메뉴 건너뛰기




Volumn 406, Issue 3, 2011, Pages 389-395

PPARγ ligands induce growth inhibition and apoptosis through p63 and p73 in human ovarian cancer cells

Author keywords

Cell death; Ovarian cancer cells; P63; P73; PPAR ligands

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; CASPASE 3; CIGLITAZONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; PROTEIN BAX; PROTEIN P21; PROTEIN P63; PROTEIN P73; SHORT HAIRPIN RNA; TROGLITAZONE;

EID: 79952739732     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.052     Document Type: Article
Times cited : (38)

References (30)
  • 2
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • Kersten S., Desvergne B., Wahli W. Roles of PPARs in health and disease. Nature 2000, 405:421-424.
    • (2000) Nature , vol.405 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 3
    • 53149098608 scopus 로고    scopus 로고
    • Potential of peroxisome proliferator-activated receptor gamma antagonist compounds as therapeutic agents for a wide range of cancer types
    • Burton J.D., Goldenberg D.M., Blumenthal R.D. Potential of peroxisome proliferator-activated receptor gamma antagonist compounds as therapeutic agents for a wide range of cancer types. PPAR Res. 2008, 2008:494161.
    • (2008) PPAR Res. , vol.2008 , pp. 494161
    • Burton, J.D.1    Goldenberg, D.M.2    Blumenthal, R.D.3
  • 4
    • 3042815666 scopus 로고    scopus 로고
    • Antineoplastic effects of peroxisome proliferatoractivated receptor [gamma] agonists
    • Grommes C., Landreth G.E., Heneka M.T. Antineoplastic effects of peroxisome proliferatoractivated receptor [gamma] agonists. Lancet Oncol. 2004, 5:419-429.
    • (2004) Lancet Oncol. , vol.5 , pp. 419-429
    • Grommes, C.1    Landreth, G.E.2    Heneka, M.T.3
  • 5
    • 58549099485 scopus 로고    scopus 로고
    • Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARgamma-dependent and PPARgamma-independent pathways
    • Lyles B.E., Akinyeke T.O., Moss P.E., Stewart L.V. Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARgamma-dependent and PPARgamma-independent pathways. Cell Cycle 2009, 8:268-277.
    • (2009) Cell Cycle , vol.8 , pp. 268-277
    • Lyles, B.E.1    Akinyeke, T.O.2    Moss, P.E.3    Stewart, L.V.4
  • 6
    • 74549184686 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor gamma ligands, pioglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2), have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells
    • Shim J., Kim B.H., Kim Y.I., Kim K.Y., Hwangbo Y., Jang J.Y., Dong S.H., Kim H.J., Chang Y.W., Chang R. The peroxisome proliferator-activated receptor gamma ligands, pioglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2), have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells. Int. J. Oncol. 2010, 36:223-231.
    • (2010) Int. J. Oncol. , vol.36 , pp. 223-231
    • Shim, J.1    Kim, B.H.2    Kim, Y.I.3    Kim, K.Y.4    Hwangbo, Y.5    Jang, J.Y.6    Dong, S.H.7    Kim, H.J.8    Chang, Y.W.9    Chang, R.10
  • 7
    • 59249086761 scopus 로고    scopus 로고
    • Suppression of pancreatic carcinoma growth by activating peroxisome proliferator-activated receptor gamma involves angiogenesis inhibition
    • Dong Y.W., Wang X.P., Wu K. Suppression of pancreatic carcinoma growth by activating peroxisome proliferator-activated receptor gamma involves angiogenesis inhibition. World J. Gastroenterol. 2009, 15:441-448.
    • (2009) World J. Gastroenterol. , vol.15 , pp. 441-448
    • Dong, Y.W.1    Wang, X.P.2    Wu, K.3
  • 8
    • 13944280963 scopus 로고    scopus 로고
    • Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARgamma
    • Shiau C.W., Yang C.C., Kulp S.K., Chen K.F., Chen C.S., Huang J.W., Chen C.S. Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARgamma. Cancer Res. 2005, 65:1561-1569.
