Detection of leukotriene receptor cysLT1r in inflammatory diseases by molecular imaging with near-infrared fluorescence-based contrast agents

Molecular Imaging

Volumn 10, Issue 2, 2011, Pages 81-90

  Busch, Corinna ^a   Passon, Marta ^a   Wenzel, Matthias ^a   Socher, Ines ^a   Kaiser, Werner A ^a   Hilger, Ingrid ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIODISTRIBUTIONS; CONTRAST AGENT; DIAGNOSTIC TOOLS; EARLY DIAGNOSIS; FAB FRAGMENTS; FLUORESCENCE INTENSITIES; HEMICYANINE; HL-60 CELLS; IN-VITRO; IN-VIVO; INFLAMMATORY DISEASE; INFLAMMATORY PROCESS; LONG TERM; MOLECULAR IMAGING; NEAR INFRA RED; NEAR-INFRARED FLUORESCENCE; PROMYELOCYTIC LEUKEMIA; REAL-TIME PCR; REVERSE TRANSCRIPTASE- POLYMERASE CHAIN REACTION; SEMI-QUANTITATIVE ANALYSIS; SPECIFIC DETECTION; UP-REGULATION; WHOLE-BODY IMAGING;

ANTIBODIES; DIAGNOSIS; DISEASES; FLOW CYTOMETRY; FLUOROPHORES; INFRARED DEVICES; LIVER; PROBES;

POLYMERASE CHAIN REACTION;

CONTRAST MEDIUM; DIAGNOSTIC AGENT; FLUORESCENT DYE; IMMUNOGLOBULIN G; LEUKOTRIENE D4 RECEPTOR; LEUKOTRIENE RECEPTOR;

ANIMAL; ARTICLE; CELL STRAIN HL 60; CHEMISTRY; EDEMA; FLUORESCENCE; HUMAN; IMMUNOLOGY; INFLAMMATION; INFRARED RADIATION; MALE; METABOLISM; METHODOLOGY; MOLECULAR IMAGING; MOUSE; PATHOLOGY; RABBIT; TISSUE DISTRIBUTION;

ANIMALS; CONTRAST MEDIA; EDEMA; FLUORESCENCE; FLUORESCENT DYES; HL-60 CELLS; HUMANS; IMMUNOGLOBULIN G; INFLAMMATION; INFRARED RAYS; MALE; MICE; MOLECULAR IMAGING; RABBITS; RECEPTORS, LEUKOTRIENE; TISSUE DISTRIBUTION;

EID: 79953232998     PISSN: 15353508     EISSN: None     Source Type: Journal    
DOI: 10.2310/7290.2010.00023     Document Type: Article

References (29)

