-
1
-
-
67649379367
-
Serotonergic drugs and valvular heart disease
-
Rothman RB, Baumann MH, (2009) Serotonergic drugs and valvular heart disease. Expert Opin Drug Saf 8: 317-329.
-
(2009)
Expert Opin Drug Saf
, vol.8
, pp. 317-329
-
-
Rothman, R.B.1
Baumann, M.H.2
-
2
-
-
0033600538
-
Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates: implications for primary pulmonary hypertension Circulation
-
Rothman RB, Ayestas MA, Dersch CM, Baumann MH, (1999) Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates: implications for primary pulmonary hypertension Circulation 100: 869-875.
-
(1999)
, vol.100
, pp. 869-875
-
-
Rothman, R.B.1
Ayestas, M.A.2
Dersch, C.M.3
Baumann, M.H.4
-
3
-
-
9144236521
-
Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release
-
Walther DJ, Peter JU, Winter S, Holtje M, Paulmann N, et al. (2003) Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release. Cell 115: 851-862.
-
(2003)
Cell
, vol.115
, pp. 851-862
-
-
Walther, D.J.1
Peter, J.U.2
Winter, S.3
Holtje, M.4
Paulmann, N.5
-
4
-
-
34047253930
-
Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells
-
Guilluy C, Rolli-Derkinderen M, Tharaux PL, Melino G, Pacaud P, et al. (2007) Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells. J Biol Chem 282: 2918-2928.
-
(2007)
J Biol Chem
, vol.282
, pp. 2918-2928
-
-
Guilluy, C.1
Rolli-Derkinderen, M.2
Tharaux, P.L.3
Melino, G.4
Pacaud, P.5
-
5
-
-
0034080593
-
A role for the serotonin transporter in hypoxia-induced pulmonary hypertension
-
Fanburg BL, Lee SL, (2000) A role for the serotonin transporter in hypoxia-induced pulmonary hypertension. J Clin Invest 105: 1521-1523.
-
(2000)
J Clin Invest
, vol.105
, pp. 1521-1523
-
-
Fanburg, B.L.1
Lee, S.L.2
-
6
-
-
0034096980
-
Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene
-
Eddahibi S, Hanoun N, Lanfumey L, Lesch KP, Raffestin B, et al. (2000) Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene. J Clin Invest 105: 1555-1562.
-
(2000)
J Clin Invest
, vol.105
, pp. 1555-1562
-
-
Eddahibi, S.1
Hanoun, N.2
Lanfumey, L.3
Lesch, K.P.4
Raffestin, B.5
-
7
-
-
0035347399
-
Dexfenfluramine as a mitogen signal via the formation of superoxide anion
-
Lee SL, Wang WW, Fanburg BL, (2001) Dexfenfluramine as a mitogen signal via the formation of superoxide anion. Faseb J 15: 1324-1325.
-
(2001)
Faseb J
, vol.15
, pp. 1324-1325
-
-
Lee, S.L.1
Wang, W.W.2
Fanburg, B.L.3
-
8
-
-
0033774752
-
5-hydroxytryptamine and the pulmonary circulation: receptors, transporters and relevance to pulmonary arterial hypertension
-
MacLean MR, Herve P, Eddahibi S, Adnot S, (2000) 5-hydroxytryptamine and the pulmonary circulation: receptors, transporters and relevance to pulmonary arterial hypertension. Br J Pharmacol 131: 161-168.
-
(2000)
Br J Pharmacol
, vol.131
, pp. 161-168
-
-
MacLean, M.R.1
Herve, P.2
Eddahibi, S.3
Adnot, S.4
-
9
-
-
33745947405
-
Amphetamine analogs increase plasma serotonin: implications for cardiac and pulmonary disease
-
Zolkowska D, Rothman RB, Baumann MH, (2006) Amphetamine analogs increase plasma serotonin: implications for cardiac and pulmonary disease. J Pharmacol Exp Ther 318: 604-610.
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 604-610
-
-
Zolkowska, D.1
Rothman, R.B.2
Baumann, M.H.3
-
10
-
-
38749112529
-
Chronic fenfluramine administration increases plasma serotonin (5-hydroxytryptamine) to nontoxic levels
-
Zolkowska D, Baumann MH, Rothman RB, (2008) Chronic fenfluramine administration increases plasma serotonin (5-hydroxytryptamine) to nontoxic levels. J Pharmacol Exp Ther 324: 791-797.
-
(2008)
J Pharmacol Exp Ther
, vol.324
, pp. 791-797
-
-
Zolkowska, D.1
Baumann, M.H.2
Rothman, R.B.3
-
11
-
-
44649106435
-
Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice
-
Dempsie Y, Morecroft I, Welsh DJ, MacRitchie NA, Herold N, et al. (2008) Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice. Circulation 117: 2928-2937.
