Amyotrophic lateral sclerosis and frontotemporal dementia (ALS-FTD)

Archives Italiennes de Biologie

Volumn 149, Issue 1, 2011, Pages 39-56

  Zago, S ^a   Poletti, B ^a   Morelli, C ^a   Doretti, A ^a   Silani, V ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

ALS; ALS FTD syndrome; FTD

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BEHAVIOR; COGNITIVE DEFECT; DIAGNOSTIC IMAGING; FRONTOTEMPORAL DEMENTIA; HUMAN; NEUROPHYSIOLOGY; NEUROPSYCHOLOGICAL TEST;

AMYOTROPHIC LATERAL SCLEROSIS; BEHAVIORAL SYMPTOMS; COGNITION DISORDERS; DIAGNOSTIC IMAGING; FRONTOTEMPORAL DEMENTIA; HUMANS; NEUROPHYSIOLOGY; NEUROPSYCHOLOGICAL TESTS;

EID: 79952839372     PISSN: 00039829     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (134)

1. Abrahams S., Goldstein L.H., Al-Chalabi A., Pickering A., Morris R.G., Passingham R.E., Brooks D.J., Leigh P.N. Relation between cognitive dysfunction and pseudobulbar palsy in amyotrophic lateral sclerosis. J. Neurol. Neurosurg. Psychiatry, 62: 464-472, 1997. (Pubitemid 27237054)
2. Abrahams S., Leigh P.N., Harvey A., Vythelingum G.N., Grisé D., Goldstein L.H. Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS). Neuropsychologia, 38: 734-747, 2000. (Pubitemid 30109452)
3. Abrahams S., Goldstein L.H., Simmons A., Brammer M., Williams S.C., Giampietro V., Leigh P.N. Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study. Brain, 127: 1507-1517, 2004. (Pubitemid 38899404)
4. Abrahams S., Leigh P.N., Goldstein L.H. Cognitive change in ALS: a prospective study. Neurology, 64:1222-1226, 2005.
5. Agosta F., Chiò A., Cosottini M., De Stefano N., Falini A., Mascalchi M., Rocca M.A., Silani V., Tedeschi G., Filippi M. The Present and the Future of Neuroimaging in Amyotrophic Lateral Sclerosis. Am. J. Neuroradiol., 31: 1769-1777, 2010.
6. Anneser J.H.H., Fox R.J., Borasio G.D. Inappropiate sexual behavioural in a case of ALS and FTD: successful treatment with Sertraline. Amyotroph. Lateral Scler., 8: 189-190, 2008. (Pubitemid 46887919)
7. Arai T., Hasegawa M., Akiyama H., Ikeda K., Nonaka T., Mori H., Mann D., Tsuchiya K., Yoshida M., Hashizume Y., Oda T. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem. Biophis. Res. Commun., 351: 602-611, 2006. (Pubitemid 44708852)
8. Armstrong R.A., Lantos P.L., Cairns N.J. Overlap between neurodegenerative disorders. Neuropathology, 25: 111-124, 2005. (Pubitemid 40571389)
9. Avants B., Khan A., McCluskey L. Elman, L. and Grossman M. Longitudinal cortical atrophy in amyotrophic lateral sclerosis with frontotemporal dementia. Arch. Neurol., 66: 138-139, 2009.
10. Bak T.H. and Hodges J.R. Motor neurone disease, dementia and aphasia: coincidence, co-occurrence or continuum? J. Neurol., 248: 260-270, Review, 2001. (Pubitemid 32323863)
11. Bak T.H., O'Donovan D., Xuereb J.H., Boniface S., Hodges J.R. Selective impairment of verb processing associated with pathological changes in Brodmann areas 44 and 45 in the motor neurone disease-dementia-aphasia syndrome. Brain, 124: 103-120, 2001. (Pubitemid 32055993)
12. Bak T.H. and Hodges J.R. The effects of motor neurone disease on language: further evidence. Brain and Language, 89: 354-361, 2004. (Pubitemid 38450742)
13. Bak T.H. Motor neuron diasease and frontotemporal dementia: One, two, or three disease. Ann. Indian. Acad. Neurol., 13: 31-38, 2010.
14. Benajiba L., Le Ber I., Camuzat A., Lacoste M., Thomas-Anterion C., Couratier P., Legallic S., Salachas F., Hannequin D., Decousus M., Lacomblez L., Guedj E., Golfier V., Camu W., Dubois B., Campion D., Meininger V., Brice A. French Clinical and Genetic Research Network on Frontotemporal Lobar Degeneration/Frontotemporal Lobar Degeneration with Motoneuron Disease. TARDBP mutations in motoneuron disease with frontotemporal lobar degeneration. Ann. Neurol., 65: 470-473, 2009.
