Maternal serotonin influences cardiac function in adult offspring

FASEB Journal

Volumn 22, Issue 7, 2008, Pages 2340-2349

  Fligny, Cécile ^a   Fromes, Yves ^b   Bonnin, Philippe ^c   Darmon, Michèle ^b   Bayard, Elisa ^a   Launay, Jean Marie ^d   Côté, Francine ^a   Mallet, Jacques ^a,e   Vodjdani, Guilan ^a,e  

^a CNRS   (France)

^b INSERM   (France)

^c PARIS CARDIOVASCULAR RESEARCH CENTER   (France)

^d HÔPITAL LARIBOISIÈRE   (France)

^e SORBONNE UNIVERSITÉ   (France)

Author keywords

Dilated cardiomyopathy; Heart failure animal model; Maternal effect; Tryptophan hydroxylase 1 invalidated mouse

Indexed keywords

SEROTONIN;

ARTICLE; CARDIOMYOPATHY; DISEASE SEVERITY; ELECTROCARDIOGRAM; HEART FUNCTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE CONTRACTILITY; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; ELECTROCARDIOGRAPHY; EMBRYONIC DEVELOPMENT; FEMALE; HEART; HEART FUNCTION TESTS; HETEROZYGOTE DETECTION; HOMOZYGOTE; MICE; MICE, KNOCKOUT; SEROTONIN; SIGNAL TRANSDUCTION; TRYPTOPHAN HYDROXYLASE;

ANIMALIA; MUS;

EID: 46749111405     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-100743     Document Type: Article

References (46)

