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Volumn 2011, Issue , 2011, Pages

Herbal medicine and hepatocellular carcinoma: Applications and challenges

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; CURCUMIN; CYCLIN DEPENDENT KINASE 1; CYCLIN E; CYCLINE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; RESVERATROL; SILIBININ; TANSHINONE;

EID: 79953268388     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1093/ecam/neq044     Document Type: Review
Times cited : (64)

References (96)
  • 1
    • 79953289105 scopus 로고
    • Beaconsfield, UK Beaconsfield Publishers
    • Weiss R., What is Herbal Medicine 1988 Beaconsfield, UK Beaconsfield Publishers
    • (1988) What Is Herbal Medicine
    • Weiss, R.1
  • 7
    • 7044272630 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in cirrhosis: Incidence and risk factors
    • Fattovich G., Stroffolini T., Zagni I., Donato F., Hepatocellular carcinoma in cirrhosis: incidence and risk factors Gastroenterology 2004 127 5, supplement 1 S35 S50
    • (2004) Gastroenterology , vol.127 , Issue.5 SUPPL. 1
    • Fattovich, G.1    Stroffolini, T.2    Zagni, I.3    Donato, F.4
  • 8
    • 18144411666 scopus 로고    scopus 로고
    • Updated treatment approach to hepatocellular carcinoma
    • DOI 10.1007/s00535-005-1566-3
    • Llovet J. M., Updated treatment approach to hepatocellular carcinoma Journal of Gastroenterology 2005 40 3 225 235 (Pubitemid 40613379)
    • (2005) Journal of Gastroenterology , vol.40 , Issue.3 , pp. 225-235
    • Llovet, J.M.1
  • 12
    • 0033854015 scopus 로고    scopus 로고
    • Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor - A prospective randomized study of hepatitis C virus - Related liver cancer
    • Ikeda K., Arase Y., Saitoh S., Kobayashi M., Suzuki Y., Suzuki F., Tsubota A., Chayama K., Murashima N., Kumada H., Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumora prospective randomized study of hepatitis C virusrelated liver cancer Hepatology 2000 32 2 228 232 (Pubitemid 30614654)
    • (2000) Hepatology , vol.32 , Issue.2 , pp. 228-232
    • Ikeda, K.1    Arase, Y.2    Saitoh, S.3    Kobayashi, M.4    Suzuki, Y.5    Suzuki, F.6    Tsubota, A.7    Chayama, K.8    Murashima, N.9    Kumada, H.10
  • 13
    • 0346093899 scopus 로고    scopus 로고
    • Prospective randomized controlled study of interferon-alpha in preventing hepatocellular carcinoma recurrence after medical ablation therapy for primary tumors
    • Lin S. M., Lin C. J., Hsu C. W., Tai D. I., Sheen I. S., Lin D. Y., Prospective randomized controlled study of interferon-alpha in preventing hepatocellular carcinoma recurrence after medical ablation therapy for primary tumors Cancer 2004 100 376 382
    • (2004) Cancer , vol.100 , pp. 376-382
    • Lin, S.M.1    Lin, C.J.2    Hsu, C.W.3    Tai, D.I.4    Sheen, I.S.5    Lin, D.Y.6
  • 15
    • 33749608763 scopus 로고    scopus 로고
    • Medical treatments for hepatocellular carcinoma (HCC): What's next?
    • Taieb J., Barbare J. C., Rougier P., Medical treatments for hepatocellular carcinoma (HCC): what's next? Annals of Oncology 2006 17 10 x308 x314
    • (2006) Annals of Oncology , vol.17 , Issue.10
    • Taieb, J.1    Barbare, J.C.2    Rougier, P.3
  • 16
    • 0037308133 scopus 로고    scopus 로고
    • Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival
    • DOI 10.1053/jhep.2003.50047
    • Llovet J. M., Bruix J., Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival Hepatology 2003 37 2 429 442 (Pubitemid 36152543)
    • (2003) Hepatology , vol.37 , Issue.2 , pp. 429-442
    • Llovet, J.M.1    Bruix, J.2
  • 17
    • 33646567160 scopus 로고    scopus 로고
    • Systematic review: Evidence-based management of hepatocellular carcinoma - An updated analysis of randomized controlled trials
    • DOI 10.1111/j.1365-2036.2006.02932.x
    • Lopez P. M., Villanueva A., Llovet J. M., Systematic review: evidence-based management of hepatocellular carcinomaan updated analysis of randomized controlled trials Alimentary Pharmacology Therapeutics 2006 23 1535 1547 (Pubitemid 43727460)
    • (2006) Alimentary Pharmacology and Therapeutics , vol.23 , Issue.11 , pp. 1535-1547
    • Lopez, P.M.1    Villanueva, A.2    Llovet, J.M.3
  • 19
    • 23344434285 scopus 로고    scopus 로고
    • Herbal medicine and cancer: An introductory overview
    • DOI 10.1016/j.soncn.2005.04.006, PII S0749208105000379
    • Treasure J., Herbal medicine and cancer: an introductory overview Seminars in Oncology Nursing 2005 21 3 177 183 (Pubitemid 41104990)
    • (2005) Seminars in Oncology Nursing , vol.21 , Issue.3 , pp. 177-183
    • Treasure, J.1
  • 20
    • 34547908170 scopus 로고    scopus 로고
    • Traditional Chinese herbal medicines for treatment of liver fibrosis and cancer: From laboratory discovery to clinical evaluation
    • DOI 10.1111/j.1478-3231.2007.01527.x
