Behavior of central and peripheral chemoreflexes in heart failure

Arquivos Brasileiros de Cardiologia

Volumn 96, Issue 2, 2011, Pages 161-167

  Guimarães, Guilherme Veiga ^a   Belli, Juliana Fernanda Canhadas ^a   Bacal, Fernando ^a   Bocchi, Edimar Alcides ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Autonomic nervous system; Baroreflex drugs effects; Heart failure therapy

Indexed keywords

ADRENERGIC RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BRAIN NATRIURETIC PEPTIDE; CARBON DIOXIDE; CATECHOLAMINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; NITRIC OXIDE;

ANGIOTENSIN BLOOD LEVEL; AORTA CHEMORECEPTOR; ARTERIAL CARBON DIOXIDE TENSION; ARTERIAL OXYGEN TENSION; CAROTID BODY; CENTRAL CHEMOREFLEX; CHEMORECEPTOR; CHEMORECEPTOR REFLEX; CHEYNE STOKES BREATHING; DAILY LIFE ACTIVITY; DIASTOLIC DYSFUNCTION; DISEASE SEVERITY; GAS DIFFUSION; GLOSSOPHARYNGEAL NERVE; HEART FAILURE; HEART OUTPUT; HEART RATE; HORMONAL REGULATION; HUMAN; HYPERCAPNIA; HYPERVENTILATION; HYPOXEMIA; HYPOXIA; KIDNEY VASCULAR RESISTANCE; LUNG VENTILATION; MEDULLA OBLONGATA; NEGATIVE FEEDBACK; PARASYMPATHETIC TONE; PERIPHERAL CHEMOREFLEX; PRESSORECEPTOR REFLEX; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVIEW; SYMPATHETIC TONE; SYSTOLIC DYSFUNCTION; VASCULAR RESISTANCE;

EID: 79953303266     PISSN: 0066782X     EISSN: 16784170     Source Type: Journal    
DOI: 10.1590/S0066-782X2011005000003     Document Type: Review

References (44)

1. Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, Ganiats TG, et al. ACC/AHA 2005 Guideline update for the diagnosis and management of chronic heart failure in the adult. American College of Cardiology/American Heart Association. Task Force on Practice Guidelines Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure: developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation. 2005; 112 (12): e154-e235.
2. Felker GM, Adams KF Jr, Konstam MA, O'Connor CM, Gheorghiade M. The problem of decompensated heart failure: nomenclature, classification, and risk stratification. Am Heart J. 2003;145 (Suppl 2):18-25.
3. Jessup M, Brozena S. Heart failure. N Engl J Med. 2003; 348 (20): 2007-18.
4. Ramos RB, Fabri J Jr, Mansur A P. A insuficiência cardíaca no Brasil e no mundo e avaliação de sua influência socioeconômica. In: Nobre F, Serrano Jr C V. Tratado de cardiologia SOCESP. São Paulo: Manole; 2005.
5. Guimarães JI, Mesquita ET, Bocchi EA, Vilas-Boas F, Montera MW, Moreira MCV, et al. Revisão das II Diretrizes da Sociedade Brasileira de Cardiologia para o diagnóstico e tratamento da insuficiência cardíaca. Arq Bras Cardiol. 2002; 79 (supl. 4): 1-30.
6. Piepoli M F, Dimopoulos K, Concu A Crisafulli A. Cardiovascular and ventilatory control during exercise in chronic heart failure: role of muscle reflexes. Int J Cardiol. 2008; 130 (1): 3-10.
7. Agostoni P, Contini M, Magini A, Apostolo A, Cattadori G, Bussotti M, et al. Carvedilol reduces exercise-induced hyperventilation: a benefit in normoxia and a problem with hypoxia. Eur J Heart Fail. 2006; 8 (7): 729-735.
8. Kleber FX, Vietzke G, Wernecke KD, Bauer U, Opitz C, Wensel R, et al. Impairment of ventilatory efficiency in heart failure: prognostic impact. Circulation. 2000; 101 (24): 2803-2809.
9. Agostoni P, Pellegrino R, Conca C, Rodarte JR, Brusasco V. Exercise hyperpnea in chronic heart failure: relationships to lung stiffness and expiratory flow limitation. J Appl Physiol. 2002; 92 (4): 1409-1416.
10. Ponikowski P, Chua T P, Francis D P, Capucci A, Coats AJS, Piepoli M F. Muscle ergoreceptor overactivity reflects deterioration in clinical status and cardiorespiratory reflex control in chronic heart failure. Circulation. 2001; 104 (19): 2324-2330.
11. Wang WZ, Gao L, Wang HJ, Zucker IH, Wang W. Interaction between cardiac sympathetic afferent reflex and chemoreflex is mediated by the NTS AT1 receptors in heart failure. Am J Physiol Heart Circ Physiol. 2008; 295 (3): H1216-H1226.
12. Guyton AC, Hall JE. Tratado de fisiologia médica. 11a. ed. São Paulo: Elsevier; 2006.
13. Dibner-Dunlap ME, Smith ML, Kinugawa T, Thames MD. Enalaprilat augments arterial and cardiopulmonary baroreflex control of sympathetic nerve activity in patients with heart failure. J Am Coll Cardiol. 1996; 27 (2): 358-364.
14. Corrêa LMA, Santos TSNP, Moura THP, Negrão CE. Alterações autonômicas na insuficiência cardíaca: benefícios do exercício físico. Rev SOCERJ. 2008; 21 (2): 106-111.
15. Abboud FM, Thames MD. Interaction of cardiovascular reflexes in circulatory control. In: Sheperd J T, Abboud FM, Geiger SR. (editors). Handbook of physiology section 2: the cardiovascular system. Bethesda: American Physiological Society; 1983. p. 557-622.
16. Wade JG, Larson CP Jr, Hickey R F, Ehrenfeld WK, Severinghaus JW. Effect of carotid endarterectomy on carotid chemoreceptor and baroreceptor function in man. N Engl J Med. 1970; 282 (15): 823-829.
17. Lugliani RB, Whipp BJ, Seard C, Wasserman K. Effect of bilateral carotid-body resection on ventilatory control at rest and during exercise in man. N Engl J Med. 1971; 285 (20): 1105-1111.
18. Gelfand R, Lambertsen CJ. Dynamic respiratory response to abrupt change of inspired CO2 at normal and high PO2. J Appl Physiol. 1973; 35 (6): 903-913.
19. Narkiewicz K, Pesek CA, van de Borne PJH, Kato M, Somers VK. Enhanced sympathetic and ventilatory responses to central chemoreflex activation in heart failure. Circulation. 1999; 100 (3): 262-267.
20. Seals DR, Johnson DG, Fregosi R F. Hyperoxia lowers sympathetic nerve activity at rest but not during exercise in humans. Am J Physiol. 1991; 260 (5 Pt 2): R873-R878.
21. Schultz HD, Sun SY. Chemoreflex function in heart failure. Heart Fail Rev. 2000; 5 (1): 45-56.
