Impact of intravenous lidocaine on myocardial injury after off-pump coronary artery surgery

British Journal of Anaesthesia

Volumn 106, Issue 4, 2011, Pages 487-493

  Lee, E H ^a   Lee, H M ^a   Chung, C H ^a   Chin, J H ^a   Choi, D K ^a   Chung, H J ^b   Sim, J Y ^a   Choi, I C ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Kwandong University College of Medicine   (South Korea)

Author keywords

anaesthetics local, lidocaine; bypass surgery, coronary artery; heart, ischaemia

Indexed keywords

BIOLOGICAL MARKER; CREATINE KINASE; CREATINE KINASE MB; HEART ENZYME; LIDOCAINE; PLACEBO; TROPONIN I;

ADULT; AGED; ANESTHESIA INDUCTION; ANESTHESIA MECHANISM; AREA UNDER THE CURVE; ARTICLE; ASYSTOLE; BRADYCARDIA; CARDIOVASCULAR EFFECT; CONTINUOUS INFUSION; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DOUBLE BLIND PROCEDURE; DOWN REGULATION; DRUG BLOOD LEVEL; DRUG EFFECT; ENZYME RELEASE; FEMALE; HEART MUSCLE INJURY; HEART PROTECTION; HUMAN; INTENSIVE CARE UNIT; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; OFF PUMP CORONARY SURGERY; PATIENT ASSESSMENT; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; SURGICAL RISK; TREATMENT OUTCOME;

EID: 79952907995     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aeq416     Document Type: Article

References (34)