    • (2005) Cancer Res. , vol.65 , pp. 1561-1569
    • Shiau, C.W.1    Yang, C.C.2    Kulp, S.K.3    Chen, K.F.4    Chen, C.S.5    Huang, J.W.6    Chen, C.S.7
  • 9
    • 33644978143 scopus 로고    scopus 로고
    • Rosiglitazone suppresses human lung carcinoma cell growth through PPARgamma-dependent and PPARgamma-independent signal pathways
    • Han S., Roman J. Rosiglitazone suppresses human lung carcinoma cell growth through PPARgamma-dependent and PPARgamma-independent signal pathways. Mol. Cancer Ther. 2006, 5:430-437.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 430-437
    • Han, S.1    Roman, J.2
  • 10
    • 70350511393 scopus 로고    scopus 로고
    • Friend or foe? Role of peroxisome proliferator-activated receptor-gamma in human bladder cancer
    • Inamoto T., Shah J.B., Kamat A.M. Friend or foe? Role of peroxisome proliferator-activated receptor-gamma in human bladder cancer. Urol. Oncol. 2009, 27:585-591.
    • (2009) Urol. Oncol. , vol.27 , pp. 585-591
    • Inamoto, T.1    Shah, J.B.2    Kamat, A.M.3
  • 12
    • 34547753615 scopus 로고    scopus 로고
    • and p73 in human cancer: defining the network, Oncogene
    • M.P. Deyoung, L.W. Ellisen, p63 and p73 in human cancer: defining the network, Oncogene (2007).
    • (2007) , pp. 63
    • Deyoung, M.P.1    Ellisen, L.W.2
  • 13
    • 0037513312 scopus 로고    scopus 로고
    • PPAR gamma ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells
    • Nagamine M., Okumura T., Tanno S., Sawamukai M., Motomura W., Takahashi N., Kohgo Y. PPAR gamma ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells. Cancer Sci. 2003, 94:338-343.
    • (2003) Cancer Sci. , vol.94 , pp. 338-343
    • Nagamine, M.1    Okumura, T.2    Tanno, S.3    Sawamukai, M.4    Motomura, W.5    Takahashi, N.6    Kohgo, Y.7
  • 14
    • 0035990751 scopus 로고    scopus 로고
    • Novel therapeutic approach: ligands for PPARgamma and retinoid receptors induce apoptosis in bcl-2-positive human breast cancer cells
    • Elstner E., Williamson E.A., Zang C., Fritz J., Heber D., Fenner M., Possinger K., Koeffler H.P. Novel therapeutic approach: ligands for PPARgamma and retinoid receptors induce apoptosis in bcl-2-positive human breast cancer cells. Breast Cancer Res. Treat. 2002, 74:155-165.
    • (2002) Breast Cancer Res. Treat. , vol.74 , pp. 155-165
    • Elstner, E.1    Williamson, E.A.2    Zang, C.3    Fritz, J.4    Heber, D.5    Fenner, M.6    Possinger, K.7    Koeffler, H.P.8
  • 17
    • 0032161624 scopus 로고    scopus 로고
    • P63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang A., Kaghad M., Wang Y., Gillett E., Fleming M.D., Dotsch V., Andrews N.C., Caput D., McKeon F. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol. Cell 1998, 2:305-316.
    • (1998) Mol. Cell , vol.2 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5    Dotsch, V.6    Andrews, N.C.7    Caput, D.8    McKeon, F.9
  • 18
    • 33846980459 scopus 로고    scopus 로고
    • Enhanced specificity of the p53 family proteins-based adenoviral gene therapy in uterine cervical cancer cells with E2F1-responsive promoters
    • Lee J.J., Kim S., Yeom Y.I., Heo D.S. Enhanced specificity of the p53 family proteins-based adenoviral gene therapy in uterine cervical cancer cells with E2F1-responsive promoters. Cancer Biol. Ther. 2006, 5:1502-1510.
    • (2006) Cancer Biol. Ther. , vol.5 , pp. 1502-1510
    • Lee, J.J.1    Kim, S.2    Yeom, Y.I.3    Heo, D.S.4
  • 19
    • 1642381346 scopus 로고    scopus 로고
    • Up-regulation of p21 gene expression by peroxisome proliferator-activated receptor gamma in human lung carcinoma cells
    • Han S., Sidell N., Fisher P.B., Roman J. Up-regulation of p21 gene expression by peroxisome proliferator-activated receptor gamma in human lung carcinoma cells. Clin. Cancer Res. 2004, 10:1911-1919.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 1911-1919
