Chapter 4 Macrocyclic Peptide Alkaloids From Plants

Alkaloids: Chemistry and Pharmacology

Volumn 49, Issue C, 1997, Pages 301-387

  Itokawa, Hideji ^a   Takeya, Koichi ^a   Hitotsuyanagi, Yukio ^a   Morita, Hiroshi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956831525     PISSN: 00999598     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0099-9598(08)60018-8     Document Type: Article

References (348)

1. Itokawa H., Takeya K., and Mihashi S. Jpn. J. Pharmacog. 33 (1979) 95
2. Itokawa H., Takeya K., Watanabe K., and Mihara K. Jpn. J. Pharmacog. 36 (1982) 145
3. Itokawa H., Hirayama F., Tsuruoka S., Mizuno K., Takeya K., and Nitta A. Jpn. J. Pharmacog. 44 (1990) 58
4. Hirobe C., Palevitch D., Takeya K., and Itokawa H. Nat. Med. 48 (1994) 168
5. Itokawa H. "Discovery of new antitumor agents from medicinal plants,". "Pharmacy World Congress '91, Washington, DC, Proc. Topics in Pharmaceutical Sciences" (1991) 607-630
6. Itokawa H., and Takeya K. Heterocycles 35 (1993) 1467
7. Tschesche R., and Kaussmann E.U. The Alkaloids 15 (1975) 165
8. Schmidt U., Lieberkneckt A., and Haslinger E. The Alkaloids 26 (1985) 299
9. Greger H. Planta Med. 50 (1984) 366
10. Joullié M.M., and Nutt R.F. In: Pelletier S.W. (Ed). "Alkaloids, Chemical and Biological Perspectives" 3 (1985), Wiley Interscience, New York 113
11. Shah A.H., and Panday V.B. J. Chem. Soc. Pak. 7 (1985) 363
12. Chem. Abstr. 105 (1986) 170627
13. Winkelmann G., Berner I., and Huschka H.G. J. Plant Nutr. 11 (1988) 883
14. Chem. Abstr. 110 (1989) 36550
15. Schmidt H. Nachr. Chem. Teach. Lab. 37 (1989) 1034
16. Chem. Abstr. 112 (1990) 36394
17. Lewis J.R. Nat. Prod. Rep. 2 (1985) 245
18. Nat. Prod. Rep. 3 (1986) 587
19. Nat. Prod. Rep. 5 (1988) 351
20. Nat. Prod. Rep. 6 (1989) 503
21. Nat. Prod. Rep. 7 (1990) 365
22. Nat. Prod. Rep. 8 (1991) 171
23. Nat. Prod. Rep. 9 (1992) 81
24. Nat. Prod. Rep. 10 (1993) 29
25. Nat. Prod. Rep. 11 (1994) 395
26. Nat. Prod. Rep. 12 (1995) 135
27. Nat. Prod. Rep. 13 (1996) 435
28. Shah A.H., Pandey V.B., Eckhardt G., and Tschesche R. Phytochemistry 23 (1984) 931
29. Shah A.H., Pandey V.B., Eckhardt G., and Tschesche R. Phytochemistry 24 (1985) 2765
30. Shah A.H., Pandey V.B., Eckhardt G., and Tschesche R. J. Nat. Prod. 48 (1985) 555
31. Shah A.H., Pandey V.B., Eckhardt G., and Tschesche R. Phytochemistry 24 (1985) 2768
32. Shah A.H., Pandey V.B., Singh J.P., Singh K.N., and Eckhardt G. Phytochemistry 23 (1984) 2120
33. Shah A.H., Miana G.A., Devi S., and Pandey V.B. Planta Med. (1987) 500
34. Shah A.H., Al-Yahya M.A., Devi S., and Pandey V.B. Phytochemistry 26 (1987) 1230
35. Shah A.H., Pandey V.B., Eckhardt G., and Miana G.A. Heterocycles 27 (1988) 2777
36. Pandey V.B., Singh J.P., Seth K.K., Shah A.H., and Eckhardt G. Phytochemistry 23 (1984) 2118
37. Pandey V.B., Dwivedi S.P.D., Shah A.H., and Eckhardt G. Phytochemistry 25 (1986) 2690
38. Miana G.A., and Shah A.H. Fitoterapia 56 (1985) 363
39. Chem. Abstr. 105 (1986) 75886
40. Dwivedi S.P.D., Pandey V.B., Shah A.H., and Eckhardt G. J. Nat. Prod. 50 (1987) 235
41. Devi S., Pandey V.B., Singh J.P., and Shah A.H. Phytochemistry 26 (1987) 3374
42. Shah A.H., and Pandey V.B. Proc. Pak. Acad. Sci. 26 (1989) 227
43. Chem. Abstr. 114 (1991) 43273
44. Shah A.H., Khan R.M.A., Maurya S.K., and Singh V.P. Phytochemistry 28 (1989) 305