    • Luk J. M., Wang X., Liu P., Wong K.-F., Chan K.-L., Tong Y., Hui C.-K., Lau G. K., Fan S.-T., Traditional Chinese herbal medicines for treatment of liver fibrosis and cancer: from laboratory discovery to clinical evaluation Liver International 2007 27 7 879 890 (Pubitemid 47261940)
    • (2007) Liver International , vol.27 , Issue.7 , pp. 879-890
    • Luk, J.M.1    Wang, X.2    Liu, P.3    Wong, K.-F.4    Chan, K.-L.5    Tong, Y.6    Hui, C.-K.7    Lau, G.K.8    Fan, S.-T.9
  • 21
    • 33947282103 scopus 로고    scopus 로고
    • Herbal medicine in the treatment of liver diseases
    • DOI 10.1016/j.dld.2006.11.004, PII S1590865806005974
    • Stickel F., Schuppan D., Herbal medicine in the treatment of liver diseases Digestive and Liver Disease 2007 39 4 293 304 (Pubitemid 46432239)
    • (2007) Digestive and Liver Disease , vol.39 , Issue.4 , pp. 293-304
    • Stickel, F.1    Schuppan, D.2
  • 22
    • 0035008526 scopus 로고    scopus 로고
    • Herbal and complementary and alternative medicine therapies for liver disease: A focus on Chinese traditional medicine in hepatitis C virus
    • Cohen M. R., Herbal and complementary and alternative medicine therapies for liver disease: a focus on Chinese traditional medicine in hepatitis C virus Clinics in Liver Disease 2001 5 2 461 478 (Pubitemid 32475750)
    • (2001) Clinics in Liver Disease , vol.5 , Issue.2 , pp. 461-478
    • Cohen, M.R.1
  • 23
    • 3042822166 scopus 로고    scopus 로고
    • Generality of sera-pharmacologic experimental study on effect of Chinese herbal medicine on liver stellate cells
    • Zhou B., Yao N. L., Generality of sera-pharmacologic experimental study on effect of Chinese herbal medicine on liver stellate cells Zhongguo Zhong Xi Yi Jie He Za Zhi 2004 24 4 376 379
    • (2004) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.24 , Issue.4 , pp. 376-379
    • Zhou, B.1    Yao, N.L.2
  • 24
    • 0033610734 scopus 로고    scopus 로고
    • Improving the quality of reports of meta-analyses of randomised controlled trials: The QUOROM statement. Quality of reporting of meta-analyses
    • Moher D., Cook D. J., Eastwood S., Olkin I., Rennie D., Stroup D. F., Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of reporting of meta-analyses Lancet 1999 354 1896 1900
    • (1999) Lancet , vol.354 , pp. 1896-1900
    • Moher, D.1    Cook, D.J.2    Eastwood, S.3    Olkin, I.4    Rennie, D.5    Stroup, D.F.6
  • 26
    • 4444299322 scopus 로고    scopus 로고
    • Molecular targets for bioactive food components
    • Milner J. A., Molecular targets for bioactive food components Journal of Nutrition 2004 134 9 2492S 2498S (Pubitemid 39201626)
    • (2004) Journal of Nutrition , vol.134 , Issue.9
    • Milner, J.A.1
  • 27
    • 53449094405 scopus 로고    scopus 로고
    • Anticancer and carcinogenic properties of curcumin: Considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent
    • Lpez-Lzaro M., Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent Molecular Nutrition and Food Research 2008 52 supplement 1 S103 S127
    • (2008) Molecular Nutrition and Food Research , vol.52 , Issue.SUPPL. 1
    • Lpez-Lzaro, M.1
  • 28
    • 0033969490 scopus 로고    scopus 로고
    • Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis
    • Chuang S. E., Kuo M. L., Hsu C. H., Chen C. R., Lin J. K., Lai G. M., Hsieh C. Y., Cheng A. L., Curcumin-containing diet inhibits diethylnitrosamine- induced murine hepatocarcinogenesis Carcinogenesis 2000 21 2 331 335 (Pubitemid 30098723)
    • (2000) Carcinogenesis , vol.21 , Issue.2 , pp. 331-335
    • Chuang, S.E.1    Kuo, M.L.2    Hsu, C.H.3    Chen, C.R.4    Lin, J.K.5    Lai, G.M.6    Hsieh, C.Y.7    Cheng, A.L.8
  • 29
    • 0033801316 scopus 로고    scopus 로고
    • Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in rats
    • Chuang S.-E., Cheng A.-L., Lin J.-K., Kuo M.-L., Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in rats Food and Chemical Toxicology 2000 38 11 991 995
    • (2000) Food and Chemical Toxicology , vol.38 , Issue.11 , pp. 991-995
    • Chuang, S.-E.1    Cheng, A.-L.2    Lin, J.-K.3    Kuo, M.-L.4
  • 30
    • 44849122833 scopus 로고    scopus 로고
    • Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice
    • DOI 10.3748/wjg.14.2003
    • Yoysungnoen P., Wirachwong P., Changtam C., Suksamrarn A., Patumraj S., Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice World Journal of Gastroenterology 2008 14 2003 2009 (Pubitemid 351795819)
    • (2008) World Journal of Gastroenterology , vol.14 , Issue.13 , pp. 2003-2009
    • Yoysungnoen, P.1    Wirachwong, P.2    Changtam, C.3    Suksamram, A.4    Patumraj, S.5
  • 31
    • 33644797877 scopus 로고    scopus 로고
    • Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice
