EP1-/- mice have enhanced osteoblast differentiation and accelerated fracture repair

Journal of Bone and Mineral Research

Volumn 26, Issue 4, 2011, Pages 792-802

  Zhang, Minjie ^a   Ho, Hsin Chiu ^a   Sheu, Tzong Jen ^a   Breyer, Matthew D ^b   Flick, Lisa M ^a   Jonason, Jennifer H ^a   Awad, Hani A ^a   Schwarz, Edward M ^a   O'Keefe, Regis J ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

chondrocyte; chondrocyte maturation; EP1; fracture healing; mineralization; osteoblasts; osteoclasts; PGE2

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CYCLIC AMP DEPENDENT PROTEIN KINASE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E1 RECEPTOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE RADIOGRAPHY; BONE REMODELING; CALLUS; CARTILAGE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL ISOLATION; CELL MATURATION; CONTROLLED STUDY; FEMUR FRACTURE; FRACTURE HEALING; GENE EXPRESSION; HISTOPATHOLOGY; MESENCHYMAL STEM CELL; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; SIGNAL TRANSDUCTION;

ACID PHOSPHATASE; ALKALINE PHOSPHATASE; ANIMALS; BONE DENSITY; BONY CALLUS; CARTILAGE; CELL DIFFERENTIATION; CELLS, CULTURED; COLLAGEN TYPE I; COLLAGEN TYPE II; COLLAGEN TYPE X; CORE BINDING FACTOR ALPHA 1 SUBUNIT; FEMALE; FEMORAL FRACTURES; FRACTURE HEALING; GENE EXPRESSION; ISOENZYMES; MALE; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOBLASTS; OSTEOCALCIN; OSTEOCLASTS; OSTEOPROTEGERIN; RANK LIGAND; RECEPTORS, PROSTAGLANDIN E, EP1 SUBTYPE; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; TIME FACTORS; TORSION, MECHANICAL; TRANSCRIPTION FACTORS; X-RAY MICROTOMOGRAPHY;

EID: 79953056654     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.272     Document Type: Article

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