45. Singh B., and Pandey V.B. Phytochemistry 38 (1995) 271
46. Heffner R.J., Jiang J., and Joullie M.M. J. Am. Chem. Soc. 114 (1992) 10181
47. Pandey V.D., Devi S., Singh J.P., and Shah A.H. J. Nat. Prod. 49 (1986) 939
48. Han B.H., Park M.H., and Park J.H. Saenzyak Hakloechi 16 (1986) 233
49. Chem. Abstr. 107 (1987) 102502
50. Han B.H., and Park M.H. Arch. Pharmacol Res. 10 (1987) 208
51. Chem. Abstr. 109 (1988) 66702
52. Han B., Park H., and Park J.H. Pure Appl. Chem. 61 (1989) 443
53. Chem. Abstr. 111 (1989) 167135
54. Han B.H., Park M.H., and Han Y.N. Yakhak Hoechi 37 (1993) 143
55. Chem. Abstr. 119 (1993) 210390
56. Khokhar I., and Ahmad A. Pak. J. Sci. 43 (1991) 108
57. Chem. Abstr. 119 (1993) 45225
58. Khokhar I., and Ahmad A. Pak. J. Sci. 44 (1992) 37
59. Chem. Abstr. 121 (1994) 297131
60. J. Nat. Sci. Math. 34 (1994) 159
61. Chem. Abstr. 123 (1995) 29540
62. Pandey V.B., Tripathi Y.C., Devi S., Singh J.P., and Shah A.H. Phytochemistry 27 (1988) 1915
63. Tripathi Y.C., Maurya S.K., Singh V.P., and Pandey V.B. Phytochemistry 28 (1989) 1563
64. Han B.H., Park M.H., and Han Y.N. Phytochemistry 29 (1990) 3315
65. Han B.H., Han Y.N., Park M.H., Park J.I., and Park M.K. Saenghwahaku Nyusu 10 (1990) 239
66. Chem. Abstr. 115 (1991) 15368
67. Abdel-Galil F.M., and El-Jissly M.A. Phytochemistry 30 (1991) 1348
68. Shah A.H., Al-Yahya M.A., Al-Sayed A.M., Tariq M., and Ageel A.M. Pak. J. Pharm. 2 (1989) 81
69. Chem. Abstr. 115 (1991) 9096
70. Shah A.H., Ageel A., Tariq M., Mossa J.S., and Al-Yahya M.A. Fitoterapia 57 (1986) 452
71. Chem. Abstr. 107 (1987) 151190
72. Ohedira K., Chemli R., Richard B., Nuzillard J.-M., Zeches M., and Men-Oliver L.L. Phytochemistry 32 (1993) 1591
73. Abu-Zarga M., Sabri S., Al-Aboudi A., Ajaz M.S., Sultana N., and Atta-ur-Rahman. J. Nat. Prod. 58 (1995) 504
74. Ghedira K., Chemli R., Caron C., Nuzillard J.-M., Zeches M., and Men-Oliver L.L. Phytochemistry 38 (1995) 767
75. Barboni L., Gariboldi P., Torregiani E., and Verotta L. Phytochemistry 35 (1994) 1579
76. Auvin C., Lezenven F., Blond A., Augeven-Bour I., Pousset J.-L., and Bodo B. J. Nat. Prod. 59 (1996) 676
77. Khokhar I., and Ahmad A. Sci. Int. (Lahore 5 (1993) 37
78. Chem. Abstr. 119 (1993) 245538
79. Jossang A., Zahir A., and Diakite D. Phytochemistry 42 (1996) 565
80. Khokhar I., and Ahmad A. Pak. J. Sci. 45 (1993) 54
81. Chem. Abstr. 122 (1995) 5434
82. Khokhar I., and Ahmad A. J. Nat. Sci. Math. 34 (1994) 171
83. Chem. Abstr. 123 (1995) 29541
84. Maurya S.K., Pandey D.P., Singh J.P., and Pandey V.B. Pharmazie 50 (1995) 372
85. Morel A., Herzog R., Biermann J., and Voelter W. Z. Naturforsch., Teil B 39 (1984) 1825
86. Herzog R., Morel A., Biermann J., and Voelter W. Hoppe-Seyler's Z. Physiol. Chem. 365 (1984) 1351
87. Herzog R., Morel A., Biermann J., and Voelter W. Chem. Ztg. 108 (1984) 406
88. Morel A., Herzog R., and Voelter W. Chimia 39 (1985) 98
89. Chem. Abstr. 103 (1985) 142245
90. Hennig P., Morel A., and Voelter W. Z. Naturforsch. Teil B 41 (1986) 1180
91. Voelter W., Morel A.F., Atta-ur-Rahman, and Qureshi M.M. Z. Naturforsch., Teil B 42 (1987) 467
92. Machado E.C., Zanatta N.M., and Morel A.F. Quim. Nov. 16 (1993) 397
93. Chem. Abstr. 121 (1994) 35954
94. Morel A.F., Machado E.C., and Wessjohann L.A. Phytochemistry 39 (1995) 431