22. Duffin J. Role of acid-base balance in the chemoreflex control of breathing. J Appl Physiol. 2005; 99 (6): 2255-2265.
23. Ainslie PN, Duffin J. Integration of cerebrovascular CO2 reactivity and chemoreflex control of breathing: mechanisms of regulation, measurement and interpretation. Am J Physiol Regul Integr Comp Physiol. 2009; 296 (5): R1473-R1495.
24. Barrett KM, Ackerman RH, Gahn G, Romero JM, Candia M. Basilar and middle cerebral artery reserve: a comparative study using transcranial Doppler and breathholding techniques. Stroke. 2001; 32 (12): 2793-2796.
25. Atkinson JL, Anderson RE, Sundt TM Jr. The effect of carbon dioxide on the diameter of brain capillaries. Brain Res. 1990; 517 (12): 333-340.
26. Hanly P, Zuberi N, Gray R. Pathogenesis of Cheyne-Stokes respiration in patients with congestive heart failure: relationship to arterial PCO2. Chest. 1993; 104 (4): 1079-1084.
27. Barreto-Filho JAS, Consolim-Colombo FM, Lopes H F, Martins Sobrinho CR, Guerra-Riccio GM, Krieger EM. Dysregulation of peripheral and central chemoreflex responses in chagas' heart disease patients without heart failure. Circulation. 2001; 104 (15): 1792-1798.
28. Barreto Filho JA. Quimiorreflexo na cardiopatia da doença de Chagas. [Tese]. São Paulo: Faculdade de Medicina da Universidade de São Paulo; 1998.
29. De Angelis K, Schaan BA, Rodrigues B, Malfitano C, Irigoyen MC. Disfunção autonômica cardiovascular no diabetes mellitus experimental. Arq Bras Endocrinol Metab. 2007; 51: 2.
30. Weisbrod CJ, Eastwood PR, O'Driscoll G, Green DJ. Abnormal ventilatory responses to hypoxia in Type 2 diabetes. Diab Med. 2005; 22 (5): 563-568.
31. Packer M, Fowler MB, Roecker EB, Coats AJ, Katus HA, Krum H, et al. Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) Study. Circulation. 2002; 106 (17); 2194-2199.
32. The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II) a randomized trial. Lancet. 1999; 353 (9146): 9-13.
33. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet. 1999; 353 (9169): 2001-2007.
34. Greenberg B. Nonselective versus selective beta-blockers in the management of chronic heart failure: clinical implications of the carvedilol or metoprolol European Trial. Rev Cardiovasc Med. 2004; 5 (Suppl 1): S10-S17.
35. Remme WJ. Beta-blockade as first-line therapy in the elderly heart failure patient - the proper approach or asking for trouble? Cardiovasc Drugs Ther. 2008; 22 (5): 347-350.
36. Agostoni P, Contini M, Cattadori G, Apostolo A, Sciomer S, Bussotti M, et al. Lung function with carvedilol and bisoprolol in chronic heart failure: is beta selectivity relevant? Eur J Heart Fail. 2007; 9 (8): 827-833.
37. Puri S, Dutka D P, Baker BL, Hughes JMB, Cleland JGF. Acute saline infusion reduces alveolar-capillary membrane conductance and increases airflow obstruction in patients with left ventricular dysfunction. Circulation. 1999; 99 (9): 1190-1196.
38. Witte KKA, Thackray SRD, Nikitin N P, Cleland JGF, Clark AL. The effects of alpha and beta blockade on ventilatory responses to exercise in chronic heart failure. Heart. 2003; 89 (10): 1169-1173.
39. Prabhakar NR, Peng YJ. Peripheral chemoreceptors in health disease. J Appl Physiol. 2004; 96 (1): 359-366.
40. Reid IA. Interactions between ANG II, sympathetic nervous system, and baroreceptor reflexs in regulation of blood pressure. Am J Physiol. 1992; 262 (6 Pt 1): E763-E778.
41. Li YL, Xia XH, Zheng H, Gao L, Li Y F, Liu D, et al. Angiotensin II enhances carotid body chemoreflex control of sympathetic outflow in chronic heart failure rabbits. Cardiovasc Res. 2006; 71 (1): 129-138.
42. Liu JL, Irvine S, Reid IA, Patel K P, Zucker IH. Chronic exercise reduces sympathetic nerve activity in rabbits with pacing-induced heart failure: a role for angiotensin II. Circulation. 2000; 102 (15): 1854-1862.
43. van deWal RM, Plokker HW, Lok DJ, Boomsma F, van der Horst FA, van Veldhuisen DJ, et al. Determinants of increased angiotensin II levels in severe chronic heart failure patients despite ACE inhibition. Int J Cardiol. 2006; 106 (3): 367-372.
44. Li YL, Schultz HD. Enhanced sensitivity of Kv channels to hypoxia in the rabbit carotid body in heart failure: role of angiotensin II. J Physiol. 2006; 575 (1): 215-227.