Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry

Protein and Cell

Volumn 1, Issue 7, 2010, Pages 664-674

  Brown, Kristelle S ^a   Keogh, Michael J ^a   Owsianka, Ania M ^b   Adair, Richard ^b   Patel, Arvind H ^b,d   Arnold, James N ^c   Ball, Jonathan K ^a   Sim, Robert B ^c   Tarr, Alexander W ^a   Hickling, Timothy P ^a,e  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b MRC UNIVERSITY OF GLASGOW CENTRE FOR VIRUS RESEARCH   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d Vitrology Biotech   (United Kingdom)

^e PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

chronic viral infection; hepatitis C virus; mannose binding lectin; neutralization

Indexed keywords

COMPLEMENT COMPONENT C4B; GLYCOPROTEIN E1; GLYCOPROTEIN E2; HETERODIMER; MANNAN BINDING LECTIN; MANNAN BINDING LECTIN ASSOCIATED SERINE PROTEINASE; MANNAN BINDING LECTIN ASSOCIATED SERINE PROTEINASE 2; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; COMPLEMENT ACTIVATION; COMPLEMENT DEPOSITION; COMPLEMENT FIXATION; CONTROLLED STUDY; DIMERIZATION; GENOTYPE; HEPATITIS C VIRUS; HEPATOMA CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; VIRUS ENTRY; VIRUS NEUTRALIZATION; VIRUS STRAIN;

HEPATITIS C VIRUS;

EID: 79953210378     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-010-0088-9     Document Type: Article

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