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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 8, 2011, Pages 2229-2231

Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease

(7) Šilhár, Peter a Alakurtti, Sami b,c Čapková, Kateřina a Xiaochuan, Feng d Shoemaker, Charles B d Yli Kauhaluoma, Jari b Janda, Kim D a

a SCRIPPS RESEARCH INSTITUTE (United States)

b UNIVERSITY OF HELSINKI (Finland)

c VTT TECHNICAL RESEARCH CENTRE OF FINLAND (Finland)

d TUFTS UNIVERSITY (United States)

Author keywords

Betulin derivatives; Botulinum neurotoxin; Protease inhibitor

Indexed keywords

BETULIN; BETULIN DERIVATIVE; BOTULINUM TOXIN A; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50;

ANIMALS; BOTULINUM TOXINS; BOTULINUM TOXINS, TYPE A; NEURONS; PROTEASE INHIBITORS; RATS; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; SUCCINATES; TRITERPENES;

RATTUS;

EID: 79953271166 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2011.02.115 Document Type: Article

Times cited : (13)

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