95. Machado E.C., Filho A.A., Morel A.F., and Monache F.D. J. Nat. Prod. 58 (1995) 548
96. Dongo E., Ayafor J.F., Sondengam B.L., and Connolly J.D. J. Nat. Prod. 52 (1989) 840
97. Khokhar I., and Ahmad A. Sci. Int. (Lahore 4 (1992) 151
98. Chem. Abstr. 118 (1993) 230141
99. Gournelis D., Skaltsounis A.-K., Tellegwin F., and Koch M. J. Nat. Prod. 52 (1989) 306
100. Meurer B., Wray V., Wiermann R., and Strack D. Phytochemistry 27 (1988) 839
101. Martin-Tanguy J., Cabanne F., Perdrizet E., and Martin C. Phytochemistry 17 (1978) 1927
102. Smith T.A., Negrel J., and Bird C.R. Adv. Polyamine Res. 4 (1983) 347
103. Martin C., Kunesch G., Martin-Tanguy J., Negrel J., Paynot M., and Carre M. Plant Cell Rep. 4 (1985) 158
104. Cabanne F., Dalebroux M.A., Martin-Tanguy J., and Martin C. Physiol. Plantarum 53 (1981) 399
105. Martin-Tanguy J., Perdrizet E., Prevost J., and Martin C. Phytochemistry 21 (1982) 1939
106. Martin C., and Martin-Tanguy J. C. R. Acad. Sci. Paris Ser. III 293 (1981) 249
107. Pandey D.K., Tripathi R.N., Tripathi R.D., and Dixit S.N. Grana 22 (1983) 31
108. Smith T.A., and Best G.R. Phytochemistry 17 (1978) 1093
109. Alemayehu G., Abegaz B., Snatzke G., and Duddeck H. Phytochemistry 27 (1988) 3255
110. Strack D., Eilert U., Wray W., Wolff J., and Jaggy H. Phytochemistry 29 (1990) 2893
111. Sattar E.A., Glasl H., Nahrstedt A., Hilal S.H., Zaki A.Y., and El-Zalabani S.M.H. Phytochemistry 29 (1990) 3931
112. Pezzuto J.M., Che C.T., McPherson D.D., Zhu J.-P., Topcu G., Erdelmeier C.A.J., and Cordell G.A. J. Nat. Prod. 54 (1991) 1522
113. Mar W., Tan G.T., Cordell G.A., Pezzuto J.M., Jurcic K., Offermann F., Redl K., Steinke B., and Wagner H. J. Nat. Prod. 54 (1991) 1531
114. Pezzuto J.M., Mar W., Lin L.Z., Cordell G.A., Neszmelyi A., and Wagner H. Heterocycles 32 (1991) 1961
115. Pezzuto J.M., Mar W., Lin L.Z., Cordell G.A., Neszmelyi A., and Wagner H. Phytochemistry 31 (1992) 1795
116. Fiedler W., Lorenzi-Riatsch A., and Hesse M. Plant Med. 56 (1990) 493
117. Ahmad V.U., Arif S., Atta-ur-Rahman, Usmanghani K., and Miana G.A. Heterocycles 23 (1985) 3015
118. Ahmad V.U., Arif S., Atta-ur-Rahman, and Nasir M.A. Z. Forsch., Teil B 41 (1986) 1033
119. Ahmad V.U., Arif S., Atta-ur-Rahman, and Fizza K. Liebigs Ann. Chem. (1987) 161
120. Ahmad V.U., Ismail N., and Aziz ur Rahman A. Phytochemistry 28 (1989) 2493
121. Rashid S., Lodhi F., Ahmad M., and Usmanghani K. Pak. J. Pharmacol. 6 (1989) 61
122. Chem. Abstr. 114 (1991) 35631
123. Zhu J.P., Guggisberg A., and Hesse M. Helv. Chim. Acta 71 (1988) 218
124. Bernhard H.O., Kompis I., Johne S., Gröger D., Hesse M., and Schmid H. Helv. Chim. Acta 56 (1979) 1266
125. Bashwira S., and Hootele C. Tetrahedron 44 (1988) 4521
126. Diaz M., and Ripperger H. Phytochemistry 21 (1982) 255
127. Tawil B.F., Guggisberg A., and Hesse M. Tetrahedron 48 (1992) 3775
128. Ahmad V.U., and Sultana V. J. Nat. Prod. 53 (1990) 1162
129. Kuropka G., Koch M., and Glombitza K.W. Planta Med. (1986) 244
130. Bauer R., Remiger P., and Wagner H. Phytochemistry 27 (1988) 2339
131. Reisch J., Hussain R.A., Adesina S.K., and Szendrei K. J. Nat. Prod. 48 (1985) 862
132. Ahmed A., Aboul-Ela M.A., and El-Din A.A. Pharmazie 45 (1990) 941
133. Chem Abstr. 114 (1991) 203509
134. Xiao Y., Bi J., Liu X., and Tu Y. Zhiwu Xuebao 29 (1987) 532
