Channel properties of the translocator domain of the autotransporter Hbp of Escherichia coli

Molecular Membrane Biology

Volumn 28, Issue 3, 2011, Pages 158-170

  Roussel Jazédé, Virginie ^a   Van Gelder, Patrick ^b   Sijbrandi, Robert ^c   Rutten, Lucy ^a,d   Otto, Ben R ^c   Luirink, Joen ^c   Gros, Piet ^d   Tommassen, Jan ^a   Van Ulsen, Peter ^a,c  

^a UTRECHT UNIVERSITY   (Netherlands)

^b FREE UNIVERSITY OF BRUSSELS   (Belgium)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Autotransporter; pore activity; translocator domain

Indexed keywords

BACTERIAL PROTEIN; CARRIER PROTEIN; IMMUNOGLOBULIN A; LIPOSOME; PROTEIN HBP; PROTEIN NALP; UNCLASSIFIED DRUG; HEMOGLOBIN PROTEASE HBP; IGA SPECIFIC SERINE ENDOPEPTIDASE; IGA-SPECIFIC SERINE ENDOPEPTIDASE; PROTEINASE; SERINE PROTEINASE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; ESCHERICHIA COLI; IN VITRO STUDY; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; ENZYMOLOGY; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN TERTIARY STRUCTURE; SPECTROFLUOROMETRY;

ESCHERICHIA COLI; NEGIBACTERIA; NEISSERIA GONORRHOEAE; NEISSERIA MENINGITIDIS;

CIRCULAR DICHROISM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPEPTIDASES; ESCHERICHIA COLI; LIPOSOMES; NEISSERIA MENINGITIDIS; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SERINE ENDOPEPTIDASES; SPECTROMETRY, FLUORESCENCE;

EID: 79953186087     PISSN: 09687688     EISSN: 14645203     Source Type: Journal    
DOI: 10.3109/09687688.2010.550328     Document Type: Article

References (31)

