-
1
-
-
0033230181
-
HIF-1-mediated activation of transferring receptor gene transcription by iron chelation
-
Bianchi L, Tacchini L, Cairo G. 1999. HIF-1-mediated activation of transferring receptor gene transcription by iron chelation. Nucleic Acids Res 27: 4223-4227.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 4223-4227
-
-
Bianchi, L.1
Tacchini, L.2
Cairo, G.3
-
2
-
-
0029842459
-
Oxygen sensing and molecular adaptation to hypoxia
-
Bunn HF, Poyton RO. 1996. Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev 76: 839-885.
-
(1996)
Physiol Rev
, vol.76
, pp. 839-885
-
-
Bunn, H.F.1
Poyton, R.O.2
-
4
-
-
0030763856
-
Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene
-
Fleming MD, Trenor CC III, Su MA, Foernzler D, Beier DR, Dietrich WF, Andrews NC. 1997. Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nature Genet 16: 383-386.
-
(1997)
Nature Genet
, vol.16
, pp. 383-386
-
-
Fleming, M.D.1
Trenor III, C.C.2
Su, M.A.3
Foernzler, D.4
Beier, D.R.5
Dietrich, W.F.6
Andrews, N.C.7
-
5
-
-
0032477866
-
Nramp2 is mutated in the anemic Belgrade (b) rat:evidence of a role for Nramp2 in endosomal iron transport
-
Fleming MD, Romano MA, Su MA, Garrick LM, Garrick MD, Andrews NC. 1998. Nramp2 is mutated in the anemic Belgrade (b) rat:evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci USA 95: 1148-1153.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1148-1153
-
-
Fleming, M.D.1
Romano, M.A.2
Su, M.A.3
Garrick, L.M.4
Garrick, M.D.5
Andrews, N.C.6
-
6
-
-
0030755366
-
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
-
Gunshin H, Mackenzie B, Berger UV, Gunshin Y, Romero MF, Boron WF, Nussberger S, Gollan JL, Hediger MA. 1997. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 388: 482-488.
-
(1997)
Nature
, vol.388
, pp. 482-488
-
-
Gunshin, H.1
Mackenzie, B.2
Berger, U.V.3
Gunshin, Y.4
Romero, M.F.5
Boron, W.F.6
Nussberger, S.7
Gollan, J.L.8
Hediger, M.A.9
-
7
-
-
0032571304
-
Regulation of iron regulatory protein 1 during hypoxia and hypoxia/reoxygenation
-
Hanson ES, Leibold EA. 1998. Regulation of iron regulatory protein 1 during hypoxia and hypoxia/reoxygenation. J Biol Chem 273: 7588-7593.
-
(1998)
J Biol Chem
, vol.273
, pp. 7588-7593
-
-
Hanson, E.S.1
Leibold, E.A.2
-
8
-
-
0033582451
-
Hypoxia post-translationally activates iron-regulatory protein 2
-
Hanson ES, Foot LM, Leibold EA. 1999. Hypoxia post-translationally activates iron-regulatory protein 2. J Biol Chem 274: 5047-5052.
-
(1999)
J Biol Chem
, vol.274
, pp. 5047-5052
-
-
Hanson, E.S.1
Foot, L.M.2
Leibold, E.A.3
-
9
-
-
0038419500
-
Genistein protects primary cortical neurons from iron-induced lipid peroxidation
-
Ho KP, Li L, Zhao L, Qian ZM. 2003. Genistein protects primary cortical neurons from iron-induced lipid peroxidation. Mol Cell Biochem 247: 219-222.
-
(2003)
Mol Cell Biochem
, vol.247
, pp. 219-222
-
-
Ho, K.P.1
Li, L.2
Zhao, L.3
Qian, Z.M.4
-
11
-
-
0037126002
-
Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function
-
Hubert N, Hentze MW. 2002. Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function. Proc Natl Acad Sci USA 99: 12345-12350.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12345-12350
-
-
Hubert, N.1
Hentze, M.W.2
-
12
-
-
0035347260
-
Induction of HIF-1α in response to hypoxia is simultaneous
-
Jewell UR, Kvicukova T, Scheid A, Wenger RH, Gassmann M. 2001. Induction of HIF-1α in response to hypoxia is simultaneous. FASEB J 15: 1312-1314.