135. Chem. Abstr. 108 (1988) 109524
136. Okwute S.K., Okogun J.I., and Okorie D.A. Tetrahedron 40 (1984) 2541
137. Shoji N., Umeyama A., Saito N., Takemoto T., Kayiwara A., and Ohizumi Y. J. Pharm. Sci. 75 (1986) 1188
138. Y. Ohizumi, A. Kajiwara, N. Shoji, and T. Takemoto, Jpn. Kokai Tokkyo koho, JP 62-178582
139. Chem. Abstr. 108 (1988) 11231
140. Maxwell A., and Rampersad D. J. Nat. Prod. 52 (1989) 411
141. Banerji A., and Das C. Phytochemistry 28 (1989) 3039
142. Adesina S.K. Planta Med. 55 (1989) 324
143. Adesina S.K., and Reisch J. Phytochemistr. 28 (1989) 839
144. Chen L.H., Xie L., and Xie J.X. Yaoxue Xuebao 25 (1990) 926
145. Chem. Abstr. 114 (1991) 142968
146. Bick I.R.C., Gunawardana Y.A.G.P., and Laraberton J.A. Tetrahedron 41 (1985) 5627
147. Mimaki Y., and Sashida Y. Chem. Pharm. Bull. 38 (1990) 541
148. Ahmad M.U., Islam M.R., Mirza A.H., Chowdhury B.H., and Nahar N. Ind. J. Chem. Soc., Sec. B 31 (1992) 67
149. Xu L., and Sun N. Yaoxue Xuebao 19 (1984) 48
150. Chem. Abstr. 101 (1984) 107360
151. Kubo I., Mtsumoto T., Klocke J.A., and Kamikawa T. Experientia 40 (1984) 340
152. Guha P.K., Poi R., and Bhattacharyya A. Phytochemistry 29 (1990) 2017
153. Sakakibara I., Katsuhara T., Ikeya Y., Hayashi K., and Mitsuhashi H. Phytochemistry 30 (1992) 3016
154. Sakakibara I., Ikeya Y., Hayashi K., and Mitsuhashi H. Phytochemistry 31 (1992) 3219
155. Yoshihara T., Yamaguchi K., Takamatsu S., and Sakamura S. Agric. Biol. Chem. 45 (1981) 2593
156. Kuo Y.H., and Jou M.H. Chem. Express 5 (1990) 909
157. Chem. Abstr. 114 (1991) 160675
158. Khokhar I., and Ahmad A. Sci. Int. (Lahore 4 (1992) 147
159. Chem. Abstr. 118 (1993) 230140
160. Colegate S.M., Dorling P.R., Huxtable C.R., Shaw T.J., Skelton B.W., Vogel P., and White A.H. Aust. J. Chem. 42 (1989) 1249
161. Byrne L.T., Guevara B.Q., Patalinghug W.C., Recio B.V., Ualat C.R., and White A.H. Aust. J. Chem. 45 (1992) 1903
162. Lin W., Xu R., and Zhong Q. Huaxue Xuebao 49 (1991) 927
163. Chem. Abstr. 116 (1992) 148198
164. Yue X., Shen Z., Lu L., Xu C., Li B., Wang C., and Xu X. Zhongguo Yiyae Gongye Zashi 22 (1991) 489
165. Chem. Abstr. 117 (1992) 123986
166. Shang L., Wen G., Zhou J., and Hao X. Yunnan Zhiwu Yanjiu 15 (1993) 299
167. Chem. Abstr. 120 (1994) 101930
168. Itokawa H., Takeya K., Mihashi S., Mori M., Hamanaka T., Sonobe T., and Iitaka Y. Chem. Pharm. Bull. 31 (1983) 1424
169. Itokawa H., Takeya K., Mori N., Hamanaka T., Sonobe T., and Mihara K. Chem. Pharm. Bull. 32 (1984) 284
170. Itokawa H., Takeya K., Moei M., Sonobe T., Serisawa N., Hamanaka T., and Mihashi S. Chem. Pharm. Bull. 32 (1984) 3216
171. Itokawa H., Takeya K., Mori N., Kidokoro S., and Hamanaka T. Planta Medica 51 (1984) 313
172. Itokawa H., Morita H., Takeya K., Tomioka N., Itai A., and Iitaka Y. Tetrahedron 47 (1991) 7007
173. Itokawa H., Takeya K., Mori N., Sonobe T., Mihashi S., and Hamanaka T. Chem. Pharm. Bull. 34 (1986) 3762
174. Itokawa H., Yamamiya T., Morita H., and Takeya K. J. Chem. Soc., Perkin Trans. 1 5 (1992)
175. Morita H., Yamamiya T., Takeya K., and Itokawa H. Chem. Pharm. Bull. 40 (1992) 1352
176. Takeya K., Yamamiya T., Morita H., and Itokawa H. Phytochemistry 33 (1993) 613
177. Itokawa H., Morita H., Takeya K., Tomioka N., and Itai A. Chem. Lett. (1991) 2217
