Impaired spatial and binocular summation for motion direction discrimination in strabismic amblyopia

Vision Research

Volumn 51, Issue 6, 2011, Pages 577-584

  Thompson, Benjamin ^a,b   Richard, Alby ^c   Churan, Jan ^c   Hess, Robert F ^b   Aaen Stockdale, Craig ^b,d   Pack, Christopher C ^c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

Amblyopia; Binocular summation; Direction discrimination; Motion perception; Spatial summation; Strabismus

Indexed keywords

ADULT; AMBLYOPIA; ARTICLE; BINOCULAR VISION; CLINICAL ARTICLE; CONTROLLED STUDY; EYE DOMINANCE; FEMALE; HUMAN; MALE; MONOCULAR VISION; MOVEMENT PERCEPTION; PRIORITY JOURNAL; SIGNAL NOISE RATIO; SPATIAL SUMMATION; STIMULUS RESPONSE; TASK PERFORMANCE; VISUAL ACUITY; VISUAL STIMULATION;

ADULT; AMBLYOPIA; ANALYSIS OF VARIANCE; CONTRAST SENSITIVITY; DISCRIMINATION (PSYCHOLOGY); FEMALE; HUMANS; MALE; MIDDLE AGED; MOTION PERCEPTION; SIZE PERCEPTION; STRABISMUS; VISION, BINOCULAR; VISION, MONOCULAR; YOUNG ADULT;

EID: 79952701030     PISSN: 00426989     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.visres.2011.02.001     Document Type: Article

References (83)

