Finite element analysis of the effects of focal adhesion mechanical properties and substrate stiffness on cell migration

Journal of Biomechanics

Volumn 44, Issue 6, 2011, Pages 1046-1050

  Wong, Henry C ^a   Tang, William C ^a  

^a University of California at Irvine   (United States)

Author keywords

Cell ECM interactions; Finite element model; Focal adhesions; Substrate stiffness; Traction

Indexed keywords

BIOLOGICAL PROCESS; BIPHASIC; CANCER DEVELOPMENT; CELL MATRIX INTERACTIONS; CELL MIGRATION; CELL SUBSTRATES; CELL SURFACE RECEPTORS; COMPUTATIONAL MODEL; DECREASING FUNCTIONS; EXTRACELLULAR; EXTRACELLULAR MATRICES; FINITE ELEMENT ANALYSIS; FINITE ELEMENT MODELS; FLAT SUBSTRATES; FOCAL ADHESIONS; FRICTION COEFFICIENTS; INTRACELLULAR STRESS; LIGAND DENSITY; RELATIVE VELOCITY; SIMULATION RESULT; SPECIFIC BINDING; TRACTION; WOUND HEALING;

ADHESION; CELLS; CYTOLOGY; DENSITY (SPECIFIC GRAVITY); DISEASES; ENZYME ACTIVITY; FINITE ELEMENT METHOD; FOCUSING; LIGANDS; MATHEMATICAL MODELS; MECHANICAL PROPERTIES; SHEAR STRESS; STIFFNESS; STIFFNESS MATRIX; SUBSTRATES; TRACTION (FRICTION);

BIOMECHANICS;

ARTICLE; BIOMECHANICS; CELL ADHESION; CELL INTERACTION; CELL MIGRATION; CELL STRESS; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FINITE ELEMENT ANALYSIS; FOCAL ADHESION; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; PRIORITY JOURNAL; RIGIDITY; YOUNG MODULUS;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; FINITE ELEMENT ANALYSIS; FOCAL ADHESIONS; HUMANS; MODELS, BIOLOGICAL;

EID: 79953027119     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2011.02.004     Document Type: Article

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