Initiation of HAART during acute simian immunodeficiency virus infection rapidly controls virus replication in the CNS by enhancing immune activity and preserving protective immune responses

Journal of NeuroVirology

Volumn 17, Issue 1, 2011, Pages 120-130

  Graham, David R ^a   Gama, Lucio ^a   Queen, Suzanne E ^a   Li, Ming ^a   Brice, Angela K ^a   Kelly, Kathleen M ^a   Mankowski, Joseph L ^a   Clements, Janice E ^a   Zink, M Christine ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Acute infection; HAART; IFN; Immune activation; Macaque; MxA; SIV

Indexed keywords

ANTIVIRUS AGENT; ATAZANAVIR; GAMMA INTERFERON; L 870812; MYXOVIRUS RESISTANCE PROTEIN A; SAQUINAVIR; TENOFOVIR; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS RNA;

ACUTE SIMIAN IMMUNODEFICIENCY VIRUS INFECTION; ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COUNT; CELL MIGRATION; CEREBROSPINAL FLUID; CONTROLLED STUDY; CYTOKINE RELEASE; GENE EXPRESSION; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; INNATE IMMUNITY; LENTIVIRUS INFECTION; NATURAL KILLER CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS IMMUNITY; VIRUS LOAD; VIRUS REPLICATION;

ACUTE DISEASE; ANIMALS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BRAIN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; DNA, VIRAL; KILLER CELLS, NATURAL; MACACA; REVERSE TRANSCRIPTASE INHIBITORS; RNA, VIRAL; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; VIRAL LOAD; VIRUS REPLICATION;

ANIMALIA; MACACA; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 79952915822     PISSN: 13550284     EISSN: 15382443     Source Type: Journal    
DOI: 10.1007/s13365-010-0005-2     Document Type: Article

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