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Volumn 2011, Issue , 2011, Pages

Development of novel in silico model to predict corneal permeability for congeneric drugs: A QSPR approach

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CIPROFLOXACIN; GATIFLOXACIN; LEVOFLOXACIN; LOMEFLOXACIN; MOXIFLOXACIN; NORFLOXACIN; OFLOXACIN; PEFLOXACIN; QUINOLONE DERIVATIVE; SPARFLOXACIN; ANTIINFECTIVE AGENT; GENERIC DRUG;

EID: 79953276355     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2011/483869     Document Type: Article
Times cited : (11)

References (28)
  • 2
    • 33751172725 scopus 로고    scopus 로고
    • Drug transport in corneal epithelium and blood-retina barrier: Emerging role of transporters in ocular pharmacokinetics
    • Mannermaa E., Vellonen K. S., Urtti A., Drug transport in corneal epithelium and blood-retina barrier: emerging role of transporters in ocular pharmacokinetics Advanced Drug Delivery Reviews 2006 58 11 1136 1163
    • (2006) Advanced Drug Delivery Reviews , vol.58 , Issue.11 , pp. 1136-1163
    • Mannermaa, E.1    Vellonen, K.S.2    Urtti, A.3
  • 3
    • 15344343054 scopus 로고    scopus 로고
    • In silico ADME modelling: Prediction models for blood-brain barrier permeation using a systematic variable selection method
    • DOI 10.1016/j.bmc.2005.01.061
    • Narayanan R., Gunturi S. B., In silico ADME modelling: prediction models for blood-brain barrier permeation using a systematic variable selection method Bioorganic and Medicinal Chemistry 2005 13 8 3017 3028 (Pubitemid 40392479)
    • (2005) Bioorganic and Medicinal Chemistry , vol.13 , Issue.8 , pp. 3017-3028
    • Narayanan, R.1    Gunturi, S.B.2
  • 4
    • 52049087662 scopus 로고    scopus 로고
    • Molecular design for enhancement of ocular penetration
    • Shirasaki Y., Molecular design for enhancement of ocular penetration Journal of Pharmaceutical Sciences 2008 97 7 2462 2496
    • (2008) Journal of Pharmaceutical Sciences , vol.97 , Issue.7 , pp. 2462-2496
    • Shirasaki, Y.1
  • 5
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • DOI 10.1016/S0169-409X(00)00129-0, PII S0169409X00001290
    • Lipinski C. A., Lombardo F., Dominy B. W., Feeney P. J., Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings Advanced Drug Delivery Reviews 2001 46 1-3 3 26 (Pubitemid 33653411)
    • (2000) Advanced Drug Delivery Reviews , vol.46 , Issue.1-3 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 6
    • 66149144814 scopus 로고    scopus 로고
    • Intraocular penetration of antimicrobial agents in ophthalmic infections and drug delivery strategies
    • Velpandian T., Intraocular penetration of antimicrobial agents in ophthalmic infections and drug delivery strategies Expert Opinion on Drug Delivery 2009 6 3 255 270
    • (2009) Expert Opinion on Drug Delivery , vol.6 , Issue.3 , pp. 255-270
    • Velpandian, T.1
  • 7
    • 31644439691 scopus 로고    scopus 로고
    • MI-QSAR models for prediction of corneal permeability of organic compounds
    • DOI 10.1111/j.1745-7254.2006.00241.x
    • Chen C., Yang J., MI-QSAR models for prediction of corneal permeability of organic compounds Acta Pharmacologica Sinica 2006 27 2 193 204 (Pubitemid 43171158)
    • (2006) Acta Pharmacologica Sinica , vol.27 , Issue.2 , pp. 193-204
    • Chen, C.1    Yang, J.2
  • 8
    • 0021069377 scopus 로고
    • Corneal penetration behavior of β-blocking agents. III: In vitro-in vivo correlations
    • Huang H. S., Schoenwald R. D., Lach J. L., Corneal penetration behavior of -blocking agents. III: in vitro-in vivo correlations Journal of Pharmaceutical Sciences 1983 72 11 1279 1281 (Pubitemid 14229735)
    • (1983) Journal of Pharmaceutical Sciences , vol.72 , Issue.11 , pp. 1279-1281
    • Huang, H.S.1    Schoenwald, R.D.2    Lach, J.L.3
  • 9
    • 0034094140 scopus 로고    scopus 로고
    • Structure-permeability relationships for transcorneal penetration
    • Worth A. P., Cronin M. T. D., Structure-permeability relationships for transcorneal penetration ATLA Alternatives to Laboratory Animals 2000 28 3 403 413 (Pubitemid 30412548)
    • (2000) ATLA Alternatives to Laboratory Animals , vol.28 , Issue.3 , pp. 403-413
