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Volumn 24, Issue 2, 2011, Pages 159-164

New and forthcoming anti-epileptic drugs

Author keywords

clinical trials; epilepsy; new anti epileptic drugs

Indexed keywords

ANTICONVULSIVE AGENT; BGG 492; BRIVARACETAM; CARBAMAZEPINE; CARISBAMATE; CLOBAZAM; DEOXYGLUCOSE; ESLICARBAZEPINE ACETATE; ETIRACETAM; GANAXOLONE; HARKOSERIDE; HUPERZINE A; ICA 105665; LAMOTRIGINE; OXCARBAZEPINE; PERAMPANEL; PLACEBO; RETIGABINE; RUFINAMIDE; SODIUM CHANNEL BLOCKING AGENT; STIRIPENTOL; T 2007; TOPIRAMATE; UNCLASSIFIED DRUG; VALPROIC ACID; VALROCEMIDE; YPP 3089;

EID: 79953031818     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/WCO.0b013e32834479a7     Document Type: Article
Times cited : (30)

References (49)
  • 1
    • 77950838484 scopus 로고    scopus 로고
    • Role of eslicarbazepine in the treatment of epilepsy in adult patients with partial-onset seizures
    • Brown ME, El-Mallakh RS. Role of eslicarbazepine in the treatment of epilepsy in adult patients with partial-onset seizures. Ther Clin Risk Manag 2010;6:103-109.
    • (2010) Ther Clin Risk Manag , vol.6 , pp. 103-109
    • Brown, M.E.1    El-Mallakh, R.S.2
  • 2
    • 61849168486 scopus 로고    scopus 로고
    • Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: A randomized, double-blind, placebo-controlled, parallel-group phase III study
    • Elger C, Halasz P, Maia J, et al. Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: a randomized, double-blind, placebo-controlled, parallel-group phase III study. Epilepsia 2009;50:454-463.
    • (2009) Epilepsia , vol.50 , pp. 454-463
    • Elger, C.1    Halasz, P.2    Maia, J.3
  • 3
    • 70349972675 scopus 로고    scopus 로고
    • Efficacy and safety of 800 and 1200mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures
    • Gil-Nagel A, Lopes-Lima J, Almeida L, et al. Efficacy and safety of 800 and 1200mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures. Acta Neurol Scand 2009;120:281-287.
    • (2009) Acta Neurol Scand , vol.120 , pp. 281-287
    • Gil-Nagel, A.1    Lopes-Lima, J.2    Almeida, L.3
  • 4
    • 77951297857 scopus 로고    scopus 로고
    • Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy
    • Ben-Menachem E, Gabbai AA, Hufnagel A, Maia J, et al. Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy. Epilepsy Res 2010;89:278-285.
    • (2010) Epilepsy Res , vol.89 , pp. 278-285
    • Ben-Menachem, E.1    Gabbai, A.A.2    Hufnagel, A.3    Maia, J.4
  • 5
    • 78649248897 scopus 로고    scopus 로고
    • Long-term efficacy and safety of eslicarbazepine acetate: Results of a 1-year open-label extension study in partial-onset seizures in adults with epilepsy
    • Halasz P, Cramer JA, Hodoba D, et al. Long-term efficacy and safety of eslicarbazepine acetate: results of a 1-year open-label extension study in partial-onset seizures in adults with epilepsy. Epilepsia 2010;51:1963-1969.
    • (2010) Epilepsia , vol.51 , pp. 1963-1969
    • Halasz, P.1    Cramer, J.A.2    Hodoba, D.3
  • 6
    • 77952477242 scopus 로고    scopus 로고
    • Pharmacokinetic interaction study between eslicarbazepine acetate and topiramate in healthy subjects
    • Nunes T, Sicard E, Almeida L, et al. Pharmacokinetic interaction study between eslicarbazepine acetate and topiramate in healthy subjects. Curr Med Res Opin 2010;26:1355-1362.
    • (2010) Curr Med Res Opin , vol.26 , pp. 1355-1362
    • Nunes, T.1    Sicard, E.2    Almeida, L.3
  • 7
    • 77952294567 scopus 로고    scopus 로고
    • Effect of eslicarbazepine acetate on the steady-state pharmacokinetics and pharmacodynamics of warfarin in healthy subjects during a three-stage, open-label, multiple-dose, single-period study
    • Vaz-da-SilvaM, Almeida L, FalcaoA, et al. Effect of eslicarbazepine acetate on the steady-state pharmacokinetics and pharmacodynamics of warfarin in healthy subjects during a three-stage, open-label, multiple-dose, single-period study. Clin Ther 2010;32:179-192.
