Prevalence of neuropsychiatric syndromes in Alzheimer's disease (AD)

Archives of Gerontology and Geriatrics

Volumn 52, Issue 3, 2011, Pages 258-263

  Youn, Jong Chul ^a   Lee, Dong Young ^b   Jhoo, Jin Hyeong ^c   Kim, Ki Woong ^d   Choo, Il Han ^b   Woo, Jong Inn ^b  

^a Kyunggi Provincial Hospital for Elderly   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c Kangwon National University College of Medicine   (South Korea)

^d Seoul National University Bundang Hospital   (South Korea)

Author keywords

Alzheimer's disease; Behavior rating scale for dementia; Comorbidity; Neuropsychiatric symptom; Neuropsychiatric syndrome

Indexed keywords

ABNORMAL BEHAVIOR; ADULT; AGED; AGGRESSION; ALZHEIMER DISEASE; APATHY; ARTICLE; BEHAVIOR RATING SCALE FOR DEMENTIA KOREAN VERSION; CLINICAL DEMENTIA RATING SCALE; COMORBIDITY; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; FEMALE; HUMAN; IRRITABILITY; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; NEUROPSYCHOLOGICAL TEST; ORGANIC PSYCHOSYNDROME; PREVALENCE; PRIORITY JOURNAL; PSYCHOSIS; SYMPTOMATOLOGY;

AGED; AGED, 80 AND OVER; AGGRESSION; ALZHEIMER DISEASE; APATHY; COGNITION DISORDERS; COMORBIDITY; DEPRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PERSISTENT VEGETATIVE STATE; PREVALENCE; PSYCHOTIC DISORDERS; SEVERITY OF ILLNESS INDEX; SYNDROME;

EID: 79953101878     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archger.2010.04.015     Document Type: Article

References (37)

