Escherichia coli W as a new platform strain for the enhanced production of L-Valine by systems metabolic engineering

Biotechnology and Bioengineering

Volumn 108, Issue 5, 2011, Pages 1140-1147

  Park, Jin Hwan ^a   Jang, Yu Sin ^a   Lee, Jeong Wook ^a   Lee, Sang Yup ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Escherichia coli W strain; L valine; L valine tolerance; Metabolic engineering

Indexed keywords

ACETIC ACID PRODUCTIONS; ACETOHYDROXY ACID SYNTHASE; AMINOTRANSFERASE; BIOPRODUCTS; BRANCHED CHAIN AMINO ACIDS; CORYNEBACTERIUM GLUTAMICUM; E. COLI; FED-BATCH CULTURES; GENES ENCODING; HIGH CONCENTRATION; L-VALINE; METABOLIC CHARACTERISTICS; METABOLIC ENGINEERING; OVER-EXPRESSION; PYRUVATES; VOLUMETRIC PRODUCTIVITY;

ACETIC ACID; BATCH CELL CULTURE; BIOCHEMISTRY; BIOSYNTHESIS; ENCODING (SYMBOLS); ESCHERICHIA COLI; GENE EXPRESSION; METABOLISM;

AMINO ACIDS;

ACETIC ACID; ACETOLACTATE SYNTHASE; BACTERIAL DNA; BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE; KETOL ACID REDUCTOISOMERASE; PYRUVIC ACID; VALINE;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM CULTURE; CELL GROWTH; CONTROLLED STUDY; ESCHERICHIA COLI; ESCHERICHIA COLI W; FED BATCH CULTURE; FED BATCH FERMENTATION; GENE AMPLIFICATION; GENE DELETION; GENE OVEREXPRESSION; ILVA GENE; ILVG GENE; LACI GENE; LRP GENE; METABOLIC ENGINEERING; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PLASMID; PROMOTER REGION; PROTEIN SYNTHESIS; SEQUENCE ALIGNMENT; YGAZH GENE;

BASE SEQUENCE; DNA PRIMERS; ESCHERICHIA COLI; GENETIC ENGINEERING; PROMOTER REGIONS, GENETIC; VALINE;

CORYNEBACTERIUM GLUTAMICUM; ESCHERICHIA COLI; ESCHERICHIA COLI K12;

EID: 79953162662     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23044     Document Type: Article

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