메뉴 건너뛰기




Volumn 64, Issue 3, 2011, Pages 277-280

N,N′-diphenethylurea isolated from Okinawan ascidian Didemnum molle enhances adipocyte differentiation in 3T3-L1 cells

Author keywords

adipocyte differentiation; insulin signal; N,N diphenethylurea; PPAR

Indexed keywords

1,3 DI(2 PHENYLETHYL)UREA; ANTIDIABETIC AGENT; INSULIN; ROSIGLITAZONE; UNCLASSIFIED DRUG; 1,3-DIPHENETHYLUREA; DRUG DERIVATIVE; UREA;

EID: 79953203210     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2010.168     Document Type: Article
Times cited : (10)

References (14)
  • 2
    • 0031821520 scopus 로고    scopus 로고
    • Understanding adipocyte differentiation
    • Gregoire, F. M., Smas, C. M. & Sul, H. S. Understanding adipocyte differentiation. Physiol Rev 78, 783-809 (1998).
    • (1998) Physiol Rev , vol.78 , pp. 783-809
    • Gregoire, F.M.1    Smas, C.M.2    Sul, H.S.3
  • 3
    • 0031898610 scopus 로고    scopus 로고
    • PPAR-gamma: Adipogenic regulator and thiazolidinedione receptor
    • Spiegelman, B. M. PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. Diabetes 47, 507-514 (1998).
    • (1998) Diabetes , vol.47 , pp. 507-514
    • Spiegelman, B.M.1
  • 4
    • 23644456172 scopus 로고    scopus 로고
    • Therapeutic roles of peroxisome proliferator-activated receptor agonist
    • Staels, B. & Fruchart, J. C. Therapeutic roles of peroxisome proliferator-activated receptor agonist. Diabetes 54, 2460-2470 (2005).
    • (2005) Diabetes , vol.54 , pp. 2460-2470
    • Staels, B.1    Fruchart, J.C.2
  • 5
    • 0029080520 scopus 로고
    • Wortmannin, a specific phophatidylinositol 3-kinase inhibitor, inhibits adipocytic differentiation of 3T3-L1 cells
    • Tomiyama, K. et al. Wortmannin, a specific phophatidylinositol 3-kinase inhibitor, inhibits adipocytic differentiation of 3T3-L1 cells. Biochem. Biophy. Res. Commun. 212, 263-269 (1995).
    • (1995) Biochem. Biophy. Res. Commun. , vol.212 , pp. 263-269
    • Tomiyama, K.1
  • 6
    • 0001632060 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation
    • Font de Mora, J., Porras, A., Ahn, N. & Santos, E. Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation. Mol. Cell. Biol. 17, 6068-6075 (1997).
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6068-6075
    • Font De Mora, J.1    Porras, A.2    Ahn, N.3    Santos, E.4
  • 7
    • 0037195843 scopus 로고    scopus 로고
    • Activation of MEK/ERK signaling promotes adipogenesis by enhancing peroxisome proliferator-activated receptor γ (PPAR γ) and C/EBPα gene expression during the differentiation of 3T3-L1 preadipocytes
    • Prusty, D., Park, B. H., Davis, K. E. & Garmer, S. R. Activation of MEK/ERK signaling promotes adipogenesis by enhancing peroxisome proliferator-activated receptor γ (PPAR γ) and C/EBPα gene expression during the differentiation of 3T3-L1 preadipocytes. J. Biol. Chem. 277, 46226-46232 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 46226-46232
    • Prusty, D.1    Park, B.H.2    Davis, K.E.3    Garmer, S.R.4
  • 8
    • 4143153021 scopus 로고    scopus 로고
    • Protein kinase B/AKT 1 plays a pivotal role in insulin-like growth factor-1 receptor signaling induced 3T3-L1 adipocyte differentiation
    • Xu, J. & Liao, K. Protein kinase B/AKT 1 plays a pivotal role in insulin-like growth factor-1 receptor signaling induced 3T3-L1 adipocyte differentiation. J. Biol. Chem. 279, 35914-35922 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 35914-35922
    • Xu, J.1    Liao, K.2
  • 9
    • 0029775642 scopus 로고    scopus 로고
    • Insulin-and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferator-activated receptor γ
    • Zhang, B. et al. Insulin-and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferator-activated receptor γ. J. Biol. Chem. 271, 31771-31774 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 31771-31774
    • Zhang, B.1
  • 10
    • 0034637103 scopus 로고    scopus 로고
    • Inhibition of adipogenesis by Wnt signaling
    • Ross, S. E. et al. Inhibition of adipogenesis by Wnt signaling. Science 289, 950-953 (2000).
    • (2000) Science , vol.289 , pp. 950-953
    • Ross, S.E.1
  • 11
    • 0028171870 scopus 로고
    • Possible involvement of phosphatidylinositol-sepecific phospholipase C related to pertussis toxin sensitive GTP-binding proteins during adipocyte differentiation of 3T3-L1 fibroblast: Negative regulation of protein kinase C
    • Uehara, T., Hoshino, S., Ui, M., Tokumitsu, Y. & Nomura, Y. Possible involvement of phosphatidylinositol-sepecific phospholipase C related to pertussis toxin sensitive GTP-binding proteins during adipocyte differentiation of 3T3-L1 fibroblast: negative regulation of protein kinase C. Biochimica. et Biophysica. Acta. 1224, 302-310 (1994).
    • (1994) Biochimica. et Biophysica. Acta , vol.1224 , pp. 302-310
    • Uehara, T.1    Hoshino, S.2    Ui, M.3    Tokumitsu, Y.4    Nomura, Y.5
  • 12
    • 0032520921 scopus 로고    scopus 로고
    • Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats
    • Okuno, A . et al. Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J. Clin. Invest. 101, 1354-1361 (1998).
    • (1998) J. Clin. Invest. , vol.101 , pp. 1354-1361
    • Okuno, A.1
  • 13
    • 0029806069 scopus 로고    scopus 로고
    • Troglitazone enhance differentiation, basal glucose uptake, and Glut1 protein levels in 3T3-L1 adipocytes
    • Tafuri, S. R. Troglitazone enhance differentiation, basal glucose uptake, and Glut1 protein levels in 3T3-L1 adipocytes. Endocrinology 137, 4706-4712 (1996).
    • (1996) Endocrinology , vol.137 , pp. 4706-4712
    • Tafuri, S.R.1
  • 14
    • 1442352339 scopus 로고    scopus 로고
    • Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: Peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach
    • Bays, H., Mandarino, L. & DeFronzo, R. A. Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach. J. Clin. Endocrinol. Metab. 89, 463-478 (2004).
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 463-478
    • Bays, H.1    Mandarino, L.2    DeFronzo, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.