROS and iNOS through the suppression of PKC-alpha and NF-kappaB pathways in lipopolysaccharide-stimulated mouse macrophages. Biochem. Biophys. Res. Commun., 382, 134-139 (2009).
15. Lin, Y. R., Chen, H. H., Ko, C. H., and Chan, M. H., Effects of honokiol and magnolol on acute and inflammatory pain models in mice. Life Sci., 81, 1071-1078 (2007).
16. Lin, Y. R., Chen, H. H., Lin, Y. C., Ko, C. H., and Chan, M. H., Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain. J. Biomed. Sci., 16, 94 (2009).
17. Lundberg, I. E., The role of cytokines, chemokines, and adhesion molecules in the pathogenesis of idiopathic inflammatory myopathies. Curr. Rheumatol. Rep., 2, 216-224 (2000).
18. McCann, S. M., Mastronardi, C., de Laurentiis, A., and Rettori, V., The nitric oxide theory of aging revisited. Ann. N. Y. Acad. Sci., 1057, 64-84 (2005).
19. Menegazzi, M., Di Paola, R., Mazzon, E., Genovese, T., Crisafulli, C., Dal Bosco, M., Zou, Z., Suzuki, H., and Cuzzocrea, S., Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice. Pharmacol. Res., 58, 22-31 (2008).
20. Resch, M., Steigel, A., Chen, Z. L., and Bauer, R., 5-Lipoxygenase and cyclooxygenase-1 inhibitory active compounds from Atractylodes lancea. J. Nat. Prod., 61, 347-350 (1998).
21. Riedlinger, J. E., Tan, P. W., and Lu, W., Ping wei san, a Chinese medicine for gastrointestinal disorders. Ann. Pharmacother., 35, 228-235 (2001).
22. Salvemini, D., Wang, Z. Q., Xyatt, P. S., Bourdon, D. M., Marino, M. H., Manning, P. T., and Currie, M. G., Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br. J. Pharmacol., 118, 829-838 (1996).
23. Schröfelbauer, B., Raffetseder, J., Hauner, M., Wolkerstorfer, A., Ernst, W., and Szolar, O. H., Glycyrrhizin, the main active compound in liquorice, attenuates pro-inflammatory responses by interfering with membrane-dependent receptor signalling. Biochem. J., 421, 473-482 (2009).
24. Walsh, L. J., Mast cells and oral inflammation. Crit. Rev. Oral. Biol. Med., 14, 188-198 (2003).
25. Winter, C. A., Risely, E. A., and Nuss, G. W., Carrageenin-induced edema in hind paw of the rat as an assay for anti-inflammatory drugs. Proc. Soc. Exp. Biol. Med., 111, 544-547 (1962).
26. Yamauchi, Y., Ueda, J., and Ohsawa, K., A Simultaneous determination of various main components in oriental pharmaceutical decoction "heii-san" by ion-pair high-performance liquid chromatography. Yakugaku Zasshi, 116, 776-782 (1996).
27. Yeh, C. C., Kao, S. J., Lin, C. C., Wang, S. D., Liu, C. J., and Kao, S. T., The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro. Life Sci., 80, 1821-1831 (2007).
28. Yoshida, T., Abe, K., Ikeda, T., Matsushita, T., Wake, K., Sato, T., Sato, T., and Inoue, H., Inhibitory effect of glycyrrhizin on lipopolysaccharide and d-galactosamine-induced mouse liver injury. Eur. J. Pharmacol., 576, 136-142 (2007).
29. Yoshikawa, Y., Matsui, H., Kawamoto, N., Umemoto, K., Oku, M., Koizumi, J., Yamao, S., Kuriyama, H., Nakano, N., Hozumi, S., and Fukui, I. H., Effects of glycyrrhizin on immune-mediated cytotoxicity. J. Gastroenterol. Hepatol., 12, 243-248 (1997).
30. Zhang, H., Shen, P., and Cheng, Y., Identification and determination of the major constituents in traditional Chinese medicine Si-Wu-Tang by HPLC coupled with DAD and ESI-MS. J. Pharm. Biomed. Anal., 34, 705-713 (2004).