-
1
-
-
13244298981
-
Potential role of drug transporters in the pathogenesis of medically intractable epilepsy
-
DOI 10.1111/j.0013-9580.2005.31904.x
-
Kwan P, Brodie MJ: Potential role of drug transporters In the pathogenesis of medically intractable epilepsy. Epilepsia 46, 224-235 (2005). (Pubitemid 40194666)
-
(2005)
Epilepsia
, vol.46
, Issue.2
, pp. 224-235
-
-
Kwan, P.1
Brodie, M.J.2
-
2
-
-
33846504706
-
A 'silent' polymorphism in the MDR1 gene changes substrate specificity
-
DOI 10.1126/science.1135308
-
Kimchi-Sarfaty C, OhJM, Kim L-W, et al. A 'silent' polymorphism in the MDRl gene changes substrate specificity. Science 315, 525-528 (2007). (Pubitemid 46175758)
-
(2007)
Science
, vol.315
, Issue.5811
, pp. 525-528
-
-
Kimchi-Sarfaty, C.1
Oh, J.M.2
Kim, I.-W.3
Sauna, Z.E.4
Calcagno, A.M.5
Ambudkar, S.V.6
Gottesman, M.M.7
-
3
-
-
77955325040
-
ABCBl C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: A systematic review and meta-analysis
-
Haerian BS, Roslan H, RaymondAA et al. ABCBl C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis. Seizure 19,339-346(2010).
-
(2010)
Seizure
, vol.19
, pp. 339-346
-
-
Haerian, B.S.1
Roslan, H.2
Raymond, A.A.3
-
4
-
-
0242490855
-
Major Vault Protein, a Marker of Drug Resistance, Is Upregulated in Refractory Epilepsy
-
DOI 10.1046/j.1528-1157.2003.21803.x
-
Sisodiya SM, Martinian L, Scheffer GL et al. Major vault protein, a marker of drug resistance, is upregulated in refractory epilepsy. Epilepsia 44, 1388-1396 (2003). (Pubitemid 37385846)
-
(2003)
Epilepsia
, vol.44
, Issue.11
, pp. 1388-1396
-
-
Sisodiya, S.M.1
Martinian, L.2
Scheffer, G.L.3
Van der Valk, P.4
Cross, J.H.5
Scheper, R.J.6
Harding, B.N.7
Thom, M.8
-
5
-
-
20544436363
-
Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain
-
Aronica E, Gorter JA, Redeker S et al.: Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain. Epilepsia 46, 849-857 (2003).
-
(2003)
Epilepsia
, vol.46
, pp. 849-857
-
-
Aronica, E.1
Gorter, J.A.2
Redeker, S.3
-
6
-
-
33644503533
-
Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis
-
Kutoba H, Ishihara H, Langmann T et al. Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis. Epilepsy Res. 68, 213-228(2006).
-
(2006)
Epilepsy Res.
, vol.68
, pp. 213-228
-
-
Kutoba, H.1
Ishihara, H.2
Langmann, T.3
-
7
-
-
0037665280
-
Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity
-
DOI 10.1124/jpet.103.049858
-
Potschka H, Fedrowitz M, Loscher W: Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity. Pharmacol. Exp. Ther. 306, 124-131 (2003). (Pubitemid 36734365)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.306
, Issue.1
, pp. 124-131
-
-
Potschka, H.1
Fedrowitz, M.2
Loscher, W.3
-
8
-
-
42549099018
-
ABCC2 haplotype is not associated with drug-resistant epilepsy
-
DOI 10.1211/jpp.60.5.0009
-
Seo T, Ishitsu T, Oniki K, Abe T, Shuto T, Nakagawa K: ABCC2 haplotype is not associated with drug-resistant epilepsy. Pharm. Pharmacol. 60, 631-635 (2008). (Pubitemid 351589051)
-
(2008)
Journal of Pharmacy and Pharmacology
, vol.60
, Issue.5
, pp. 631-635
-
-
Seo, T.1
Ishitsu, T.2
Oniki, K.3
Abe, T.4
Shuto, T.5
Nakagawa, K.6
-
9
-
-
60949100347
-
> and ABCC2 genetic polymorphisms and multidrug resistance in partial epilepsy
-
> and ABCC2 genetic polymorphisms and multidrug resistance in partial epilepsy. Epilepsy Res. 84, 86-90 (2009).
-
(2009)
Epilepsy Res.
, vol.84
, pp. 86-90
-
-
Kim, D.1
Lee, S.K.2
Chu, K.3
-
10
-
-
67149124051
-
Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy
-
UferM, Mosyagin I, Muhle H et al.: Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy. Pharmacogenet. Genomics 19, 353-362 (2009).