    • (2010) Clin Ther , vol.32 , pp. 179-192
    • Vaz-Da-Silva, M.1    Almeida, L.2    Falcao, A.3
  • 8
    • 77955578218 scopus 로고    scopus 로고
    • Effect of eslicarbazepine acetate and oxcarbazepine on cognition and psychomotor function in healthy volunteers
    • Milovan D, Almeida L, Romach MK, et al. Effect of eslicarbazepine acetate and oxcarbazepine on cognition and psychomotor function in healthy volunteers. Epilepsy Behav 2010;18:366-373.
    • (2010) Epilepsy Behav , vol.18 , pp. 366-373
    • Milovan, D.1    Almeida, L.2    Romach, M.K.3
  • 9
    • 67649388104 scopus 로고    scopus 로고
    • Lacosamide: A new approach to target voltage-gated sodium currents in epileptic disorders
    • Curia G, Biagini G, Perucca E, Avoli M. Lacosamide: a new approach to target voltage-gated sodium currents in epileptic disorders. CNS Drugs 2009;23:555-568.
    • (2009) CNS Drugs , vol.23 , pp. 555-568
    • Curia, G.1    Biagini, G.2    Perucca, E.3    Avoli, M.4
  • 10
    • 77949469954 scopus 로고    scopus 로고
    • Lacosamide as treatment for partial epilepsy: Mechanisms of action, pharmacology, effects, and safety
    • Kellinghaus C. Lacosamide as treatment for partial epilepsy: mechanisms of action, pharmacology, effects, and safety. Ther Clin Risk Manag 2009;5:757-766.
    • (2009) Ther Clin Risk Manag , vol.5 , pp. 757-766
    • Kellinghaus, C.1
  • 11
    • 77955474694 scopus 로고    scopus 로고
    • In silico docking and electrophysiological characterization of lacosamide binding sites on collapsin response mediator protein 2 identifies a pocket important in modulating sodium channel slow inactivation
    • Wang Y, Brittain JM, Jarecki BW, et al. In silico docking and electrophysiological characterization of lacosamide binding sites on collapsin response mediator protein 2 identifies a pocket important in modulating sodium channel slow inactivation. J Biol Chem 2010;285:25296-25307.
    • (2010) J Biol Chem , vol.285 , pp. 25296-25307
    • Wang, Y.1    Brittain, J.M.2    Jarecki, B.W.3
  • 12
    • 77952727105 scopus 로고    scopus 로고
    • Lacosamide: New adjunctive treatment option for partial-onset seizures
    • Chung SS. Lacosamide: new adjunctive treatment option for partial-onset seizures. Expert Opin Pharmacother 2010;11:1595-1602.
    • (2010) Expert Opin Pharmacother , vol.11 , pp. 1595-1602
    • Chung, S.S.1
  • 13
    • 77954907520 scopus 로고    scopus 로고
    • No pharmacokinetic interaction between lacosamide and carbamazepine in healthy volunteers
    • Cawello W, Nickel B, Eggert-Formella A. No pharmacokinetic interaction between lacosamide and carbamazepine in healthy volunteers. J Clin Phar macol 2010;50:459-471.
    • (2010) J Clin Phar Macol , vol.50 , pp. 459-471
    • Cawello, W.1    Nickel, B.2    Eggert-Formella, A.3
  • 14
    • 78649357007 scopus 로고    scopus 로고
    • A pooled analysis of lacosamide clinical trial data grouped by mechanism of action of concomitant antiepileptic drugs
    • Sake JK, Hebert D, Isojarvi J, et al. A pooled analysis of lacosamide clinical trial data grouped by mechanism of action of concomitant antiepileptic drugs. CNS Drugs 2010;24:1055-1068.
    • (2010) CNS Drugs , vol.24 , pp. 1055-1068
    • Sake, J.K.1    Hebert, D.2    Isojarvi, J.3
  • 15
    • 77953033494 scopus 로고    scopus 로고
    • Lacosamide as adjunctive therapy for partial-onset seizures: A randomized controlled trial
    • Chung S, Sperling MR, Biton V, et al. Lacosamide as adjunctive therapy for partial-onset seizures: a randomized controlled trial. Epilepsia 2010;51:958-967.