1. Aaen-Stockdale C., Hess R.F. The amblyopic deficit for global motion is spatial scale invariant. Vision Research 2008, 48(19):1965-1971.
2. Aaen-Stockdale C., Ledgeway T., Hess R.F. Second-order optic flow deficits in amblyopia. Investigative Ophthalmology and Visual Science 2007, 48(12):5532-5538.
3. Aaen-Stockdale C.R., Thompson B., Huang P.C., Hess R.F. Low-level mechanisms may contribute to paradoxical motion percepts. Journal Vision 2009, 9(5):1-14.
4. Albrecht D.G., Hamilton D.B. Striate cortex of monkey and cat: Contrast response function. Journal of Neurophysiology 1982, 48(1):217-237.
5. Anderson S.J., Swettenham J.B. Neuroimaging in human amblyopia. Strabismus 2006, 14(1):21-35.
6. Baker D.H., Meese T.S., Hess R.F. Contrast masking in strabismic amblyopia: Attenuation, noise, interocular suppression and binocular summation. Vision Research 2008, 48(15):1625-1640.
7. Barnes G.R., Hess R.F., Dumoulin S.O., Achtman R.L., Pike G.B. The cortical deficit in humans with strabismic amblyopia. Journal of Physiology (Lond) 2001, 533:281-297.
8. Barrett B.T., Bradley A., McGraw P.V. Understanding the neural basis of amblyopia. Neuroscientist 2004, 10(2):106-117.
9. Barrett B.T., Pacey I.E., Bradley A., Thibos L.N., Morrill P. Nonveridical visual perception in human amblyopia. Investigative Ophthalmology and Visual Science 2003, 44(4):1555-1567.
10. Bonhomme G.R., Liu G.T., Miki A., Francis E., Dobre M.C., Modestino E.J., et al. Decreased cortical activation in response to a motion stimulus in anisometropic amblyopic eyes using functional magnetic resonance imaging. J AAPOS 2006, 10(6):540-546.
11. Bradley A., Freeman R.D. Contrast sensitivity in anisometropic amblyopia. Investigative Ophthalmology and Visual Science 1981, 21(3):467-476.
12. Brainard D.H. The psychophysics toolbox. Spatial Vision 1997, 10(4):433-436.
13. Britten K.H., Shadlen M.N., Newsome W.T., Movshon J.A. The analysis of visual motion: A comparison of neuronal and psychophysical performance. Journal of Neuroscience 1992, 12(12):4745-4765.
14. Buckingham T., Watkins R., Bansal P., Bamford K. Hyperacuity thresholds for oscillatory movement are abnormal in strabismic and anisometropic amblyopes. Optometry and Vision Science 1991, 68(5):351-356.
15. Campbell F.W., Green D.G. Monocular versus binocular visual acuity. Nature 1965, 208(5006):191.
16. Cavanagh P., Alvarez G.A. Tracking multiple targets with multifocal attention. Trends in Cognitive Sciences 2005, 9(7):349-354.
17. Chandna A., Pennefather P.M., Kovacs I., Norcia A.M. Contour integration deficits in anisometropic amblyopia. Investigative Ophthalmology and Visual Science 2001, 42(3):875-878.
18. Churan J., Khawaja F.A., Tsui J.M., Pack C.C. Brief motion stimuli preferentially activate surround-suppressed neurons in macaque visual area MT. Current Biology 2008, 18(22):R1051-1052.
19. Churan J., Richard A.G., Pack C.C. Interaction of spatial and temporal factors in psychophysical estimates of surround suppression. Journal of Vision 2009, 9(4):1-15.
20. Constantinescu T., Schmidt L., Watson R., Hess R.F. A residual deficit for global motion processing after acuity recovery in deprivation amblyopia. Investigative Ophthalmology and Visual Science 2005, 46(8):3008-3012.
21. Derrington A.M., Goddard P.A. Failure of motion discrimination at high contrasts - evidence for saturation. Vision Research 1989, 29(12):1767-1776.
22. Ellemberg D., Lewis T.L., Maurer D., Brar S., Brent H.P. Better perception of global motion after monocular than after binocular deprivation. Vision Research 2002, 42(2):169-179.
23. El-Shamayleh Y., Kiorpes L., Kohn A., Movshon J.A. Visual motion processing by neurons in area MT of macaque monkeys with experimental amblyopia. Journal of Neuroscience 2010, 30(36):12198-12209.
24. Georgeson M.A., Meese T.S. Binocular summation at contrast threshold: A new look. Perception 2005, 34:138.
25. Giaschi D.E., Regan D., Kraft S.P., Hong X.H. Defective processing of motion-defined form in the fellow eye of patients with unilateral amblyopia. Investigative Ophthalmology and Visual Science 1992, 33(8):2483-2489.
26. Glasser D.M., Tadin D. Low-level mechanisms do not explain paradoxical motion percepts. Journal of Vision 2010, 10(4).
27. Heeger D.J. Normalization of cell responses in cat striate cortex. Visual Neuroscience 1992, 9(2):181-197.