1. Weissleder R, Mahmood U. Molecular imaging. Radiology 2001; 219:316-33. (Pubitemid 32336342)
2. Ntziachristos V, Ripoll J, Wang L, Weissleder R. Looking and listening to light: The evolution of whole-body photonic imaging. Nat Biotechnol 2005;23:313-20. (Pubitemid 41094419)
3. Weissleder R, Tung C, Mahmood U, Bogdanov AJ. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol 1999;17:375-8. (Pubitemid 29166041)
4. Becker A, Hessenius C, Licha K, et al. Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands. Nat Biotechnol 2001;19:327-31. (Pubitemid 32275340)
5. Hansch A, Frey O, Hilger I, et al. Diagnosis of arthritis using nearinfrared fluorochrome Cy5.5. Invest Radiol 2004;39:626-32. (Pubitemid 39287603)
6. Hansch A, Frey O, Sauner D, et al. In vivo imaging of experimental arthritis with near-infrared fluorescence (NIRF). Arthritis Rheum 2004;50:961-7. (Pubitemid 38326197)
7. Cohen J. The immunopathogenesis of sepsis. Nature 2002;420: 885-91. (Pubitemid 36019643)
8. Libby P. Inflammation in atherosclerosis. Nature 2002;420:868-74. (Pubitemid 36019640)
9. Borgeat P, Samuelsson B. Arachidonic acid metabolism in polymorphonuclear leukocytes: Unstable intermediate in formation of dihydroxy acids. Proc Natl Acad Sci U S A 1979;76:3213-7. (Pubitemid 9233259)
10. Metters K. Leukotriene receptors. J Lipid Mediat Cell Signal 1995; 12:413-27.
11. Lynch K, O'Neill G, Liu Q, et al. Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature 1999;399:789-93. (Pubitemid 29293175)
12. Sarau H, Ames R, Chambers J, et al. Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor. Mol Pharmacol 1999;56:657-3.
13. Brooks C, Summers J. Modulators of leukotriene biosynthesis and receptor activation. J Med Chem 1996;39:2629-54. (Pubitemid 26240330)
14. Davidson A, Lee T, Scanlon P, et al. Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects. Am Rev Respir Dis 1987;135:333-7. (Pubitemid 17012091)
15. Kurnatowska I, Pawlikowski M. Anti-inflammatory effects of somatostatin analogs on zymosan-induced earlobe inflammation in mice: Comparison with dexamethasone and ketoprofen. Neuroimmunomodulation 2001;9:119-24. (Pubitemid 34042863)
16. Hui Y, Funk C. Cysteinyl leukotriene receptors. Biochem Pharmacol 2002;64:1549-57. (Pubitemid 35339376)
17. Licha K. Contrast agents for optical imaging. Top Curr Chem 2002;222:1-29.
18. Resch-Genger U, Grabolle M, Cavaliere-Jaricot S, et al. Quantum dots versus organic dyes as fluorescent labels. Nat Methods 2008;5: 763-75.
19. Pauli J, Vag T, Haag R, et al. An in vitro characterization study of new near infrared dyes for molecular imaging. Eur J Med Chem 2009;44:3496-503.
20. Thivierge M, Doty M, Johnson J, et al. IL-5 up-regulates cysteinyl leukotriene 1 receptor expression in HL-60 cells differentiated into eosinophils. J Immunol 2000;165:5221-6.
21. Blair O, Carbone R, Sartorelli A. Differentiation of HL-60 promyelocytic leukemia cells: Simultaneous determination of phagocytic activity and cell cycle distribution by flow cytometry. Cytometry 1986;7:171-7. (Pubitemid 16166684)
22. Rovera G, Santoli D, Damsky C. Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester. Proc Natl Acad Sci U S A 1979;76:2779-83. (Pubitemid 9213164)
23. Swirski F, Nahrendorf M, Etzrodt M, et al. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 2009;325:612-6.
24. Erdö F, Török K, Arányi P, Székely J. A new assay for antiphlogistic activity: Zymosan-induced mouse ear inflammation. Agents Actions 1993;39:137-42. (Pubitemid 23349822)
25. Deissler V, Rüger R, Frank W, et al. Fluorescent liposomes as contrast agents for in vivo optical imaging of edemas in mice. Small 2008;4:1240-6.
26. Zuckier L, Rodriguez L, Scharff M. Immunologic and pharmacologic concepts of monoclonal antibodies. Semin Nucl Med 1989; 19:166-86.
27. Covell D, Barbet J, Holton O, et al. Pharmacokinetics of monoclonal immunoglobulin G1, F(ab9)2, and Fab9 in mice. Cancer Res 1986;46:3969-78. (Pubitemid 16075893)
28. Klohs J, Grafe M, Graf K, et al. In vivo imaging of the inflammatory receptor CD40 after cerebral ischemia using a fluorescent antibody. Stroke 2008;39:2845-52.
29. Eisenblätter M, Ehrchen J, Varga G, et al. In vivo optical imaging of cellular inflammatory response in granuloma formation using fluorescence-labeled macrophages. J Nucl Med 2009;50:1676-82.