1. Chowdhury UK, Malik V, Yadav R, et al. Myocardial injury in coronary artery bypass grafting: On-pump versus off-pump comparison by measuring high-sensitivity C-reactive protein, cardiac troponin I, heart-type fatty acid-binding protein, creatine kinase-MB, and myoglobin release. J Thorac Cardiovasc Surg 2008; 135: 1110-19, 1119.e1-10
2. Kwak YL. Reduction of ischemia during off-pump coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth 2005; 19: 667-77 (Pubitemid 41395034)
3. Wang S, Radhakrishnan J, Ayoub IM, Kolarova JD, Taglieri DM, Gazmuri RJ. Limiting sarcolemmal Na+ entry during resuscitation from ventricular fibrillation prevents excess mitochondrial Ca2+ accumulation and attenuates myocardial injury. J Appl Physiol 2007; 103: 55-65 (Pubitemid 47092277)
4. Aldakkak M, Stowe DF, Lesnefsky EJ, Heisner JS, Chen Q, Camara AK. Modulation of mitochondrial bioenergetics in the isolated Guinea pig beating heart by potassium and lidocaine cardioplegia: Implications for cardioprotection. J Cardiovasc Pharmacol 2009; 54: 298-309
5. Prasad A, Stone GW, Holmes DR, Gersh B. Reperfusion injury, microvascular dysfunction, and cardioprotection: The 'dark side' of reperfusion. Circulation 2009; 120: 2105-12
6. Puskas JD, Vinten-Johansen J, Muraki S, Guyton RA. Myocardial protection for off-pump coronary artery bypass surgery. Semin Thorac Cardiovasc Surg 2001; 13: 82-8
7. Paparella D, Cappabianca G, Malvindi P, et al. Myocardial injury after off-pump coronary artery bypass grafting operation. Eur J Cardiothorac Surg 2007; 32: 481-7 (Pubitemid 47223743)
8. Butwell NB, Ramasamy R, Lazar I, Sherry AD, Malloy CR. Effect of lidocaine on contracture, intracellular sodium, and pH in ischemic rat hearts. Am J Physiol 1993; 264: H1884-9 (Pubitemid 23205960)
9. Ebel D, Lipfert P, Frassdorf J, et al. Lidocaine reduces ischaemic but not reperfusion injury in isolated rat heart. Br J Anaesth 2001; 86: 846-52 (Pubitemid 32514900)
10. Hinokiyama K, Hatori N, Ochi M, Maehara T, Tanaka S. Myocardial protective effect of lidocaine during experimental off-pump coronary artery bypass grafting. Ann Thorac Cardiovasc Surg 2003; 9: 36-42
11. Dias RR, Stolf NA, Dalva M, Dias AR, Moreira LF, Oliveira SA. Inclusion of lidocaine in cardioplegic solutions provides additional myocardial protection. J Cardiovasc Surg (Torino) 2004; 45: 551-5 (Pubitemid 41490611)
12. Dobson GP, Jones MW. Adenosine and lidocaine: A new concept in nondepolarizing surgical myocardial arrest, protection, and preservation. J Thorac Cardiovasc Surg 2004; 127: 794-805 (Pubitemid 38316186)
13. Kaczmarek DJ, Herzog C, Larmann J, et al. Lidocaine protects from myocardial damage due to ischemia and reperfusion in mice by its antiapoptotic effects. Anesthesiology 2009; 110: 1041-9
14. Matthews JN, Altman DG, Campbell MJ, Royston P. Analysis of serial measurements in medical research. Br Med J 1990; 300: 230-5
15. Vincent JL, de Mendonca A, Cantraine F, et al. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: Results of a multicenter, prospective study. Working group on 'sepsis-related problems' of the European Society of Intensive Care Medicine. Crit Care Med 1998; 26: 1793-800 (Pubitemid 28527688)
16. Thygesen K, Alpert JS, White HD, et al. Universal definition of myocardial infarction. Circulation 2007; 116: 2634-53 (Pubitemid 350182388)
17. Canyon SJ, Dobson GP. Protection against ventricular arrhythmias and cardiac death using adenosine and lidocaine during regional ischemia in the in vivo rat. Am J Physiol Heart Circ Physiol 2004; 287: H1286-95
18. Canyon SJ, Dobson GP. Pretreatment with an adenosine A1 receptor agonist and lidocaine: A possible alternative to myocardial ischemic preconditioning. J Thorac Cardiovasc Surg 2005; 130: 371-7 (Pubitemid 41074167)
19. Canyon SJ, Dobson GP. The effect of an adenosine and lidocaine intravenous infusion on myocardial high-energy phosphates and pH during regional ischemia in the rat model in vivo. Can J Physiol Pharmacol 2006; 84: 903-12 (Pubitemid 46132215)
20. Rinne T, Kaukinen S. Does lidocaine protect the heart during coronary revascularisation? Acta Anaesthesiol Scand 1998; 42: 936-40 (Pubitemid 28416864)
21. Jin ZX, Zhang SL, Wang XM, et al. The myocardial protective effects of a moderate-potassium adenosine-lidocaine cardioplegia in pediatric cardiac surgery. J Thorac Cardiovasc Surg 2008; 136: 1450-5
22. Suleiman MS, Zacharowski K, Angelini GD. Inflammatory response and cardioprotection during open-heart surgery: The importance of anaesthetics. Br J Pharmacol 2008; 153: 21-33
23. Gunaydin B, Demiryurek AT. Interaction of lidocaine with reactive oxygen and nitrogen species. Eur J Anaesthesiol 2001; 18: 816-22 (Pubitemid 33071096)
24. MacGregor RR, Thorner RE, Wright DM. Lidocaine inhibits granulocyte adherence and prevents granulocyte delivery to inflammatory sites. Blood 1980; 56: 203-9 (Pubitemid 10043418)
25. Cassuto J, Sinclair R, Bonderovic M. Anti-inflammatory properties of local anesthetics and their present and potential clinical implications. Acta Anaesthesiol Scand 2006; 50: 265-82
26. Kaba A, Laurent SR, Detroz BJ, et al. Intravenous lidocaine infusion facilitates acute rehabilitation after laparoscopic colectomy. Anesthesiology 2007; 106: 11-18 (Pubitemid 46035398)
27. Loick HM, Schmidt C, Van Aken H, et al. High thoracic epidural anesthesia, but not clonidine, attenuates the perioperative stress response via sympatholysis and reduces the release of troponin T in patients undergoing coronary artery bypass grafting. Anesth Analg 1999; 88: 701-9 (Pubitemid 29168830)
28. Kuo CP, Jao SW, Chen KM, et al. Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery. Br J Anaesth 2006; 97: 640-6 (Pubitemid 44593858)
29. Lauwick S, Kim do J, Michelagnoli G, et al. Intraoperative infusion of lidocaine reduces postoperative fentanyl requirements in patients undergoing laparoscopic cholecystectomy. Can J Anaesth 2008; 55: 754-60
30. McKay A, Gottschalk A, Ploppa A, Durieux ME, Groves DS. Systemic lidocaine decreased the perioperative opioid analgesic requirements but failed to reduce discharge time after ambulatory surgery. Anesth Analg 2009; 109: 1805-8
31. Lynch C 3rd. Depression of myocardial contractility in vitro by bupivacaine, etidocaine, and lidocaine. Anesth Analg 1986; 65: 551-9 (Pubitemid 16080698)
32. Olschewski A, Schnoebel-Ehehalt R, Li Y, Tang B, Brau ME,Wolff M. Mexiletine and lidocaine suppress the excitability of dorsal horn neurons. Anesth Analg 2009; 109: 258-64
33. Collinsworth KA, Kalman SM, Harrison DC. The clinical pharmacology of lidocaine as an antiarrhythmic drug. Circulation 1974; 50: 1217-30
34. Barthel H, Ebel D, Mullenheim J, Obal D, Preckel B, Schlack W. Effect of lidocaine on ischaemic preconditioning in isolated rat heart. Br J Anaesth 2004; 93: 698-704 (Pubitemid 39445552)