    • Yoysungnoen P., Wirachwong P., Bhattarakosol P., Niimi H., Patumraj S., Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice Clinical Hemorheology and Microcirculation 2006 34 1-2 109 115 (Pubitemid 43351018)
    • (2006) Clinical Hemorheology and Microcirculation , vol.34 , Issue.1-2 , pp. 109-115
    • Yoysungnoen, P.1    Wirachwong, P.2    Bhattarakosol, P.3    Niimi, H.4    Patumraj, S.5
  • 33
    • 0345600100 scopus 로고    scopus 로고
    • Prevention of intrahepatic metastasis by curcumin in an orthotopic implantation model
    • DOI 10.1159/000074478
    • Ohashi Y., Tsuchiya Y., Koizumi K., Sakurai H., Saiki I., Prevention of intrahepatic metastasis by curcumin in an orthotopic implantation model Oncology 2003 65 3 250 258 (Pubitemid 37505833)
    • (2003) Oncology , vol.65 , Issue.3 , pp. 250-258
    • Ohashi, Y.1    Tsuchiya, Y.2    Koizumi, K.3    Sakurai, H.4    Saiki, I.5
  • 34
    • 0031813252 scopus 로고    scopus 로고
    • Curcumin inhibits SK-Hep-1 hepatocellular carcinoma cell invasion in vitro and suppresses matrix metalloproteinase-9 secretion
    • DOI 10.1159/000011876
    • Lin L.-I., Ke Y.-F., Ko Y.-C., Lin J.-K., Curcumin inhibits SK-Hep-1 hepatocellular carcinoma cell invasion in vitro and suppresses matrix metalloproteinase-9 secretion Oncology 1998 55 4 349 353 (Pubitemid 28279679)
    • (1998) Oncology , vol.55 , Issue.4 , pp. 349-353
    • Lin, L.-I.1    Ke, Y.-F.2    Ko, Y.-C.3    Lin, J.-K.4
  • 35
    • 36949025488 scopus 로고    scopus 로고
    • Inhibition of curcumin on histone deacetylase and expression promotion of P21 (WAF1/CIP1) in HepG2 cells
    • Lv B. H., Zhang L., Zhu C. C., Liu J., [Inhibition of curcumin on histone deacetylase and expression promotion of P21 (WAF1/CIP1) in HepG2 cells] Zhongguo Zhong Yao Za Zhi 2007 32 2051 2055
    • (2007) Zhongguo Zhong Yao Za Zhi , vol.32 , pp. 2051-2055
    • Lv, B.H.1    Zhang, L.2    Zhu, C.C.3    Liu, J.4
  • 36
    • 34547657453 scopus 로고    scopus 로고
    • Curcumin induces apoptosis through mitochondrial hyperpolarization and mtDNA damage in human hepatoma G2 cells
    • DOI 10.1016/j.freeradbiomed.2007.06.006, PII S0891584907003917
    • Cao J., Liu Y., Jia L., Zhou H. M., Kong Y., Yang G., Curcumin induces apoptosis through mitochondrial hyperpolarization and mtDNA damage in human hepatoma G2 cells Free Radical Biology Medicine 2007 43 968 975 (Pubitemid 47223632)
    • (2007) Free Radical Biology and Medicine , vol.43 , Issue.6 , pp. 968-975
    • Cao, J.1    Liu, Y.2    Jia, L.3    Zhou, H.-M.4    Kong, Y.5    Yang, G.6    Jiang, L.-P.7    Li, Q.-J.8    Zhong, L.-F.9
  • 37
    • 33744805811 scopus 로고    scopus 로고
    • Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells
    • DOI 10.1093/toxsci/kfj153
    • Cao J., Jia L., Zhou H.-M., Liu Y., Zhong L.-F., Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells Toxicological Sciences 2006 91 2 476 483 (Pubitemid 43827300)
    • (2006) Toxicological Sciences , vol.91 , Issue.2 , pp. 476-483
    • Cao, J.1    Jia, L.2    Zhou, H.-M.3    Liu, Y.4    Zhong, L.-F.5
  • 38
    • 22044441361 scopus 로고    scopus 로고
    • Curcumin inhibits ROS formation and apoptosis in methylglyoxal-treated human hepatoma G2 cells
    • DOI 10.1196/annals.1338.057
    • Chan W.-H., Wu H.-J., Hsuuw Y.-D., Curcumin inhibits ROS formation and apoptosis in methylglyoxal-treated human hepatoma G2 cells Annals of the New York Academy of Sciences 2005 1042 372 378 (Pubitemid 40967659)
    • (2005) Annals of the New York Academy of Sciences , vol.1042 , pp. 372-378
    • Chan, W.-H.1    Wu, H.-J.2    Hsuuw, Y.-D.3
  • 39
    • 0019421988 scopus 로고
    • In vitro studies on the intestinal absorption of curcumin in rats
    • DOI 10.1016/0300-483X(81)90056-1
    • Ravindranath V., Chandrasekhara N., In vitro studies on the intestinal absorption of curcumin in rats Toxicology 1981 20 2-3 251 257 (Pubitemid 11117911)
    • (1981) Toxicology , vol.20 , Issue.2-3 , pp. 251-257
    • Ravindranath, V.1    Chandrasekhara, N.2
  • 40
    • 0038043190 scopus 로고    scopus 로고
    • Efficacy and irritancy of enhancers on the in-vitro and in-vivo percutaneous absorption of curcumin
    • DOI 10.1211/002235703765344496
    • Fang J.-Y., Hung C.-F., Chiu H.-C., Wang J.-J., Chan T.-F., Efficacy and irritancy of enhancers on the in-vitro and in-vivo percutaneous absorption of curcumin Journal of Pharmacy and Pharmacology 2003 55 5 593 601 (Pubitemid 36705570)
    • (2003) Journal of Pharmacy and Pharmacology , vol.55 , Issue.5 , pp. 593-601
    • Fang, J.-Y.1    Hung, C.-F.2    Chiu, H.-C.3    Wang, J.-J.4    Chan, T.-F.5
  • 42
    • 62549154478 scopus 로고    scopus 로고
    • Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: Inhibition of cell proliferation and induction of apoptosis
    • Bishayee A., Dhir N., Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis Chemico-Biological Interactions 2008 179 131 144
