Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 A ° resolution

Protein Science

Volumn 20, Issue 4, 2011, Pages 670-683

  Schalk Hihi, Céline ^a   Schubert, Carsten ^a   Alexander, Richard ^a   Bayoumy, Shariff ^a   Clemente, Jose C ^a   Deckman, Ingrid ^a   DesJarlais, Renee L ^a   Dzordzorme, Keli C ^a   Flores, Christopher M ^a   Grasberger, Bruce ^a   Kranz, James K ^a   Lewandowski, Frank ^a   Liu, Li ^a   Ma, Hongchang ^a   Maguire, Diane ^a   Macielag, Mark J ^a   McDonnell, Mark E ^a   Haarlander, Tara Mezzasalma ^a   Miller, Robyn ^a   Milligan, Cindy ^a   Reynolds, Charles ^a   Kuo, Lawrence C ^a   more..

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Cannabinoid receptor; Lid domain; Monoglyceride lipase; Protein inhibitor complex

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ACYLGLYCEROL LIPASE; MEMBRANE PROTEIN;

ARTICLE; CATALYSIS; CONFORMATION; CRYSTAL STRUCTURE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PURIFICATION; PROTEIN STRUCTURE; STATIC ELECTRICITY;

ARACHIDONIC ACIDS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENDOCANNABINOIDS; GLYCERIDES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MONOACYLGLYCEROL LIPASES; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STATIC ELECTRICITY;

EID: 79953202170     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.596     Document Type: Article

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