-
(2001)
FASEB J
, vol.15
, pp. 1312-1314
-
-
Jewell, U.R.1
Kvicukova, T.2
Scheid, A.3
Wenger, R.H.4
Gassmann, M.5
-
13
-
-
33751169387
-
Hypoxia-inducible factor-1 (HIF-1)
-
Ke Q, Costa M. 2006. Hypoxia-inducible factor-1 (HIF-1). Mol Pharmacol 70: 1469-1480.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1469-1480
-
-
Ke, Q.1
Costa, M.2
-
14
-
-
34748899552
-
Brain iron metabolism: Neurobiology and neurochemistry
-
Ke Y, Qian ZM. 2007. Brain iron metabolism: Neurobiology and neurochemistry. Prog Neurobiol 83: 149-173.
-
(2007)
Prog Neurobiol
, vol.83
, pp. 149-173
-
-
Ke, Y.1
Qian, Z.M.2
-
15
-
-
33645123990
-
Oxygen sensing in the body
-
Lahiri S, Roy A, Baby SM, Hoshi T, Semenza GL, Prabhakar NR. 2006. Oxygen sensing in the body. Prog Biophys Mol Biol 91: 249-286.
-
(2006)
Prog Biophys Mol Biol
, vol.91
, pp. 249-286
-
-
Lahiri, S.1
Roy, A.2
Baby, S.M.3
Hoshi, T.4
Semenza, G.L.5
Prabhakar, N.R.6
-
16
-
-
0031041377
-
Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia
-
Lee PJ, Jiang BH, Chin BY, Iyer NV, Alam J, Semenza GL, Choi AM. 1997. Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J Biol Chem 272: 5375-5381.
-
(1997)
J Biol Chem
, vol.272
, pp. 5375-5381
-
-
Lee, P.J.1
Jiang, B.H.2
Chin, B.Y.3
Iyer, N.V.4
Alam, J.5
Semenza, G.L.6
Choi, A.M.7
-
17
-
-
0032104739
-
The Human Nramp2 Gene: Characterizaton of the gene structure, alternative splicing, promoter region and polymorphisms
-
Lee PL, Gelbart T, West C, Halloran C, Beutler E. 1998. The Human Nramp2 Gene: Characterizaton of the gene structure, alternative splicing, promoter region and polymorphisms. Blood Cells Mol Dis 24: 199-215.
-
(1998)
Blood Cells Mol Dis
, vol.24
, pp. 199-215
-
-
Lee, P.L.1
Gelbart, T.2
West, C.3
Halloran, C.4
Beutler, E.5
-
18
-
-
19344376879
-
Hypoxia induces changes in expression of isoforms of the divalent metal transporter (DMT1) in rat pheochromocytoma (PC12) cells
-
Lis A, Paradkar PN, Singleton S, Kuo HC, Garrick MD, Roth JA. 2005. Hypoxia induces changes in expression of isoforms of the divalent metal transporter (DMT1) in rat pheochromocytoma (PC12) cells. Biochem Pharmacol 69: 1647-1655.
-
(2005)
Biochem Pharmacol
, vol.69
, pp. 1647-1655
-
-
Lis, A.1
Paradkar, P.N.2
Singleton, S.3
Kuo, H.C.4
Garrick, M.D.5
Roth, J.A.6
-
19
-
-
0000655498
-
Identification of a hypoxia response element in the transferrin receptor gene
-
Lok CN, Ponka P. 1999. Identification of a hypoxia response element in the transferrin receptor gene. J Biol Chem 274: 24147-24152.
-
(1999)
J Biol Chem
, vol.274
, pp. 24147-24152
-
-
Lok, C.N.1
Ponka, P.2
-
20
-
-
0034647742
-
Role of Hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency
-
Mukhopadhyay CK, Mazumder B, Fox PL. 2000. Role of Hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency. J Bio Chem 275: 21048-21054.