28. Hess R.F. Contrast sensitivity assessment of functional amblyopia in humans. Transactions of the Ophthalmological Societies of the United Kingdom 1979, 99(3):391-397.
29. Hess R.F., Anderson S.J. Motion sensitivity and spatial undersampling in amblyopia. Vision Research 1993, 33(7):881-896.
30. Hess R.F., Demanins R. Contour integration in anisometropic amblyopia. Vision Research 1998, 38(6):889-894.
31. Hess R.F., Demanins R., Bex P.J. A reduced motion aftereffect in strabismic amblyopia. Vision Research 1997, 37(10):1303-1311.
32. Hess R.F., Howell E.R. The threshold contrast sensitivity function in strabismic amblyopia: Evidence for a two type classification. Vision Research 1977, 17(9):1049-1055.
33. Hess R.F., Howell E.R., Kitchin J.E. On the relationship between pattern and movement perception in strabismic amblyopia. Vision Research 1978, 18(4):375-377.
34. Hess R.F., Li X., Lu G., Thompson B., Hansen B.C. The contrast dependence of the cortical fMRI deficit in amblyopia: A selective loss at higher contrasts. Human Brain Mapping 2010, 31(8):1233-1248.
35. Hess R.F., Li X., Mansouri B., Thompson B., Hansen B.C. Selectivity as well as sensitivity loss characterizes the cortical spatial frequency deficit in amblyopia. Human Brain Mapping 2009, 30(12):4054-4069.
36. Hess R.F., Mansouri B., Dakin S.C., Allen H.A. Integration of local motion is normal in amblyopia. **J Opt Soc Am A Opt Image Sci Vis 2006, 23(5):986-992.
37. Ho C.S., Giaschi D.E. Deficient maximum motion displacement in amblyopia. Vision Research 2006, 46(28):4595-4603.
38. Ho C.S., Giaschi D.E. Stereopsis-dependent deficits in maximum motion displacement in strabismic and anisometropic amblyopia. Vision Research 2007, 47(21):2778-2785.
39. Ho C.S., Giaschi D.E. Low- and high-level motion perception deficits in anisometropic and strabismic amblyopia: Evidence from fMRI. Vision Research 2009, 49(24):2891-2901.
40. Ho C.S., Giaschi D.E., Boden C., Dougherty R., Cline R., Lyons C. Deficient motion perception in the fellow eye of amblyopic children. Vision Research 2005, 45(12):1615-1627.
41. Ho C.S., Paul P.S., Asirvatham A., Cavanagh P., Cline R., Giaschi D.E. Abnormal spatial selection and tracking in children with amblyopia. Vision Research 2006, 46(19):3274-3283.
42. Holmes J.M., Clarke M.P. Amblyopia. Lancet 2006, 367(9519):1343-1351.
43. Holopigian K., Blake R., Greenwald M.J. Clinical suppression and amblyopia. Investigative Ophthalmology and Visual Science 1988, 29(3):444-451.
44. Hood A.S., Morrison J.D. The dependence of binocular contrast sensitivities on binocular single vision in normal and amblyopic human subjects. Journal of Physiology 2002, 540(Pt 2):607-622.
45. Kaernbach C. Simple adaptive testing with the weighted up-down method. Perception & Psychophysics 1991, 49(3):227-229.
46. Kelly S.L., Buckingham T.J. Movement hyperacuity in childhood amblyopia. British Journal of Ophthalmology 1998, 82(9):991-995.
47. Kiorpes L. Visual processing in amblyopia: animal studies. Strabismus 2006, 14(1):3-10.
48. Kiorpes L., Kiper D.C., O'Keefe L.P., Cavanaugh J.R., Movshon J.A. Neuronal correlates of amblyopia in the visual cortex of macaque monkeys with experimental strabismus and anisometropia. Journal of Neuroscience 1998, 18(16):6411-6424.
49. Kiorpes L., McKee S.P. Neural mechanisms underlying amblyopia. Current Opinion in Neurobiology 1999, 9(4):480-486.
50. Kiorpes L., Tang C., Movshon J.A. Sensitivity to visual motion in amblyopic macaque monkeys. Visual Neuroscience 2006, 23(2):247-256.
51. Kozma P., Kiorpes L. Contour integration in amblyopic monkeys. Visual Neuroscience 2003, 20(5):577-588.
52. Lema S.A., Blake R. Binocular summation in normal and stereoblind humans. Vision Research 1977, 17(6):691-695.
53. Levi D.M. Visual processing in amblyopia: human studies. Strabismus 2006, 14(1):11-19.
54. Levi D.M., Harwerth R.S. Contrast sensitivity in amblyopia due to stimulus deprivation. British Journal of Ophthalmology 1980, 64(1):15-20.
55. Levi D.M., Harwerth R.S., Manny R.E. Suprathreshold spatial frequency detection and binocular interaction in strabismic and anisometropic amblyopia. Investigative Ophthalmology and Visual Science 1979, 18(7):714-725.
56. Levi D.M., Harwerth R.S., Smith E.L. Binocular interactions in normal and anomalous binocular vision. Documenta Ophthalmologica 1980, 49(2):303-324.