    • (2008) Chemico-Biological Interactions , vol.179 , pp. 131-144
    • Bishayee, A.1    Dhir, N.2
  • 43
    • 33751058881 scopus 로고    scopus 로고
    • Time- and concentration-dependent effects of resveratrol in HL-60 and HepG2 cells
    • DOI 10.1111/j.1365-2184.2006.00406.x
    • Stervbo U., Vang O., Bonnesen C., Time- and concentration-dependent effects of resveratrol in HL-60 and HepG2 cells Cell Proliferation 2006 39 6 479 493 (Pubitemid 44760200)
    • (2006) Cell Proliferation , vol.39 , Issue.6 , pp. 479-493
    • Stervbo, U.1    Vang, O.2    Bonnesen, C.3
  • 44
    • 33750513819 scopus 로고    scopus 로고
    • Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest, and NOS activation
    • DOI 10.1016/j.bbagen.2006.09.010, PII S0304416506002868
    • Notas G., Nifli A.-P., Kampa M., Vercauteren J., Kouroumalis E., Castanas E., Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest, and NOS activation Biochimica et Biophysica Acta 2006 1760 11 1657 1666 (Pubitemid 44667277)
    • (2006) Biochimica et Biophysica Acta - General Subjects , vol.1760 , Issue.11 , pp. 1657-1666
    • Notas, G.1    Nifli, A.-P.2    Kampa, M.3    Vercauteren, J.4    Kouroumalis, E.5    Castanas, E.6
  • 45
    • 42449140345 scopus 로고    scopus 로고
    • Effects of resveratrol on growth inhibition and gap-junctional intercellular communication of HepG2 cells
    • Yan F., Tian X. M., Ma X. D., Effects of resveratrol on growth inhibition and gap-junctional intercellular communication of HepG2 cells Nan Fang Yi Ke Da Xue Xue Bao 2006 26 7 963 966
    • (2006) Nan Fang Yi Ke da Xue Xue Bao , vol.26 , Issue.7 , pp. 963-966
    • Yan, F.1    Tian, X.M.2    Ma, X.D.3
  • 47
    • 46049093970 scopus 로고    scopus 로고
    • Resveratrol inhibits tumor necrosis factor-α-mediated matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells
    • DOI 10.1016/j.biopha.2007.09.006, PII S0753332207002119
    • Yu H., Pan C., Zhao S., Wang Z., Zhang H., Wu W., Resveratrol inhibits tumor necrosis factor- -mediated matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells Biomedicine and Pharmacotherapy 2008 62 6 366 372 (Pubitemid 351899097)
    • (2008) Biomedicine and Pharmacotherapy , vol.62 , Issue.6 , pp. 366-372
    • Yu, H.1    Pan, C.2    Zhao, S.3    Wang, Z.4    Zhang, H.5    Wu, W.6
  • 48
    • 0037813163 scopus 로고    scopus 로고
    • Hypolipidemic action of dietary resveratrol, a phytoalexin in grapes and red wine, in hepatoma-bearing rats
    • DOI 10.1016/S0024-3205(03)00469-7
    • Miura D., Miura Y., Yagasaki K., Hypolipidemic action of dietary resveratrol, a phytoalexin in grapes and red wine, in hepatoma-bearing rats Life Sciences 2003 73 11 1393 1400 (Pubitemid 36798126)
    • (2003) Life Sciences , vol.73 , Issue.11 , pp. 1393-1400
    • Miura, D.1    Miura, Y.2    Yagasaki, K.3
  • 49
    • 12444322028 scopus 로고    scopus 로고
    • Resveratrol inhibits hepatoma cell invasion by suppressing gene expression of hepatocyte growth factor via its reactive oxygen species-scavenging property
    • Miura D., Miura Y., Yagasaki K., Resveratrol inhibits hepatoma cell invasion by suppressing gene expression of hepatocyte growth factor via its reactive oxygen species-scavenging property Clinical Experimental Metastasis 2004 21 445 451
    • (2004) Clinical Experimental Metastasis , vol.21 , pp. 445-451
    • Miura, D.1    Miura, Y.2    Yagasaki, K.3
  • 50
    • 9444296057 scopus 로고    scopus 로고
    • High absorption but very low bioavailability of oral resveratrol in humans
    • DOI 10.1124/dmd.104.000885
    • Walle T., Hsieh F., DeLegge M. H., Oatis J. E. Jr., Walle U. K., High absorption but very low bioavailability of oral resveratrol in humans Drug Metabolism and Disposition 2004 32 12 1377 1382 (Pubitemid 39564557)
    • (2004) Drug Metabolism and Disposition , vol.32 , Issue.12 , pp. 1377-1382
    • Walle, T.1    Hsieh, F.2    DeLegge, M.H.3    Oatis Jr., J.E.4    Walle, U.K.5
  • 52
    • 0037109597 scopus 로고    scopus 로고
    • Milk thistle for the treatment of liver disease: A systematic review and meta-analysis
    • DOI 10.1016/S0002-9343(02)01244-5, PII S0002934302012445
    • Jacobs B. P., Dennehy C., Ramirez G., Sapp J., Lawrence V. A., Milk thistle for the treatment of liver disease: a systematic review and meta-analysis American Journal of Medicine 2002 113 6 506 515 (Pubitemid 35335804)
    • (2002) American Journal of Medicine , vol.113 , Issue.6 , pp. 506-515
    • Jacobs, B.P.1    Dennehy, C.2    Ramirez, G.3    Sapp, J.4    Lawrence, V.A.5
  • 53
    • 0141566797 scopus 로고    scopus 로고
    • Silymarin retards the progression of alcohol-induced hepatic fibrosis in baboons
    • DOI 10.1097/00004836-200310000-00013
    • Lieber C. S., Leo M. A., Cao Q., Ren C., DeCarli L. M., Silymarin retards the progression of alcohol-induced hepatic fibrosis in baboons Journal of Clinical Gastroenterology 2003 37 4 336 339 (Pubitemid 37158997)