-
(2009)
Pharmacogenet. Genomics
, vol.19
, pp. 353-362
-
-
Ufer, M.1
Mosyagin, I.2
Muhle, H.3
-
11
-
-
34447619872
-
Association between ABCB1 C3435T polymorphism and drug-resistant epilepsy in Han Chinese
-
DOI 10.1016/j.yebeh.2007.04.013, PII S1525505007001540
-
Kwan P, Baum L, Wong V et al.: Association between ABCBl C3435T polymorphism and drug-resistant epilepsy in Han Chinese. Epilepsy Behav. 11, 112-117(2007). (Pubitemid 47087203)
-
(2007)
Epilepsy and Behavior
, vol.11
, Issue.1
, pp. 112-117
-
-
Kwan, P.1
Baum, L.2
Wong, V.3
Ng, P.W.4
Lui, C.H.5
Sin, N.C.6
Hui, A.C.F.7
Yu, E.8
Wong, L.K.S.9
-
12
-
-
77954625557
-
Definition of drug-resistant epilepsy Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies
-
Kwan P, Arzimanoglou A, Berg AT et al.: Definition of drug-resistant epilepsy Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia 51, 1069-1077 (2010).
-
(2010)
Epilepsia
, vol.51
, pp. 1069-1077
-
-
Kwan, P.1
Arzimanoglou, A.2
Berg, A.T.3
-
13
-
-
66849129225
-
Gene-wide tagging study of association between ABCBl polymorphisms and multidrug resistance in epilepsy in Han Chinese
-
Kwan P, Wong V, Ng PW et al.: Gene-wide tagging study of association between ABCBl polymorphisms and multidrug resistance in epilepsy in Han Chinese. Pharmacogenomics 10,723-732 (2009).
-
(2009)
Pharmacogenomics
, vol.10
, pp. 723-732
-
-
Kwan, P.1
Wong, V.2
Ng, P.W.3
-
14
-
-
76349096470
-
Genetic factors associated with drug-resistance of epilepsy: Relevance of stratification by patient age and aetiology of epilepsy
-
Sanchez MB, Herranz JL, Leno C et al. Genetic factors associated with drug-resistance of epilepsy: relevance of stratification by patient age and aetiology of epilepsy. Seizure 19, 93-101 (2010).
-
(2010)
Seizure
, vol.19
, pp. 93-101
-
-
Sanchez, M.B.1
Herranz, J.L.2
Leno, C.3
-
15
-
-
33846271368
-
Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein
-
DOI 10.1016/j.neuropharm.2006.07.038, PII S002839080600270X
-
Bakes S, Gastens AM, Fedrowitz M, Potschka H, Kaever V, Loscher W: Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein. Neuropharmacology 52, 333-346(2007). (Pubitemid 46123353)
-
(2007)
Neuropharmacology
, vol.52
, Issue.2
, pp. 333-346
-
-
Baltes, S.1
Gastens, A.M.2
Fedrowitz, M.3
Potschka, H.4
Kaever, V.5
Loscher, W.6
-
16
-
-
0347364703
-
- Rats
-
DOI 10.1111/j.0013-9580.2003.22603.x
-
Potschka H, Fedrowitz M, Loscher W: Brain access and anticonvulsant efficacy of carbamazepine, lamotrigine, and felbamate in 5CC2/MRP2-deficient TR-rats. Epilepsia 44, 1479-1486 (2003). (Pubitemid 38020180)
-
(2003)
Epilepsia
, vol.44
, Issue.12
, pp. 1479-1486
-
-
Potschka, H.1
Fedrowitz, M.2
Loscher, W.3
-
17
-
-
77950949013
-
Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRPl, 2 and 5) that are overexpressed in pharmacoresistant epilepsy
-
Luna-Tortos C, Fedrowitz M, Loscher W: Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRPl, 2 and 5) that are overexpressed in pharmacoresistant epilepsy. Neuropharmacology 58, 1019-1032 (2010).
-
(2010)
Neuropharmacology
, vol.58
, pp. 1019-1032
-
-
Luna-Tortos, C.1
Fedrowitz, M.2
Loscher, W.3
-
18
-
-
33644810414
-
Lack of interactions between breast cancer resistance protein (BCRP/ABCG2) and selected antiepileptic agents
-
DOI 10.1111/j.1528-1167.2006.00453.x
-
Cerveny L, Pavek P, Malakova J, Staud F, Fendrich Z: Lack of interactions between breast cancer resistance protein (bcrp/abcg2) and selected antiepileptic agents. Epilepsia 47, 461-468 (2006). (Pubitemid 43351546)
-
(2006)
Epilepsia
, vol.47
, Issue.3
, pp. 461-468
-
-
Cerveny, L.1
Pavek, P.2
Malakova, J.3
Staud, F.4
Fendrich, Z.5
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