    • Worth, A.P.1    Cronin, M.T.D.2
  • 10
    • 0029739972 scopus 로고    scopus 로고
    • Unified model for the corneal permeability of related and diverse compounds with respect to their physicochemical properties
    • DOI 10.1021/js960076m
    • Yoshida F., Topliss J. G., Unified model for the corneal permeability of related and diverse compounds with respect to their physicochemical properties Journal of Pharmaceutical Sciences 1996 85 8 819 823 (Pubitemid 26269475)
    • (1996) Journal of Pharmaceutical Sciences , vol.85 , Issue.8 , pp. 819-823
    • Yoshida, F.1    Topliss, J.G.2
  • 11
    • 0037203658 scopus 로고    scopus 로고
    • A simple model for the prediction of corneal permeability
    • DOI 10.1016/S0378-5173(01)00902-4, PII S0378517301009024
    • Fu X. C., Liang W. Q., A simple model for the prediction of corneal permeability International Journal of Pharmaceutics 2002 232 1-2 193 197 (Pubitemid 34076765)
    • (2002) International Journal of Pharmaceutics , vol.232 , Issue.1-2 , pp. 193-197
    • Fu, X.C.1    Liang, W.Q.2
  • 12
    • 33847405771 scopus 로고    scopus 로고
    • The application of cassette dosing for pharmacokinetic screening in small-molecule cancer drug discovery
    • DOI 10.1158/1535-7163.MCT-06-0324
    • Smith N. F., Raynaud F. I., Workman P., The application of cassette dosing for pharmacokinetic screening in small-molecule cancer drug discovery Molecular Cancer Therapeutics 2007 6 2 428 440 (Pubitemid 46332445)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.2 , pp. 428-440
    • Smith, N.F.1    Raynaud, F.I.2    Workman, P.3
  • 13
    • 33845293253 scopus 로고    scopus 로고
    • Pharmacodynamic Biomarkers for Molecular Cancer Therapeutics
    • DOI 10.1016/S0065-230X(06)96008-4, PII S0065230X06960084
    • Sarker D., Workman P., Pharmacodynamic biomarkers for molecular cancer therapeutics Advances in Cancer Research 2006 96 213 268 (Pubitemid 44873123)
    • (2006) Advances in Cancer Research , vol.96 , pp. 213-268
    • Sarker, D.1    Workman, P.2
  • 14
    • 4444334494 scopus 로고    scopus 로고
    • Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesis
    • Raynaud F. I., Fischer P. M., Nutley B. P., Goddard P. M., Lane D. P., Workman P., Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesis Molecular Cancer Therapeutics 2004 3 3 353 362 (Pubitemid 39193711)
    • (2004) Molecular Cancer Therapeutics , vol.3 , Issue.3 , pp. 353-362
    • Raynaud, F.I.1    Fischer, P.M.2    Nutley, B.P.3    Goddard, P.M.4    Lane, D.P.5    Workman, P.6
  • 15
    • 0037172353 scopus 로고    scopus 로고
    • Simultaneous determination of eight β-blockers by gradient high-performance liquid chromatography with combined ultraviolet and fluorescence detection in corneal permeability studies in vitro
    • DOI 10.1016/S1570-0232(02)00059-4, PII S1570023202000594
    • Ranta V. P., Toropainen E., Talvitie A., Auriola S., Urtti A., Simultaneous determination of eight -blockers by gradient high-performance liquid chromatography with combined ultraviolet and fluorescence detection in corneal permeability studies in vitro Journal of Chromatography B 2002 72 1 81 87 (Pubitemid 34450755)
    • (2002) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.772 , Issue.1 , pp. 81-87
    • Ranta, V.-P.1    Toropainen, E.2    Talvitie, A.3    Auriola, S.4    Urtti, A.5
  • 16
    • 58149189768 scopus 로고    scopus 로고
    • Cassette analysis of eight beta-blockers in bovine eye sclera, choroid-RPE, retina, and vitreous by liquid chromatography-tandem mass spectrometry
    • Kadam R. S., Kompella U. B., Cassette analysis of eight beta-blockers in bovine eye sclera, choroid-RPE, retina, and vitreous by liquid chromatography-tandem mass spectrometry Journal of Chromatography B 2009 877 3 253 260
    • (2009) Journal of Chromatography B , vol.877 , Issue.3 , pp. 253-260
    • Kadam, R.S.1    Kompella, U.B.2
  • 17
    • 52449126581 scopus 로고    scopus 로고
    • Cassette dosing pharmacokinetic studies for evaluation of ophthalmic drugs for posterior ocular diseases
