The Use of Platelet-Rich Plasma in Arthroscopy and Sports Medicine: Optimizing the Healing Environment

Arthroscopy - Journal of Arthroscopic and Related Surgery

Volumn 26, Issue 2, 2010, Pages 269-278

  Lopez Vidriero, Emilio ^a   Goulding, Krista A ^a   Simon, David A ^a   Sanchez, Mikel ^b   Johnson, Donald H ^c  

^a UNIVERSITY OF OTTAWA   (Canada)

^b Clinica La Esperanza   (Spain)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; ARTHROSCOPY; AUTOGRAFT; CHONDROPATHY; HUMAN; LIGAMENT DISEASE; MUSCLE DISEASE; REVIEW; SPORTS MEDICINE; TENDON DISEASE; THROMBOCYTE RICH PLASMA; WOUND HEALING;

ANTERIOR CRUCIATE LIGAMENT; ARTHROSCOPY; BLOOD COAGULATION; BONE DEVELOPMENT; CARTILAGE; HEMOSTASIS; HUMANS; JOINTS; PLATELET-RICH PLASMA; ROTATOR CUFF; SPORTS MEDICINE; TENDON INJURIES; TENDONS; WOUND HEALING;

EID: 75149132015     PISSN: 07498063     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arthro.2009.11.015     Document Type: Review

References (42)