15. Boccardi M., Sabattoli F., Laasko M.P., Testa M., Rossi R., Beltramello A., Soininen H., Frisoni G.B. Frontotemporal dementia as a neural system disease. Neurobiol. Aging, 26: 37-44, 2005. (Pubitemid 39600589)
16. Boxer A.L., Mackenzie I.R., Boeve B.F., Baker M., Seeley W.W., Crook R., Feldman H., Hsiung G.Y., Rutherford N., Laluz V., Whitwell J., Foti D., McDade E., Molano J., Karydas A., Wojtas A., Goldman J., Mirsky J., Sengdy P., Dearmond S., Miller B.L., Rademakers R. Clinical, neuroimaging and neuropathological features of a new chromosome 9p-linked FTD-ALS family. J. Neurol. Neurosurg. Psychiatry, 82: 196-203, 2011.
17. Brooks B.R. El Escorial Wordl Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommitee on Motor Neuron Disease/Amyotrophic Lateral Sclerosis of the Wordl Federation of Neurology Research Group on Neuromuscular Disease and the El Escorial 'Clinical limits of amyotrophic lateral sclerosis' workshop contributors. J. Neurol. Sci., 124 (Suppl.): 96-107, 1994.
18. Brooks B.R., Miller R.G., Swash M. Munsat T.L. Wordl Federation of Neurology Research Group on Motor Neuron Diseases: El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph. Lateral Scler. Other Motor Neuron Disord., 1: 293-239, 2000.
19. Caselli R.J., Windebank A.J., Petersen R.C., Komori T., Parisi J.E., Okazaki H., Kokmen E., Iverson R., Dinapoli R.P., Graff-Radford N.R., et al. Rapidly progressive aphasic dementia and motor neuron disease. Ann. Neurol., 33: 200-207, 1993. (Pubitemid 23039929)
20. Catani M., Piccirilli M., Geloso M.C., Cherubini A. , Finali G., Pelliccioli G., Senin U., Mecocci, P. Rapidly Progressive Aphasic Dementia with motor neuron disease: a distinctive clinical entity. Dement. Geriat. Cogn. Disord., 17: 21-28, 2004. (Pubitemid 37499963)
21. Cavalleri F. and De Renzi E. Amyotrophic lateral sclerosis with dementia. Acta Neurol. Scand., 89: 391-394, 1994. (Pubitemid 24163656)
22. Chang J.L., Lomen-Hoerth C., Murphy J., Henry R.G., Kramer J.H., Miller B.L., Gorno-Tempini M.L. A voxel-based morphometry study of patterns of brain atrophy in ALS and ALS/FTLD. Neurology, 65: 75-80, 2005. (Pubitemid 40967780)
23. Corrado L., Ratti A., Gellera C., Buratti E., Castellotti B., Carlomagno Y., Ticozzi N., Mazzini L., Testa L., Taroni F., Baralle F.E., Silani V., D'Alfonso S. High frequency of TARDBP gene mutations in Italian patients with amyotrophic lateral sclerosis. Hum. Mutat., 30: 688-694, 2009.
24. Corsino G.M. and Lugaresi E. Sclerosi laterale amiotrofica e turbe psichiche. Riv. Sper. Freniatr. Med. Leg., 80: 870-876, 1956.
25. Cullerre A. Troubles mentales dans la sclérose latérale amyotrophique. Archives de Neurologie, 21: 433-450, 1906.
26. Cummings J.L., Mega M., Gray K., Rosenberg-Thompson S., Carusi D.A., Gornbein J. The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology, 44: 2308-2314, 1994. (Pubitemid 24382728)
27. Dalakas M.C., Hatazawa J., Brooks R.A., Di Chiro G..Lowered cerebral glucose utilization in amyotrophic lateral sclerosis. Ann. Neurol., 22: 580-586, 1987. (Pubitemid 17162899)
28. De Caro D. Un caso di sclerosi laterale amiotrofica con demenza. Contributo allo studio delle lesioni corticali nella malattia di Charcot. Rass. Studi Psichiatr., 30: 705-722, 1941.
29. Delay J., Brion S., Escourolle R., Marty R. Sclérose latérale amyotrophique et démence (a propos de deux cas anatomo-cliniques). Rev. Neurol., 100: 191-204, 1959.
30. Doran M., Xuereb J., Hodges J.R. Rapidly progressive aphasia with bulbar motor neuron disease: a clinical and neuropsychological study. Behav. Neurol., 8: 169-180, 1995. (Pubitemid 26011312)
31. Dubois B and Andrade K. Executive dysfunction and neuropsychological testing. In: Duyckarten C., Litvan I. (Eds.) Dementia (Handbook of Clinical Neurology Vol. 89) (3nd series). Elsevier B.V., 2008.