-
(2000)
J Bio Chem
, vol.275
, pp. 21048-21054
-
-
Mukhopadhyay, C.K.1
Mazumder, B.2
Fox, P.L.3
-
21
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G, Chauvet C, Viatte L, Danan JL, Bigard X, Devaux I, Beaumont C, Kahn A, Vaulont S. 2002. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 110: 1037-1044.
-
(2002)
J Clin Invest
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
Danan, J.L.4
Bigard, X.5
Devaux, I.6
Beaumont, C.7
Kahn, A.8
Vaulont, S.9
-
22
-
-
34447120059
-
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)
-
Peyssonnaux C, Zinkernagel AS, Schuepbach RA, Rankin E, Vaulont S, Haase VH, Nizet V, Johnson RS. 2007. Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). J Clin Invest 117: 1926-1932
-
(2007)
J Clin Invest
, vol.117
, pp. 1926-1932
-
-
Peyssonnaux, C.1
Zinkernagel, A.S.2
Schuepbach, R.A.3
Rankin, E.4
Vaulont, S.5
Haase, V.H.6
Nizet, V.7
Johnson, R.S.8
-
23
-
-
0035095564
-
Brain iron transport and neurodegeneration
-
Qian ZM, Shen X. 2001. Brain iron transport and neurodegeneration. Trend Mol Med 7: 103-108.
-
(2001)
Trend Mol Med
, vol.7
, pp. 103-108
-
-
Qian, Z.M.1
Shen, X.2
-
24
-
-
0030728731
-
Iron crosses the endosomal membrane by a carrier-mediated process
-
Qian ZM, Tang PL, Wang Q. 1997. Iron crosses the endosomal membrane by a carrier-mediated process. Prog Biophys Mol Biol 67: 1-15.
-
(1997)
Prog Biophys Mol Biol
, vol.67
, pp. 1-15
-
-
Qian, Z.M.1
Tang, P.L.2
Wang, Q.3
-
25
-
-
0032701114
-
Transferrin receptor on the plasma membrane of cultured rat astrocytes
-
Qian ZM, To Y, Tang PL, Feng YM., 1999. Transferrin receptor on the plasma membrane of cultured rat astrocytes. Exp Brain Res 129: 473-476.
-
(1999)
Exp Brain Res
, vol.129
, pp. 473-476
-
-
Qian, Z.M.1
To, Y.2
Tang, P.L.3
Feng, Y.M.4
-
26
-
-
1642514574
-
Transferrin-bound and transferrin-free iron uptake by the cultured brain astrocytes
-
Qian ZM, Liao QK, To Y, Ke Y, Tsoi YK, Wang GF, Ho KP. 2000. Transferrin-bound and transferrin-free iron uptake by the cultured brain astrocytes. Cell Mol Biol 46: 541-548.
-
(2000)
Cell Mol Biol
, vol.46
, pp. 541-548
-
-
Qian, Z.M.1
Liao, Q.K.2
To, Y.3
Ke, Y.4
Tsoi, Y.K.5
Wang, G.F.6
Ho, K.P.7
-
27
-
-
0028971143
-
MatInd and MatInspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data
-
Quandt K, Frech K, Karas H, Wingender E, Werner T. 1995. MatInd and MatInspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res 23: 4878-4884.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 4878-4884
-
-
Quandt, K.1
Frech, K.2
Karas, H.3
Wingender, E.4
Werner, T.5
-
28
-
-
0030792094
-
Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1
-
Rolfs A, Kvietikova I, Gassmann M, Wenger RH. 1997. Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1. J Bio Chem 272: 20055-20062.
-
(1997)
J Bio Chem
, vol.272
, pp. 20055-20062
-
-
Rolfs, A.1
Kvietikova, I.2
Gassmann, M.3
Wenger, R.H.4
-
29
-
-
0033233243
-
2 homeostasis by hypoxia-inducible factor 1
-
2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 15: 551-578.
