Per-N-methylated analogues of an antitumor bicyclic hexapeptide RA-VII

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 7, 2011, Pages 2458-2463

  Hitotsuyanagi, Yukio ^a   Lee, Ji Ean ^a   Kato, Saori ^a   Kim, Ik Hwi ^a   Kohashi, Hideyuki ^a   Fukaya, Haruhiko ^a   Takeya, Koichi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Bouvardin; Cytotoxicity; N Methylation; RA VII; Rubia cordifolia; X ray crystallography

Indexed keywords

ALANINE; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; HEXAPEPTIDE; HEXAPEPTIDE RA VII; METHYL GROUP; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL STRAIN; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; LEUKEMIA CELL; METHYLATION; NONHUMAN; TUMOR CELL P 388;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CRYSTALLOGRAPHY, X-RAY; HUMANS; LEUKEMIA P388; MICE; MOLECULAR CONFORMATION; OLIGOPEPTIDES; PEPTIDES, CYCLIC; RUBIA;

RUBIA CORDIFOLIA;

EID: 79953231163     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.02.003     Document Type: Article

References (19)

1. H. Itokawa, K. Takeya, K. Mihara, N. Mori, T. Hamanaka, T. Sonobe, and Y. Iitaka Chem. Pharm. Bull. 31 1983 1424
2. H. Itokawa, K. Takeya, Y. Hitotsuyanagi, and H. Morita G.A. Cordell, The Alkaloids Vol. 49 1997 Academic Press NY 301
3. S.D. Jolad, J.J. Hoffman, S.J. Torrance, R.M. Wiedhopf, J.R. Cole, S.K. Arora, R.B. Bates, R.L. Gargiulo, and G.R. Kriek J. Am. Chem. Soc. 99 1977 8040
4. M. Zalacaín, E. Zaera, D. Vázquez, and A. Jiménez FEBS Lett. 148 1982 95
5. B.V. Sirdeshpande, and P.L. Toogood Bioorg. Chem. 23 1995 460
6. H. Fujiwara, S. Saito, Y. Hitotsuyanagi, K. Takeya, and Y. Ohizumi Cancer Lett. 209 2004 223
7. R.B. Bates, J.R. Cole, J.J. Hoffmann, G.R. Kriek, G.S. Linz, and S.J. Torrance J. Am. Chem. Soc. 105 1983 1343
8. H. Morita, K. Kondo, Y. Hitotsuyanagi, K. Takeya, H. Itokawa, N. Tomioka, A. Itai, and Y. Iitaka Tetrahedron 47 1991 2757
9. H. Itokawa, K. Kondo, Y. Hitotsuyanagi, M. Isomura, and K. Takeya Chem. Pharm. Bull. 41 1993 1402
10. H. Itokawa, K. Saitou, H. Morita, K. Takeya, and K. Yamada Chem. Pharm. Bull. 40 1992 2984
11. D.L. Boger, and J. Zhou J. Am. Chem. Soc. 117 1995 7364
12. Y. Hitotsuyanagi, J. Suzuki, K. Takeya, and H. Itokawa Bioorg. Med. Chem. Lett. 4 1994 1633
13. P. Gund, and D.F. Veber J. Am. Chem. Soc. 101 1979 1885
14. H. Itokawa, H. Morita, K. Kondo, Y. Hitotsuyanagi, K. Takeya, and Y. Iitaka J. Chem. Soc., Perkin Trans. 2 1992 1635
15. Y. Hitotsuyanagi, S.-i. Sasaki, Y. Matsumoto, K. Yamaguchi, H. Itokawa, and K. Takeya J. Am. Chem. Soc. 125 2003 7284
16. H. Itokawa, K. Takeya, N. Mori, T. Sonobe, S. Mihashi, and T. Hamanaka Chem. Pharm. Bull. 34 1986 3762
17. H. Itokawa, K. Kondo, Y. Hitotsuyanagi, A. Nakamura, H. Morita, and K. Takeya Chem. Pharm. Bull. 41 1993 1266
18. G.M. Sheldrick shelxs-97: Program for the Solution of Crystal Structures 1997 University of Göttingen Göttingen, Germany
19. G.M. Sheldrick shelxl-97: Program for the Refinement of Crystal Structures 1997 University of Göttingen Göttingen, Germany