32. Elman L.B., McCluskey L. Grossman M. Motor neuron disease and frontotemporal lobar degeneration: a tale of two disorders linked to TDP-43. Neurosignals, 16: 85-90, 2008. (Pubitemid 350308324)
33. Ferguson J.H. and Boller F. A different form of agraphia: syntactic writing errors in patients with motor speech and movement disorders. Brain Lang., 4: 382-389, 1977. (Pubitemid 8114535)
34. Ferrer I., Roig C., Espino A., Peiro G., Matias Guiu X. Dementia of frontal lobe type and motor neuron disease. A Golgi study of the frontal cortex. J. Neurol. Neurosurg. Psychiatry, 54: 932-934, 1991.
35. Flaherty-Craig C., Eslinger P., Stephens B., et al. A rapid screening battery to identify frontal dysfunction in patients with ALS. Neurology, 67: 2070-2072, 2006. (Pubitemid 44967396)
36. Fragnito O. I disturbi psichici nella sclerosi laterale amiotrofica. Annali di Neurologia, 25: 273-287, 1907.
37. Gainotti G., Ferraccioli M., Quaranta D., Marra C. Cross-modal recognition disorders for persons and other unique entities in a patient with right frontotemporal degeneration. Cortex, 44: 238-248, 2008. (Pubitemid 351722603)
38. Garraux G, Salmon E., Degueldre C., Lemaire C., Franck G. Medial temporal lobe metabolic impairment in dementia associated with motor neuron disease. Neuroimage, 10: 149-162, 1999.
39. Gentile F. I disturbi psichici nella sclerosi laterale amiotrofica. Annali della Clinica delle Malattie Mentali e Nervose della R. Università di Palermo, 3: 330-349, 1909.
40. Geser F., Martinez-Lage M., Kwong L.K., Lee V.M., Trojanowski J.Q. Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases. J. Neurol., 256: 1205-1214, 2009.
41. Gibbons Z.C., Snowden J.S., Thompson J.C., Happè F., Richardson A. Neary D. Inferring thought and action in motor neurone disease. Neuropsychologia, 45: 1196-1207, 2007. (Pubitemid 46072913)
42. Gibbons Z.C., Richardson A., Neary D., Snowden J.S. Behaviour in amyotrophic lateral sclerosis. Amyotroph. Lateral Scler., 9: 67-74, 2008. (Pubitemid 351584031)
43. Gordon PH, Wang Y, Doorish C, Lewis M, Battista V, Mitsumoto H, Marder K. A screening assessment of cognitive impairment in patients with ALS. Amyotroph. Lateral. Scler., 8: 362-5, 2007. (Pubitemid 350176935)
44. Gorno-Tempini M.L., Dronkers N.F., Rankin K.P., Ogar J.M., Phengrasamy L., Rosen H.J., Johnson J.K., Weiner M.W., Miller B.L. Cognition and anatomy in three variants of primary progressive aphasia. Ann. Neurol., 55: 335-346, 2004. (Pubitemid 38269585)
45. Gorno-Tempini M.L., Hillis A.E., Weintraub S., Kertesz A., Mendez M., Cappa S.F., Ogar J.M., Rohrer J.D., Black S., Boeve B.F., Manes F., Dronkers N.F., Vandenberghe R., Rascovsky K., Patterson K., Miller B.L., Knopman D.S., Hodges J.R., Mesulam M.M., Grossman M. Classification of primary progressive aphasia and its variants. Neurology, 76: 1006-1014, 2011.