    • (2010) Epilepsia , vol.51 , pp. 958-967
    • Chung, S.1    Sperling, M.R.2    Biton, V.3
  • 16
    • 77952781301 scopus 로고    scopus 로고
    • Intravenous lacosamide as short-term replacement for oral lacosamide in partial-onset seizures
    • Krauss G, Ben-Menachem E, Mameniskiene R, et al. Intravenous lacosamide as short-term replacement for oral lacosamide in partial-onset seizures. Epilepsia 2010;51:951-957.
    • (2010) Epilepsia , vol.51 , pp. 951-957
    • Krauss, G.1    Ben-Menachem, E.2    Mameniskiene, R.3
  • 17
    • 75649100509 scopus 로고    scopus 로고
    • Successful treatment for refractory convulsive status epilepticus by nonparenteral lacosamide
    • Tilz C, Resch R, Hofer T, Eggers C. Successful treatment for refractory convulsive status epilepticus by nonparenteral lacosamide. Epilepsia 2010;51:316-317.
    • (2010) Epilepsia , vol.51 , pp. 316-317
    • Tilz, C.1    Resch, R.2    Hofer, T.3    Eggers, C.4
  • 18
    • 78650783166 scopus 로고    scopus 로고
    • Efficacy and safety of intravenous lacosamide in refractory nonconvulsive status epilepticus
    • Koubeissi MZ, Mayor CL, Estephan B, et al. Efficacy and safety of intravenous lacosamide in refractory nonconvulsive status epilepticus. Acta Neurol Scand 2011;123:142-146.
    • (2011) Acta Neurol Scand , vol.123 , pp. 142-146
    • Koubeissi, M.Z.1    Mayor, C.L.2    Estephan, B.3
  • 19
    • 78650789188 scopus 로고    scopus 로고
    • Intravenous lacosamide for treatment of status epilepticus
    • Kellinghaus C, Berning S, Immisch I, et al. Intravenous lacosamide for treatment of status epilepticus. Acta Neurol Scand 2011;123:137-141.
    • (2011) Acta Neurol Scand , vol.123 , pp. 137-141
    • Kellinghaus, C.1    Berning, S.2    Immisch, I.3
  • 20
    • 70449533094 scopus 로고    scopus 로고
    • Six months of postmarketing experience with adjunctive lacosamide in patients with pharmacoresistant focal epilepsy at a tertiary epilepsy center in Germany
    • WehnerT, Bauer S, Hamer HM, et al. Six months of postmarketing experience with adjunctive lacosamide in patients with pharmacoresistant focal epilepsy at a tertiary epilepsy center in Germany. Epilepsy Behav 2009;16:423-425.
    • (2009) Epilepsy Behav , vol.16 , pp. 423-425
    • Wehnert Bauer, S.1    Hamer, H.M.2
  • 21
    • 78651251889 scopus 로고    scopus 로고
    • Lacosamide neurotoxicity associated with concomitant use of sodium channel-blocking antiepileptic drugs: A pharmacodynamic interaction?
    • Novy J, Patsalos PN, Sander JW, Sisodiya SM. Lacosamide neurotoxicity associated with concomitant use of sodium channel-blocking antiepileptic drugs: a pharmacodynamic interaction? Epilepsy Behav 2011;20:20-23.
    • (2011) Epilepsy Behav , vol.20 , pp. 20-23
    • Novy, J.1    Patsalos, P.N.2    Sander, J.W.3    Sisodiya, S.M.4
  • 22
    • 78649964704 scopus 로고    scopus 로고
    • Does lacosamide aggravate Lennox-Gastaut syndrome? Report of three consecutive cases
    • Cuzzola A, Ferlazzo E, Italiano D, et al. Does lacosamide aggravate Lennox-Gastaut syndrome? Report of three consecutive cases. Epilepsy Behav 2010;19:650-651.
    • (2010) Epilepsy Behav , vol.19 , pp. 650-651
    • Cuzzola, A.1    Ferlazzo, E.2    Italiano, D.3
  • 23
    • 77954382660 scopus 로고    scopus 로고
    • Atrial flutter/atrial fibrillation associated with lacosamide for partial seizures
    • Degiorgio CM. Atrial flutter/atrial fibrillation associated with lacosamide for partial seizures. Epilepsy Behav 2010;18:322-324.
