Development of drug-loaded PLGA microparticles with different release patterns for prolonged drug delivery

Bulletin of the Korean Chemical Society

Volumn 32, Issue 3, 2011, Pages 867-872

  Choi, Yeonsoon ^a   Joo, Jae Ryang ^a   Hong, Areum ^a   Park, Jong Sang ^a  

^a Seoul National University   (South Korea)

Author keywords

Biodegradable polymers; Drug delivery system; PLGA microparticles; Solvent evaporation method

Indexed keywords

CONCENTRATION GRADIENTS; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG LOADING; DRUG-RELEASE RATE; ENCAPSULATION EFFICIENCY; IN-VITRO; LOW MOLECULAR WEIGHT DRUGS; MICRO-PARTICLES; PLGA MICROPARTICLES; POLY(LACTIC-CO-GLYCOLIC ACID); RELEASE PATTERN; RELEASE PROFILES; SLOW RELEASE; SOLVENT EVAPORATION METHOD; SUSTAINED RELEASE;

DRUG DELIVERY; DRUG PRODUCTS; EMULSIFICATION; ENCAPSULATION; EVAPORATION; PHASE TRANSITIONS;

BIODEGRADABLE POLYMERS;

EID: 79953252159     PISSN: 02532964     EISSN: 12295949     Source Type: Journal    
DOI: 10.5012/bkcs.2011.32.3.867     Document Type: Article

References (11)

1. Choi, H. S.; Seo, S. A.; Khang, G.; Rhee, J. M.; Lee, H. B. Int. J. Pharm. 2002, 234, 195.
2. Xie, S.; Wang, S.; Zhu, L.; Wang, F.; Zhour, W. Colloid. Surface B 2009, 74, 358.
3. Lee, W. K.; Park, J. Y.; Yang, E. H.; Suh, H.; Kim, S. H.; Chung, D. S.; Choi, K.; Yang, C. W.; Park, J. S. J. Control. Release 2002, 84, 115.
4. Berkland, C.; Kim, K.; Pack, D. W. J. Control. Release 2001, 73, 59.
5. Govender, T.; Stolnik, S.; Garnett, M. C.; Illum, L.; Davis, S. S. J. Control. Release 1999, 57, 171.
6. Ye, M.; Kim, S.; Park, K. J. Control. Release 2010, 146, 241.
7. Freitas, S.; Merkle, H. P.; Gander, B. J. Control. Release 2005, 102, 313.
8. Katou, H.; Wandrey, A. J.; Gander, B. Int. J. Pharm. 2008, 364, 45.
9. Yeo, Y.; Park, K. Arch. Pharm. Res. 2004, 27, 1.
10. Yang, Y.; Chung, T.; Ng, N. P. Biomaterials 2001, 22, 231.
11. Berkland, C.; King, M.; Cox, A.; Kim, K.; Pack, D. W. J. Control. Release 2002, 82, 137.