46. Gozzano M. Sulla istopatologia e la patogenesi della sclerosi laterale amiotrofica. Riv. Neurol., 5: 165-216, 1936.
47. Grossman M. Primary progressive aphasia: clinicopathological correlations. Nat. Rev. Neurol., 6: 88-97, 2010.
48. Guedj E., Le Ber I., Lacomblez L., Dubois B., Verpillat P., Didic M., Salachas F., Vera P., Hannequin D., Lotterie J.A., Puel M., Decousus M., Thomas-Antérion C., Magne C., Vercelletto M., Bernard A.M., Golfier V., Pasquier J., Michel B.F., Namer I., Sellal F., Bochet J., Volteau M., Brice A., Meininger V., French Research Network on FTD/FTD-MND, Habert M.O. Brain spect perfusion of frontotemporal dementia associated with motor neuron disease. Neurology, 69: 488-490, 2007. (Pubitemid 47450285)
49. Hodges J.R. and Miller B. The neuropsychology of frontal variant frontotemporal dementia and semantic dementia. Introduction to the special topic papers: Part II. Neurocase, 7: 113-121, 2001. (Pubitemid 32457856)
50. Hodges J.R., Davies R.R., Xuereb J.H., Casey B., Broe M., Bak T.H., Kril J.J., Halliday G.M. Clinicopathological correlates in frontotemporal dementia. Ann. Neurol., 56: 399-406, 2004. (Pubitemid 39166559)
51. Ichikawa H., Koyama S., Ohno H., Ishihara K., Nagumo K., Kawamura M. Writing errors and anosognosia in amyotrophic lateral sclerosis with dementia. Behav. Neurol., 19: 107-116, 2008. (Pubitemid 352039944)
52. Iivanainen M., Laaksonen R., Niemi M.L., Färkkilä M., Bergström L., Mattson K., Niiranen A., Cantell K. Memory and psychomotor impairment following high-dose interferon treatment in amyotrophic lateral sclerosis. Acta Neurol. Scand., 72: 475-480, 1985. (Pubitemid 16204983)
53. Irwin D., Lippa C.F., Swearer J.M. Cognition and amyotrophic lateral sclerosis (ALS). Am. J. Alzheimers Dis. OtherDemen., 22: 300-312, 2007. (Pubitemid 47330150)
54. Iversen I.H., Ghanayim N., Kübler A., Neumann N., Birbaumer N., Kaiser J. A brain-computer interface tool to assess cognitive functions in completely paralyzed patients with amyotrophic lateral sclerosis, Clin. Neurophysiol., 119: 2214-2223, 2008.
55. Jackson M., Lennox G., Lowe J. Motor neurone disease-inclusion dementia. Neurodegeneration, 5: 339-350, 1996. (Pubitemid 27077893)
56. Josephs K.A., Knopman D.S., Whitwell J.L., Boeve B.F., Parisi J.E., Petersen R.C., Dickson D.W. Survival in two variants of tau-negative frontotemporal lobar degeneration: FTLD-U vs FTLD-MND. Neurology, 65: 645-647, 2005. (Pubitemid 41170737)
57. Kabashi E., Valdmanis P.N., Dion P., Spiegelman D., McConkey B.J., Vande Velde C., Bouchard J.P., Lacomblez L., Pochigaeva K., Salachas F., Pradat P.F., Camu W., Meininger V., Dupre N., Rouleau G.A. TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat. Genet., 40: 572-574, 2008. (Pubitemid 351601218)
58. Kato S., Oda M., Hayashi H., Kawata A., Shimizu T. Participation of the limbic system and its associated areas in the dementia of amyotrophic lateral sclerosis. J. Neurol. Sci., 126: 62-69, 1994. (Pubitemid 24305260)
59. Kertesz A., Nadkarni N., Davidson W., Thomas A.W. The Frontal Behavioral Inventory in the differential diagnosis of frontotemporal dementia. J. Int. Neuropsychol. Soc., 6: 460-468, 2000. (Pubitemid 30394399)
60. Kew J.J.M., Goldstein L.H., Leigh P.N., Abrahams S., Cograve N., Passingham R.E., Frackowiak R.S.J., Brooks D.J. The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis: A neurocognitive and positron emission tomography study. Brain, 116: 1399-1423, 1993. (Pubitemid 24038859)
61. Kiernan J.A. and Hudson A.J. Frontal lobe atrophy in motor neuron diseases. Brain, 117: 747-757, 1994. (Pubitemid 24281837)
62. Kilani M., Micallef J., Soubrouillard C., Rey-Lardiller D., Demattei C., Dib M., Philippot P., Ceccaldi M., Pouget J., Blin O. A longitudinal study of the evolution of cognitive function and affective state in patients with amyotrophic lateral sclerosis. Amyotroph. Lateral Scler. Other Motor Neuron Disord., 5: 46-54, 2004. (Pubitemid 38618735)
63. Kwiatkowski T.J. Jr, Bosco D.A., Leclerc A.L., Tamrazian E., Vanderburg C.R., Russ C., Davis A., Gilchrist J., Kasarskis E.J., Munsat T., Valdmanis P., Rouleau G.A., Hosler B.A., Cortelli P., de Jong P.J., Yoshinaga Y., Haines J.L., Pericak-Vance M.A., Yan J., Ticozzi N., Siddique T., McKenna-Yasek D., Sapp P.C., Horvitz H.R., Landers J.E., Brown R.H. Jr. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science, 323: 1205-1208, 2009.
64. Lagier-Tourenne C. and Cleveland D.W. Rethinking ALS: the FUS about TDP-43. Cell, 136: 1001-1004, 2009.
65. Lakerveld J, Kotchoubey B, Kübler A. Cognitive function in patients with late stage amyotrophic lateral sclerosis. J. Neurol. Neurosurg. Psychiatry, 79 (1): 25-29, 2008.