    • (2003) Journal of Clinical Gastroenterology , vol.37 , Issue.4 , pp. 336-339
    • Lieber, C.S.1    Leo, M.A.2    Cao, Q.3    Ren, C.4    DeCarli, L.M.5
  • 54
    • 0034859659 scopus 로고    scopus 로고
    • Silymarin: A review of its clinical properties in the management of hepatic disorders
    • Wellington K., Jarvis B., Silymarin: a review of its clinical properties in the management of hepaticdisorders BioDrugs 2001 15 465 489 (Pubitemid 32783707)
    • (2001) BioDrugs , vol.15 , Issue.7 , pp. 465-489
    • Wellington, K.1    Adis, B.J.2
  • 55
    • 33745002041 scopus 로고    scopus 로고
    • Prostate cancer chemoprevention by silibinin: Bench to bedside
    • DOI 10.1002/mc.20223
    • Singh R. P., Agarwal R., Prostate cancer chemoprevention by silibinin: bench to bedside Molecular Carcinogenesis 2006 45 6 436 442 (Pubitemid 43865852)
    • (2006) Molecular Carcinogenesis , vol.45 , Issue.6 , pp. 436-442
    • Singh, R.P.1    Agarwal, R.2
  • 56
    • 27644439523 scopus 로고    scopus 로고
    • Mechanisms and preclinical efficacy of silibinin in preventing skin cancer
    • DOI 10.1016/j.ejca.2005.03.033
    • Singh R. P., Agarwal R., Mechanisms and preclinical efficacy of silibinin in preventing skin cancer European Journal of Cancer 2005 41 13 1969 1979 (Pubitemid 41557682)
    • (2005) European Journal of Cancer , vol.41 , Issue.13 , pp. 1969-1979
    • Singh, R.P.1    Agarwal, R.2
  • 57
    • 28544439164 scopus 로고    scopus 로고
    • Silibinin efficacy against human hepatocellular carcinoma
    • DOI 10.1158/1078-0432.CCR-05-1646
    • Varghese L., Agarwal C., Tyagi A., Singh R. P., Agarwal R., Silibinin efficacy against human hepatocellular carcinoma Clinical Cancer Research 2005 11 23 8441 8448 (Pubitemid 41746959)
    • (2005) Clinical Cancer Research , vol.11 , Issue.23 , pp. 8441-8448
    • Varghese, L.1    Agarwal, C.2    Tyagi, A.3    Singh, R.P.4    Agarwal, R.5
  • 58
    • 35248859158 scopus 로고    scopus 로고
    • Effects and mechanisms of silibinin on human hepatoma cell lines
    • Lah J. J., Cui W., Hu K.-Q., Effects and mechanisms of silibinin on human hepatoma cell lines World Journal of Gastroenterology 2007 13 40 5299 5305 (Pubitemid 47559458)
    • (2007) World Journal of Gastroenterology , vol.13 , Issue.40 , pp. 5299-5305
    • Lah, J.J.1    Cui, W.2    Hu, K.-Q.3
  • 59
    • 48749115799 scopus 로고    scopus 로고
    • Effects of silibinin on cell growth and invasive properties of a human hepatocellular carcinoma cell line, HepG-2, through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation
    • Momeny M., Khorramizadeh M. R., Ghaffari S. H., Yousefi M., Yekaninejad M. S., Esmaeili R., Effects of silibinin on cell growth and invasive properties of a human hepatocellular carcinoma cell line, HepG-2, through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation European Journal of Pharmacology 2008 591 13 20
    • (2008) European Journal of Pharmacology , vol.591 , pp. 13-20
    • Momeny, M.1    Khorramizadeh, M.R.2    Ghaffari, S.H.3    Yousefi, M.4    Yekaninejad, M.S.5    Esmaeili, R.6
  • 60
    • 0029911616 scopus 로고    scopus 로고
    • Effect of natural antioxidant Tanshinone II-A on DNA damage by lipid peroxidation in liver cells
    • DOI 10.1016/0891-5849(95)02211-2
    • Cao E.-H., Liu X.-Q., Wang J.-J., Xu N.-F., Effect of natural antioxidant Tanshinone II-A on DNA damage by lipid peroxidation in liver cells Free Radical Biology and Medicine 1996 20 6 801 806 (Pubitemid 26123854)
    • (1996) Free Radical Biology and Medicine , vol.20 , Issue.6 , pp. 801-806
    • Cao, E.-H.1    Liu, X.-Q.2    Wang, J.-J.3    Xu, N.-F.4
  • 61
    • 0029829044 scopus 로고    scopus 로고
    • Scavenging effects of Salvia miltiorrhiza on free radicals and its protection for myocardial mitochondrial membranes from ischemia-reperfusion injury
    • Zhao B.-L., Jiang W., Zhao Y., Hou J.-W., Xin W.-J., Scavenging effects of Salvia miltiorrhiza on free radicals and its protection for myocardial mitochondrial membranes from ischemia-reperfusion injury Biochemistry and Molecular Biology International 1996 38 6 1171 1182 (Pubitemid 26334731)
    • (1996) Biochemistry and Molecular Biology International , vol.38 , Issue.6 , pp. 1171-1182
    • Zhao, B.-L.1    Jiang, W.2    Zhao, Y.3    Hou, J.-W.4    Xin, W.-J.5
  • 62
    • 0026309074 scopus 로고
    • Cytotoxic activities of tanshinones against human carcinoma cell lines
    • Wu W. L., Chang W. L., Chen C. F., Cytotoxic activities of tanshinones against human carcinoma cell lines American Journal of Chinese Medicine 1991 19 3-4 207 216
    • (1991) American Journal of Chinese Medicine , vol.19 , Issue.34 , pp. 207-216
    • Wu, W.L.1    Chang, W.L.2    Chen, C.F.3
  • 63
    • 0030810489 scopus 로고    scopus 로고
