Yeast cells lacking all known ceramide synthases continue to make complex sphingolipids and to incorporate ceramides into glycosylphosphatidylinositol (GPI) anchors

Journal of Biological Chemistry

Volumn 286, Issue 8, 2011, Pages 6769-6779

  Vionnet, Christine ^a   Roubaty, Carole ^a   Ejsing, Christer S ^b   Knudsen, Jens ^b   Conzelmann, Andreas ^a  

^a UNIVERSITY OF FRIBOURG   (Switzerland)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDES; GAIN-OF FUNCTION; GENETIC BACKGROUNDS; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORS; OVER-EXPRESSION; PHOSPHATIDYLINOSITOL; SPHINGOID BASIS; SPHINGOLIPIDS; SYNTHASES; THERMO SENSITIVE; YEAST CELL;

ANCHORS; FATTY ACIDS; GLYCEROL; LIPIDS; PLANTS (BOTANY); SUGARS; YEAST;

AMIDES;

CERAMIDE; GLYCOSYLPHOSPHATIDYLINOSITOL; SPHINGOLIPID; SPHINGOSINE ACYLTRANSFERASE;

ARTICLE; AUR1 GENE; CONTROLLED STUDY; FUNGAL STRAIN; FUNGAL VIABILITY; FUNGUS GROWTH; FUNGUS MUTANT; GENE; GENE DELETION; GENE EXPRESSION; GENE OVEREXPRESSION; LAG1 GENE; LIPOGENESIS; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SLC1 1 GENE; YEAST CELL; YPC1 GENE;

CERAMIDES; GENE DELETION; GLYCOSYLPHOSPHATIDYLINOSITOLS; OXIDOREDUCTASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPHINGOLIPIDS;

SPHINGOIDEA;

EID: 79953211538     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.176875     Document Type: Article

References (59)

