Oncogenic Ras scales the ALPS

Blood

Volumn 117, Issue 10, 2011, Pages 2747-2748

  Shannon, Kevin ^a   Li, Qing ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; GUANOSINE TRIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; NOTCH1 RECEPTOR; PROTEIN TYROSINE PHOSPHATASE SHP 2;

AUTOIMMUNE HEMOLYTIC ANEMIA; AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME; HYPERGAMMAGLOBULINEMIA; LYMPHOCYTE PROLIFERATION; LYMPHOID CELL; NONHUMAN; NOTE; ONCOGENE C H RAS; ONCOGENE K RAS; ONCOGENE N RAS; PRIORITY JOURNAL; PROTEIN BINDING; SOMATIC MUTATION;

EID: 79953100933     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-12-320721     Document Type: Note

References (13)

1. Niemela JE, Lu L, Fleisher TA, et al. Somatic KRAS mutations associated with a human nonmalignant syndrome of autoimmunity and abnormal leukocyte homeostasis. Blood. 2011;117(10):2883-2886.
2. Takagi M, Shinoda K, Piao J, et al. Autoimmune lymphoproliferative syndrome - like disease with somatic KRAS mutation. Blood. 2011;117(10):2887- 2890.
3. Oliveira JB, Bidere N, Niemela JE, et al. NRAS mutation causes a human autoimmune lymphoproliferative syndrome. Proc Natl Acad SciU S A. 2007;104(21):8953-8958. (Pubitemid 47175418)
4. Malumbres M, Barbacid M. RAS oncogenes: the first 30 years. Nat Rev Cancer. 2003;3(6):459-465. (Pubitemid 37328850)
5. Van Etten RA, Shannon KM. Focus on myeloproliferative diseases and myelodysplastic syndromes. Cancer Cell. 2004;6(6):547-552.
6. Johnson L, Mercer K, Breenbaum D, et al. Somatic activation of the K-ras oncogene causes early onset lung cancer in mice. Nature. 2001;410(6832):1111- 1116. (Pubitemid 32391044)
7. Braun BS, Tuveson DA, Kong N, et al. Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder. Proc Natl Acad Sci U S A. 2004;101(2):597-602. (Pubitemid 38084682)
8. Sabnis AJ, Cheung LS, Dail M, et al. Oncogenic Kras initiates leukemia in hematopoietic stem cells. PLoS Biol. 2009;7(3):e59.
9. Li Q, Haigis KM, McDaniel A, Harding-Theobald E, Kogan SC, Akagi K, et al. Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus. Blood. 2011;117(6):2022-2032.
10. Oliveira JB, Bleesing JJ, Dianzani U, et al. Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop. Blood. 116(14):e35-e40.
11. Matsuda K, Shimada A, Yoshida N, et al. Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. Blood. 2007;109(12):5477-5480. (Pubitemid 46890572)
12. Schubbert S, Shannon K, Bollag G. Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer. 2007;7(4):295-308.
13. Gutierrez A, Sanda T, Grebliunaite R, et al. High frequency of PTEN, PI3K, andAKTabnormalities in T-cell acute lymphoblastic leukemia. Blood. 2009;114(3):647-650.