1. Barnard TJ, Dautin N, Lukacic P, Bernstein HD, Buchanan SK. 2007. Autotransporter structure reveals intra-barrel cleavage followed by conformational changes. Nat Struct Mol Biol 14:1214-1220. (Pubitemid 350223331)
2. Bryson K, McGuffin LJ, Marsden RL, Ward JJ, Sodhi JS, Jones DT. 2005. Protein structure prediction servers at University College London. Nucl Acids Res 33(Web Server issue): W36-38. Available from: http://bioinf.cs.ucl.ac.uk/ psipred/. (Pubitemid 44529876)
3. Dautin N, Bernstein HD. 2007. Protein secretion in Gram-negative bacteria via the autotransporter pathway. Annu Rev Microbiol 61:89-112. (Pubitemid 350058201)
4. Dautin N, Barnard TJ, Anderson DE, Bernstein HD. 2007. Cleavage of a bacterial autotransporter by an evolu-tionarily convergent autocatalytic mechanism. EMBO J 26:1942-1952. (Pubitemid 46624049)
5. Dé E, Saint N, Glinel K, Meli AC, Levy D, Jacob-Dubuisson F. 2008. Influence of the passenger domain of a model autotran-sporter on the properties of its translocator domain. Mol Membr Biol, 25, 192-202. (Pubitemid 351563943)
6. Emsley P, Charles IG, Fairweather NF, Isaacs NW. 1996. Structure of Bordetella pertussis virulence factor P.69 pertactin. Nature 381:90-92. (Pubitemid 26130010)
7. Ieva R, Skillman KM, Bernstein HD. 2008. Incorporation of a polypeptide segment into the b-domain pore during the assembly of a bacterial autotransporter. Mol Microbiol 67:188-201. (Pubitemid 350231146)
8. Jansen C, Wiese A, Reubsaet L, Dekker N, de Cock H, Seydel U, Tommassen J. 2000. Biochemical and biophysical characterization of in vitro folded outer membrane porin PorA of Neisseria meningitidis. Biochim Biophys Acta 1464:284-298. (Pubitemid 30155886)
9. Jong WSP, ten Hagen-Jongman CM, den Blaauwen T, Slotboom DJ, Tame JRH, Wickström D, de Gier JW, Otto BR, Luirink J. 2007. Limited tolerance towards folded elements during secretion of the autotransporter Hbp. Mol Microbiol 63:1524-1536.
10. Khalid S, Sansom MS. 2006. Molecular dynamics simulations of a bacterial autotransporter: NalP from Neisseria meningitidis. Mol Membr Biol 23:499-508. (Pubitemid 44837735)
11. Klauser T, Kramer J, Otzelberger K, Pohlner J, Meyer TF. 1993. Characterization of the Neisseria Iga b-core. The essential unit for outer membrane targeting and extracellular protein secretion. J Mol Biol 234:579-593. (Pubitemid 24007788)
12. Nakamura K, Mizushima S. 1976. Effects of heating in dodecyl sulfate solution on the conformation and electrophoretic mobility of isolated major outer membrane proteins from Escherichia coli K-12. J Biochem 80:1411-1422. (Pubitemid 8028446)
13. Nikaido H, Nikaido K, Harayama S. 1991. Identification and characterization of porins in Pseudomonas aeruginosa. J Biol Chem 266:770-779. (Pubitemid 21907182)
14. Nikaido H. 2003. Molecular basis of bacterial outer membrane permeability revisited. Microbiol Mol Biol Rev 67:593-656. (Pubitemid 37549772)
15. Oomen CJ, van Ulsen P, Van Gelder P, Feijen M, Tommassen J, Gros P. 2004. Structure of the translocator domain of a bacterial autotransporter. EMBO J 23:1257-1266. (Pubitemid 38524998)
16. Otto BR, van Dooren SSJ, Nuijens JH, Luirink J, Oudega B. 1998. Characterization of a hemoglobin protease secreted by the pathogenic Escherichia coli strain EB1. J Exp Med 188:1091-1103. (Pubitemid 28443333)
17. Otto BR, van Dooren SJ, Dozois CM, Luirink J, Oudega B. 2002. Escherichia coli hemoglobin protease autotransporter contributes to synergistic abscess formation and heme-dependent growth of Bacteroides fragilis. Infect Immun 70: 5-10. (Pubitemid 34028592)
18. Otto BR, Sijbrandi R, Luirink J, Oudega B, Heddle JG, Mizutani K, Park SY, Tame JRH. 2005. Crystal structure of hemoglobin protease, a heme binding autotrans-porter protein from Escherichia coli. J Biol Chem 280: 17339-17345. (Pubitemid 41389203)
19. Pace CN, Scholtz JM. 1997. Measuring the conformational stability of a protein. In: Creighton TE, editor. Protein structure: A practical approach. 2nd ed. New York: Oxford University Press. pp 302-324.
20. Perez-Iratxeta C, Andrade-Navarro MA. 2008. K2D2: Estimation of protein secondary structure from circular dichroism spectra. BMC Struct Biol 8:25. Available from http://www. embl.de/∼andrade/k2d/.
21. Pohlner J, Halter R, Beyreuther K, Meyer TF. 1987. Gene structure and extracellular secretion of Neisseria gonorrhoeae IgA protease. Nature 325:458-462. (Pubitemid 17056417)
22. Rutten L, Mannie JP, Stead CM, Raetz CRH, Reynolds CM, Bonvin AM, Tommassen JP, Egmond MR, Trent MS, Gros P. 2009. Active-site architecture and catalytic mechanism of the lipid A deacylase LpxR of Salmonella typhimurium. Proc Natl Acad Sci USA 106:1960-1964.
23. Sauri A, Soprova Z, Wickström D, de Gier JW, Van der Schors RC, Smit AB, Jong WSP, Luirink J. 2009. The Bam (Omp85) complex is involved in secretion of the autotransporter haemoglobin protease. Microbiology 155:3982-3991.
24. Sen K, Hellman J, Nikaido H. 1988. Porin channels in intact cells of Escherichia coli are not affected by Donnan potentials across the outer membrane. J Biol Chem 263:1182-1187. (Pubitemid 18039918)
25. Shannon JL, Fernandez RC 1999. The C-terminal domain of the Bordetella pertussis autotransporter BrkA forms a pore in lipid bilayer membranes. J Bacteriol 181 5838-5842. (Pubitemid 29437158)
26. Stock JB, Rauch B, Roseman S. 1977. Periplasmic space in Salmonella typhimurium and Escherichia coli. J Biol Chem 252:7850-7861. (Pubitemid 8211043)
27. Studier FW, Rosenberg AH, Dunn JJ, Dubbendorff JW. 1990. Use of T7 RNA polymerase to direct expression of cloned genes. Methods Enzymol 185:60-89. (Pubitemid 20219811)
28. Tajima N, Kawai F, Park SY, Tame JRH. 2010. A novel intein-like autoproteolytic mechanism in autotransporter proteins. J Mol Biol 402:645-656.
29. Van Gelder P, Dumas F, Rosenbusch JP, Winterhalter M. 2000. Oriented channels reveal asymmetric energy barriers for sugar translocation through maltoporin of Escherichia coli. Eur J Biochem 267:79-84. (Pubitemid 30029740)
30. van Ulsen P, van Alphen L, ten Hove J, Fransen F, van der Ley P, Tommassen J. 2003. A Neisserial autotransporter NalP modulating the processing of other autotransporters. Mol Microbiol 50:1017-1030. (Pubitemid 37372260)
31. Veiga E, Sugawara E, Nikaido H, de Lorenzo V, Fernadez LA. 2002. Export of autotransported proteins proceeds through an oligomeric ring shaped by C-terminal domains. EMBO J 21:2122-2131. (Pubitemid 34516771)