1. Rapport, M. M., Green, A. A., and Page, I. H. (1948) Partial purification of the vasoconstrictor in beef serum. J. Biol. Chem. 174, 735-741
2. Rapport, M. M. (1949) Serum vasoconstrictor serotonin. V. The presence of creatinine in the complex: a proposed structure of the vasoconstrictor principle. J. Biol. Chem. 180, 961-969
3. Twarog, B. M., and Page, I. H. (1953) Serotonin content of some mammalian tissues and urine and a method for its determination. Am. J. Physiol. 175, 157-161
4. Côté, F., Thévenot, E., Fligny, C., Fromes, Y., Darmon, M., Ripoche, M. A., Bayard, E., Hanoun, N., Saurini, F., Lechat, P., Dandolo, L., Hamon, M., Mallet, J., and Vodjdani, G. (2003) Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function. Proc. Natl. Acad. Sci. U. S. A. 100, 13525-13530
5. Walther, D. J., Peter, J. U., Bashammakh, S., Hortnagl, H., Voits, M., Fink, H., and Bader, M. (2003) Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science 299, 76
6. Gershon, M. D., Drakontides, A. B., and Ross, L. L. (1965) Serotonin: synthesis and release from the myenteric plexus of the mouse intestine. Science 149, 197-199
7. Gershon, M. D., and Tack, J. (2007) The serotonin signaling system: from basic understanding to drug development for functional GI disorders. Gastroenterology 132, 397-414
8. Da Prada, M., and Picotti, G. B. (1979) Content and subcellular localization of catecholamines and 5-hydroxytryptamine in human and animal blood platelets: monoamine distribution between platelets and plasma. Br. J. Pharmacol. 65, 653-662
9. Watts, S. W. (2005) 5-HT in systemic hypertension: foe, friend or fantasy? Clin. Sci. (Lond.) 108, 399-412
10. Maurer-Spurej, E. (2005) Serotonin reuptake inhibitors and cardiovascular diseases: a platelet connection. Cell. Mol. Life Sci. 62, 159-170
11. Nebigil, C. G., and Maroteaux, L. (2001) A novel role for serotonin in heart. Trends Cardiovasc. Med. 11, 329-335
12. Ullmer, C., Schmuck, K., Kalkman, H. O., and Lubbert, H. (1995) Expression of serotonin receptor mRNAs in blood vessels. FEBS Lett. 370, 215-221
13. Côté, F., Fligny, C., Fromes, Y., Mallet, J., and Vodjdani, G. (2004) Recent advances in understanding serotonin regulation of cardiovascular function. Trends Mol. Med. 10, 232-238
14. Kaumann, A. J., and Levy, F. O. (2006) 5-Hydroxytryptamine receptors in the human cardiovascular system. Pharmacol. Ther. 111, 674-706
15. Villalón, C. M., and Centurión, D. (2007) Cardiovascular responses produced by 5-hydroxytryptamine: a pharmacological update on the receptors/mechanisms involved and therapeutic implications. Naunyn Schmiedebergs Arch. Pharmacol. 376, 45-63
16. 2B receptors in mice leads to abnormal cardiac structure and function. Circulation 103, 2973-2979
17. 2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy. Circulation 107, 3223-3229
18. 2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1β, and tumor necrosis factor-α cytokine production by ventricular fibroblasts. Circulation 110, 969-974
19. 4 mRNA in heart failure. Naunyn Schmiedebergs Arch. Pharmacol. 370, 157-166
20. 4 receptor-mediated inotropic response to serotonin in heart failure. Cardiovasc. Res. 65, 869-878
21. 4 receptors induced in the acute failing heart. Circ. Res. 97, 268-276
22. Côté, F., Fligny, C., Bayard, E., Launay, J. M., Gershon, M. D., Mallet, J., and Vodjdani, G. (2007) Maternal serotonin is crucial for murine embryonic development. Proc. Natl. Acad. Sci. U. S. A. 104, 329-334
23. Mongue-Din, H., Salmon, A., Fiszman, M. Y., and Fromes, Y. (2007) Non-invasive restrained ECG recording in conscious small rodents: a new tool for cardiac electrical activity investigation. Pflügers Arch. 454, 165-171
24. Bonnin, P., Villemain, A., Vincent, F., Debbabi, H., Silvestre, J. S., Contreres, J. O., Levy, B. I., Tobelem, G., and Dupuy, E. (2007) Ultrasonic assessment of hepatic blood flow as a marker of mouse hepatocarcinoma. Ultrasound Med. Biol. 33, 561-570
25. Brouri, F., Findji, L., Mediani, O., Mougenot, N., Hanoun, N., Le Naour, G., Hamon, M., and Lechat, P. (2002) Toxic cardiac effects of catecholamines: role of β-adrenoceptor downregulation. Eur. J. Pharmacol. 456, 69-75
26. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275
27. Sari, Y., and Zhou, F. C. (2003) Serotonin and its transporter on proliferation of fetal heart cells. Int. J. Dev. Neurosci. 21, 417-424
28. 2B receptors in mice. J. Pharmacol. Exp. Ther. 317, 724-731
29. Kereveur, A., Callebert, J., Humbert, M., Hervé, P., Simonneau, G., Launay, J. M., and Drouet, L. (2000) High plasma serotonin levels in primary pulmonary hypertension: effect of long-term epoprostenol (prostacyclin) therapy. Arterioscler. Thromb. Vasc. Biol. 20, 2233-2239
30. Chakraborti, S., Chakraborti, T., and Shaw, G. (2000) β-Adrenergic mechanisms in cardiac diseases: a perspective. Cell. Signal. 12, 499-513
31. Tevaearai, H. T., and Koch, W. J. (2004) Molecular restoration of β-adrenergic receptor signaling improves contractile function of failing hearts. Trends Cardiovasc. Med. 14, 252-256
32. Guilluy, C., Rolli-Derkinderen, M., Tharaux, P. L., Melino, G., Pacaud, P., and Loirand, G. (2006) Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells. J. Biol. Chem. 282, 2918-2928
33. Vialou, V., Balasse, L., Dumas, S., Giros, B., and Gautron, S. (2007) Neurochemical characterization of pathways expressing plasma membrane monoamine transporter in the rat brain. Neuroscience 144, 616-622
34. Hoyer, D., Clarke, D. E., Fozard, J. R., Hartig, P. R., Martin, G. R., Mylecharane, E. J., Saxena, P. R., and Humphrey, P. P. (1994) International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol. Rev. 46, 157-203
35. Hoyer, D., Hannon, J. P., and Martin, G. R. (2002) Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacol. Biochem. Behav. 71, 533-554
36. Hervé, P., Launay, J. M., Scrobohaci, M. L., Brenot, F., Simonneau, G., Petitpretz, P., Poubeau, P., Cerrina, J., Duroux, P., and Drouet, L. (1995) Increased plasma serotonin in primary pulmonary hypertension. Am. J. Med. 99, 249-254
37. Zolkowska, D., Rothman, R. B., and Baumann, M. H. (2006) Amphetamine analogs increase plasma serotonin: implications for cardiac and pulmonary disease. J. Pharmacol. Exp. Ther. 318, 604-610
38. Anderson, G. M. (2007) Measurement of plasma serotonin in autism. Pediatr. Neurol. 36, 138; author reply 138-139
39. Launay, J. M., Hervé, P., Peoc'h, K., Tournois, C., Callebert, J., Nebigil, C. G., Etienne, N., Drouet, L., Humbert, M., Simonneau, G., and Maroteaux, L. (2002) Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension. Nat. Med. 8, 1129-1135
40. Brenner, B., Harney, J. T., Ahmed, B. A., Jeffus, B. C., Unal, R., Mehta, J. L., and Kilic, F. (2007) Plasma serotonin levels and the platelet serotonin transporter. J. Neurochem. 102, 206-215
41. Lechin, F., van der Dijs, B., Lechin, A., Orozco, B., Lechin, M., Baez, S., Rada, I., Leon, G., and Acosta, E. (1994) Plasma neurotransmitters and cortisol in chronic illness: role of stress. J. Med. 25, 181-192
42. Lechin, F., van der Dijs, B., Orozco, B., Lechin, M., and Lechin, A. E. (1996) Increased levels of free serotonin in plasma of symptomatic asthmatic patients. Ann. Allergy Asthma Immunol. 77, 245-253
43. Connors, S. L., Matteson, K. J., Sega, G. A., Lozzio, C. B., Carroll, R. C., and Zimmerman, A. W. (2006) Plasma serotonin in autism. Pediatr. Neurol. 35, 182-186
44. 2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells. Development 124, 1745-1755
45. Nebigil, C. G., Choi, D. S., Dierich, A., Hickel, P., Le Meur, M., Messaddeq, N., Launay, J. M., and Maroteaux, L. (2000) Serotonin 2B receptor is required for heart development. Proc. Natl. Acad. Sci. U. S. A. 97, 9508-9513
46. Chang, A. S., Chang, S. M., Starnes, D. M., Schroeter, S., Bauman, A. L., and Blakely, R. D. (1996) Cloning and expression of the mouse serotonin transporter. Brain Res. Mol. Brain Res. 43, 185-192