Activation of Src kinase in platelet-derived growth factor-B-dependent tubular regeneration after acute ischemic renal injury

American Journal of Pathology

Volumn 163, Issue 1, 2003, Pages 277-286

  Takikita Suzuki, Mikiko ^a   Haneda, Masakazu ^a   Sasahara, Masakiyo ^b   Owada, M Koji ^c   Nakagawa, Takahiko ^a   Isono, Motohide ^a   Takikita, Shoichi ^a   Koya, Daisuke ^a   Ogasawara, Kazumasa ^a   Kikkawa, Ryuichi ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

^c KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; TRAPIDIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CLONE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENE LOCATION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KIDNEY DYSFUNCTION; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY TUBULE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REGENERATIVE ABILITY; REPERFUSION; SIGNAL TRANSDUCTION;

EID: 0037631389     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63651-6     Document Type: Article

References (46)

1. Bacallo R, Fine LG: Molecular events in the organization of renal tubular epithelium from nephrogenesis to regeneration. Am J Physiol 1989, 257:F913-F924
2. 35S-(1,2-dichlorovinyl)-L-cysteine nephrotoxicity in vivo and in cultured proximal tubule epithelial cells. Lab Invest 1992, 66:474-484
3. Nakagawa T, Sasahara M, Haneda M, Kataoka H, Nakagawa H, Yagi M, Kikkawa R, Hazama F: Role of PDGF B-chain and PDGF receptors in rat tubular regeneration after acute injury. Am J Pathol 1999, 155:1689-1699
4. Hammerman MR: Growth factors and apoptosis in acute renal injury. Curr Opin Nephrol Hypertens 1998, 7:419-424
5. Homma T, Sakai M, Cheng HF, Yasuda T, Coffey RJ, Harris RC: Induction of heparin-binding epidermal growth factor-like growth factor mRNA in rat kidney after acute injury. J Clin Invest 1995, 96:1018-1025
6. Matejka GL, Jennische D: IGF-I binding, and IGF-I mRNA expression in the post-ischemic regenerating rat kidney. Kidney Int 1992, 42:1113-1123
7. Abboud HE: Role of platelet-derived growth factor in renal injury. Annu Rev Physiol 1995, 57:297-309
8. Shultz PJ, Dicorleto PE, Silver BJ, Abboud HE: Mesangial cells express PDGF mRNA and proliferate in response to PDGF. Am J Physiol 1988, 255:F674-F684
9. Iida H, Seifert R, Alpers CE, Glonwald RGK, Phillips PE, Pritlz P, Goldon K, Gown AM, Ross R, Bowen-Pope DF, Johnson RJ: Platelet-derived growth factor (PDGF) and PDGF receptors are induced in mesangial proliferative nephritis in the rat. Proc Natl Acad Sci USA 1991, 88:6560-6564
10. Barnes JL, Hevey KA: Glomerular mesangial cell migration in response to platelet-derived growth factor. Lab Invest 1990, 62:379-382
11. Fellstrom B, Klareskog L, Heldin CH, Larsson E, Ronnstrand L, Terracio L, Tufveson G, Wahlberg J, Rubin K: Platelet-derived growth factor receptors in the kidney: upregulated expression in inflammation. Kidney Int 1989, 36:859-869
12. Leveen P, Pekny M, Gebre-Medhin S, Swolin B, Larsson E, Betsholz C: Mice deficient for PDGF-B show renal, cardiovascular, and hematological abnormalities. Genes Dev 1994, 8:1875-1887
13. Philippe S: Abnormal kidney development and hematological disorders in PDGF-β receptor mutant mice. Genes Dev 1994, 8:1888-1896
14. Heldin CH: Structural and functional studies on platelet-derived growth factor. EMBO J 1992, 11:4251-4259
15. Sheila M, Brugge T, Brugge JS: Cellular functions regulated by Src family kinases. Annu Rev Cell Dev Biol 1997, 13:513-609
16. Cooper JA, Howell B: The when and how of Src regulation. Cell 1993, 73:1051-1054
17. Cartwright CA, Eckhart W, Simon W, Kaplan PL: Cell transformation by pp 60 c-src mutated in the carboxy-terminal regulatory domain. Cell 1987, 49:83-91
18. Jove R, Kornbluth S, Hanafusa H: Enzymatically inactive p60c-src mutant with altered ATP-binding site is fully phosphorylated in its carboxy-terminal regulatory region. Cell 1987, 50:937-943
19. Kmiecik TE, Shalloway D: Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation. Cell 1987, 49:65-73
20. DeMali KA, Godwin SL, Soltoff SP, Kazlauskas A: Multiple roles for Src in a PDGF-stimulated cell. Exp Cell Res 1999, 253:271-279
21. Kawakatsu H, Sakai T, Takagaki Y, Shinoda Y, Saito M, Owada MK, Yano J: A new monoclonal antibody which selectively recognizes the active form of Src tyrosine kinase. J Biol Chem 1996, 271:5680-5685