178. Jolad S.D., Hoffman J.J., Torrance S.J., Wiedhoff R.M., Cole J.R., Arora S.K., Bates R.B., Gargiulo R.L., and Krik G.R. J. Am. Chem. Soc. 99 (1977) 8040
179. Bates R.B., Cole J., Hoffman J.J., Kriek G.R., Linz G.S., and Torrance S.J. J. Am. Chem. Soc. 105 (1983) 1343
180. Itokawa H., Takeya K., Mori N., Takanashi M., Yamamoto H., Sonobe T., and Kidokoro S. Gann 75 (1984) 929
181. Itokawa H., Takeya K., Mori N., Sonobe T., Hamanaka T., Mihashi S., Takanashi M., and Yamamoto H. J. Phamabio-Dun. 8 (1985) S63
182. Sirdeshpande B.V., and Toogood P.L. Bioorg. Chem. 23 (1995) 460
183. Inoue K., Mukaiyama T., Kobayashi T., and Ogawa M. Invest. New Drugs 4 (1986) 231
184. Itokawa H., Saitou K., Morita H., Takeya K., and Yamada K. Peptide Chem. (1991) 357
185. Itokawa H., Saitou K., Morita H., Takeya K., and Yamada K. Chem. Pharm. Bull. 40 (1992) 2984
186. Morita H., Yamamiya T., Takeya K., Itokawa H., Sakuma C., Yamada J., and Suga T. Chem. Pharm. Bull. 41 (1993) 781
187. Jolad S.D., Hoffmann J.J., Torrance S.J., Wiedhopf R.M., Cole J.R., Arora S.K., Bates R.B., Gargiulo R.L., and Kriek G.R. J. Am. Chem. Soc. 99 (1977) 8040
188. Morita H., Kondo K., Hitotsuyanagi Y., Takeya K., Itokawa H., Tomioka N., Itai A., and Iitaka Y. Tetrahedron 47 (1991) 2757
189. Itokawa H., Morita H., Takeya K., Tomioka N., Itai A., and Iitaka Y. Tetrahedron 47 (1991) 7007
190. Itokawa H., Morita H., Kondo K., Hitotsuyanagi Y., Takeya K., and Iitaka Y. J. Chem. Soc., Perkin Trans. 1 (1992) 1635
191. Hoffmann J.J., Torrance S.J., and Cole J.R. J. Chromatogr. Sci. 17 (1978) 287
192. Bates R.B., Cole J.R., Hoffmann J.J., Kriek G.R., Linz G.S., and Torrance S.J. J. Am. Chem. Soc. 105 (1983) 1343
193. Boger D.L., Patane M.A., and Zhou J. J. Am. Chem. Soc. 117 (1995) 7357
194. Itokawa H., Morita H., and Takeya K. Chem. Pharm. Bull. 40 (1992) 1050
195. Itokawa H., Saitou K., Morita H., and Takeya K. Chem. Pharm. Bull. 39 (1991) 2161
196. Boger D.L., and Zhou J. J. Am. Chem. Soc. 117 (1995) 7364
197. Itokawa H., Saitou K., Morita H., Takeya K., and Yamada K. Chem. Pharm. Bull. 40 (1992) 2984
198. Itokawa H., Morita H., Takeya K., Tomioka N., and Itai A. Chem Lett. (1991) 2217
199. Morita H., Yamamiyak T., Takeya K., Itokawa H., Sakuma C., Yamada J., and Suga T. Chem. Pharm. Bull. 41 (1993) 781
200. Senn H., Loosli H.R., Sanner M., and Braun W. Biopolymers 29 (1990) 1387
201. Bates R.B., Gin S.L., Hassen M.A., Hruby V.J., Janda K.D., Kriek G.R., Michaud J.-P., and Vine D.B. Heterocycles 22 (1984) 785
202. Boger D.L., and Yohannes D. J. Org. Chem. 53 (1988) 487
203. Boger D.L., and Yohannes D. SynLett. (1990) 33
204. Boger D.L., and Myers Jr. J.B. J. Org. Chem. 56 (1991) 5383
205. Boger D.L., Yohannes D., and Myers Jr. J.B. J. Org. Chem. 57 (1992) 1319
206. Boger D.L., Yohannes D., Zhou J., and Patane M.A. J. Am. Chem. Soc. 115 (1993) 3420
207. Boger D.L., Patane M.A., Jin Q., and Kitos P.A. Bioorg. Med. Chem. 2 (1994) 85
208. Itokawa H., Kondo K., Hitotsuyanagi Y., Nakamura A., Morita H., and Takeya K. Chem. Pharm. Bull. 41 (1993) 1266
209. Hitotsuyanagi Y., Lee S., Ito I., Kondo K., Takeya K., Yamagishi T., Nagate T., and Itokawa T. J. Chem. Soc., Perkin Trans. 1 (1996) 213
210. Itokawa H., Takeya K., Mori N., Sonobe T., Serizawa N., Hamanaka T., and Mihashi S. Chem. Pharm. Bull. 32 (1984) 3216