-
(2008)
Circulation
, vol.117
, pp. 2928-2937
-
-
Dempsie, Y.1
Morecroft, I.2
Welsh, D.J.3
MacRitchie, N.A.4
Herold, N.5
-
12
-
-
0037414862
-
Synthesis of serotonin by a second tryptophan hydroxylase isoform
-
Walther DJ, Peter JU, Bashammakh S, Hortnagl H, Voits M, et al. (2003) Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science 299: 76.
-
(2003)
Science
, vol.299
, pp. 76
-
-
Walther, D.J.1
Peter, J.U.2
Bashammakh, S.3
Hortnagl, H.4
Voits, M.5
-
13
-
-
0345686723
-
Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function
-
Cote F, Thevenot E, Fligny C, Fromes Y, Darmon M, et al. (2003) Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function. Proc Natl Acad Sci U S A 100: 13525-13530.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 13525-13530
-
-
Cote, F.1
Thevenot, E.2
Fligny, C.3
Fromes, Y.4
Darmon, M.5
-
14
-
-
46749111405
-
Maternal serotonin influences cardiac function in adult offspring
-
Fligny C, Fromes Y, Bonnin P, Darmon M, Bayard E, et al. (2008) Maternal serotonin influences cardiac function in adult offspring. Faseb J 22: 2340-2349.
-
(2008)
Faseb J
, vol.22
, pp. 2340-2349
-
-
Fligny, C.1
Fromes, Y.2
Bonnin, P.3
Darmon, M.4
Bayard, E.5
-
15
-
-
33645666489
-
Platelet-derived serotonin mediates liver regeneration
-
Lesurtel M, Graf R, Aleil B, Walther DJ, Tian Y, et al. (2006) Platelet-derived serotonin mediates liver regeneration. Science 312: 104-107.
-
(2006)
Science
, vol.312
, pp. 104-107
-
-
Lesurtel, M.1
Graf, R.2
Aleil, B.3
Walther, D.J.4
Tian, Y.5
-
16
-
-
41149115441
-
Enhancement of pulmonary vascular remodelling and inflammatory genes with VIP gene deletion
-
Hamidi SA, Prabhakar S, Said SI, (2008) Enhancement of pulmonary vascular remodelling and inflammatory genes with VIP gene deletion. European Respiratory Journal 31: 135-139.
-
(2008)
European Respiratory Journal
, vol.31
, pp. 135-139
-
-
Hamidi, S.A.1
Prabhakar, S.2
Said, S.I.3
-
17
-
-
57049159708
-
Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions
-
West J, Harral J, Lane K, Deng Y, Ickes B, et al. (2008) Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions. Am J Physiol Lung Cell Mol Physiol 295: L744-755.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
West, J.1
Harral, J.2
Lane, K.3
Deng, Y.4
Ickes, B.5
-
18
-
-
58849128218
-
Increased hyaluronic acid content in idiopathic pulmonary arterial hypertension
-
Papakonstantinou E, Kouri FM, Karakiulakis G, Klagas I, Eickelberg O, (2008) Increased hyaluronic acid content in idiopathic pulmonary arterial hypertension. European Respiratory Journal 32: 1504-1512.
-
(2008)
European Respiratory Journal
, vol.32
, pp. 1504-1512
-
-
Papakonstantinou, E.1
Kouri, F.M.2
Karakiulakis, G.3
Klagas, I.4
Eickelberg, O.5
-
19
-
-
67651236363
-
Hypoxia-induced mitogenic factor/FIZZ1 induces intracellular calcium release through the PLC-IP(3) pathway
-
Fan C, Su Q, Li Y, Liang L, Angelini DJ, et al. (2009) Hypoxia-induced mitogenic factor/FIZZ1 induces intracellular calcium release through the PLC-IP(3) pathway. Am J Physiol Lung Cell Mol Physiol 297: L263-270.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
-
-
Fan, C.1
Su, Q.2
Li, Y.3
Liang, L.4
Angelini, D.J.5
-
20
-
-
0029825291
-
Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction
-
Weir EK, Reeve HL, Huang JM, Michelakis E, Nelson DP, et al. (1996) Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction. Circulation 94: 2216-2220.
