Regenerative medicine for skin diseases: IPS cells to the rescue

Journal of Investigative Dermatology

Volumn 131, Issue 4, 2011, Pages 812-814

  Uitto, Jouni ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG;

CELL DIFFERENTIATION; CELL LINEAGE; CELL REGENERATION; EPIDERMOLYSIS BULLOSA; GRAFT REJECTION; HEART MUSCLE CELL; HEMATOPOIETIC CELL; HUMAN; KERATINOCYTE; MOSAICISM; NERVE CELL; OSTEOBLAST; PERIPHERAL BLOOD STEM CELL; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REGENERATIVE MEDICINE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SOMATIC CELL; TISSUE INJURY;

EID: 79952758979     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.2     Document Type: Note

References (18)

1. Aasen T, Belmonte JC (2010) Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cells. Nat Protoc 5:371-82
2. Aasen T, Raya A, Barrero MJ et al. (2008) Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat Biotechnol 11:1276-84
3. Aberdam D (2004) Derivation of keratinocyte progenitor cells and skin formation from embryonic stem cells. Int J Dev Biol 48:203-6 (Pubitemid 38807935)
4. Almaani N, Nagy N, Liu L et al. (2010) Revertant mosaicism in recessive dystrophic epidermolysis bullosa. J Invest Dermatol 130:1937-40
5. Bilousova G, Chen J, Roop DR (2011) Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage. J Invest Dermatol 131:857-64
6. Csete M (2010) Translational prospects for human induced pluripotent stem cells. Regen Med 5:509-19
7. Green H, Easley K, Iuchi S (2003) Marker succession during the development of keratinocytes from cultured human embryonic stem cells. Proc Natl Acad Sci USA 100:15625-30 (Pubitemid 38021040)
8. Grinnell KL, Bickenbach JR (2007) Skin keratinocytes pre-treated with embryonic stem cell-conditioned medium or BMP4 can be directed to an alternative cell lineage. Cell Prolif 40:685-705 (Pubitemid 47416554)
9. Itoh M, Christiano A (2010) Differentiation of human induced pluripotent stem (iPS) cells into keratinocytes. J Invest Dermatol 130:s83 (abstract)
10. Lai-Cheong JE, McGrath JA, Uitto J (2011) Revertant mosaicism in skin: natural gene therapy. Trends Mol Med (in press)
11. Okita K, Nakagawa M, Hyenjong H et al. (2008) Generation of mouse induced pluripotent stem cells without viral vectors. Science 322:949-53
12. Pasmooij AM, Garcia M, Escamez MJ et al. (2010) Revertant mosaicism due to a second-site mutation in COL7A1 in a patient with recessive dystrophic epidermolysis bullosa. J Invest Dermatol 130:2407-11
13. Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663-76 (Pubitemid 44233629)
14. Tolar J, Xia L, Riddle MJ et al. (2011) Induced pluripotent stem cells from individuals with recessive dystrophic epidermolysis bullosa. J Invest Dermatol 131:848-56
15. Uitto J, McGrath JA, Rodeck U et al. (2010) Progress in epidermolysis bullosa research: toward treatment and cure. J Invest Dermatol 130:1778-84
16. Urnov FD, Rebar EJ, Holmes MC et al. (2010) Genome editing with engineered zinc finger nucleases. Nat Rev Genet 11:636-46
17. Vogel G (2010) Stem cells: diseases in a dish take off. Science 330:1172-3
18. Warren L, Manos PD, Ahfeldt T et al. (2010) Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7:618-30