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
30
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza GL, Wang GL. 1992. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12: 5447-5454.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
31
-
-
0028068606
-
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
-
Semenza GL, Roth PH, Fang HM, Wang GL. 1994. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem 269: 23757-23763.
-
(1994)
J Biol Chem
, vol.269
, pp. 23757-23763
-
-
Semenza, G.L.1
Roth, P.H.2
Fang, H.M.3
Wang, G.L.4
-
32
-
-
0032530922
-
The G185R mutation disrupts function of the iron transporter Nramp2
-
Su MA, Trenor CC, Fleming JC, Templeton DM. 1998. The G185R mutation disrupts function of the iron transporter Nramp2. Blood 92: 2157-2163.
-
(1998)
Blood
, vol.92
, pp. 2157-2163
-
-
Su, M.A.1
Trenor, C.C.2
Fleming, J.C.3
Templeton, D.M.4
-
33
-
-
0034698023
-
Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in HEp-2 cells
-
Tabuchi M, Yoshimori T, Yamaguchi K, Yoshida T, Kishi F. 2000. Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in HEp-2 cells. J Biol Chem 275: 22220-22228.
-
(2000)
J Biol Chem
, vol.275
, pp. 22220-22228
-
-
Tabuchi, M.1
Yoshimori, T.2
Yamaguchi, K.3
Yoshida, T.4
Kishi, F.5
-
34
-
-
0033588021
-
Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific post-transcriptional regulation
-
Tacchini L, Bianchi L, Bernelli-Zazzera A, Cairo G. 1999. Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific post-transcriptional regulation. J Biol Chem 274: 24142-24146.
-
(1999)
J Biol Chem
, vol.274
, pp. 24142-24146
-
-
Tacchini, L.1
Bianchi, L.2
Bernelli-Zazzera, A.3
Cairo, G.4
-
35
-
-
0028816847
-
Purification and characterization of hypoxia-inducible factor 1
-
Wang GL, Semenza GL. 1995. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 270: 1230-1237.
-
(1995)
J Biol Chem
, vol.270
, pp. 1230-1237
-
-
Wang, G.L.1
Semenza, G.L.2
-
36
-
-
0029051439
-
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
Wang GL, Jiang BH, Rue EA, Semenza GL. 1995. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 92: 5510-5514.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
37
-
-
77955872792
-
Hypoxia regulates the ferrous iron uptake and reactive oxygen species level via divalent metal transporter 1 (DMT1) Exon1B by hypoxia-inducible factor-1
-
Wang D, Wang LH, Zhao Y, Lu YP, Zhu L. 2010. Hypoxia regulates the ferrous iron uptake and reactive oxygen species level via divalent metal transporter 1 (DMT1) Exon1B by hypoxia-inducible factor-1. IUBMB Life 62(8): 629-636.
-
(2010)
IUBMB Life
, vol.62
, Issue.8
, pp. 629-636
-
-
Wang, D.1
Wang, L.H.2
Zhao, Y.3
Lu, Y.P.4
Zhu, L.5
-
38
-
-
22144493303
-
HIF-1α: A master regulator of innate host defenses?
-
Zarember KA, Malech HL. 2005. HIF-1α: A master regulator of innate host defenses? J Clin Invest 115: 1702-1704.
-
(2005)
J Clin Invest
, vol.115
, pp. 1702-1704
-
-
Zarember, K.A.1
Malech, H.L.2
-
39
-
-
42349092684
-
Correlation between the expression of divalent metal transporter 1 and the content of hypoxia-inducible factor-1 in hypoxic HepG2 cells
-
Zhu L, Zhang L, Ke Y, Yang L, Xu CQ, Qian ZM. 2008. Correlation between the expression of divalent metal transporter 1 and the content of hypoxia-inducible factor-1 in hypoxic HepG2 cells. J Cell Mol Med 12: 569-579.
-
(2008)
J Cell Mol Med
, vol.12
, pp. 569-579
-
-
Zhu, L.1
Zhang, L.2
Ke, Y.3
Yang, L.4
Xu, C.Q.5
Qian, Z.M.6
|