Impact of autosomal recessive juvenile parkinson's disease mutations on the structure and interactions of the parkin ubiquitin-like domain

Biochemistry

Volumn 50, Issue 13, 2011, Pages 2603-2610

  Safadi, Susan S ^a   Barber, Kathryn R ^a   Shaw, Gary S ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MULTI DOMAINS; N-TERMINALS; NMR SPECTROSCOPY; PARKINSON'S DISEASE; REGULATORY SUBUNITS; STRUCTURAL EFFECT; UBIQUITIN LIGASES; UBIQUITIN-LIKE;

GENES; NEURODEGENERATIVE DISEASES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS; THREE DIMENSIONAL;

PARKS;

PARKIN; UBIQUITIN PROTEIN LIGASE E3;

AMINO TERMINAL SEQUENCE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; AUTOSOMAL RECESSIVE JUVENILE PARKINSONISM; CONTROLLED STUDY; GENE; GENE FUNCTION; GENE MUTATION; GENETIC CODE; GENETIC HETEROGENEITY; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARK2 GENE; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE; SOIL AGGREGATION; UBL DOMAIN;

AMINO ACID SUBSTITUTION; CIRCULAR DICHROISM; HUMANS; KINETICS; MUTANT PROTEINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PARKINSONIAN DISORDERS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN DENATURATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN REFOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; PROTEIN UNFOLDING; RECOMBINANT PROTEINS; RNA, RIBOSOMAL; TEMPERATURE; UBIQUITIN-PROTEIN LIGASES;

EID: 79953182301     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200065g     Document Type: Article

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