211. Itokawa H., Kondo K., Hitotsuyanagi Y., Isomura M., and Takeya K. Chem. Pharm. Bull. 41 (1993) 1402
212. Itokawa H., Kondo K., Hitotsuyanagi Y., and Takeya K. Heterocycles 36 (1993) 1837
213. Boger D.L., and Zhou J. J. Am. Chem. Soc. 117 (1995) 7364
214. Itokawa H., Suzuki J., Hitotsuyanagi Y., Kondo K., and Takeya K. Chem. Lett. (1993) 695
215. Hitotsuyanagi Y., Suzuki J., Takeya K., and Itokawa H. Bioorg. Med. Chem. Lett. 4 (1994) 1633
216. H. Itokawa and Y. Hitotsuyanagi, unpublished results.
217. Hitotsuyanagi Y., Suzuki J., Matsumoto Y., Takeya K., and Itokawa H. J. Chem. Soc., Perkin Trans. 1 (1994) 1887
218. Hitotsuyanagi Y., Matsumoto Y., Sasaki S., Suzuki J., Takeya K., Yamaguchi K., and Itokawa H. J. Chem. Soc., Perkin Trans. 1 (1996) 1749
219. Boger D.L., Zhou J., Winter B., and Kitos P.A. Bioorg. Med. Chem. 3 (1995) 1579
220. Hitotsuyanagi Y., Kondo K., Takeya K., and Itokawa H. Tetrahedron Lett. 35 (1994) 2191
221. Kosemura S., Ogawa T., and Totsuka K. Tetrahedron Lett. 34 (1993) 1291
222. Morita H., Nagashima S., Takeya K., and Itokawa H. Chem. Pharm. Bull. 41 (1993) 992
223. Nagao T., Okabe H., and Yamauchi T. Chem. Pharm. Bull. 36 (1988) 571
224. Marfey P. Carlsberg Res. Commun. 49 (1984) 591
225. Burke Jr. T.R., Knight M., Chandrasekhar B., and Ferretti J.A. Tetrahedron Lett. 30 (1989) 519
226. Flippin L.A., Jalali-Araghi K., and Brown P.A. J. Org. Chem. 54 (1989) 3006
227. Morita H., Nagashima S., Takeya K., Itokawa H., and Iitaka Y. Tetrahedron 51 (1995) 1121
228. Morita H., Nagashima S., Shirota O., Takeya K., and Itokawa H. Chem. Lett. (1993) 1877
229. Morita H., Nagashima S., Takeya K., and Itokawa H. Heterocycles 38 (1994) 2247
230. Morita H., Nagashima S., Takeya K., and Itokawa H. Chem. Lett. 11 (1994) 2009
231. Morita H., Nagashima S., Takeya K., and Itokawa H. Chem. Pharm. Bull. 43 (1995) 271
232. Cheng D., Shao Y., Hartman R., Roder E., and Zhao K. Phytochemistry 36 (1994) 945
233. Morita H., Nagashima S., Uchiumi Y., Kuroki O., Takeya K., and Itokawa H. Chem. Pharm. Bull. 44 (1996) 1026
234. Jiang J., Schumacher K.K., Joullie M.M., Davis F.A., and Reddy R.E. Tetrahedron Lett. 35 (1994) 2121
235. Williams L., Hauze D.B., and Joullie M.M. Heterocycl. Commun. 2 (1996) 55
236. Yoshioka H., Nakatsu K., Sato M., and Tatsuno T. Chem. Lett. (1973) 1319
237. Ciegler A., Kadis S., and Ajl S.J. "Microbial Toxins VI: Fungal Toxins," (1971), Academic Press, New York 345-352
238. Morita H., Nagashima S., Takeya K., and Itokawa H. Tetrahedron 50 (1994) 11613
239. Morita H., Nagashima S., Takeya K., and Itokawa H. Chem. Pharm. Bull. 43 (1995) 1395
240. Hoshi A., and Kuretani K. Farmacia 9 (1973) 464
241. Morita H., Nagashima S., Takeya K., and Itokawa H. BioMed. Chem. Lett. 5 (1995) 677
242. Morita H., Nagashima S., Takeya K., and Itokawa H. J. Chem. Soc., Perkin Trans. 1 (1995) 2327
243. Morita H., Kobata H., Takeya K., and Itokawa H. Tetrahedron Lett. 35 (1994) 3563
244. Morita H., Kayashita T., Kobata H., Gonda A., Takeya K., and Itokawa H. Tetrahedron 50 (1994) 6797
245. Morita H., Kayashita T., Kobata H., Gonda A., Takeya K., and Itokawa H. Tetrahedron 50 (1994) 9975
246. Morita H., Kayashita T., Takeya K., and Itokawa H. J. Nat. Prod. 58 (1995) 943
247. Chinese Academy of Medical Sciences. "Zhong Yao Zi," 2 (1985), The People's Health Publishing House, Beijing 266
248. Hearing V.J. Methods in Enzymology 142 (1987) 154
249. Ning-Hua T., Jun Z., Chang-Xiang C., and Shou-Xun Z. Phytochemistry 32 (1993) 1327
250. Morita H., Kayashita T., Takeya K., Itokawa H., and Shiro M. Tetrahedron 51 (1995) 12539
251. Morita H., Kayashita T., Takeya K., and Itokawa H. Chem. Pharm. Bull. 44 (1996) 2177
252. Morita H., Kayashita T., Takeya K., and Itokawa H. Tetrahedron 50 (1995) 12599
253. Morita H., Shishido A., Kayashita T., Shimomura M., Takeya K., and Itokawa H. Chem. Lett. (1994) 2415
254. Morita H., Kayashita T., Shimomura M., Takeya K., and Itokawa H. J. Nat. Prod. 59 (1996) 280
255. Morita H., Kayashita T., Shimomura M., Takeya K., and Itokawa H. Heterocycles 43 (1996) 1279