22. Liu MW, Roubin GS, Robinson KA, Black AJR, Hearn JA, Siegel RJ, King III SB: Trapidil in preventing restenosis after balloon angioplasty in the artherosclerotic rabbit. Circulation 1990, 81:1089-1093
23. Ohnishi H, Yamaguchi K, Shimada S, Suzuki K, Kumagai A: A new approach to the treatment of atherosclerosis and Trapidil as an antagonist to platelet-derived growth factor. Life Sci 1981, 28:1641-1646
24. Hoshiya M, Midori A: Trapidil inhibits platelet-derived growth factor-stimulated mitogen-activated protein kinase cascade. Hypertension 1998, 31:664-671
25. Gesualdo L, Paolo SD, Ranieri E, Schena FP: Trapidil inhibits human mesangial cell proliferation: effect on PDGF beta-receptor binding and expression. Kidney Int 1994, 46:1002-1009
26. Sharma SK, Babitch JA: Application of Bradford's protein assay to chick brain subcellular fractions. J Biochem Biophys Methods 1980, 2:247-250
27. Wu Y, Ozaki Y, Inoue K, Satoh K, Ohmori T, Yatomi Y, Owada K: Differential activation and redistribution of c-Src and Fyn in platelets, assessed by MoAb specific for C-terminal tyrosine-dephosphorylated c-Src and Fyn. Biochim Biophys Acta 2000, 1497:27-36
28. Nakagawa T, Hayase Y, Sasahara M, Haneda M, Kikkawa R, Higashiyama S, Hazama F: Distribution of heparin-binding EGF-like growth factor and mRNA in the normal rat kidney. Kidney Int 1997, 51:1774-1779
29. Nouwen EJ, Verstrepen WA, Buyssens N, Zhu M-Q, De Broe ME: Hyperplasia, hypertrophy, and phenotypic alterations in the distal nephron after acute proximal tubular injury in the rat. Lab Invest 1994, 70:479-493
30. Vankatachalam M, Bernard D, Donohoe J, Levinsky N: Ischemic damage and repair in the rat proximal tubule Differences among the S1, S2 and S3 segments. Kidney Int 1978, 14:31-49
31. Torhorst J, de Rougement D, Brunner R, Thiel G: Morphology of the renal medulla in ischemic acute renal failure in the rat. Nephron 1982, 31:296-300
32. Sakai T, Kawakatsu H, Fujita M, Yano J, Owada MK: An epitope localized in c-Src negative regulatory domain is a potential marker in early stage of colonic neoplasms. Lab Invest 1998, 78:219-225
33. Yamada T, Aoyama Y, Owada MK, Kawakatsu H, Kitajima Y: Scraped-wounding causes activation and association of c-Src tyrosine kinase with microtubule in cultured keratinocytes. Cell Struct Funct 2000, 25:351-359
34. Zhao Y, Takagawa K, Oya T, Yang H, Gao Z, Kawaguchi M, Ishii Y, Sasaoka T, Owada K, Furuta I, Sasahara M: Active Src expression is induced after rat peripheral nerve injury. Glia 2003, 42:184-193
35. Rodriguez-Fernandes JL, Rozengurt E: Bombesin, bradykinin, vasopressin, and phorbol esters rapidly and transiently activate Src family tyrosine kinases in Swiss 3T3 cells. J Biol Chem 1996, 271:27895-27901
36. Twamley-Stein GM, Pepperkok R, Ansorge W, Courtneidge SA: The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells. Proc Natl Acad Sci USA 1993, 90:7696-7700
37. 2 for fibroblast cell division. Science 1995, 269:1567-1569
38. Taylor SJ, Shalloway D: An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis. Nature 1994, 368:867-871
39. Fumagalli S, Totty NF, Hsuan JJ, Courtneidge SA: A target for Src in mitosis. Nature 1994, 368:871-874
40. Pillay I, Nakano H, Sharma SV: Radicicol inhibits tyrosine phosphorylation of the mitotic Src substrate Sam68 and retards subsequent exit from mitotic Src-transformed cells. Cell Growth Differ 1996, 7:1487-1499
41. Broome MA, Hunter T: Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling. J Biol Chem 1996, 271:16798-16806
42. Witzgall R, Brown D, Schwarz C, Bonventre JV: Localization of proliferating cell nuclear antigen, vimentin, c-fos, and clusterin in the postischemic kidney. J Clin Invest 1994, 93:2175-2188
43. Valgeirsdottir S, Claesson-Welsh L, Bongcam-Rudloff E, Hellman U, Westermark B, Heldin C-H: PDGF induces reorganization of vimentin filaments. J Cell Sci 1998, 111:1973-1980
44. Futamura A, Izumino K, Nakagawa Y, Takata M, Inoue H, Iida H: Effect of the platelet-derived growth factor antagonist Trapidil on mesangial cell proliferation in rats. Nephron 1999, 81:428-433
45. Megan TB, Cooper JA: Regulation, substrates and functions of Src. Biochem Biophys Acta 1996, 1287:121-149
46. Stracke S, Friedlinde E, Daniela RJ, Grunewald RW, Haller H, Keller F, Jehle PM: Differentiating and proliferative effects of HGF in renal proximal tubular cells are mediated via different signaling pathways. Nephrol Dial Transplant 1998, 1113:1398-1405