66. Lamer A.J. Delusion of pregnancy in frontotemporal lobar degeneration with motor neurone disease (FTDL/MND). Behav. Neurol., 19: 199-200, 2008.
67. Lillo P. and Hodges J.R. Frontotemporal dementia and motor neurone disease: Overlapping clinicpathological disorders. J. Clin. Neurosci., 16: 1131-1135, 2009.
68. Lloyd C.M., Richardson M.P., Brooks D.J., Al-Chalabi A., Leigh P.N. Extramotor involvement in ALS: PET studies with the GABA(A) ligand [(11)C] flumazenil. Brain, 123: 2289-2296, 2000.
69. Lomen-Hoerth C., Anderson T., Miller B. The overlap of amyotrophic lateral sclerosis and frontotemporal dementia. Neurology, 59: 1077-1079, 2002.
70. Lomen-Hoerth C., Murphy J., Langmore S., Kramer J.H., Olney R.K., Miller B. Are amyotrophic lateral sclerosis patients cognitively normal? Neurology, 60: 1094-1097, 2003. (Pubitemid 36418766)
71. Ludolph A.C., Langer K.J., Regard M. Herzog H., Kemper B., Kuwert T., Böttger I.G., Feinendegen L. Frontal lobe function in amyotrophic lateral sclerosis: a neuropsychologic and positron emission tomography study. Acta Neurol. Scand., 85: 81-89, 1992.
72. Mackenzie I.R., Baborie A., Pickering-Brown S., Du Plessis D., Jaros E., Perry R.H., Neary D., Snowden J.S., Mann D.M. Heterogeneity of ubiquitin pathology in frontotemporal lobar degeneration: classification and relation to clinical phenotype. Acta Neuropathol., 112: 539-549, 2006. (Pubitemid 44550678)
73. Mackenzie I.R. and Rademakers R. The role of TDP-43 in amyotrophic lateral sclerosis and frontotemporal dementia. Curr. Opin. Neurol., 21: 693-700, 2008.
74. Mackenzie I.R., Neumann M., Bigio E.H., Cairns N.J., Alafuzoff I., Kril J., Kovacs G.G., Ghetti B., Halliday G., Holm I.E., Ince P.G., Kamphorst W., Revesz T., Rozemuller A.J., Kumar-Singh S., Akiyama H., Baborie A., Spina S., Dickson D.W., Trojanowski J.Q., Mann D.M. Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathol., 117: 15-18, 2009.
75. Mackenzie I.R., Neumann M., Bigio E.H., Cairns N.J., Alafuzoff I., Kril J., Kovacs G.G., Ghetti B., Halliday G., Holm I.E., Ince P.G., Kamphorst W., Revesz T., Rozemuller A.J., Kumar-Singh S., Akiyama H., Baborie A., Spina S., Dickson D.W., Trojanowski J.Q., Mann D.M. Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathol., 119: 1-4, 2010.
76. Marie P. Legons sur le maladies de la moelle. Paris, Masson & Cie, 1892.
77. Massman P.J., Sims J., Cooke N., Haverkamp L.J., Appel V., Appel S.H. Prevalence and correlates of neuropsychological deficits in amyotrophic lateral sclerosis. J. Neurol. Neurosurg. Psychiatry, 61: 450-455, 1996. (Pubitemid 26394900)
78. McKhann G.M., Albert M.S., Grossman M., Miller B., Dickson D., Trojanowski J.Q.; Work Group on Frontotemporal Dementia and Pick's Disease. Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease. Arch. Neurol., 58: 1803-1809, 2001. (Pubitemid 33044246)
79. Mesulam M., Rogalski E., Wieneke C., Cobia D., Rademaker A., Thompson C., Weintraub S. Neurology of anomia in the semantic variant of primary progressive aphasia. Brain., 132: 2553-2565, 2009.
80. Mezzapesa D.M., Ceccarelli A., Dicuonzo F., Carella A., De Caro M.F., Lopez M., Samarelli V., Livrea P., Simone I.L. Whole-Brain and regional brain atrophy in amyotrophic lateral sclerosis. Am. J. Neuroradiol., 28: 255-259, 2007. (Pubitemid 46281040)
81. Michaux L., Samson M., Harl J-M., Gruener J. Èvolution démentielle de deux cas de sclérose latérale amyotrophique accompagnée d'aphasie. Rev. Neurol., 92: 357-367, 1955.
82. Moretti R., Torre P., Antonello R.M., Carraro N., Cazzato G., Bava A. Complex cognitive disruption in motor neuron disease. Dement. Geriatr. Cogn. Disord., 14: 141-150, 2002.