256. Wieland T., Hasan M., and Pfaender P.J. Liebigs Ann. Chem. 717 (1968) 205
257. Fowden L., Pratt H.M., and Smith A. Phytochemistry 12 (1973) 1707
258. Iitaka Y., Nakamura H., Takada K., and Takita T. Acta Crystallogr. B30 (1974) 2817
259. Stezowski J., Pohlman H.W., Haslinger E., Kalchhauser H., Schmidt U., and Pazolli B. Tetrahedron 43 (1987) 3923
260. Groth P. Acta Chem. Scand. A29 (1975) 38
261. Potgieter M., Steyn P.S., VanHeerden F.R., VanRooyen P.M., and Weswsels P.L. Tetrahedron 45 (1989) 2337
262. Eggleston D.S., Baures P.W., Peishoff C.E., and Kopple K.D. J. Am. Chem. Soc. 113 (1991) 4410
263. Kobayashi J., Tsuda M., Nakamura T., Mikami Y., and Shigemori H. Tetrahedron 49 (1993) 2391
264. Pettit G.R., Xu J., Cichacz Z.A., Williams M.D., Boyd M.R., and Cerny R.L. Biomed. Chem. Lett. 4 (1994) 2091
265. Zhao Y.-R., Zhuo J., Wang X.-K., Huang X.-L., and Wu H.-M. Acta Botanica Yunnanica 17 (1995) 345
266. Zhao Y.-R., Zhou J., Wang X.-K., Huang X.-L., Wu H.-M., and Zou C. Phytochemistry 40 (1995) 1453
267. Zhao Y.-R., Wang X.-K., Zhao T.-F., Zhou J., Huang X.-L., and Wu H.-M. Chin. J. Chem. 13 (1995) 267
268. Zhao Y.-R., Wang X.-K., Zhou J., Cheng C.-X., Huang X.-L., and Wu H.-M. Chin. J. Chem. 13 (1995) 552
269. In: Huang K.-C. (Ed). "The Pharmacology of Chinese Herbs" (1993), CRC Press, Boca Raton, FL 254-255
270. Morita H., Yun Y.S., Takeya K., and Itokawa H. Tetrahedron Lett. 35 (1994) 9593
271. Morita H., Yun Y.S., Takeya K., Itokawa H., and Yamada K. Tetrahedron 51 (1995) 6003
272. Morita H., Yun Y.S., Takeya K., Itokawa H., and Shirota O. Phytochemistry 42 (1996) 439
273. Yun Y.S., Morita H., Takeya K., and Itokawa H. J. Nat. Prod. 60 (1997) 216
274. Bruins A.P., Corey T.R., and Henion J.D. Anal. Chem. 59 (1987) 2642
275. In: McLafferty F.W. (Ed). "Tandem Mass Spectrometry" (1983), Wiley, New York
276. Itokawa H., Yun Y.S., Morita H., Takeya K., and Yamada K. Planta Med. 61 (1995) 561
277. Amico J.A., Seif S.M., and Robinson A.G. J. Clin. Endocrinol. Metab. 52 (1981) 988
278. Axelson M., Sjovall J., Gustafsson B.E., and Setchell K.D.R. J. Endocrinol. 102 (1984) 49
279. Morita H., Yun Y.S., Takeya K., Itokawa H., and Shiro M. Tetrahedron 51 (1995) 5987
280. "38th Symposium on the Chemistry of Natural Products, Sendai, Symposium Papers Ph.D. Thesis 1996 289-294
281. Morita H., Kayashita T., Shishido A., Takeya K., Itokawa H., and Shiro M. Biomed. Chem. Lett. 5 (1995) 2353
282. Morita H., Kayashita T., Shishido A., Takeya K., Itokawa H., and Shiro M. Tetrahedron 52 (1996) 1165
283. Liu M.S., Chen Y.J., Wang Y.H., Xing S.R., Takido M., and Yasukawa K. Acta Pharm. Sinica 27 (1992) 667
284. H. Morita, A. Shishido, T. Kayashita, K. Takeya, and H. Itokawa, J. Nat. Prod., in press.
285. H. Morita, K. Takeya, and H. Itokawa, Phytochemistry, in press.
286. Morita H., Kayashita T., Uchida A., Takeya K., and Itokawa H. J. Nat. Prod. 60 (1997) 212
287. Zhao Y.R., Zhou J., Wang X.K., Wu H.M., and Huang X.L. Chin. Chem. Lett. 6 (1995) 1041
288. Zhao Y.R., Zhou J., Wang X.K., Wu H.M., and Huang X.L. Chin. Chem. Lett. 7 (1996) 149
289. Jiang Su New Medical College. "Zhong Yao Da Ci Dian," 2 (1977), Shanghai Science and Technology Press, Shanghai 1609-1610
290. Chinese Academy of Medical Science and others. "Zhong Yao Zhi," 3 (1984), People's Health Publisher, Beijing 513-516
291. Wang C.-E., Yano S., Watanabe K., Natori S., Yamada K., and Fujimoto Y. J. Med. Pharm. Soc. Wakan-Yaku 3 (1986) 446
292. Kinoshita K., Tanaka J., Kuroda K., Koyama K., Natori S., and Kinoshita T. Chem. Pharm. Bull. 39 (1991) 712
293. Morita H., Gonda A., Takeya K., and Itokawa H. Biomed. Chem. Lett. 6 (1996) 767
294. Morita H., Gonda A., Takeya K., Itokawa H., and Iitaka Y. Tetrahedron 53 (1997) 1617
295. Morita H., Gonda A., Takeya K., and Itokawa H. Chem. Pharm. Bull. 45 (1997) 161
296. Li C.-M., Tan N.-H., Lu Y.-P., Liang H.-L., Mu Q., Zheng H.-L., Hao X.-J., and Zhou J. Yunnan Zhiwu Yanjiu 17 (1995) 459
297. Chem. Abstr. 124 (1996) 170600s
298. Zhao Y.R., Zhou J., Wang X.K., Huang X.L., Wu H.M., and Zhao T.F. Chin. Chem. Lett. 5 (1994) 751
