Nanoscale nuclear architecture for cancer diagnosis beyond pathology via spatial-domain low-coherence quantitative phase microscopy

Journal of Biomedical Optics

Volumn 15, Issue 6, 2010, Pages

  Wang, Pin ^a   Bista, Rajan K ^a   Khalbuss, Walid E ^b   Qiu, Wei ^b   Uttam, Shikhar ^a   Staton, Kevin ^a   Zhang, Lin ^c   Brentnall, Teresa A ^d   Brand, Randall E ^a   Liu, Yang ^a,e  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e NONE   (United States)

Author keywords

cancer diagnosis; pathology; quantitative phase microscopy

Indexed keywords

ANIMAL MODEL; CANCER DIAGNOSIS; CANCEROUS CELLS; CELL NUCLEUS; CLINICAL SETTINGS; COLORECTAL CANCER; EARLY DETECTION; HUMAN CELLS; IN-SITU; LOW-COHERENCE; MICROSCOPY TECHNIQUE; MOUSE MODELS; NANO SCALE; NOVEL METHODS; NUCLEAR ARCHITECTURE; PROOF OF CONCEPT; QUANTITATIVE ANALYSIS; QUANTITATIVE INFORMATION; QUANTITATIVE PHASE MICROSCOPIES; QUANTITATIVE PHASE MICROSCOPY; TECHNICAL DIFFICULTIES; TISSUE SAMPLES;

ARCHITECTURE; CELLS; CHEMICAL DETECTION; CYTOLOGY; NANOSTRUCTURED MATERIALS; NANOTECHNOLOGY; OPTICAL MICROSCOPY; PATHOLOGY; TISSUE;

DISEASES;

ANIMALIA;

ANIMAL; ARTICLE; C57BL MOUSE; CELL NUCLEUS; COLORECTAL TUMOR; EQUIPMENT; EQUIPMENT DESIGN; HUMAN; INSTRUMENTATION; MOUSE; NANOTECHNOLOGY; OPTICAL COHERENCE TOMOGRAPHY; PATHOLOGY; PHASE CONTRAST MICROSCOPY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL NUCLEUS; COLORECTAL NEOPLASMS; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; HUMANS; MICE; MICE, INBRED C57BL; MICROSCOPY, PHASE-CONTRAST; NANOTECHNOLOGY; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 79953111043     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3523618     Document Type: Conference Paper

References (21)

1. J. A. Nickerson, Nuclear dreams: the malignant alteration of nuclear architecture., J. Cell. Biochem. 70 (2), 172-180 (1998). 10.1002/(SICI)1097- 4644(19980801)70:2 172::AID-JCB3 3.0.CO;2-L (Pubitemid 28308926)
2. D. Zink, A. H. Fischer, and J. A. Nickerson, Nuclear structure in cancer cells., Nature Rev. Cancer 4 (9), 677-687 (2004). 10.1038/nrc1430 (Pubitemid 39215066)
3. J. C. E. Underwood and J. Crocker, Pathology of the Nucleus, Springer-Verlag, Berlin; New York (1990).
4. B. R. Konety and R. H. Getzenberg, Nuclear structural proteins as biomarkers of cancer., J. Cell. Biochem. Suppl. 32-33, 183-191 (1999). 10.1002/(SICI)1097-4644(1999)75:32+ 183::AID-JCB22 3.0.CO;2-A (Pubitemid 30041825)
5. D. A. Ahlquist, Molecular detection of colorectal neoplasia., Gastroenterology 138 (6), 2127-2139 (2010). 10.1053/j.gastro.2010.01.055
6. P. Ferraro, D. Alferi, S. De Nicola, L. De Petrocellis, A. Finizio, and G. Pierattini, Quantitative phase-contrast microscopy by a lateral shear approach to digital holographic image reconstruction., Opt. Lett. 31 (10), 1405-1407 (2006). 10.1364/OL.31.001405 (Pubitemid 44014450)
7. C. Joo, T. Akkin, B. Cense, B. H. Park, and J. F. de Boer, Spectral-domain optical coherence phase microscopy for quantitative phase-contrast imaging., Opt. Lett. 30 (16), 2131-2133 (2005). 10.1364/OL.30.002131 (Pubitemid 41251418)
8. C. G. Rylander, D. P. Dave, T. Akkin, T. E. Milner, K. R. Diller, and A. J. Welch, Quantitative phase-contrast imaging of cells with phase-sensitive optical coherence microscopy., Opt. Lett. 29 (13), 1509-1511 (2004). 10.1364/OL.29.001509
9. N. T. Shaked, M. T. Rinehart, and A. Wax, Dual-interference-channel quantitative-phase microscopy of live cell dynamics., Opt. Lett. 34 (6), 767-769 (2009). 10.1364/OL.34.000767
10. J. Zhang, B. Rao, L. Yu, and Z. Chen, High-dynamic-range quantitative phase imaging with spectral domain phase microscopy., Opt. Lett. 34 (21), 3442-3444 (2009). 10.1364/OL.34.003442
11. G. Popescu, T. Ikeda, R. R. Dasari, and M. S. Feld, Diffraction phase microscopy for quantifying cell structure and dynamics., Opt. Lett. 31 (6), 775-777 (2006). 10.1364/OL.31.000775
12. M. V. Sarunic, S. Weinberg, and J. A. Izatt, Full-field swept-source phase microscopy., Opt. Lett. 31 (10), 1462-1464 (2006). 10.1364/OL.31.001462 (Pubitemid 44014469)
13. A. Barty, K. A. Nugent, D. Paganin, and A. Roberts, Quantitative optical phase microscopy., Opt. Lett. 23 (11), 817-819 (1998). 10.1364/OL.23.000817 (Pubitemid 128590524)
14. P. Wang, R. Bista, R. Bhargava, R. E. Brand, and Y. Liu, Spatial-domain low-coherence quantitative phase microscopy for cancer diagnosis., Opt. Lett. 35 (17), 2840-2842 (2010). 10.1364/OL.35.002840
15. Y. Liu, X. Li, Y. L. Kim, and V. Backman, Elastic backscattering spectroscopic microscopy., Opt. Lett. 30 (18), 2445-2447 (2005). 10.1364/OL.30.002445 (Pubitemid 41463515)
16. R. C. Gonzalez, R. E. Woods, and S. L. Eddins, Digital Image Processing Using MATLAB, Pearson/Prentice Hall, Upper Saddle River, NJ (2004).
17. R. Barer and S. Tkaczyk, Refractive index of concentrated protein solutions., Nature 173 (4409), 821-822 (1954). 10.1038/173821b0
18. P. Kékicheff, R. G. Laughlin, and R. L. Munyon, Diffusive interfacial transport: a new approach to concentrated protein solution studies., Langmuir 17 (16), 4693-4696 (2001). 10.1021/la010226v (Pubitemid 35330182)
19. S. R. Orell, G. F. Sterrett, and D. Whitaker, Fine Needle Aspiration Cytology, Elsevier Churchill Livingstone, Edinburgh; New York (2005).
20. A. Sampedro, A. Salas-Bustamante, M. Lopez-Artimez, J. L. Garcia-Muniz, and G. Urdiales, Cell cycle flow cytometric analysis in the diagnosis and management of colorectal carcinoma., Anal. Quant. Cytol. Histol. 21 (4), 347-352 (1999). (Pubitemid 29383453)
21. D. S. Coffey, Self-organization, complexity and chaos: the new biology for medicine., Nature Med. 4 (8), 882-885 (1998). 10.1038/nm0898-882 (Pubitemid 28364016)