1. Aalten P., Verhey F.R., Boziki M., Bullock R., Byrne E.J., Camus V., Caputo M., Collins D., De Deyn P.P., Elina K., Frisoni G., Girtler N., Holmes C., Hurt C., Marriott A., Mecocci P., Nobili F., Ousset P.J., Reynish E., Salmon E., Tsolaki M., Vellas B., Robert P.H. Neuropsychiatric syndromes in dementia. Results from the European Alzheimer Disease Consortium: Part I. Dement. Geriatr. Cogn. Disord. 2007, 24:457-463.
2. Apostolova L.G., Cummings J.L. Neuropsychiatric manifestations in mild cognitive impairment: a systematic review of the literature. Dement. Geriatr. Cogn. Disord. 2008, 25:115-126.
3. Bassiony M.M., Lyketsos C.G. Delusions and hallucinations in Alzheimer's disease: review of the brain decade. Psychosomatics 2003, 44:388-401.
4. Chen J.C., Borson S., Scanlan J.M. Stage-specific prevalence of behavioral symptoms in Alzheimer's disease in a multi-ethnic community sample. Am. J. Geriatr. Psychiatry 2000, 8:123-133.
5. Craig D., Mirakhur A., Hart D.J., Mcilroy S.P., Passmore A.P. A cross-sectional study of neuropsychiatric symptoms in 435 patients with Alzheimer's disease. Am. J. Geriatr. Psychiatry 2005, 13:460-468.
6. Dechamps A., Jutand M.A., Onifade C., Richard-Harston S., Bourdel-Marchasson I. Co-occurrence of neuropsychiatric syndromes in demented and psychotic institutionalized elderly. Int. J. Geriatr. Psychiatry 2008, 23:1182-1190.
7. Dunkin J.J., Anderson-Hanley C. Dementia caregiver burden: a review of the literature and guidelines for assessment and intervention. Neurology 1998, 51:S53-S60. (discussion S65-S67).
8. Harwood D.G., Ownby R.L., Barker W.W., Duara R. The factor structure of the Cornell Scale for depression in dementia among probable Alzheimer's disease patients. Am. J. Geriatr. Psychiatry 1998, 6:212-220.
9. Hughes C.P., Berg L., Danziger W.L., Coben L.A., Martin R.L. A new clinical scale for the staging of dementia. Br. J. Psychiatry 1982, 140:566-572.
10. Jeste D.V., Wragg R.E., Salmon D.P., Harris M.J., Thal L.J. Cognitive deficits of patients with Alzheimer's disease with and without delusions. Am. J. Psychiatry 1992, 149:184-189.
11. Krueger R.F., Markon K.E. Reinterpreting comorbidity: a model-based approach to understanding and classifying psychopathology. Annu. Rev. Clin. Psychol. 2006, 2:111-133.
12. Lee J.H., Lee K.U., Lee D.Y., Kim K.W., Jhoo J.H., Kim J.H., Lee K.H., Kim S.Y., Han S.H., Woo J.I. Development of the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (CERAD-K): clinical and neuropsychological assessment batteries. J. Gerontol. B: Psychol. Sci. Soc. Sci. 2002, 57:P47-P53.
13. Levy M.L., Miller B.L., Cummings J.L., Fairbanks L.A., Craig A. Alzheimer disease and frontotemporal dementias. Behavioral distinctions. Arch. Neurol. 1996, 53:687-690.
14. Lopez O.L., Becker J.T., Sweet R.A., Klunk W., Kaufer D.I., Saxton J., Habeych M., Dekosky S.T. Psychiatric symptoms vary with the severity of dementia in probable Alzheimer's disease. J. Neuropsychiatry Clin. Neurosci. 2003, 15:346-353.
15. Lyketsos C.G., Steele C., Galik E., Rosenblatt A., Steinberg M., Warren A., Sheppard J.M. Physical aggression in dementia patients and its relationship to depression. Am. J. Psychiatry 1999, 156:66-71.
16. Lyketsos C.G., Steinberg M., Tschanz J.T., Norton M.C., Steffens D.C., Breitner J.C. Mental and behavioral disturbances in dementia: findings from the Cache County Study on memory in aging. Am. J. Psychiatry 2000, 157:708-714.
17. Lyketsos C.G., Breitner J.C., Rabins P.V. An evidence-based proposal for the classification of neuropsychiatric disturbance in Alzheimer's disease. Int. J. Geriatr. Psychiatry 2001, 16:1037-1042.
18. Lyketsos C.G., Sheppard J.M., Steinberg M., Tschanz J.A., Norton M.C., Steffens D.C., Breitner J.C. Neuropsychiatric disturbance in Alzheimer's disease clusters into three groups: the Cache County Study. Int. J. Geriatr. Psychiatry 2001, 16:1043-1053.
19. Lyketsos C.G., Lopez O., Jones B., Fitzpatrick A.L., Breitner J., Dekosky S. Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. J. Am. Med. Assoc. 2002, 288:1475-1483.
