Modulation of mitochondrial bioenergetics in the isolated guinea pig beating heart by potassium and lidocaine cardioplegia: Implications for cardioprotection

Journal of Cardiovascular Pharmacology

Volumn 54, Issue 4, 2009, Pages 298-309

  Aldakkak, Mohammed ^a   Stowe, David F ^a,b,c,d   Lesnefsky, Edward J ^e,f   Heisner, James S ^a   Chen, Qun ^a   Camara, Amadou K S ^a  

^a Departments of Anesthesiology   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d Medical College of Wisconsin and Marquette University   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ischemia reperfusion; Lidocaine; Mitochondrial calcium load; Mitochondrial redox potential, potassium cardioplegia; Reactive oxygen species

Indexed keywords

FLAVINE ADENINE NUCLEOTIDE; LIDOCAINE; POTASSIUM; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RINGER SOLUTION;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOENERGY; CARDIOPLEGIA; CITRIC ACID CYCLE; CONTROLLED STUDY; GUINEA PIG; HEART BEAT; HEART FUNCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HEART PROTECTION; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CALCIUM; CARDIOPLEGIC SOLUTIONS; CARDIOTONIC AGENTS; ENERGY METABOLISM; GUINEA PIGS; HEART ARREST, INDUCED; HEART RATE; LIDOCAINE; MITOCHONDRIA, HEART; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; OXYGEN; PERFUSION; POTASSIUM; REACTIVE OXYGEN SPECIES;

EID: 74949134558     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e3181b2b842     Document Type: Article

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