    • Proksch J. W., Ward K. W., Cassette dosing pharmacokinetic studies for evaluation of ophthalmic drugs for posterior ocular diseases Journal of Pharmaceutical Sciences 2008 97 8 3411 3421
    • (2008) Journal of Pharmaceutical Sciences , vol.97 , Issue.8 , pp. 3411-3421
    • Proksch, J.W.1    Ward, K.W.2
  • 19
    • 34548312114 scopus 로고    scopus 로고
    • Ocular toxicity of fluoroquinolones
    • DOI 10.1111/j.1442-9071.2007.01552.x
    • Thompson A. M., Ocular toxicity of fluoroquinolones Clinical and Experimental Ophthalmology 2007 35 6 566 577 (Pubitemid 47337975)
    • (2007) Clinical and Experimental Ophthalmology , vol.35 , Issue.6 , pp. 566-577
    • Thompson, A.M.1
  • 21
    • 0036907858 scopus 로고    scopus 로고
    • Corneal permeation of ganciclovir: Mechanism of ganciclovir permeation enhancement by acyl ester prodrug design
    • Tirucherai G. S., Dias C., Mitra A. K., Corneal permeation of ganciclovir: mechanism of ganciclovir permeation enhancement by acyl ester prodrug design Journal of Ocular Pharmacology and Therapeutics 2002 18 6 535 548 (Pubitemid 36020255)
    • (2002) Journal of Ocular Pharmacology and Therapeutics , vol.18 , Issue.6 , pp. 535-548
    • Tirucherai, G.S.1    Dias, C.2    Mitra, A.K.3
  • 22
    • 0344505694 scopus 로고    scopus 로고
    • Different effects of pH on the permeation of pilocarpine and pilocarpine prodrugs across the isolated rabbit cornea
    • DOI 10.1016/S0928-0987(97)10002-1, PII S0928098797100021
    • Suhonen P., Jrvinen T., Koivisto S., Urtti A., Different effects of pH on the permeation of pilocarpine and pilocarpine prodrugs across the isolated rabbit cornea European Journal of Pharmaceutical Sciences 1998 6 3 169 176 (Pubitemid 28473217)
    • (1998) European Journal of Pharmaceutical Sciences , vol.6 , Issue.3 , pp. 169-176
    • Suhonen, P.1    Jarvinen, T.2    Koivisto, S.3    Urtti, A.4
  • 23
    • 0024246135 scopus 로고
    • Mechanism of transcorneal permeation of pilocarpine
    • DOI 10.1002/jps.2600770911
    • Mitra A. K., Mikkelson T. J., Mechanism of transcorneal permeation of pilocarpine Journal of Pharmaceutical Sciences 1988 77 9 771 775 (Pubitemid 19030312)
    • (1988) Journal of Pharmaceutical Sciences , vol.77 , Issue.9 , pp. 771-775
    • Mitra, A.K.1    Mikkelson, T.J.2
  • 24
    • 0022325722 scopus 로고
    • Corneal penetration and ocular bioavailability of drugs
    • Burstein N. L., Anderson J. A., Corneal penetration and ocular bioavailability of drugs Journal of Ocular Pharmacology 1985 1 3 309 326 (Pubitemid 17187200)
    • (1985) Journal of Ocular Pharmacology , vol.1 , Issue.3 , pp. 309-326
    • Burstein, N.L.1    Anderson, J.A.2
  • 26
    • 0033556471 scopus 로고    scopus 로고
    • Validity of the weighted HOMO-LUMO energy separation as an index of kinetic stability for fullerenes with up to 120 carbon atoms
    • Yoshida M., Aihara J. I., Validity of the weighted HOMO-LUMO energy separation as an index of kinetic stability for fullerenes with up to 120 carbon atoms Physical Chemistry Chemical Physics 1999 1 2 227 230
    • (1999) Physical Chemistry Chemical Physics , vol.1 , Issue.2 , pp. 227-230
    • Yoshida, M.1    Aihara, J.I.2
  • 27
    • 0036589111 scopus 로고    scopus 로고
    • Effective descriptions of molecular structures and the quantitative structureactivity relationship studies
    • Xu LU., Yang J. A., Wu YA. P., Effective descriptions of molecular structures and the quantitative structureactivity relationship studies Journal of Chemical Information and Computer Sciences 2002 42 3 602 606
    • (2002) Journal of Chemical Information and Computer Sciences , vol.42 , Issue.3 , pp. 602-606
    • Xu, L.U.1    Yang, J.A.2    Wu, Y.A.P.3
  • 28
    • 64349101278 scopus 로고    scopus 로고
    • Topological polar surface area defines substrate transport by multidrug resistance associated protein 1 (MRP1/ABCC1)
    • Fernandes J., Gattass C. R., Topological polar surface area defines substrate transport by multidrug resistance associated protein 1 (MRP1/ABCC1) Journal of Medicinal Chemistry 2009 52 4 1214 1218
    • (2009) Journal of Medicinal Chemistry , vol.52 , Issue.4 , pp. 1214-1218
    • Fernandes, J.1    Gattass, C.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.