20. Mack J.L., Patterson M.B., Tariot P.N. Behavior Rating Scale for dementia: development of test scales and presentation of data for 555 individuals with Alzheimer's disease. J. Geriatr. Psychiatry Neurol. 1999, 12:211-223.
21. McKeith I., Cummings J. Behavioural changes and psychological symptoms in dementia disorders. Lancet Neurol. 2005, 4:735-742.
22. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
23. Mortimer J.A., Ebbitt B., Jun S.P., Finch M.D. Predictors of cognitive and functional progression in patients with probable Alzheimer's disease. Neurology 1992, 42:1689-1696.
24. O'Donnell B.F., Drachman D.A., Barnes H.J., Peterson K.E., Swearer J.M., Lew R.A. Incontinence and troublesome behaviors predict institutionalization in dementia. J. Geriatr. Psychiatry Neurol. 1992, 5:45-52.
25. Perez-Madrinan G., Cook S.E., Saxton J.A., Miyahara S., Lopez O.L., Kaufer D.I., Aizenstein H.J., Dekosky S.T., Sweet R.A. Alzheimer disease with psychosis: excess cognitive impairment is restricted to the misidentification subtype. Am. J. Geriatr. Psychiatry 2004, 12:449-456.
26. Peters K.R., Rockwood K., Black S.E., Bouchard R., Gauthier S., Hogan D., Kertesz A., Loy-English I., Beattie B.L., Sadovnick A.D., Feldman H.H. Characterizing neuropsychiatric symptoms in subjects referred to dementia clinics. Neurology 2006, 66:523-528.
27. Petersen R.C., Smith G.E., Waring S.C., Ivnik R.J., Tangalos E.G., Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch. Neurol. 1999, 56:303-308.
28. Rabins P.V., Mace N.L., Lucas M.J. The impact of dementia on the family. J. Am. Med. Assoc. 1982, 248:333-335.
29. Robert P.H., Verhey F.R., Byrne E.J., Hurt C., De Deyn P.P., Nobili F., Riello R., Rodriguez G., Frisoni G.B., Tsolaki M., Kyriazopoulou N., Bullock R., Burns A., Vellas B. Grouping for behavioral and psychological symptoms in dementia: clinical and biological aspects. Consensus paper of the European Alzheimer disease consortium. Eur. Psychiatry 2005, 20:490-496.
30. Steele C., Rovner B., Chase G.A., Folstein M. Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. Am. J. Psychiatry 1990, 147:1049-1051.
31. Stern Y., Tang M.X., Albert M.S., Brandt J., Jacobs D.M., Bell K., Marder K., Sano M., Devanand D., Albert S.M., Bylsma F., Tsai W.Y. Predicting time to nursing home care and death in individuals with Alzheimer disease. J. Am. Med. Assoc. 1997, 277:806-812.
32. Tariot P.N., Mack J.L., Patterson M.B., Edland S.D., Weiner M.F., Fillenbaum G., Blazina L., Teri L., Rubin E., Mortimer J.A., Stern Y. The Behavior Rating Scale for dementia of the consortium to establish a registry for Alzheimer's Disease. The behavioral pathology committee of the consortium to establish a registry for Alzheimer's Disease. Am. J. Psychiatry 1995, 152:1349-1357.
33. Tatsch M.F., Bottino C.M., Azevedo D., Hototian S.R., Moscoso M.A., Folquitto J.C., Scalco A.Z., Louza M.R. Neuropsychiatric symptoms in Alzheimer disease and cognitively impaired, nondemented elderly from a community-based sample in Brazil: prevalence and relationship with dementia severity. Am. J. Geriatr. Psychiatry 2006, 14:438-445.
34. Tractenberg R.E., Patterson M., Weiner M.F., Teri L., Grundman M., Thomas R.G., Thal L.J. Prevalence of symptoms on the CERAD behavior rating scale for dementia in normal elderly subjects and Alzheimer's disease patients. J. Neuropsychiatry Clin. Neurosci. 2000, 12:472-479.
35. Tractenberg R.E., Weiner M.F., Patterson M.B., Teri L., Thal L.J. Comorbidity of psychopathological domains in community-dwelling persons with Alzheimer's disease. J. Geriatr. Psychiatry Neurol. 2003, 16:94-99.
36. Youn J.C., Lee D.Y., Lee J.H., Kim K.W., Jhoo J.H., Choo I.H., Paek Y.S., Jeon Y.H., Seo K.W., Woo J.I. Development of a Korean version of the behavior rating scale for dementia (BRSD-K). Int. J. Geriatr. Psychiatry 2008, 23:677-684.
37. Zuidema S., Koopmans R., Verhey F. Prevalence and predictors of neuropsychiatric symptoms in cognitively impaired nursing home patients. J. Geriatr. Psychiatry Neurol. 2007, 20:41-49.