83. Murphy J.M., Roland G.H., Langmore S., Kramer J.H., Miller B.L., Lomen-Hoerth C. Continuum of frontal lobe impairment in amyotrophic lateral sclerosis. Arch. Neurol., 64: 530-534, 2007. (Pubitemid 46588341)
84. Neary D., Snowden J.S., Gustafson L., Passant U., Stuss D., Black S., Freedman M., Kertesz A., Robert P.H., Albert M., Boone K., Miller B.L., Cummings J., Benson D.F. Frontotemporal lobar degeneration. A consensus on clinical diagnostic criteria. Neurology, 51: 1546-1554, 1998.
85. Neary D., Snowden J.S., Mann D.M., Northen B., Goulding P.J., Macdermott N. Frontal lobe dementia and motor neuron disease. J. Neurol. Neurosurg. Psychiatry, 53: 23-32, 1990. (Pubitemid 20034359)
86. Neary D., Snowden J.S., Mann D.M. Cognitive change in motor neurone disease/amyotrophic lateral sclerosis (MND/ALS). Neurol. Sci., 180: 15-20, 2000.
87. Neary D., Snowden J., and Mann D. Frontotemporal dementia. Lancet Neurology, 4: 771-780, 2005. (Pubitemid 41457293)
88. Neumann M., Sampathu D.M., Kwong L.K., Truax A.C., Micsenyi M.C., Chou T.T., Bruce J., Schuck T., Grossman M., Clark C.M., McCluskey L.F., Miller B.L., Masliah E., Mackenzie I.R., Feldman H., Feiden W., Kretzschmar H.A., Trojanowski J.Q., Lee V.M. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science, 314: 130-133, 2006. (Pubitemid 44547757)
89. Neumann M., Kwong L.K., Lee E.B., Kremmer E., Flatley A., Xu Y., Forman M.S., Troost D., Kretzschmar H.A., Trojanowski J.Q., Lee V.M. Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathol., 117: 137-149, 2009.
90. Neumann N. and Kotchoubey B. Assessment of cognitive functions in severely paralysed and severely brain-damaged patients: neuropsychological and electrophysiological methods. Brain Res Brain Res Protoc., 14 (1): 25-36, 2004. (Pubitemid 39446433)
91. Nitrini R. and Rosemberg S. Psychotic symptoms in dementia associated with motor neuron disease: a pathophysiological hypothesis. J. Neuropsychiatry Clin. Neurosci., 10: 456-458, 1998. (Pubitemid 28505399)
92. Ohnishi T., Hoshi H., Jinnouchi S., Nagamachi S., Watanabe K., Mituyama Y. The utility of cerebral blood flow imaging in patients with the unique syndrome of progressive dementia with motor neuron disease. J. Nucl. Med., 31: 688-691, 1990. (Pubitemid 20179714)
93. Olney R.K., Murphy J., Forshew D., Garwood E., Miller B.L., Langmore S., Kohn M.A., Lomen-Hoerth C. The effects of executive and behavioural dysfunction on the course of ALS. Neurology, 65: 1774-1777, 2005.
94. Phukan J., Pender N., Hardiman O. Cognitive impairment in amyotrophic lateral sclerosis. Lancet Neurology, 6: 994-1003, 2007. (Pubitemid 47562321)
95. Pilcz A. Uber ein Fall von amyotrophische laterale Sklerose und Paranoia. Jahrbuch für Psychologie und Neurologie, 17: 221-222, 1898.
96. Poletti B., Maringelli F., Lafronza A., Lombardi C., Meriggi P., Silani V. Anti-saccade paradigm in the cognitive frontal assessment of Amyotrophic Lateral Sclerosis. Amyotroph. Lateral Scler. other Motor. Neuron Disord., 10 (Suppl 1): 45, 2009.
97. Portet F., Cadilhac C., Touchon J., Camu W. Cognitive impairment in motor neuron disease with bulbar onset. Amyotroph. Lateral Scler. Other Motor Neuron Disord., 2: 23-29, 2001. (Pubitemid 32472145)
98. Raaphorst J., de Visser M., Linssen W.H., de Haan R.J., Schmand B. The cognitive profile of amyotrophic lateral sclerosis: A meta-analysis. Amyotroph. Latreral Scler., 11: 27-37, 2010.
99. Rakowicz W.P. and Hodges J.R. Dementia and aphasia in motor neuron disease: an underrecognised association? Neurol. Neurosurg. Psychiatry, 65: 881-889, 1998. (Pubitemid 128710429)
100. Resegotti E. Un caso di sclerosi laterale amiotrofica osservato nella clinica neuropatologica di Pavia. Il Morgagni, 49: 301-316, 1907.
