Differential effects of HNF-1α mutations associated with familial young-onset diabetes on target gene regulation

Molecular Medicine

Volumn 17, Issue 3-4, 2011, Pages 256-265

  Galán, Maria ^a,b,c   García Herrero, Carmen Maria ^a,b   Azriel, Sharona ^d   Gargallo, Manuel ^e   Durán, Maria ^f   Gorgojo, Juan Jose ^g   Andía, Victor Manuel ^h   Navas, Maria Angeles ^a,b  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c AUTONOMOUS UNIVERSITY OF MADRID   (Spain)

^d HOSPITAL UNIVERSITARIO INFANTA SOFÍA   (Spain)

^e HOSPITAL UNIVERSITARIO INFANTA LEONOR   (Spain)

^f HOSPITAL UNIVERSITARIO DE GETAFE   (Spain)

^g HOSPITAL UNIVERSITARIO FUNDACIÓN ALCORCÓN   (Spain)

^h HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ARGININE; GLUTAMINE; GLUTATHIONE TRANSFERASE HEPATOCYTE NUCLEAR FACTOR 1ALPHA FUSION PROTEIN; GLYCINE; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HYBRID PROTEIN; METHIONINE; PROLINE; THREONINE; TRYPTOPHAN; UNCLASSIFIED DRUG; VALINE;

5' UNTRANSLATED REGION; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA BINDING; FAMILIAL DISEASE; GEL MOBILITY SHIFT ASSAY; GENE; GENE CONTROL; GENE FUNCTION; GENE TARGETING; GENETIC ASSOCIATION; GENETIC REGULATION; GENETIC VARIABILITY; HNF 1ALPHA GENE; HUMAN; HUMAN TISSUE; MATURITY ONSET DIABETES MELLITUS; MATURITY ONSET DIABETES MELLITUS OF THE YOUNG TYPE 3; MISSENSE MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; QUANTITATIVE STUDY; REPORTER GENE; TRANSCRIPTION INITIATION;

ADOLESCENT; ADULT; AGE OF ONSET; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; DIABETES MELLITUS; DNA MUTATIONAL ANALYSIS; FAMILY HEALTH; FEMALE; GENE EXPRESSION REGULATION; GENETIC TESTING; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HUMANS; LUCIFERASES; MALE; MUTATION; MUTATION, MISSENSE; PROMOTER REGIONS, GENETIC; SPAIN; YOUNG ADULT;

EID: 79952837279     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2010.00097     Document Type: Article

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