    • (2010) Epilepsy Behav , vol.18 , pp. 322-324
    • Degiorgio, C.M.1
  • 24
    • 44949184519 scopus 로고    scopus 로고
    • Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome
    • Glauser T, Kluger G, Sachdeo R, et al. Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome. Neurology 2008;70:1950-1958.
    • (2008) Neurology , vol.70 , pp. 1950-1958
    • Glauser, T.1    Kluger, G.2    Sachdeo, R.3
  • 25
    • 77955298453 scopus 로고    scopus 로고
    • Adjunctive rufinamide in Lennox-Gastaut syndrome: A long-term, open-label extension study
    • Kluger G, Glauser T, KraussG, et al. Adjunctive rufinamide in Lennox-Gastaut syndrome: a long-term, open-label extension study. Acta Neurol Scand 2010;122:202-208.
    • (2010) Acta Neurol Scand , vol.122 , pp. 202-208
    • Kluger, G.1    Kraussg, G.T.2
  • 26
    • 77149135718 scopus 로고    scopus 로고
    • The cost effectiveness of rufinamide in the treatment of Lennox-Gastaut syndrome in the UK
    • Benedict A, Verdian L, Maclaine G. The cost effectiveness of rufinamide in the treatment of Lennox-Gastaut syndrome in the UK. Pharmacoeconomics 2010;28:185-199.
    • (2010) Pharmacoeconomics , vol.28 , pp. 185-199
    • Benedict, A.1    Verdian, L.2    MacLaine, G.3
  • 27
    • 78751503816 scopus 로고    scopus 로고
    • Rufinamide in refractory childhood epileptic encephalopathies other than Lennox-Gastaut syndrome
    • Coppola G, Grosso S, Franzoni E, et al. Rufinamide in refractory childhood epileptic encephalopathies other than Lennox-Gastaut syndrome. Eur J Neurol 2010;18:246-251.
    • (2010) Eur J Neurol , vol.18 , pp. 246-251
    • Coppola, G.1    Grosso, S.2    Franzoni, E.3
  • 28
    • 77952240784 scopus 로고    scopus 로고
    • First European long-term experience with the orphan drug rufinamide in childhood-onset refractory epilepsy
    • Kluger G, Haberlandt E, Kurlemann G, et al. First European long-term experience with the orphan drug rufinamide in childhood-onset refractory epilepsy. Epilepsy Behav 2010;17:546-548.
    • (2010) Epilepsy Behav , vol.17 , pp. 546-548
    • Kluger, G.1    Haberlandt, E.2    Kurlemann, G.3
  • 29
    • 77955534377 scopus 로고    scopus 로고
    • Experience with rufinamide in a pediatric population: A single center's experience
    • Vendrame M, LoddenkemperT, Gooty VD, et al. Experience with rufinamide in a pediatric population: a single center's experience. Pediatr Neurol 2010;43:155-158.
    • (2010) Pediatr Neurol , vol.43 , pp. 155-158
    • Vendrame, M.1    Loddenkemper, T.2    Gooty, V.D.3
  • 30
    • 75149122341 scopus 로고    scopus 로고
    • Safety and tolerability of rufinamide in children with epilepsy: A pooled analysis of 7 clinical studies
    • Wheless JW, Conry J, Krauss G, et al. Safety and tolerability of rufinamide in children with epilepsy: a pooled analysis of 7 clinical studies. J Child Neurol 2009;24:1520-1525.
    • (2009) J Child Neurol , vol.24 , pp. 1520-1525
    • Wheless, J.W.1    Conry, J.2    Krauss, G.3
  • 31
    • 76049084221 scopus 로고    scopus 로고
    • A 24-week multicenter, randomized, double-blind, parallel-group, dose-ranging study of rufinamide in adults and adolescents with inadequately controlled partial seizures
    • Elger CE, Stefan H, Mann A, et al. A 24-week multicenter, randomized, double-blind, parallel-group, dose-ranging study of rufinamide in adults and adolescents with inadequately controlled partial seizures. Epilepsy Res 2010;88:255-263.