101. Ringholz G.M., Appel S.H., Bradshaw M., Cooke N.A., Mosnik D.M., Schulz P.E. Prevalence and patterns of cognitive impairment in sporadic ALS. Neurology, 65: 586-590, 2005. (Pubitemid 41170719)
102. Rippon G.A., Scarmeas N., Gordon P.H. Murphy P.L., Albert S.M., Mitsumoto H., Marder K., Rowland L.P., Stern Y. An observational study of cognitive impairment in amyotrophic lateral sclerosis. Arch. Neurol., 63: 345-352, 2006.
103. Robertson E. Progressive bulbar analysis heredofamiliar incidence and intellectual impairment. Arch. Neurol. Psychiatry, 69: 197-207, 1953.
104. Robinson K.M., Lacey S.C., Grugan P., Glosser G., Grossman M., McCluskey L.F. Cognitive functioning in sporadic amyotrophic lateral sclerosis: a six month longitudinal study. J. Neurol. Neurosurg. Psychiatry, 77: 668-670, 2006. (Pubitemid 43844596)
105. Safa Al-Sarraj. Dementia and motor neuron disease. In: Duyckarten C., Litvan I. (Eds.) Dementia (Handbook of Clinical Neurology Vol. 89) (3nd series). Elsevier B.V., 2008.
106. Sampathu D.M., Neumann M., Kwong L.K., Chou T.T., Micsenyi M., Truax A., Bruce J., Grossman M., Trojanowski J.Q., Lee V.M. Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies. Am. J. Pathol., 169: 1343-1352, 2006. (Pubitemid 351194368)
107. Schreiber H., Gaigalat T., Wiedemuth-Catrinescu U., Graf M., Uttner I., Muche R., Ludolph A.C. Cognitive function in bulbarand spinal-onset amyotrophic lateral sclerosis. A longitudinal study in 52 patients. J. Neurol., 252: 772-781, 2005. (Pubitemid 40984851)
108. Shatunov A., Mok K., Newhouse S., Weale M.E., Smith B., Vance C., Johnson L., Veldink J.H., Van Es M., Van Den Berg L., Robberecht W., van Damme P., Hardiman O., Farmer A.E., Lewis C.M., Butler W.-L., Abel O., Andersen P.M., Fogh I., Silani V., Chiò A., Traynor B.J., Melki J., Meininger V., Landers J.E., McGuffin P.D., Glass J.D., Pall H., Leigh P.N., Hardy J., Brown, R.H.Jr, Powell J.F., Orrell R., Morrison K.E., Shaw P.J., Shaw C.E., Al-Chalabi A. Chromosome 9p21.2 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. Lancet Neurol, 10: 986-994, 2010.
109. Silveri M.C. Frontotemporal dementia to Alzheimer's disease. Dialogues Clin. Neurosci., 9: 153-160, 2007. (Pubitemid 47075463)
110. Sreedharan J., Blair I.P., Tripathi V.B., Hu X., Vance C., Rogelj B., Ackerley S., Durnall J.C., Williams K.L., Buratti E., Baralle F., de Belleroche J., Mitchell J.D., Leigh P.N., Al-Chalabi A., Miller C.C., Nicholson G., Shaw C.E. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science, 319: 1668-1672, 2008. (Pubitemid 351432505)
111. Stout J.C., Ready R.E., Grace J., Malloy P.F., Paulsen J.S. Factor analysis of the frontal systems behavior scale (FrSBe). Assessment, 10: 79-85, 2003. (Pubitemid 44534450)
112. Strong M.J., Grace G.M., Orange J.B., Leeper H.A., Menon R.S., Aere C. A prospective study of cognitive impairment in ALS. Neurology, 53: 1665-1670, 1999. (Pubitemid 29530337)
113. Strong M.J., Lomen-Hoerth C., Caselli R.J., Bigio E.H., Yang W. Cognitive impairment, frontotemporal dementia, and the motor neuron diseases. Ann. Neurol., 54: S20-23, 2003. (Pubitemid 36760149)
114. Strong M.J., Grace G.M., Freedman M., Lomen-Hoerth C., Woolley S., Goldstein L.H., Murphy J., Shoesmith C., Rosenfeld J., Leigh P.N., Bruijn L., Ince P., Figlewicz D. Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis. Amyotroph. Lateral Scler., 10: 131-146, 2009.
115. Stukovnik V., Zidar J., Podnar S., Repovs G. Amyotrophic lateral sclerosis patients show executive impairments on standard neuropsychological measures and an ecologically valid motor-free test of executive functions. J. Clin. Exp. Neuropsychol., 24: 1-15, 2010.
116. Talbot P.R., Goulding P.J., Lloyd J.I., Snowden J.S., Neary D., Testa H.J. Inter-relation between "classic" motor neuron disease and frontotemporal dementia: neuropsychological and single photon emission computed tomography. J. Neurol. Neurosurg. Psychiatry, 58: 541-547, 1995.