1. Dickson, R. C., and Lester, R. L. (1999) Biochim. Biophys. Acta 1438, 305-321
2. Dickson, R. C., and Lester, R. L. (2002) Biochim. Biophys. Acta 1583, 13-25
3. Sims, K. J., Spassieva, S. D., Voit, E. O., and Obeid, L. M. (2004) Biochem. Cell Biol. 82, 45-61
4. Dickson, R. C., Sumanasekera, C., and Lester, R. L. (2006) Prog. Lipid Res. 45, 447-465
5. Dickson, R. C. (2008) J. Lipid Res. 49, 909-921
6. Matmati, N., Kitagaki, H., Montefusco, D., Mohanty, B. K., and Hannun, Y. A. (2009) J. Biol. Chem. 284, 8241-8246
7. D'mello, N. P., Childress, A. M., Franklin, D. S., Kale, S. P., Pinswasdi, C., and Jazwinski, S. M. (1994) J. Biol. Chem. 269, 15451-15459
8. Winter, E., and Ponting, C. P. (2002) Trends Biochem. Sci 27, 381-383
9. Vallée, B., and Riezman, H. (2005) EMBO J. 24, 730-741
10. Jiang, J. C., Kirchman, P. A., Zagulski, M., Hunt, J., and Jazwinski, S. M. (1998) Genome Res. 8, 1259-1272
11. Barz, W. P., and Walter, P. (1999) Mol. Biol. Cell 10, 1043-1059
12. Mao, C., Xu, R., Bielawska, A., and Obeid, L. M. (2000) J. Biol. Chem. 275, 6876-6884
13. Cerantola, V., Guillas, I., Roubaty, C., Vionnet, C., Uldry, D., Knudsen, J., and Conzelmann, A. (2009) Mol. Microbiol. 71, 1523-1537
14. Nagiec, M. M., Wells, G. B., Lester, R. L., and Dickson, R. C. (1993) J. Biol. Chem. 268, 22156-22163
15. Lester, R. L., Wells, G. B., Oxford, G., and Dickson, R. C. (1993) J. Biol. Chem. 268, 845-856
16. Gaigg, B., Timischl, B., Corbino, L., and Schneiter, R. (2005) J. Biol. Chem. 280, 22515-22522
17. Gaigg, B., Toulmay, A., and Schneiter, R. (2006) J. Biol. Chem. 281, 34135-34145
18. Dickson, R. C., Nagiec, E. E., Skrzypek, M., Tillman, P., Wells, G. B., and Lester, R. L. (1997) J. Biol. Chem. 272, 30196-30200
19. Nagiec, M. M., Skrzypek, M., Nagiec, E. E., Lester, R. L., and Dickson, R. C. (1998) J. Biol. Chem. 273, 19437-19442
20. Uemura, S., Kihara, A., Inokuchi, J., and Igarashi, Y. (2003) J. Biol. Chem. 278, 45049-45055
21. Lisman, Q., Pomorski, T., Vogelzangs, C., Urli-Stam, D., de Cocq van Delwijnen, W., and Holthuis, J. C. (2004) J. Biol. Chem. 279, 1020-1029
22. Thevissen, K., Idkowiak-Baldys, J., Im, Y. J., Takemoto, J., François, I. E., Ferket, K. K., Aerts, A. M., Meert, E. M., Winderickx, J., Roosen, J., and Cammue, B. P. (2005) FEBS Lett. 579, 1973-1977
23. Endo, M., Takesako, K., Kato, I., and Yamaguchi, H. (1997) Antimicrob. Agents Chemother. 41, 672-676
24. Nagiec, M. M., Nagiec, E. E., Baltisberger, J. A., Wells, G. B., Lester, R. L., and Dickson, R. C. (1997) J. Biol. Chem. 272, 9809-9817
25. Schorling, S., Vallée, B., Barz, W. P., Riezman, H., and Oesterhelt, D. (2001) Mol. Biol. Cell 12, 3417-3427
26. Guillas, I., Kirchman, P. A., Chuard, R., Pfefferli, M., Jiang, J. C., Jazwinski, S. M., and Conzelmann, A. (2001) EMBO J. 20, 2655-2665
27. Sherman, F. (2002) Methods Enzymol. 350, 3-41
28. Mumberg, D., Müller, R., and Funk, M. (1994) Nucleic Acids Res. 22, 5767-5768
29. Cerantola, V., Vionnet, C., Aebischer, O. F., Jenny, T., Knudsen, J., and Conzelmann, A. (2007) Biochem. J. 401, 205-216
30. Hansen, J., Felding, T., Johannesen, P. F., Piskur, J., Christensen, C. L., and Olesen, K. (2003) FEMS Yeast Res. 4, 323-327
31. Voth, W. P., Jiang, Y. W., and Stillman, D. J. (2003) Yeast 20, 985-993
32. Fujita, M., and Jigami, Y. (2008) Biochim. Biophys. Acta 1780, 410-420
33. Ghugtyal, V., Vionnet, C., Roubaty, C., and Conzelmann, A. (2007) Mol. Microbiol. 65, 1493-1502
34. Umemura, M., Fujita, M., Yoko-O, T., Fukamizu, A., and Jigami, Y. (2007) Mol. Biol. Cell 18, 4304-4316
35. Zhu, Y., Vionnet, C., and Conzelmann, A. (2006) J. Biol. Chem. 281, 19830-19839
36. Reggiori, F., and Conzelmann, A. (1998) J. Biol. Chem. 273, 30550-30559
37. Guillas, I., Pfefferli, M., and Conzelmann, A. (2000) Methods Enzymol. 312, 506-515
38. Reggiori, F., Canivenc-Gansel, E., and Conzelmann, A. (1997) EMBO J. 16, 3506-3518
39. Ejsing, C. S., Sampaio, J. L., Surendranath, V., Duchoslav, E., Ekroos, K., Klemm, R. W., Simons, K., and Shevchenko, A. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 2136-2141
40. Oh, C. S., Toke, D. A., Mandala, S., and Martin, C. E. (1997) J. Biol. Chem. 272, 17376-17384
41. Hanson, B. A., and Lester, R. L. (1980) J. Lipid Res. 21, 309-315
42. Pinto, W. J., Srinivasan, B., Shepherd, S., Schmidt, A., Dickson, R. C., and Lester, R. L. (1992) J. Bacteriol. 174, 2565-2574
43. Sato, K., Noda, Y., and Yoda, K. (2009) Mol. Biol. Cell 20, 4444-4457
44. Heidler, S. A., and Radding, J. A. (1995) Antimicrob. Agents Chemother. 39, 2765-2769
45. Hashida-Okado, T., Ogawa, A., Endo, M., Yasumoto, R., Takesako, K., and Kato, I. (1996) Mol. Gen. Genet 251, 236-244
46. Schneiter, R., Brügger, B., Amann, C. M., Prestwich, G. D., Epand, R. F., Zellnig, G., Wieland, F. T., and Epand, R. M. (2004) Biochem. J. 381, 941-949
47. Benghezal, M., Roubaty, C., Veepuri, V., Knudsen, J., and Conzelmann, A. (2007) J. Biol. Chem. 282, 30845-30855
48. Jenkins, G. M., Richards, A., Wahl, T., Mao, C., Obeid, L., and Hannun, Y. (1997) J. Biol. Chem. 272, 32566-32572
49. Wells, G. B., Dickson, R. C., and Lester, R. L. (1998) J. Biol. Chem. 273, 7235-7243
50. Patton, J. L., Srinivasan, B., Dickson, R. C., and Lester, R. L. (1992) J. Bacteriol. 174, 7180-7184
51. Munn, A. L., and Riezman, H. (1994) J. Cell Biol. 127, 373-386
52. Chung, N., Mao, C., Heitman, J., Hannun, Y. A., and Obeid, L. M. (2001) J. Biol. Chem. 276, 35614-35621
53. Friant, S., Meier, K. D., and Riezman, H. (2003) EMBO J. 22, 3783-3791
54. Meier, K. D., Deloche, O., Kajiwara, K., Funato, K., and Riezman, H. (2006) Mol. Biol. Cell 17, 1164-1175
55. Mir, S. S., Fiedler, D., and Cashikar, A. G. (2009) Mol. Cell Biol. 29, 187-200
56. Pittet, M., Uldry, D., Aebi, M., and Conzelmann, A. (2006) Glycobiology 16, 155-164
57. Fankhauser, C., Homans, S. W., Thomas-Oates, J. E., McConville, M. J., Desponds, C., Conzelmann, A., and Ferguson, M. A. (1993) J. Biol. Chem. 268, 26365-26374
58. Zanolari, B., Friant, S., Funato, K., Sütterlin, C., Stevenson, B. J., and Riezman, H. (2000) EMBO J. 19, 2824-2833
59. Hearn, J. D., Lester, R. L., and Dickson, R. C. (2003) J. Biol. Chem. 278, 3679-3686