    • In vitro cytotoxicity of tanshinones from Salvia miltiorrhiza
    • DOI 10.1055/s-2006-957696
    • Ryu S. Y., Lee C. O., Choi S. U., In vitro cytotoxicity of tanshinones from Salvia miltiorrhiza Planta Medica 1997 63 4 339 342 (Pubitemid 27322428)
    • (1997) Planta Medica , vol.63 , Issue.4 , pp. 339-342
    • Ryu, S.Y.1    Lee, C.O.2    Choi, S.U.3
  • 64
    • 4043125279 scopus 로고    scopus 로고
    • Growth inhibition and apoptosis induction of tanshinone II-A on human hepatocellular carcinoma cells
    • Yuan S. L., Wei Y. Q., Wang X. J., Xiao F., Li S. F., Zhang J., Growth inhibition and apoptosis induction of tanshinone II-A on human hepatocellular carcinoma cells World Journal of Gastroenterology 2004 10 2024 2028 (Pubitemid 39106951)
    • (2004) World Journal of Gastroenterology , vol.10 , Issue.14 , pp. 2024-2028
    • Yuan, S.-L.1    Wei, Y.-Q.2    Wang, X.-J.3    Xiao, F.4    Li, S.-F.5    Zhang, J.6
  • 65
    • 33947580401 scopus 로고    scopus 로고
    • Inhibition of cell growth and induction of apoptosis in human hepatoma cell line HepG2 by tanshione IIA
    • Zhong Z. H., Chen W. G., Liu Y. H., Li Q. X., Qiu Y., Inhibition of cell growth and induction of apoptosis in human hepatoma cell line HepG2 by tanshione IIA Zhong Nan Da Xue Xue Bao Yi Xue Ban 2007 32 99 103
    • (2007) Zhong Nan da Xue Xue Bao Yi Xue Ban , vol.32 , pp. 99-103
    • Zhong, Z.H.1    Chen, W.G.2    Liu, Y.H.3    Li, Q.X.4    Qiu, Y.5
  • 67
    • 0030473659 scopus 로고    scopus 로고
    • An observation of the effect of Tanshinone on cancer cell proliferation by Brdu and PCNA labeling
    • Wang X., Yuan S., Huang R., Song Y., [An observation of the effect of tanshinone on cancer cell proliferation by Brdu and PCNA labeling] Hua Xi Yi Ke Da Xue Xue Bao 1996 27 388 391 (Pubitemid 27028572)
    • (1996) Journal of West China University of Medical Sciences , vol.27 , Issue.4 , pp. 388-391
    • Wang, X.1    Yuan, S.2    Huang, R.3    Song, Y.4
  • 68
    • 0030274659 scopus 로고    scopus 로고
    • A preliminary study of the anti-cancer effect of tanshinone on hepatic carcinoma and its mechanism of action in mice
    • Wang X., Yuan S., Wang C., A preliminary study of the anti-cancer effect of tanshinone on hepatic carcinoma and its mechanism of action in mice Zhonghua Zhong Liu Za Zhi 1996 18 6 412 414
    • (1996) Zhonghua Zhong Liu Za Zhi , vol.18 , Issue.6 , pp. 412-414
    • Wang, X.1    Yuan, S.2    Wang, C.3
  • 69
    • 56349115456 scopus 로고    scopus 로고
    • Novel polymeric nanoparticles containing tanshinone IIA for the treatment of hepatoma
    • Li Q., Wang Y., Feng N., Fan Z., Sun J., Nan Y., Novel polymeric nanoparticles containing tanshinone IIA for the treatment of hepatoma Journal of Drug Targeting 2008 16 10 725 732
    • (2008) Journal of Drug Targeting , vol.16 , Issue.10 , pp. 725-732
    • Li, Q.1    Wang, Y.2    Feng, N.3    Fan, Z.4    Sun, J.5    Nan, Y.6
  • 70
    • 0027605565 scopus 로고
    • Effects of magnesium lithospermate B on D-galactosamine induced rat liver injury
    • Liu P., Mizoguchi Y., Morisawa S., Effects of magnesium lithospermate B on D-galactosamine induced rat liver injury Zhongguo Zhong Xi Yi Jie He Za Zhi 1993 13 6 352 326
    • (1993) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.13 , Issue.6 , pp. 352-326
    • Liu, P.1    Mizoguchi, Y.2    Morisawa, S.3
  • 73
    • 33751087748 scopus 로고    scopus 로고
    • Enhancing the efficacy of photodynamic therapy by a Chinese herbal medicine for hepatocellular carcinoma
    • Juan M., Minhu C., Yun D., Liang Q., Enhancing the efficacy of photodynamic therapy by a Chinese herbal medicine for hepatocellular carcinoma Cancer Biology and Therapy 2006 5 9 1117 1119 (Pubitemid 44772224)
    • (2006) Cancer Biology and Therapy , vol.5 , Issue.9 , pp. 1117-1119
    • Juan, M.1    Minhu, C.2    Yun, D.3    Liang, Q.4
  • 74
    • 33751081806 scopus 로고    scopus 로고
    • Pheophorbide a, an active compound isolated from Scutellaria barbata, possesses photodynamic activities by inducing apoptosis in human hepatocellular carcinoma
    • Tang P. M.-K., Chan J. Y.-W., Au S. W.-N., Kong S.-K., Tsui S. K.-W., Waye M. M.-Y., Mak T. C.-W., Fong W.-P., Fung K.-P., Pheophorbide a, an active compound isolated from Scutellaria barbata, possesses photodynamic activities by inducing apoptosis in human hepatocellular carcinoma Cancer Biology and Therapy 2006 5 9 1111 1116 (Pubitemid 44772223)
    • (2006) Cancer Biology and Therapy , vol.5 , Issue.9 , pp. 1111-1116
    • Tang, P.M.-K.1    Chan, J.Y.-W.2    Au, S.W.-N.3    Kong, S.-K.4    Tsui, S.K.-W.5    Waye, M.M.-Y.6    Mak, T.C.-W.7    Fong, W.-P.8    Fung, K.-P.9
  • 77
    • 0027570811 scopus 로고
    • Anti-growth effects with components of Sho-saiko-to (TJ-9) on cultured human hepatoma cells
