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Volumn 27, Issue 5, 2011, Pages 619-624

Association between lipid accumulation and the cannabinoid system in Huh7 cells expressing HCV genes

Author keywords

Cannabinoid; Cannabinoid receptor 1; Hepatitis C virus; Huh7; Replicon; Triglyceride

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; ALPHA INTERFERON; CANNABINOID; CANNABINOID 1 RECEPTOR; ENDOCANNABINOID; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4; NONSTRUCTURAL PROTEIN 5A; NONSTRUCTURAL PROTEIN 5B; TRIACYLGLYCEROL;

EID: 79952976755     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.622     Document Type: Article
Times cited : (15)

References (29)
  • 1
    • 63449105700 scopus 로고    scopus 로고
    • Role of cannabinoids in chronic liver diseases
    • Parfieniuk A and Flislak R: Role of cannabinoids in chronic liver diseases. World J Gastroenterol 14: 6109-6114, 2008.
    • (2008) World J Gastroenterol , vol.14 , pp. 6109-6114
    • Parfieniuk, A.1    Flislak, R.2
  • 2
    • 62749121119 scopus 로고    scopus 로고
    • Cannabinoid receptors as novel therapeutic targets for the management of non-alcoholic steatohepatitis
    • Mallat A and Lotersztajn S: Cannabinoid receptors as novel therapeutic targets for the management of non-alcoholic steatohepatitis. Diabetes Metab 34: 680-684, 2008.
    • (2008) Diabetes Metab , vol.34 , pp. 680-684
    • Mallat, A.1    Lotersztajn, S.2
  • 4
    • 77950681221 scopus 로고    scopus 로고
    • Role of cannabinoids in the development of fatty liver (steatosis)
    • Purohit V, Rapaka R and Shurtleff D: Role of cannabinoids in the development of fatty liver (steatosis). AAPS J 12: 233-237, 2010.
    • (2010) AAPS J , vol.12 , pp. 233-237
    • Purohit, V.1    Rapaka, R.2    Shurtleff, D.3
  • 5
    • 45849112141 scopus 로고    scopus 로고
    • Endocannabinoids and liver disease. IV. Endocannabinoid involvement in obesity and hepatic steatosis
    • Kunos G and Osei-Hyiaman D: Endocannabinoids and liver disease. IV. Endocannabinoid involvement in obesity and hepatic steatosis. Am J Physiol Gastrointest Liver Physiol 294: G1101-G1104, 2008.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Kunos, G.1    Osei-Hyiaman, D.2
  • 7
    • 51349153318 scopus 로고    scopus 로고
    • Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice
    • Osei-Hyiaman D, Liu J, Zhou L, et al: Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice. J Clin Invest 118: 3160-3169, 2008.
    • (2008) J Clin Invest , vol.118 , pp. 3160-3169
    • Osei-Hyiaman, D.1    Liu, J.2    Zhou, L.3
  • 8
    • 41149130137 scopus 로고    scopus 로고
    • Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: Pooled 1-year data from the Rimonabant in Obesity (RIO) program
    • Van Gaal L, Pi-Sunyer X, Despres JP, McCarthy C and Scheen A: Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: pooled 1-year data from the Rimonabant in Obesity (RIO) program. Diabetes Care 31 (Suppl. 2): S229-S240, 2008.
    • (2008) Diabetes Care , vol.31 , Issue.SUPPL. 2
    • Van Gaal, L.1    Pi-Sunyer, X.2    Despres, J.P.3    McCarthy, C.4    Scheen, A.5
  • 11
    • 63649155738 scopus 로고    scopus 로고
    • Selective CB1 cannabinoid receptor antagonist, SR141716A, attenuates liver injury induced by Concanavalin A
    • Kojima M, Kato N, Hirano D, Ochi T, Nii A, Shinjo K and Eda H: Selective CB1 cannabinoid receptor antagonist, SR141716A, attenuates liver injury induced by Concanavalin A. Hepatol Res 39: 408-414, 2009.
    • (2009) Hepatol Res , vol.39 , pp. 408-414
    • Kojima, M.1    Kato, N.2    Hirano, D.3    Ochi, T.4    Nii, A.5    Shinjo, K.6    Eda, H.7
  • 13
    • 38349095862 scopus 로고    scopus 로고
    • CB2 receptors as new therapeutic targets for liver diseases
    • Lotersztajn S, Teixeira-Clerc F, Julien B, et al: CB2 receptors as new therapeutic targets for liver diseases. Br J Pharmacol 153: 286-289, 2008.
    • (2008) Br J Pharmacol , vol.153 , pp. 286-289