117. The Lund and Manchester Groups. Clinical and neuropathological criteria for frontotemporal dementia. J. Neurol. Neurosurg. Psychiatry, 57: 416-418, 1994.
118. Ticozzi N., Silani V., LeClerc A.L., Keagle P., Gellera C., Ratti A., Taroni F., Kwiatkowski T.J.Jr, McKenna-Yasek D.M., Sapp P.C., Brown R.H.Jr, Landers J.E. Analysis of FUS gene mutation in familial amyotrophic lateral sclerosis within an Italian cohort. Neurology, 73: 1180-1185, 2009.
119. Ticozzi N., Tiloca C., Morelli C., Colombrita C., Poletti B., Doretti A., Maderna L., Messina S., Ratti A., Silani V. Genetics of Familial Amyotrophic Lateral Sclerosis. Arch. Ital. Biol., 149: 65-82, 2011 (this issue).
120. Tronconi V. Sindrome demenziale presenile e sclerosi laterale amiotrofica. Riv. Sper. Freniatr. Med. Leg., 65: 811-813, 1941.
121. Tsuji-Akimoto S., Hamada S., Yabe I., Tamura I., Otsuki M., Kobashi S., Sasaki H. Writing errors as a result of frontal dysfunction in Japanese patients with amyotrophic lateral sclerosis. J. Neurol., 257: 2071-2077, 2010.
122. Valdmanis P.N., Dupre N., Bouchard J.P., Camu W., Salachas F., Meininger V., Strong M., Rouleau G.A. Three families with amyotrophic lateral sclerosis and frontotemporal dementia with evidence of linkage to chromosome 9p. Arch. Neurol., 64: 240-245, 2007.
123. Vance C., Rogelj B., Hortobágyi T., De Vos K.J., Nishimura A.L., Sreedharan J., Hu X., Smith B., Ruddy D., Wright P., Ganesalingam J., Williams K.L., Tripathi V., Al-Saraj S., Al-Chalabi A., Leigh P.N., Blair I.P., Nicholson G., de Belleroche J., Gallo J.M., Miller C.C., Shaw C.E. Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science, 323: 1208-1211, 2009.
124. Van Deerlin V.M., Leverenz J.B., Bekris L.M., Bird T.D., Yuan W., Elman L.B., Clay D., Wood E.M., Chen-Plotkin A.S., Martinez-Lage M., Steinbart E., McCluskey L., Grossman M., Neumann M., Wu I.L., Yang W.S., Kalb R., Galasko D.R., Montine T.J., Trojanowski J.Q., Lee V.M., Schellenberg G.D., Yu C.E. TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis. Lancet Neurol., 7: 409-416, 2008.
125. Van Reeth P.C., Perier O., Coers C., Van B.L. Pick's dementia associated with atypical amyotrophic lateral sclerosis. (Anatomoclinical study). Acta Neurol. Belg., 61: 309-325, 1961.
126. 99m). Rev. Neurol., 151: 640-647, 1995. (Pubitemid 26024096)
127. Vercelletto M., Ronin M., Huvet M., Magne C., Feve J.R. Frontal type dementia preceding amyotrophic lateral sclerosis: a neuropsychological and SPECT study of five clinical cases. Eur. J. Neurol., 6: 295-299, 1999. (Pubitemid 29250988)
128. Von Braunmühl A. Picksche Krankheit und amyotrophische Lateralsklerose. Allgemeine Z. Psychiatr. Psychol. Med., 96: 364-366, 1932
129. Wechsler I.S. and Davison C. Amyotrophic lateral sclerosis with mental symptoms. Arch. Neurol. Psychiatry, 27: 859-880, 1932.
130. Whitwell J.L., Jack C.R.Jr, Senjem M.L., Josephs K.A. Patterns of atrophy in pathologically confirmed FTLD with and without motor neuron degeneration. Neurology, 66: 102-104, 2006. (Pubitemid 43739601)
131. Williams G.B., Nestor P.J., Hodges J.R. Neural correlates of semantic and behavioural deficits in frontotemporal dementia. Neuroimage, 24: 1042-1051,2005. (Pubitemid 40164506)
132. Wolley S.C. and Katz J.S. Cognitive and Behavioral Impairment in Amyotrophic Lateral Sclerosis. Phys. Med. Rehabil. Clin. N. Am., 19: 607-617, 2008.
133. Zago S., Poletti B., Corbo M., Adobbati L., Silani V. Dysgraphia in patients with primary lateral sclerosis: a speech-based rehearsal deficit? Behav. Neurol., 19: 169-175, 2008.
134. Ziegler L.L. Psychotic and emotional phenomena associated with amyotrophic lateral sclerosis. Arch. Neurol. Psychiatry, 24: 930-937, 1930.