1. Werner S., and Grose R. Regulation of wound healing by growth factors and cytokines. Physiol Rev 83 (2003) 835-870
2. Anitua E., Andia I., Ardanza B., Nurden P., and Nurden A.T. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 91 (2004) 4-15
3. Anitua E., Sanchez M., Nurden A.T., Nurden P., Orive G., and Andia I. New insights into and novel applications for platelet-rich fibrin therapies. Trends Biotechnol 24 (2006) 227-234
4. Anitua E., Sanchez M., Orive G., and Andia I. Shedding light in the controversial terminology for platelet rich products. J Biomed Mater Res A 90 (2009) 1262-1263
5. Wojtowicz A., Chaberek S., Urbanowska E., and Ostrowski K. Comparison of efficiency of platelet rich plasma, hematopoietic stem cells and bone marrow in augmentation of mandibular bone defects. N Y State Dent J 73 (2007) 41-45
6. Cervelli V., Gentile P., and Grimaldi M. Regenerative surgery: Use of fat grafting combined with platelet-rich plasma for chronic lower-extremity ulcers. Aesthetic Plast Surg 33 (2009) 340-345
7. Arnoczky S.P. Biologic adjuncts to connective tissue healing. Can we improve Mother Nature's recipe?. In: Day A.S. (Ed). Las Vegas: AANA specialty day 2009 (2009), AAOS, Las Vegas 101-107
8. Arnoczky S.P., Tarvin G.B., and Marshall J.L. Anterior cruciate ligament replacement using patellar tendon. An evaluation of graft revascularization in the dog. J Bone Joint Surg Am 64 (1982) 217-224
9. Sanchez M., Anitua E., Orive G., Mujika I., and Andia I. Platelet-rich therapies in the treatment of orthopaedic sports injuries. Sports Med 35 (2009) 1-10
10. Anitua E. Plasma rich in growth factors: Preliminary results of use in the preparation of future sites for implants. Int J Oral Maxillofac Implants 14 (1999) 529-535
11. Bielecki T.M., Gazdzik T.S., Arendt J., Szczepanski T., Krol W., and Wielkoszynski T. Antibacterial effect of autologous platelet gel enriched with growth factors and other active substances: An in vitro study. J Bone Joint Surg Br 89 (2007) 417-420
12. Asfaha S., Cenac N., Houle S., et al. Protease-activated receptor-4: A novel mechanism of inflammatory pain modulation. Br J Pharmacol 150 (2007) 176-185
13. Ahmed T.A., Dare E.V., and Hincke M. Fibrin: A versatile scaffold for tissue engineering applications. Tissue Eng Part B Rev 14 (2008) 199-215
14. Weibrich G., Hansen T., Kleis W., Buch R., and Hitzler W.E. Effect of platelet concentration in platelet-rich plasma on peri-implant bone regeneration. Bone 34 (2004) 665-671
15. Tidball J.G. Inflammatory cell response to acute muscle injury. Med Sci Sports Exerc 27 (1995) 1022-1032
16. Anitua E., Sanchez M., Orive G., and Andia I. The potential impact of the preparation rich in growth factors (PRGF) in different medical fields. Biomaterials 28 (2007) 4551-4560
17. Anitua E., Sanchez M., Nurden A.T., et al. Autologous fibrin matrices: A potential source of biological mediators that modulate tendon cell activities. J Biomed Mater Res A 77 (2006) 285-293
18. Sanchez M., Anitua E., Azofra J., Andia I., Padilla S., and Mujika I. Comparison of surgically repaired Achilles tendon tears using platelet-rich fibrin matrices. Am J Sports Med 35 (2007) 245-251
19. Arnoczky S.P., Anderson L., Fanelli G., Ho S., Mishra A., and Sgaglione N. The role of platelet-rich plasma in connective tissue repair. Orthopedics Today 26 (2009) 29. http://www.orthosupersite.com/view.asp?rid=37598 [serial on the Internet]. Available from: www.orthosupersite.com/view.asp?rid=37598. Accessed April 4, 2009
20. Gosen T, Sluimer J. Prospective randomized study on the effect of autologous platelets injection in lateral epicondylitis compared with corticosteroid injection. Poster P25-444. Presented at: 13th Congress of the European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA), Porto, Portugal, May 21-24, 2008.
21. Maniscalco P., Gambera D., Lunati A., et al. The "Cascade" membrane: A new PRP device for tendon ruptures. Description and case report on rotator cuff tendon. Acta Biomed 79 (2008) 223-226
22. Filardo G, Kon E, Della Villa S, Vincentelli F, Fornasari PM, Marcacci M. Use of platelet-rich plasma for the treatment of refractory jumper's knee. Int Orthop in press, available online 31 July, 2009. doi:10.1007/s00264-009-0845-7.
23. Sanchez M, Anitua E, Andia I. Application of autologous growth factors on skeletal muscle healing. Presented at the Second International Conference on Regenerative Medicine, Leipzig, Germany, May 18-20, 2005.
24. Ishida K., Kuroda R., Miwa M., et al. The regenerative effects of platelet-rich plasma on meniscal cells in vitro and its in vivo application with biodegradable gelatin hydrogel. Tissue Eng 13 (2007) 1103-1112
25. Hirahara AM, Yamashiro K, Dunning R. Enhancing SLAP repairs with fibrin-PRP clots. Presented at the 64th Annual Meeting of the Canadian Orthopaedic Association, Whistler, British Columbia, Canada, July 3-6, 2009.
26. Sanchez M., Azofra J., Anitua E., et al. Plasma rich in growth factors to treat an articular cartilage avulsion: A case report. Med Sci Sports Exerc 35 (2003) 1648-1652
27. Sanchez M., Anitua E., Azofra J., Aguirre J.J., and Andia I. Intra-articular injection of an autologous preparation rich in growth factors for the treatment of knee OA: A retrospective cohort study. Clin Exp Rheumatol 26 (2008) 910-913
28. Cugat R. Platelet derived growth factors: Experience in soft tissue injuries and in joint trauma. Presented at the Seventh Biennial International Society of Arthroscopy, Knee Surgery & Orthopaedic Sports Medicine Congress, Osaka, Japan, April 5-9, 2009.
29. Anitua E., Sanchez M., Nurden A.T., et al. Platelet-released growth factors enhance the secretion of hyaluronic acid and induce hepatocyte growth factor production by synovial fibroblasts from arthritic patients. Rheumatology (Oxford) 46 (2007) 1769-1772
30. Saito M., Takahashi K.A., Arai Y., et al. Intraarticular administration of platelet-rich plasma with biodegradable gelatin hydrogel microspheres prevents osteoarthritis progression in the rabbit knee. Clin Exp Rheumatol 27 (2009) 201-207
31. Ekdahl M., Wang J.H., Ronga M., and Fu F.H. Graft healing in anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 16 (2008) 935-947
32. Mehta V., Foster D., Mandala C., and Petsche T. Comparison of revision rates in autograft and allograft anterior cruciate ligament reconstruction. In: Day A.S. (Ed). Las Vegas: AOSSM specialty day 2009 (2009), AAOS, Las Vegas 49
33. Carey J.L., Dunn W.R., Dahn D.L., Zeger S.L., and Spindler K.P. A systematic review of anterior cruciate ligament reconstruction with autograft compared with allograft. J Bone Joint Surg Am 91 (2009) 2242-2250
34. Radice F., Gutierrez V., Ibarra A., and Verdugo A. Arthroscopic, histologic and MRI correlation in the maturation process of the graft in ACL reconstruction in humans. Arthroscopy 14 Suppl 1 (1998) S20
35. Radice F., Yanez R., Gutierrez V., Pinedo M., Rosales J., and Coda J. Uso de concentrado autologo rico en factores de crecimiento en la reconstrucción del LCA. Rev Argent Artrosc 14 (2008) 31-40
36. Silva A., and Sampaio R. Anatomic ACL reconstruction: Does the platelet-rich plasma accelerate tendon healing?. Knee Surg Sports Traumatol Arthrosc 17 (2009) 676-682
37. Anitua E., Sanchez M., Orive G., and Andia I. Delivering growth factors for therapeutics. Trends Pharmacol Sci 29 (2008) 37-41
38. Sanchez M., Azofra J., Aizpurua B., Elorriaga R., Anitua E., and Andia I. Use of autologous plasma rich in growth factors in arthroscopic surgery. Cuad Artrosc 10 (2003) 12-19
39. Murray M.M., Palmer M., Abreu E., Spindler K.P., Zurakowski D., and Fleming B.C. Platelet-rich plasma alone is not sufficient to enhance suture repair of the ACL in skeletally immature animals: An in vivo study. J Orthop Res 27 (2009) 639-645
40. Murray M.M., Spindler K.P., Ballard P., Welch T.P., Zurakowski D., and Nanney L.B. Enhanced histologic repair in a central wound in the anterior cruciate ligament with a collagen-platelet-rich plasma scaffold. J Orthop Res 25 (2007) 1007-1017
41. Murray M.M., Spindler K.P., Abreu E., et al. Collagen-platelet rich plasma hydrogel enhances primary repair of the porcine anterior cruciate ligament. J Orthop Res 25 (2007) 81-91
42. Murray M.M., Spindler K.P., Devin C., et al. Use of a collagen-platelet rich plasma scaffold to stimulate healing of a central defect in the canine ACL. J Orthop Res 24 (2006) 820-830