    • (2010) Epilepsy Res , vol.88 , pp. 255-263
    • Elger, C.E.1    Stefan, H.2    Mann, A.3
  • 32
    • 68149096743 scopus 로고    scopus 로고
    • Rufinamide for the adjunctive treatment of partial seizures in adults and adolescents: A randomized placebo-controlled trial
    • Brodie MJ, Rosenfeld WE, Vazquez B, et al. Rufinamide for the adjunctive treatment of partial seizures in adults and adolescents: a randomized placebo-controlled trial. Epilepsia 2009;50:1899-1909.
    • (2009) Epilepsia , vol.50 , pp. 1899-1909
    • Brodie, M.J.1    Rosenfeld, W.E.2    Vazquez, B.3
  • 33
    • 38649090393 scopus 로고    scopus 로고
    • Severe myoclonic epilepsy in infancy: A systematic review and a meta-analysis of individual patient data
    • KassäB, Chiron C, Augier S, et al. Severe myoclonic epilepsy in infancy: a systematic review and a meta-analysis of individual patient data. Epilepsia 2008;49:343-348.
    • (2008) Epilepsia , Issue.49 , pp. 343-348
    • Kassäb, C.1
  • 34
    • 33846339429 scopus 로고    scopus 로고
    • Stiripentol
    • DOI 10.1016/j.nurt.2006.10.001, PII S1933721306001747, New Antiepileptic Drugs: Discovery, Development, and Update
    • Chiron C. Stiripentol. Neurotherapeutics 2007, 4, 123-125. (Pubitemid 46127461)
    • (2007) Neurotherapeutics , vol.4 , Issue.1 , pp. 123-125
    • Chiron, C.1
  • 35
    • 58049084097 scopus 로고    scopus 로고
    • The anticonvulsant stiripentol acts directly on the GABA(A) receptor as a positive allosteric modulator
    • Fisher JL. The anticonvulsant stiripentol acts directly on the GABA(A) receptor as a positive allosteric modulator. Neuropharmacology 2009;56:190-197.
    • (2009) Neuropharmacology , vol.56 , pp. 190-197
    • Fisher, J.L.1
  • 36
    • 77955058562 scopus 로고    scopus 로고
    • Interactions of stiripentol with clobazam and valproate in the mouse maximal electroshock-induced seizure model
    • Luszczki JJ, Trojnar MK, Ratnaraj N, et al. Interactions of stiripentol with clobazam and valproate in the mouse maximal electroshock-induced seizure model. Epilepsy Res 2010;90:188-198.
    • (2010) Epilepsy Res , vol.90 , pp. 188-198
    • Luszczki, J.J.1    Trojnar, M.K.2    Ratnaraj, N.3
  • 37
    • 70350401140 scopus 로고    scopus 로고
    • Stiripentol open study in Japanese patients with Dravet syndrome
    • Inoue Y, OhtsukaY, Oguni H, et al. Stiripentol open study in Japanese patients with Dravet syndrome. Epilepsia 2009;50:2362-2368.
    • (2009) Epilepsia , vol.50 , pp. 2362-2368
    • Inoue, Y.1    Ohtsukay Oguni, H.2
  • 38
    • 79953056066 scopus 로고    scopus 로고
    • An open-label study of add-on stiripentol in 25 Japanese patients, mostly children, with SMEI
    • An open-label study of add-on stiripentol in 25 Japanese patients, mostly children, with SMEI.
  • 39
    • 72249118204 scopus 로고    scopus 로고
    • Brivaracetam (ucb 34714) inhibits Na(+) current in rat cortical neurons in culture
    • Zona C, Pieri M, Carunchio I, et al. Brivaracetam (ucb 34714) inhibits Na(+) current in rat cortical neurons in culture. Epilepsy Res 2010;88:46-54.
    • (2010) Epilepsy Res , vol.88 , pp. 46-54
    • Zona, C.1    Pieri, M.2    Carunchio, I.3
  • 40
    • 77955452826 scopus 로고    scopus 로고
    • Adjunctive brivaracetam for refractory partial-onset seizures: A randomized, controlled trial
    • French JA, Costantini C, Brodsky A, et al. Adjunctive brivaracetam for refractory partial-onset seizures: a randomized, controlled trial. Neurology 2010;75:519-525.
    • (2010) Neurology , vol.75 , pp. 519-525
    • French, J.A.1    Costantini, C.2    Brodsky, A.3
  • 41
    • 78650178478 scopus 로고    scopus 로고
    • Progress report on new antiepileptic drugs: A summary of the Tenth Eilat Conference (EILAT X)
    • Bialer M, Johannessen SI, Levy RH, et al. Progress report on new antiepileptic drugs: a summary of the Tenth Eilat Conference (EILAT X). Epilepsy Res 2010;92:89-124.
