Immunosuppressive activity of 8-gingerol on immune responses in mice

Molecules

Volumn 16, Issue 3, 2011, Pages 2636-2645

  Lu, Jing ^a   Guan, Shuang ^a   Shen, Xue ^a   Qian, Wenhui ^a   Huang, Guoren ^a   Deng, Xuming ^a   Xie, Guanghong ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

8 gingerol; Cellular immune; Humoral immune; Immunosuppression

Indexed keywords

8 GINGEROL; 8-GINGEROL; CATECHOL DERIVATIVE; FATTY ALCOHOL; IMMUNOSUPPRESSIVE AGENT;

ANIMAL; ARTICLE; MOUSE;

ANIMALS; CATECHOLS; FATTY ALCOHOLS; IMMUNOSUPPRESSIVE AGENTS; MICE;

EID: 79953103429     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules16032636     Document Type: Article

References (20)

1. Wong, S.H.Y. Therapeutic drug monitoring for immunosuppressants. Clin. Chim. Acta 2001, 313, 241-253. (Pubitemid 33016717)
2. Serkova, N.; Brand, A.; Christians, U.; Leibfritz, D. Evaluation of the effects of immunosuppressants on neuronal and glial cells in vitro by multinuclear magnetic resonance spectroscopy. Biochim. Biophys. Acta 1996, 1314, 93-104. (Pubitemid 26395503)
3. Zhang, D.H.; Marconi. A.; Xu, L.M.; Uzan, G.;Tripterine inhibits the expression of adhesion molecules in activated endothelial cells. J. Leukoc. Biol. 2006, 80, 309-311.
4. Ye, M.; Xie, W.D.; Lei, F.; Meng, Z.; Zhao, Y.N.; Su, H.; Du, L.J. Brazilein, an important immunosuppressive component from Caesalpinia sappanL. Int. Immunopharmacol. 2006, 6, 426-411.
5. Feng, H.; Yamaki, K.; Takano, H.; Inoue, K.; Yanagisawa, R.; Yoshino, S. Effect of sinomenine on collagen-induced arthritis in mice. Autoimmunity 2007, 40, 532-539. (Pubitemid 351233175)
6. Afzal, M.; Al-Hadidi, D.; Menon, M.; Pesek, J.; Dhami, M.S. Ginger: An ethnomedical, chemical and pharmacological review. Drug Metabol. Drug Interac. 2001, 18, 159-190. (Pubitemid 34038460)
7. Wang, W.; Li, C.Y.; Wen, X.D.; Li, P.; Qi, L.W. Simultaneous determination of 6-gingerol, 8- gingerol, 10-gingerol and 6-shogaol in rat plasma by liquid chromatography-mass spectrometry: Application to pharmacokinetics. J. Chromatogr. B 2009, 877, 671-679.
8. Nie, H.; Meng, L.Z.; Zhang, H.; Zhang, J.Y.; Yin, Z.; Huang, X.S. Analysis of anti-platelet aggregation components of Rhizoma Zingiberis using chicken thrombocyte extract and high performance liquid chromatography. Chin. Med. J. (Engl.) 2008, 121, 1226-1229.
9. Nurtjahja-Tjendraputra, E.; Ammit, A.J.; Roufogalis, B.D.; Tran, V.H.; Duke, C.C. Effective antiplatelet and COX-1 enzyme inhibitors from pungent constituents of ginger. Thromb. Res. 2003, 111, 259-265. (Pubitemid 38021945)
10. Ghayur, M.N.; Gilani, A.H.; Afridi, M.B.; Houghton, P.J. Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways. Vascul. Pharmacol. 2005, 43, 234-241. (Pubitemid 41586210)
11. Koh, E.M.; Kim, H.J.; Kim, S.; Choi, W.H.; Choi, Y.H.; Ryu, S.Y.; Kim, Y.S.; Koh, W.S.; Park, S.Y. Moduation of Macrophage Functions by Compounds Isolated from Zingiber officinale. Planta Med. 2009, 75, 148-151.
12. Lantz, R.C.; Chen, G.J.; Sarihan, M.; Solyom, A.M.; Jolad, S.D.; Timmermann, B.N. The effect of extracts from ginger rhizome on inflammatory mediator production. Phytomedicine 2007, 14, 123-128. (Pubitemid 46136942)
13. Abdel-Aziz, H.; Nahrstedt, A.; Petereit, F.; Windeck, T.; Ploch, M.; Verspohl, E.J. 5-HT3 receptor blocking activity of arylalkanes isolated from the rhizome of Zingiber officinale. Planta Med. 2005, 71, 609-616. (Pubitemid 41133069)
14. Cao, Y.G.; Song, Y.; An, N.; Zhou, C.F.; Deng, X.M. The effects of telocinobufagin isolated from Chan Su on the activation and cytokine secretion of immunocytes in vitro. Fund. Clin. Pharmacol. 2009, 23, 457-464.
15. Byun, J.A.; Ryu, M.H.; Lee, J.K. The immunomodulatory effects of 3-monochloro-1, 2- propanediol on murine splenocyte and peritoneal macrophage function in vitro. Toxicol. In Vitro 2006, 20, 272-278. (Pubitemid 43343756)
16. Caballero-Hernandez, D.; Weberb, R.J.; Hicks, M.E.; Tamez-Guerra, R.; Rodriguez-Padilla, C.; Tamez-Guerra, P.; Rice, K.C.; Ananthan, S.; Gomez-Flores, R. Potentiation of rat lymphocyte proliferation by novel non-peptidic synthetic opioids. Int. Immunopharmacol. 2005, 5, 1271-1278. (Pubitemid 40725720)
17. Dearman, R.J.; Caddick, H.; Basketter, D.A.; Kimber, I. Divergent antibody iso-type responses induced inmice by systemic exposure to proteins: A comparison of ovalbumin with bovine serum albumin. Food Chem. Toxicol. 2000, 38, 351-360. (Pubitemid 30155496)
18. Wey, S.P.; Wu, H.Y.; Chang, F.C.; Jan, T.R. Methamphetamine and diazepam suppress antigenspecific cytokine expression and antibody production in ovalbumin-sensitized BALB/c mice. Toxicol. Lett. 2008, 181, 157-162.
19. Shan, X.; Chen, L.; Cao, M.; Xu, L.; Zhang, S. Effects of human soluble BAFF synthesized in Escherichia coli on CD4+ and CD8+ T lymphocytes as well as NK cells in mice. Physiol. Res. Praha. 2006, 55, 301-307.
20. Li, Y.; Li, X.F.; Ma, Y.Y.; Fang, N.; Russe, J.; Ma, D.; Sun, X.R.; Han, X.; Yang, H.S.; Kinuya, S. Changes in the levels of CD4+ and CD8+ T-lymphocytes after strontium-89 chloride therapy for painful bone metastases in patients correlate with treatment efficacy. Cancer Biother. Radiopharm. 2007, 22, 367-373. (Pubitemid 47067894)