    • Han, S.1    Sidell, N.2    Fisher, P.B.3    Roman, J.4
  • 20
    • 33749573190 scopus 로고    scopus 로고
    • 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit ovarian cancer cell growth through peroxisome proliferator-activated receptor-dependent and independent pathways
    • Lei P., Abdelrahim M., Safe S. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit ovarian cancer cell growth through peroxisome proliferator-activated receptor-dependent and independent pathways. Mol. Cancer Ther. 2006, 5:2324-2336.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 2324-2336
    • Lei, P.1    Abdelrahim, M.2    Safe, S.3
  • 21
    • 0038121972 scopus 로고    scopus 로고
    • PPARgamma ligands inhibit cholangiocarcinoma cell growth through p53-dependent GADD45 and p21 pathway
    • Han C., Demetris A.J., Michalopoulos G.K., Zhan Q., Shelhamer J.H., Wu T. PPARgamma ligands inhibit cholangiocarcinoma cell growth through p53-dependent GADD45 and p21 pathway. Hepatology 2003, 38:167-177.
    • (2003) Hepatology , vol.38 , pp. 167-177
    • Han, C.1    Demetris, A.J.2    Michalopoulos, G.K.3    Zhan, Q.4    Shelhamer, J.H.5    Wu, T.6
  • 24
    • 0030816203 scopus 로고    scopus 로고
    • P53 mediated apoptosis in HeLa cells: transcription dependent and independent mechanisms
    • Haupt Y., Rowan S., Shaulian E., Kazaz A., Vousden K., Oren M. p53 mediated apoptosis in HeLa cells: transcription dependent and independent mechanisms. Leukemia 1997, 11(Suppl. 3):337-339.
    • (1997) Leukemia , vol.11 , Issue.SUPPL. 3 , pp. 337-339
    • Haupt, Y.1    Rowan, S.2    Shaulian, E.3    Kazaz, A.4    Vousden, K.5    Oren, M.6
  • 25
    • 0034079520 scopus 로고    scopus 로고
    • The p53/p63/p73 family of transcription factors: overlapping and distinct functions
    • Levrero M., De Laurenzi V., Costanzo A., Gong J., Wang J.Y., Melino G. The p53/p63/p73 family of transcription factors: overlapping and distinct functions. J. Cell Sci. 2000, 113(Pt 10):1661-1670.
    • (2000) J. Cell Sci. , vol.113 , Issue.PART 10 , pp. 1661-1670
    • Levrero, M.1    De Laurenzi, V.2    Costanzo, A.3    Gong, J.4    Wang, J.Y.5    Melino, G.6
  • 26
    • 77952238224 scopus 로고    scopus 로고
    • P53-family proteins and their regulators: hubs and spokes in tumor suppression
    • Collavin L., Lunardi A., Del Sal G. p53-family proteins and their regulators: hubs and spokes in tumor suppression. Cell Death Differ. 2010, 17:901-911.
    • (2010) Cell Death Differ. , vol.17 , pp. 901-911
    • Collavin, L.1    Lunardi, A.2    Del Sal, G.3
  • 29
    • 0037767838 scopus 로고    scopus 로고
    • When p53 needs p73 to be functional - forced p73 expression induces nuclear accumulation of endogenous p53 protein
    • Goldschneider D., Blanc E., Raguenez G., Haddada H., Benard J., Douc-Rasy S. When p53 needs p73 to be functional - forced p73 expression induces nuclear accumulation of endogenous p53 protein. Cancer Lett. 2003, 197:99-103.
    • (2003) Cancer Lett. , vol.197 , pp. 99-103
    • Goldschneider, D.1    Blanc, E.2    Raguenez, G.3    Haddada, H.4    Benard, J.5    Douc-Rasy, S.6
  • 30
    • 42549142975 scopus 로고    scopus 로고
    • P73 expression modulates p63 and Mdm2 protein presence in complex with p53 family-specific DNA target sequence in squamous cell carcinogenesis
    • Johnson J., Lagowski J., Lawson S., Liu Y., Kulesz-Martin M. p73 expression modulates p63 and Mdm2 protein presence in complex with p53 family-specific DNA target sequence in squamous cell carcinogenesis. Oncogene 2008, 27:2780-2787.
    • (2008) Oncogene , vol.27 , pp. 2780-2787
    • Johnson, J.1    Lagowski, J.2    Lawson, S.3    Liu, Y.4    Kulesz-Martin, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.