    • Okita K., Li Q., Murakamio T., Takahashi M., Anti-growth effects with components of Sho-saiko-to (TJ-9) on cultured human hepatoma cells European Journal of Cancer Prevention) 1993 2 2 169 175
    • (1993) European Journal of Cancer Prevention) , vol.2 , Issue.2 , pp. 169-175
    • Okita, K.1    Li, Q.2    Murakamio, T.3    Takahashi, M.4
  • 79
    • 3042600731 scopus 로고    scopus 로고
    • Inhibitory effect of Sihoga-Yonggol-Moryo-Tang on matrix metalloproteinase-2 and -9 activities and invasiveness potential of hepatocellular carcinoma
    • DOI 10.1016/j.phrs.2004.02.006, PII S1043661804000520
    • Ha K.-T., Kim J.-K., Kang S.-K., Kim D.-W., Lee Y.-C., Kim H.-M., Kim C.-H., Inhibitory effect of Sihoga-Yonggol-Moryo-Tang on matrix metalloproteinase-2 and -9 activities and invasiveness potential of hepatocellular carcinoma Pharmacological Research 2004 50 3 279 285 (Pubitemid 38844482)
    • (2004) Pharmacological Research , vol.50 , Issue.3 , pp. 279-285
    • Ha, K.-T.1    Kim, J.-K.2    Kang, S.-K.3    Kim, D.-W.4    Lee, Y.-C.5    Kim, H.-M.6    Kim, C.-H.7
  • 80
    • 0034819804 scopus 로고    scopus 로고
    • Effects of lycopene and Sho-saiko-to on hepatocarcinogenesis in a rat model of spontaneous liver cancer
    • Watanabe S., Kitade Y., Masaki T., Nishioka M., Satoh K., Nishino H., Effects of lycopene and Sho-saiko-to on hepatocarcinogenesis in a rat model of spontaneous liver cancer Nutrition and Cancer 2001 39 1 96 101 (Pubitemid 32880954)
    • (2001) Nutrition and Cancer , vol.39 , Issue.1 , pp. 96-101
    • Watanabe, S.1    Kitade, Y.2    Masaki, T.3    Nishioka, M.4    Satoh, K.5    Nishino, H.6
  • 81
    • 0033679130 scopus 로고    scopus 로고
    • Immunomodulation of Bu-Zhong-Yi-Qi-Tang on in vitro granulocyte colony-stimulating-factor and tumor necrosis factor-alpha production by peripheral blood mononuclear cells
    • Kao S. T., Yang S. L., Hsieh C. C., Yang M. D., Wang T. F., Lin J. G., Immunomodulation of Bu-Zhong-Yi-Qi-Tang on in vitro granulocyte colony-stimulating-factor and tumor necrosis factor-alpha production by peripheral blood mononuclear cells Immunopharmacology and Immunotoxicology 2000 22 711 720
    • (2000) Immunopharmacology and Immunotoxicology , vol.22 , pp. 711-720
    • Kao, S.T.1    Yang, S.L.2    Hsieh, C.C.3    Yang, M.D.4    Wang, T.F.5    Lin, J.G.6
  • 82
    • 22144465154 scopus 로고    scopus 로고
    • Clinical study on treatment of primary hepatocellular carcinoma by Shenqi mixture combined with microwave coagulation
    • Lin J.-J., Jin C.-N., Zheng M.-L., Ouyang X.-N., Zeng J.-X., Dai X.-H., Clinical study on treatment of primary hepatocellular carcinoma by Shenqi mixture combined with microwave coagulation Chinese Journal of Integrative Medicine 2005 11 2 104 110 (Pubitemid 40980084)
    • (2005) Chinese Journal of Integrative Medicine , vol.11 , Issue.2 , pp. 104-110
    • Lin, J.-J.1    Jin, C.-N.2    Zheng, M.-L.3    Ouyang, X.-N.4    Zeng, J.-X.5    Dai, X.-H.6
  • 83
    • 0037799654 scopus 로고    scopus 로고
    • Experimental study on xiaoliu pingyi mixture with medicated serum in inducing apoptosis of human hepatocellular carcinoma cell line H-7402
    • Li X. R., Zhang D., Qi Y. F., Experimental study on xiaoliu pingyi mixture with medicated serum in inducing apoptosis of human hepatocellular carcinoma cell line H-7402 Zhongguo Zhong Xi Yi Jie He Za Zhi 2001 21 684 687
    • (2001) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.21 , pp. 684-687
    • Li, X.R.1    Zhang, D.2    Qi, Y.F.3
  • 84
    • 41649104522 scopus 로고    scopus 로고
    • Screening of QHF formula for effective ingredients from Chinese herbs and its anti-hepatic cell cancer effect in combination with chemotherapy
    • Chen T., Li D., Fu Y. L., Hu W., Screening of QHF formula for effective ingredients from Chinese herbs and its anti-hepatic cell cancer effect in combination with chemotherapy Chinese Medical Journal 2008 20 121 363 368 (Pubitemid 351479655)
    • (2008) Chinese Medical Journal , vol.121 , Issue.4 , pp. 363-368
    • Chen, T.1    Li, D.2    Fu, Y.-L.3    Hu, W.4
  • 85
    • 39849099528 scopus 로고    scopus 로고
    • Expression of phosphatase and tensin homolog deleted on chromosome ten in liver of athymic mice with hepatocellular carcinoma and the effect of Fuzheng Jiedu Decoction
    • Yin L. R., Chen Z. X., Zhang S. J., Sun B. G., Liu Y. D., Huang H. Z., Expression of phosphatase and tensin homolog deleted on chromosome ten in liver of athymic mice with hepatocellular carcinoma and the effect of Fuzheng Jiedu Decoction World Journal of Gastroenterology 2008 14 108 113
    • (2008) World Journal of Gastroenterology , vol.14 , pp. 108-113
    • Yin, L.R.1    Chen, Z.X.2    Zhang, S.J.3    Sun, B.G.4    Liu, Y.D.5    Huang, H.Z.6
  • 87
    • 57349182163 scopus 로고    scopus 로고
