A hearing loss-associated myo1c mutation (R156W) decreases the myosin duty ratio and force sensitivity

Biochemistry

Volumn 50, Issue 11, 2011, Pages 1831-1838

  Lin, Tianming ^a   Greenberg, Michael J ^a   Moore, Jeffrey R ^a   Ostap, E Michael ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP BINDING; DUTY RATIOS; FORCE SENSITIVITY; HAIR CELLS; HEARING LOSS; IN-VITRO; MOTOR DOMAIN; PHOSPHATE RELEASE; POINT MUTATIONS; RESISTING FORCES; SENSORINEURAL HEARING LOSS; SURFACE DENSITY; WILD TYPES; WILD-TYPE PROTEINS;

AUDITION;

PROTEINS;

ACTIN; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; MYOSIN; MYOSIN 1C; MYOSIN ADENOSINE TRIPHOSPHATASE; PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; DISSOCIATION; FORCE; GENE CONSTRUCT; GENE MUTATION; GENETIC ASSOCIATION; HEARING LOSS; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; STEADY STATE; WILD TYPE;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANIMALS; HEARING LOSS; HYDROLYSIS; KINETICS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; MYOSINS;

EID: 79952802312     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1016777     Document Type: Article

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