    • Lotersztajn, S.1    Teixeira-Clerc, F.2    Julien, B.3
  • 14
    • 77956644099 scopus 로고    scopus 로고
    • Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration
    • Teixeria-Clerc F, Belot MP, Manin S, et al: Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration. Hepatology 52: 1046-1059, 2010.
    • (2010) Hepatology , vol.52 , pp. 1046-1059
    • Teixeria-Clerc, F.1    Belot, M.P.2    Manin, S.3
  • 15
    • 23044450214 scopus 로고    scopus 로고
    • Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver
    • DOI 10.1007/s10620-005-2788-1
    • Yamaguchi A, Tazuma S, Nishioka T, Ohishi W, Hyogo H, Nomura S and Chayama K: Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver. Dig Dis Sci 50: 1361-1371, 2005. (Pubitemid 41184770)
    • (2005) Digestive Diseases and Sciences , vol.50 , Issue.7 , pp. 1361-1371
    • Yamaguchi, A.1    Tazuma, S.2    Nishioka, T.3    Ohishi, W.4    Hyogo, H.5    Nomura, S.6    Chayama, K.7
  • 16
    • 33748376920 scopus 로고    scopus 로고
    • Enhancement of de novo fatty acid biosynthesis in hepatic cell line Huh7 expressing hepatitis C virus core protein
    • Fukasawa M, Tanaka Y, Sato S, et al: Enhancement of de novo fatty acid biosynthesis in hepatic cell line Huh7 expressing hepatitis C virus core protein. Biol Pharm Bull 29: 1958-1961, 2006.
    • (2006) Biol Pharm Bull , vol.29 , pp. 1958-1961
    • Fukasawa, M.1    Tanaka, Y.2    Sato, S.3
  • 17
    • 34248671715 scopus 로고    scopus 로고
    • The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype-specific mechanisms
    • DOI 10.1002/hep.21634
    • Pazienza V, Clément S, Pugnale P, Conzelman S, Foti M, Mangia A and Negro F: The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype-specific mechanisms. Hepatology 45: 1164-1171, 2007. (Pubitemid 46775778)
    • (2007) Hepatology , vol.45 , Issue.5 , pp. 1164-1171
    • Pazienza, V.1    Clement, S.2    Pugnale, P.3    Conzelman, S.4    Foti, M.5    Mangia, A.6    Negro, F.7
  • 19
    • 0033061215 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-κB activation
    • Marusawa H, Hijikata M, Chiba T and Shimotohno K: Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-κB activation. J Virol 73: 4713-4720, 1999. (Pubitemid 29246730)
    • (1999) Journal of Virology , vol.73 , Issue.6 , pp. 4713-4720
    • Marusawa, H.1    Hijikata, M.2    Chiba, T.3    Shimotohno, K.4
  • 24
    • 85006592593 scopus 로고    scopus 로고
    • Endocannabinoids and liver disease
    • Mallat A and Lotersztajin S: Endocannabinoids and liver disease. Am J Physiol 294: G9-G12, 2008.
    • (2008) Am J Physiol , vol.294
    • Mallat, A.1    Lotersztajin, S.2
  • 25
    • 39849096123 scopus 로고    scopus 로고
    • Environmental factors as disease accelerators during chronic hepatitis C
    • Mallat A, Hezode C and Lotersztajn S: Environmental factors as disease accelerators during chronic hepatitis C. J Hepatol 48: 657-665, 2008.
    • (2008) J Hepatol , vol.48 , pp. 657-665
    • Mallat, A.1    Hezode, C.2    Lotersztajn, S.3
  • 27
    • 16644390376 scopus 로고    scopus 로고
    • Circulating endogenous cannabinoid anandamide and portal, systemic and renal hemodynamics in cirrhosis
    • Fernandez-Rodriguez CM, Romero J, Petros TJ, et al: Circulating endogenous cannabinoid anandamide and portal, systemic and renal hemodynamics in cirrhosis. Liver Int 24: 477-483, 2004.
    • (2004) Liver Int , vol.24 , pp. 477-483
    • Fernandez-Rodriguez, C.M.1    Romero, J.2    Petros, T.J.3
  • 28
  • 29
    • 33748703859 scopus 로고    scopus 로고
    • The endocannabinoid system as an emerging target of pharmacotherapy
    • DOI 10.1124/pr.58.3.2
    • Pacher P, Bátkai S and Kunos G: The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev 58: 389-462, 2006. (Pubitemid 44394908)
    • (2006) Pharmacological Reviews , vol.58 , Issue.3 , pp. 389-462
    • Pacher, P.1    Batkai, S.2    Kunos, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.