    • Protective effect of Juzen-taiho-to on hepatocarcinogenesis is mediated through the inhibition of Kupffer cell-induced oxidative stress
    • Tsuchiya M., Kono H., Matsuda M., Fujii H., Rusyn I., Protective effect of Juzen-taiho-to on hepatocarcinogenesis is mediated through the inhibition of Kupffer cell-induced oxidative stress International Journal of Cancer 2008 123 11 2503 2511
    • (2008) International Journal of Cancer , vol.123 , Issue.11 , pp. 2503-2511
    • Tsuchiya, M.1    Kono, H.2    Matsuda, M.3    Fujii, H.4    Rusyn, I.5
  • 88
    • 0024315666 scopus 로고
    • Controlled prospective trial to evaluate Syo-saiko-to for the prevention of hepatocellular carcinoma in patients with cirrhosis of the liver
    • Yamamoto S., Oka H., Kanno T., Mizoguchi Y., Kobayashi K., Controlled prospective trial to evaluate Syosakiko-to in preventing hepatocellular carcinoma in patients with cirrhosis of the liver Gan To Kagaku Ryoho 1989 16 4, part 2 1519 1524 (Pubitemid 19189483)
    • (1989) Japanese Journal of Cancer and Chemotherapy , vol.16 , Issue.4 , pp. 1519-1524
    • Yamamoto, S.1    Oka, H.2    Kanno, T.3    Mizoguchi, Y.4    Kobayashi, K.5
  • 90
    • 23844454022 scopus 로고    scopus 로고
    • Chinese herbal medicine and chemotherapy in the treatment of hepatocellular carcinoma: A meta-analysis of randomized controlled trials
    • DOI 10.1177/1534735405279927
    • Shu X., McCulloch M., Xiao H., Broffman M., Gao J., Chinese herbal medicine and chemotherapy in the treatment of hepatocellular carcinoma: a meta-analysis of randomized controlled trials Integrative Cancer Therapies 2005 4 3 219 229 (Pubitemid 41153748)
    • (2005) Integrative Cancer Therapies , vol.4 , Issue.3 , pp. 219-229
    • Shu, X.1    McCulloch, M.2    Xiao, H.3    Broffman, M.4    Gao, J.5
  • 91
    • 34547629947 scopus 로고    scopus 로고
    • Clinical study of method of strengthening body resistance and disintoxication disintoxication in patients with HCC of post-TACE
    • Chen Z. X., Zhang S. J., Hu H. T., Sun B. G., Yin L. R., [Clinical study of method of strengthening body resistance and disintoxication disintoxication in patients with HCC of post-TACE] Zhongguo Zhong Yao Za Zhi 2007 32 1211 1213
    • (2007) Zhongguo Zhong Yao Za Zhi , vol.32 , pp. 1211-1213
    • Chen, Z.X.1    Zhang, S.J.2    Hu, H.T.3    Sun, B.G.4    Yin, L.R.5
  • 92
    • 33747516825 scopus 로고    scopus 로고
    • Hot water-extracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells
    • Chao J. C.-J., Chiang S.-W., Wang C.-C., Tsai Y.-H., Wu M.-S., Hot water-extracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells World Journal of Gastroenterology 2006 12 28 4478 4484 (Pubitemid 44256333)
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.28 , pp. 4478-4484
    • Chao, J.C.-J.1    Chiang, S.-W.2    Wang, C.-C.3    Tsai, Y.-H.4    Wu, M.-S.5
  • 93
    • 21744451362 scopus 로고    scopus 로고
    • Chemoprevention against hepatocellular carcinoma of Cornus officinalis in vitro
    • DOI 10.1142/S0192415X04002296, PII S0192415X04002296
    • Chang J.-S., Chiang L.-C., Hsu F.-F., Lin C.-C., Chemoprevention against hepatocellular carcinoma of Cornus officinalis in vitro American Journal of Chinese Medicine 2004 32 5 717 725 (Pubitemid 41435128)
    • (2004) American Journal of Chinese Medicine , vol.32 , Issue.5 , pp. 717-725
    • Chang, J.-S.1    Chiang, L.-C.2    Hsu, F.-F.3    Lin, C.-C.4
  • 94
    • 0029879715 scopus 로고    scopus 로고
    • Herbal medicine 'Sho-saiko-to' induces tumour necrosis factor-α and granulocyte colony-stimulating factor in vitro in peripheral blood mononuclear cells of patients with hepatocellular carcinoma
    • Yamashiki M., Nishimura A., Nomoto M., Suzuki H., Kosaka Y., Herbal medicine 'Sho-saiko-to' induces tumour necrosis factor- and granulocyte colony-stimulating factor in vitro in peripheral blood mononuclear cells of patients with hepatocellular carcinoma Journal of Gastroenterology and Hepatology 1996 11 2 137 142 (Pubitemid 26122452)
    • (1996) Journal of Gastroenterology and Hepatology , vol.11 , Issue.2 , pp. 137-142
    • Yamashiki, M.1    Nishimura, A.2    Nomoto, M.3    Suzuki, H.4    Kosaka, Y.5
  • 95
    • 34548018350 scopus 로고    scopus 로고
    • The application of Bletilla striata in the interventional therapy of hepatocellular carcinoma: A comparative study using ACI rats
    • Qian J., Zheng Z. S., Wu H. P., Li W. Y., Vossoughi D., Elsie O., Thomas V., Feng G. S., The application of Bletilla striata in the interventional therapy of hepatocellular carcinoma: a comparative study using ACI rats Zhonghua Gan Zang Bing Za Zhi 2005 13 2 143 144
    • (2005) Zhonghua Gan Zang Bing Za Zhi , vol.13 , Issue.2 , pp. 143-144
    • Qian, J.1    Zheng, Z.S.2    Wu, H.P.3    Li, W.Y.4    Vossoughi, D.5    Elsie, O.6    Thomas, V.7    Feng, G.S.8


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