-
(1996)
Circulation
, vol.94
, pp. 2216-2220
-
-
Weir, E.K.1
Reeve, H.L.2
Huang, J.M.3
Michelakis, E.4
Nelson, D.P.5
-
21
-
-
33749998142
-
Dexfenfluramine does not worsen but moderates progression of chronic hypoxia-induced pulmonary hypertension
-
Rochefort GY, Lemaire MC, Eder V, Hanton G, Hyvelin JM, et al. (2006) Dexfenfluramine does not worsen but moderates progression of chronic hypoxia-induced pulmonary hypertension. European Journal of Pharmacology 550: 149-154.
-
(2006)
European Journal of Pharmacology
, vol.550
, pp. 149-154
-
-
Rochefort, G.Y.1
Lemaire, M.C.2
Eder, V.3
Hanton, G.4
Hyvelin, J.M.5
-
22
-
-
0031956562
-
Effect of Dexfenfluramine Treatment in Rats Exposed to Acute and Chronic Hypoxia
-
Eddahibi S, Raffestin B, Launay JM, Sitbon M, Adnot S, (1998) Effect of Dexfenfluramine Treatment in Rats Exposed to Acute and Chronic Hypoxia. Amer J Respir Crit Care Med 157: 1111-1119.
-
(1998)
Amer J Respir Crit Care Med
, vol.157
, pp. 1111-1119
-
-
Eddahibi, S.1
Raffestin, B.2
Launay, J.M.3
Sitbon, M.4
Adnot, S.5
-
23
-
-
0036799278
-
Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension
-
Launay JM, Herve P, Peoc'h K, Tournois C, Callebert J, et al. (2002) Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension. Nat Med 8: 1129-1135.
-
(2002)
Nat Med
, vol.8
, pp. 1129-1135
-
-
Launay, J.M.1
Herve, P.2
Peoc'h, K.3
Tournois, C.4
Callebert, J.5
-
24
-
-
33744970745
-
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension
-
Guignabert C, Izikki M, Tu LI, Li Z, Zadigue P, et al. (2006) Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension. Circulation Research 98: 1323-1330.
-
(2006)
Circulation Research
, vol.98
, pp. 1323-1330
-
-
Guignabert, C.1
Izikki, M.2
Tu, L.I.3
Li, Z.4
Zadigue, P.5
-
25
-
-
2442519344
-
Overexpression of the 5-hydroxytryptamine transporter gene: effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension
-
MacLean MR, Deuchar GA, Hicks MN, Morecroft I, Shen S, et al. (2004) Overexpression of the 5-hydroxytryptamine transporter gene: effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension. Circulation 109: 2150-2155.
-
(2004)
Circulation
, vol.109
, pp. 2150-2155
-
-
MacLean, M.R.1
Deuchar, G.A.2
Hicks, M.N.3
Morecroft, I.4
Shen, S.5
-
26
-
-
65549142782
-
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of pulmonary hypertension
-
Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Skinner JT, et al. (2009) Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 296: L582-593.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.296
-
-
Angelini, D.J.1
Su, Q.2
Yamaji-Kegan, K.3
Fan, C.4
Skinner, J.T.5
-
27
-
-
18044365419
-
Functional interactions between 5-hydroxytryptamine receptors and the serotonin transporter in pulmonary arteries
-
Morecroft I, Loughlin L, Nilsen M, Colston J, Dempsie Y, et al. (2005) Functional interactions between 5-hydroxytryptamine receptors and the serotonin transporter in pulmonary arteries. J Pharmacol Exp Ther 313: 539-548.
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 539-548
-
-
Morecroft, I.1
Loughlin, L.2
Nilsen, M.3
Colston, J.4
Dempsie, Y.5
-
28
-
-
0025924672
-
Labeling by [3H]1,3-Di(2-tolyl)guanidine of two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel antagonists and pseudoallosteric modulation by σ ligands
-
Rothman RB, Reid AA, Mahboubi A, Kim C-H, de Costa BR, et al. (1991) Labeling by [3H]1,3-Di(2-tolyl)guanidine of two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel antagonists and pseudoallosteric modulation by σ ligands. MolPharmacol 39: 222-232.
-
(1991)
MolPharmacol
, vol.39
, pp. 222-232
-
-
Rothman, R.B.1
Reid, A.A.2
Mahboubi, A.3
Kim, C.-H.4
de Costa, B.R.5
-
29
-
-
41149171125
-
Evidence based selection of housekeeping genes
-
de Jonge HJ, Fehrmann RS, de Bont ES, Hofstra RM, Gerbens F, et al. (2007) Evidence based selection of housekeeping genes. PLoS One 2: e898.
-
(2007)
PLoS One
, vol.2
-
-
de Jonge, H.J.1
Fehrmann, R.S.2
de Bont, E.S.3
Hofstra, R.M.4
Gerbens, F.5
|