299. Chem. Abstr. 122 (1995) 101559
300. Matsubara Y., Yusa T., Sawabe A., Iizuka Y., Takekuma S.-I., and Yoshida Y. Agric. Biol. Chem. 55 (1991) 2923
301. Bashwira S., Hootelé C., Tourwé D., Pepermans H., Laus G., and van Binst G. Tetrahedron 45 (1989) 5845
302. Declercq J.P., Tinant B., Bashwira S., and Hootelé C. Acta Crystallogr., Sect. C: Cryst. Struct. C46 (1990) 1259
303. van den Berg A.J.J., Horsten S.F.A.J., Kettenes-van den Bosch J.J., Kroes B.H., Beukelman C.J., Leeflang B.R., and Labadie R.P. FEBS Lett. 358 (1995) 215
304. Kinoshita K., Tanaka J., Kuroda K., Koyama K., Natori S., and Kinoshita T. Chem. Pharm. Bull. 39 (1991) 712
305. Witherup K.M., Bogusky M.J., Anderson P.S., Ramjit H., Ransom R.W., Wood T., and Sardana M. J. Nat. Prod. 57 (1994) 1619
306. Horsten S.F.A.J., van den Berg A.J.J., Kettenes-van den Bosch J.J., Leeflang B.R., and Labadie R.P. Planta Med. 62 (1996) 46
307. Li C.M., Tan N.H., Zheng H.L., Hao X.J., and Zhou J. Chin. Chem. Lett. 6 (1995) 39
308. Chem. Abstr. 122 (1995) 235259
309. Tan N., Zhou J., Zhao S., Zhang H., Wang D., Chen C., and Liu X. Chin. Chem. Lett. 3 (1992) 629
310. Chem. Abstr. 118 (1993) 56137
311. Tan N.-H., Zhou J., Chen C.-X., and Zhao S.-X. Phytochemistry 32 (1993) 1327
312. Tan N., and Zhou J. Yunnan Zhiwu Yanjiu 17 (1995) 60
313. Chem. Abstr. 123 (1995) 107750
314. Kosasi S., van der Sluis W.G., Boelens R., 't Hart L.A., and Labadie R.P. FEBS Lett. 256 (1989) 91
315. Yahara S., Shigeyama C., Nohara T., Okuda H., Wakamatsu K., and Yasuhara T. Tetrahedron Lett. 30 (1989) 6041
316. Schmidt U., and Stabler F. J. Chem. Soc., Chem. Commun. (1992) 1353
317. Yahara S., Shigeyama C., Ura T., Wakamatsu K., Yasuhara T., and Nohara T. Chem. Pharm. Bull. 41 (1993) 703
318. Morita H., Yoshida N., Takeya K., Itokawa H., and Shirota O. Tetrahedron 52 (1996) 2795
319. Leung T.-W.C., Williams D.H., Barna J.C.J., Foti S., and Oelrichs P.B. Tetrahedron 42 (1986) 3333
320. Kahn S.D., Booth P.M., Waltho J.P., and Williams D.H. J. Org. Chem. 54 (1989) 1901
321. van den Berg A.J.J., Horsten S.F.A.J., Kettenes-van den Bosch J.J., Beukelman C.J., Kroes B.H., Leefiang B.R., and Labadie R.P. Phytochemistry 42 (1996) 129
322. He M., Zou C., Hao X.J., and Zhou J. Chin. Chem. Lett. 4 (1993) 1065
323. Chem. Abstr. 121 (1994) 31180e
324. Chen Y., Liu M., Wang Y., Xing S., Yasukawa K., and Takido M. Zhongguo Yaowu Huaxue Zazhi 1 (1990) 73
325. Chem. Abstr. 115 (1991) 275712
326. Wang Y., Xing S., Liu M., Chen Y., Yasukawa K., and Takido M. Shenyang Yaoxueyuan Xuebao 8 (1991) 269
327. Chem. Abstr. 116 (1992) 231870
328. Liu M., Chen Y., Wang Y., Xing S., Takido M., and Yasukawa K. Acta Pharm. Sinica 27 (1992) 667
329. Zhao Y.R., Zhou J., Wang X.K., Wu H.M., and Huang X.L. Chin. Chem. Lett. 6 (1995) 1041
330. Chem. Abstr. 124 (1996) 82173
331. Zhao Y.R., Zhou J., Wang X.K., Wu H.M., and Huang X.L. Chin. Chem. Lett. 7 (1996) 149
332. Chem. Abstr. 124 (1996) 255763
333. Zhao Y.R., Zhou J., Wang K., Huang X.L., Wu H.M., and Cheng C.X. Chin. Chem. Lett. 7 (1996) 237
334. Chem. Abstr. 124 (1996) 255761
335. Zhao Y., Zhou J., and Wang X. Yunnan Zhiwu Yanjiu 15 (1993) 207
336. Chem. Abstr. 120 (1994) 71795
337. Zhao Y., Zhou J., Wang X., Huang X., and Wu H. Yunnan Zhiwu Yanjiu 17 (1995) 345
338. Chem. Abstr. 124 (1996) 4973
339. Zhao Y., Zhou J., Wang X., Wu H., Huang X., and Zhou C. Chin. Chem. Lett. 5 (1994) 127
340. Chem. Abstr. 121 (1994) 129891
341. Zhao Y.-R., Zhou J., Wang X.-K., Huang X.-L., Wu H.-M., and Zou C. Phytochemistry 40 (1995) 1453
342. Zhao Y.-R., Wang X.-K., Zhao T.-F., Zhou J., Huang X.-L., and Wu H.-M. Chin. J. Chem. 13 (1995) 267
343. Chem. Abstr. 123 (1995) 107825
344. Zhao Y.-R., Wang X.-K., Zhou J., Cheng C.-X., Huang X.-L., and Wu H.-M. Chin. J. Chem. 13 (1995) 552
345. Chem. Abstr. 124 (1996) 141005
346. Zhao Y.-R., Zhou J., Wang X.-K., Huang X.-L., Wu H.-M., Tan N.-H., and Cheng C.-X. Yunnan Zhiwu Yanjiu 17 (1995) 463
347. Chem. Abstr. 124 (1996) 255732
348. H. Morita, A. Gonda, K. Takeya, H. Itokawa, T. Hirano, K. Oka, and O. Shirota, Tetrahedron, in press.