57. Levi D.M., Klein S.A., Aitsebaomo P. Detection and discrimination of the direction of motion in central and peripheral vision of normal and amblyopic observers. Vision Research 1984, 24(8):789-800.
58. Levi D.M., Pass A.F., Manny R.E. Binocular interactions in normal and anomalous binocular vision: Effects of flicker. British Journal of Ophthalmology 1982, 66(1):57-63.
59. Mansouri B., Hess R.F. The global processing deficit in amblyopia involves noise segregation. Vision Research 2006, 46(24):4104-4117.
60. Mansouri B., Thompson B., Hess R.F. Measurement of suprathreshold binocular interactions in amblyopia. Vision Research 2008, 48(28):2775-2784.
61. Maunsell J.H., Nealey T.A., DePriest D.D. Magnocellular and parvocellular contributions to responses in the middle temporal visual area (MT) of the macaque monkey. Journal of Neuroscience 1990, 10(10):3323-3334.
62. Meese T.S., Georgeson M.A., Baker D.H. Binocular contrast vision at and above threshold. Journal of Vision 2006, 6(11):1224-1243.
63. Meese T., Georgeson N., Hess R. Binocular summation, interocular suppression, and contrast gain control: psychophysical model and data. Perception 2004, 33:41.
64. Movshon J.A., Eggers H.M., Gizzi M.S., Hendrickson A.E., Kiorpes L., Boothe R.G. Effects of early unilateral blur on the macaque's visual system. III. Physiological observations. Journal of Neuroscience 1987, 7(5):1340-1351.
65. Muckli L., Kiess S., Tonhausen N., Singer W., Goebel R., Sireteanu R. Cerebral correlates of impaired grating perception in individual, psychophysically assessed human amblyopes. Vision Research 2006, 46(4):506-526.
66. Nakayama K., Silverman G.H. Detection and discrimination of sinusoidal grating displacements. Journal of the Optical Society of America A. Optics and Image Science 1985, 2(2):267-274.
67. Newsome W.T., Pare E.B. A selective impairment of motion perception following lesions of the middle temporal visual area (MT). Journal of Neuroscience 1988, 8(6):2201-2211.
68. Pack C.C., Conway B.R., Born R.T., Livingstone M.S. Spatiotemporal structure of nonlinear subunits in macaque visual cortex. Journal of Neuroscience 2006, 26(3):893-907.
69. Pack C.C., Hunter J.N., Born R.T. Contrast dependence of suppressive influences in cortical area MT of alert macaque. Journal of Neurophysiology 2005, 93(3):1809-1815.
70. Pardhan S., Whitaker A. Binocular summation in the fovea and peripheral field of anisometropic amblyopes. Current Eye Research 2000, 20(1):35-44.
71. Pelli D.G. The VideoToolbox software for visual psychophysics: Transforming numbers into movies. Spatial Vision 1997, 10(4):437-442.
72. Rose D. Monocular versus binocular contrast thresholds for movement and pattern. Perception 1978, 7(2):195-200.
73. Rose D. The binocular: Monocular sensitivity ratio for movement detection varies with temporal frequency. Perception 1980, 9(5):577-580.
74. Rosenbach O. Vorherrschaft beim binikularen sehen. Munch Med Wochenschr 1903, 30:1290-1292.
75. Schor C.M., Levi D.M. Direction selectivity for perceived motion in strabismic and anisometropoic amblyopia. Investigative Ophthalmology and Visual Science 1980, 19(9):1094-1104.
76. Simmers A.J., Ledgeway T., Hess R.F., McGraw P.V. Deficits to global motion processing in human amblyopia. Vision Research 2003, 43(6):729-738.
77. Simmers A.J., Ledgeway T., Mansouri B., Hutchinson C.V., Hess R.F. The extent of the dorsal extra-striate deficit in amblyopia. Vision Research 2006, 46(16):2571-2580.
78. Steinman S.B., Levi D.M., Mckee S.P. Discrimination of time and velocity in the amblyopic visual-system. Clinical Vision Sciences 1988, 2(4):265-276.
79. Tadin D., Lappin J.S., Gilroy L.A., Blake R. Perceptual consequences of centre-surround antagonism in visual motion processing. Nature 2003, 424(6946):312-315.
80. Thompson B., Aaen-Stockdale C.R., Mansouri B., Hess R.F. Plaid perception is only subtly impaired in strabismic amblyopia. Vision Research 2008, 48(11):1307-1314.
81. Thompson, B., Villeneuve, M. Y., Casanova, C., & Hess, R. F. (2010). Pattern motion responses in the visual cortex of humans with amblyopia. Program no. 731.5, 2010 Society for neuroscience meeting planner (San Diego, CA: Society for Neuroscience, 2010. Online.
82. Thompson B., Hansen B.C., Hess R.F., Troje N.F. Amblyopic perception of biological motion. Journal of Vision 2007, 7(9):485.
83. Wallisch P., Kumbhani R.D. Can major depression improve the perception of visual motion?. Journal of Neuroscience 2009, 29(46):14381-14382.