A specific interaction of small molecule entry inhibitors with the envelope glycoprotein complex of the Junín hemorrhagic fever arenavirus

Journal of Biological Chemistry

Volumn 286, Issue 8, 2011, Pages 6192-6200

  Thomas, Celestine J ^a   Casquilho Gray, Hedi E ^a   York, Joanne ^a   DeCamp, Dianne L ^a   Dai, Dongcheng ^b   Petrilli, Erin B ^c   Boger, Dale L ^d   Slayden, Richard A ^c   Amberg, Sean M ^b   Sprang, Stephen R ^a   Nunberg, Jack H ^a  

^a UNIVERSITY OF MONTANA   (United States)

^b SIGA Technologies Incorporated   (United States)

^c Department of Ecosystem Science and Sustainability   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; BINDING POCKETS; BIODEFENSE; CELL SURFACE RECEPTORS; COMPETITIVE BINDING; DISSOCIATION CONSTANT; ENDOSOMES; ENVELOPE GLYCOPROTEINS; GENETIC STUDIES; MEMBRANE FUSION; NATIVE PROTEINS; OLD WORLDS; PUBLIC HEALTH; SIGNAL PEPTIDE; SMALL MOLECULES; SPECIFIC INTERACTION; TRANSFERRIN RECEPTORS; TRANSMEMBRANES;

CELL MEMBRANES; DISSOCIATION; GLYCOPROTEINS; HEALTH RISKS; LIPID BILAYERS; OLIGOMERS;

MOLECULES;

ANTIVIRUS AGENT; CD71 ANTIGEN; PIBENZIMOL; PROTEIN GPC; ST 161; ST 193; ST 294; ST 545; ST 761; TOLONIDINE; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG PROTEIN BINDING; JUNIN VIRUS; LIPID BILAYER; MEMBRANE FUSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; SPECIES DIFFERENCE;

ANIMALS; ANTIGENS, CD; ANTIVIRAL AGENTS; ARENAVIRIDAE INFECTIONS; CERCOPITHECUS AETHIOPS; HUMANS; JUNIN VIRUS; RECEPTORS, TRANSFERRIN; VERO CELLS; VIRAL ENVELOPE PROTEINS; VIRUS INTERNALIZATION;

ANIMALIA; ARENAVIRUS; JUNIN VIRUS; OLD WORLD ARENAVIRUSES;

EID: 79953212241     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.196428     Document Type: Article

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