Effects of diabetes and obesity on vascular reactivity, inflammatory cytokines, and growth factors

Obesity

Volumn 19, Issue 4, 2011, Pages 729-735

  Doupis, John ^a   Rahangdale, Shilpa ^b   Gnardellis, Charalambos ^c   Pena, Salvador E ^a   Malhotra, Atul ^b   Veves, Aristidis ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c TECHNOLOGICAL EDUCATIONAL INSTITUTE OF PATRAS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CYTOKINE; GLYCERYL TRINITRATE; GROWTH FACTOR; INTERCELLULAR ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ADULT; AGED; ARTICLE; BLOOD VESSEL REACTIVITY; BRACHIAL ARTERY; CONTROLLED STUDY; DIABETES MELLITUS; ENDOTHELIUM; FEMALE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; OBESITY; SKIN BLOOD FLOW; VASODILATATION;

ADULT; AGED; AGED, 80 AND OVER; BODY COMPOSITION; BODY MASS INDEX; BRACHIAL ARTERY; C-REACTIVE PROTEIN; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS; FEMALE; FOREARM; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OBESITY; REGRESSION ANALYSIS; SKIN; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTORS; VASODILATION; YOUNG ADULT;

EID: 79953195109     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2010.193     Document Type: Article

References (29)

1. Pischon T, Boeing H, Hoffmann K et al. General and abdominal adiposity and risk of death in Europe. N Engl J Med 2008;359:2105-2120.
2. Steinberg HO, Chaker H, Leaming R et al. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 1996;97:2601-2610.
3. Libby P. Inflammation in atherosclerosis. Nature 2002;420:868-874 (Pubitemid 36019640)
4. Esposito K, Nappo F, Marfella R et al. Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress. Circulation 2002;106:2067-2072. (Pubitemid 35192812)
5. Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000;342:836-843 (Pubitemid 30165206)
6. Diagnosis and classification of diabetes mellitus. Diabetes Care 2009;32 (Suppl 1):S62-S67.
7. Economides PA, Caselli A, Tiani E et al. The effects of atorvastatin on endothelial function in diabetic patients and subjects at risk for type 2 diabetes. J Clin Endocrinol Metab 2004;89:740-747. (Pubitemid 38269887)
8. Corretti MC, Anderson TJ, Benjamin EJ et al.; International Brachial Artery Reactivity Task Force. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery:a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 2002;39:257-265 (Pubitemid 34084631)
9. Shrikhande G, Khaodhiar L, Scali S et al. Valsartan improves resting skin blood flow in type 2 diabetic patients and reduces poly(adenosine diphosphate-ribose) polymerase activation. J Vasc Surg 2006;43:760-770; discussion 770-761
10. Arkin JM, Alsdorf R, Bigornia S et al. Relation of cumulative weight burden to vascular endothelial dysfunction in obesity Am J Cardiol 2008;101 98-101 (Pubitemid 350297207)
11. Van Guilder GP, Stauffer BL, Greiner JJ, Desouza CA. Impaired endothelium-dependent vasodilation in overweight and obese adult humans is not limited to muscarinic receptor agonists. Am J Physiol Heart Circ Physiol 2008;294:H1685-H1692. (Pubitemid 351490599)
12. Beckman JA, Goldfine AB, Gordon MB et al. Oral antioxidant therapy improves endothelial function in Type 1 but not Type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol 2003;285:H2392-H2398. (Pubitemid 37443055)
13. Yeh SY, Doupis J, Rahangdale S et al. Total serum bilirubin does not affect vascular reactivity in patients with diabetes. Vasc Med 2009;14:129-136.
14. Veves A, Saouaf R, Donaghue VM et al. Aerobic exercise capacity remains normal despite impaired endothelial function in the micro-and macrocirculation of physically active IDDM patients. Diabetes 1997;46:1846-1852. (Pubitemid 27456420)
15. Caballero AE, Arora S, Saouaf R et al. Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes. Diabetes 1999;48:1856-1862 (Pubitemid 29415208)
16. Yeboah J, Crouse JR, Hsu FC, Burke GL, Herrington DM. Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study Circulation 2007;115:2390-2397 (Pubitemid 46717961)
17. Alvarez GE, Beske SD, Ballard TP, Davy KP. Sympathetic neural activation in visceral obesity Circulation 2002;106:2533-2536. (Pubitemid 35340687)
18. Tentolouris N, Tsigos C, Perea D et al. Differential effects of high-fat and high-carbohydrate isoenergetic meals on cardiac autonomic nervous system activity in lean and obese women. Metab Clin Exp 2003;52 1426-1432 (Pubitemid 37461109)
19. Garcia RV Kraehenmann MA, Bezerra FJ, Mendes CM, Rapp GE. Clinical analysis of the soft tissue integration of non-submerged (ITI) and submerged (3i) implants: a prospective-controlled cohort study Clin Oral Implants Res 2008;19:991-996.
20. Rega G, Kaun C, Demyanets S et al. Vascular endothelial growth factor is induced by the inflammatory cytokines interleukin-6 and oncostatin m in human adipose tissue in vitro and in murine adipose tissue in vivo. Arterioscler Thromb Vasc Biol 2007;27:1587-1595 (Pubitemid 46986114)
21. Cao Y Angiogenesis modulates adipogenesis and obesity J Clin Invest 2007;117:2362-2368. (Pubitemid 47494333)
22. Bao P Kodra A, Tomic-Canic M et al. The role of vascular endothelial growth factor in wound healing. J Surg Res 2009;153:347-358.
23. Xiang GD, Xu L, Zhao LS, Yue L, Hou J. The relationship between plasma osteoprotegerin and endothelium-dependent arterial dilation in type 2 diabetes. Diabetes 2006;55:2126-2131 (Pubitemid 44509988)
24. Jono S, Ikari Y Shioi A et al. Serum osteoprotegerin levels are associated with the presence and severity of coronary artery disease. Circulation 2002;106:1192-1194 (Pubitemid 34988634)
25. Gómez-Ambrosi J, Catalán V Ramírez B et al. Plasma osteopontin levels and expression in adipose tissue are increased in obesity J Clin Endocrinol Metab 2007;92:3719-3727
26. Nomiyama T, Perez-Tilve D, Ogawa D et al. Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice. J Clin Invest 2007;117:2877-2888. (Pubitemid 47529618)
27. Liehn EA, Schober A, Weber C Blockade of keratinocyte-derived chemokine inhibits endothelial recovery and enhances plaque formation after arterial injury in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 2004;24:1891-1896. (Pubitemid 39350309)
28. Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J Clin Invest 1995;95:2409-2415.
29. Steinberg HO, Paradisi G, Cronin J et al. Type II diabetes abrogates sex differences in endothelial function in premenopausal women. Circulation 2000;101:2040-2046. (Pubitemid 30233166)