    • (2010) Epilepsy Res , vol.92 , pp. 89-124
    • Bialer, M.1    Johannessen, S.I.2    Levy, R.H.3
  • 42
    • 58149399475 scopus 로고    scopus 로고
    • Randomized, controlled, dose-ranging trial of carisbamate for partial-onset seizures
    • Faught E, Holmes GL, Rosenfeld WE, et al. Randomized, controlled, dose-ranging trial of carisbamate for partial-onset seizures. Neurology 2008;71:1586-1593.
    • (2008) Neurology , vol.71 , pp. 1586-1593
    • Faught, E.1    Holmes, G.L.2    Rosenfeld, W.E.3
  • 43
    • 77749270555 scopus 로고    scopus 로고
    • Carisbamate as adjunctive treatment of partial onset seizures in adults in two randomized, placebo-controlled trials
    • Sperling MR, Greenspan A, Cramer JA, et al. Carisbamate as adjunctive treatment of partial onset seizures in adults in two randomized, placebo-controlled trials. Epilepsia 2010;51:333-343.
    • (2010) Epilepsia , vol.51 , pp. 333-343
    • Sperling, M.R.1    Greenspan, A.2    Cramer, J.A.3
  • 44
    • 57849141134 scopus 로고    scopus 로고
    • Progress report on new antiepileptic drugs: A summary of the Ninth Eilat Conference (EILAT IX)
    • Bialer M, Johannessen SI, Levy RH, et al. Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res 2009;83:1-43.
    • (2009) Epilepsy Res , vol.83 , pp. 1-43
    • Bialer, M.1    Johannessen, S.I.2    Levy, R.H.3
  • 45
    • 77953317302 scopus 로고    scopus 로고
    • Retigabine: The newer potential antiepileptic drug
    • Czuczwar P, Wojtak A, Cioczek-Czuczwar A, et al. Retigabine: the newer potential antiepileptic drug. Pharmacol Rep 2010;62:211-219.
    • (2010) Pharmacol Rep , vol.62 , pp. 211-219
    • Czuczwar, P.1    Wojtak, A.2    Cioczek-Czuczwar, A.3
  • 46
    • 34247252905 scopus 로고    scopus 로고
    • Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures
    • DOI 10.1212/01.wnl.0000259034.45049.00, PII 0000611420070410000009
    • Porter RJ, Partiot A, Sachdeo R, et al. Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures. Neurology 2007;68:1197-1204. (Pubitemid 46608467)
    • (2007) Neurology , vol.68 , Issue.15 , pp. 1197-1204
    • Porter, R.J.1    Partiot, A.2    Sachdeo, R.3    Nohria, V.4    Alves, W.M.5
  • 47
    • 78649984382 scopus 로고    scopus 로고
    • Efficacy and safety of adjunctive ezogabine/(retigabine) in refractory partial epilepsy
    • Brodie MJ, Lerche H, Gil-Nagel A, et al. Efficacy and safety of adjunctive ezogabine/(retigabine) in refractory partial epilepsy. Neurology 2010;75:1817-1824.
    • (2010) Neurology , vol.75 , pp. 1817-1824
    • Brodie, M.J.1    Lerche, H.2    Gil-Nagel, A.3
  • 48
    • 77951297245 scopus 로고    scopus 로고
    • Ganaxolone suppression of behavioral and elec-trographic seizures in the mouse amygdala kindling model
    • Reddy DS, Rogawski MA. Ganaxolone suppression of behavioral and elec-trographic seizures in the mouse amygdala kindling model. Epilepsy Res 2010;89:254-260.
    • (2010) Epilepsy Res , vol.89 , pp. 254-260
    • Reddy, D.S.1    Rogawski, M.A.2
  • 49
    • 77953956916 scopus 로고    scopus 로고
    • Anticonvulsant action of a new analogue of allopregnanolone in immature rats
    • Mares P, Kubova H, Kasal A. Anticonvulsant action of a new analogue of allopregnanolone in immature rats. Physiol Res 2010;59:305-308.
    • (2010) Physiol Res , vol.59 , pp. 305-308
    • Mares, P.1    Kubova, H.2    Kasal, A.3


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