Gene copy number variations: It is important to determine which allele is affected

Pharmacogenomics

Volumn 12, Issue 3, 2011, Pages 299-301

  Ramamoorthy, Anuradha ^a   Skaar, Todd C ^b  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

copy number variations; drug metabolizing enzymes; pharmacogenetics

Indexed keywords

ANTIARRHYTHMIC AGENT; ANTIDEPRESSANT AGENT; ANTIHYPERTENSIVE AGENT; CYTOCHROME P450 2D6; DEXTROMETHORPHAN; NEUROLEPTIC AGENT; OPIATE;

ALLELE; COPY NUMBER VARIATION; CYP2D6 GENE; DRUG METABOLISM; ENZYME ACTIVITY; GENE; GENE DELETION; GENE FREQUENCY; GENE FUNCTION; GENOTYPE PHENOTYPE CORRELATION; HETEROZYGOTE; HUMAN; HUMAN GENOME; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; CYTOCHROME P-450 CYP2D6; DEXTROMETHORPHAN; DNA COPY NUMBER VARIATIONS; GENE AMPLIFICATION; GENE DELETION; GENE DOSAGE; GENETIC ASSOCIATION STUDIES; HUMANS; METABOLIC DETOXICATION, DRUG; PHENOTYPE;

EID: 79953249419     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.11.5     Document Type: Review

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