-
1
-
-
42149116231
-
Vitro and in vivo protection against the highly pathogenic H5N1 influenza virus by an antisense phosphorothioate oligonucleotide
-
Duan M, Zhou Z, Lin RX, Yang J, Xia XZ, Wang SQ. In vitro and in vivo protection against the highly pathogenic H5N1 influenza virus by an antisense phosphorothioate oligonucleotide. Antivir Ther 2008;13(1):109-14.
-
(2008)
Antivir Ther
, vol.13
, Issue.1
, pp. 109-114
-
-
Duan, M.1
Zhou, Z.2
Lin, R.X.3
Yang, J.4
Xia, X.Z.5
Wang, S.Q.6
-
2
-
-
70449724590
-
Inhibition of highly pathogenic avian influenza virus H5N1 replication by the small interfering RNA targeting polymerase A gene
-
Zhang W, Wang CY, Yang ST,Qin C, Hu JL, Xia XZ. Inhibition of highly pathogenic avian influenza virus H5N1 replication by the small interfering RNA targeting polymerase A gene. Biochem Biophys Res Commun 2009;390(3):421-6.
-
(2009)
Biochem Biophys Res Commun
, vol.390
, Issue.3
, pp. 421-426
-
-
Zhang, W.1
Wang, C.Y.2
Yang, S.T.3
Qin, C.4
Hu, J.L.5
Xia, X.Z.6
-
3
-
-
0033014533
-
Anti-senseoligonucleotides directed again sttheviral RNA polymerase gene enhance survival of mice infected with influenza A.
-
Mizuta T, Fujiwara M, Hatta T, Abe T, Miyano-Kurosaki N, Shigeta S, et al. Anti-senseoligonucleotides directed again sttheviral RNA polymerase gene enhance survival of mice infected with influenza A. Nat Biotechnol 1999;17(6):583-7.
-
(1999)
Nat Biotechnol
, vol.17
, Issue.6
, pp. 583-587
-
-
Mizuta, T.1
Fujiwara, M.2
Hatta, T.3
Abe, T.4
Miyano-Kurosaki, N.5
Shigeta, S.6
-
4
-
-
36249003925
-
Inhibition of highly pathogenic avian H5N1 influenza virus replication by RNA oligonucleotides targeting NS1 gene
-
Wu Y, Zhang G, Li Y, Jin Y, Dale R, Sun LQ, et al. Inhibition of highly pathogenic avian H5N1 influenza virus replication by RNA oligonucleotides targeting NS1 gene. Biochem Biophys Res Commun 2008;365(2):369-74.
-
(2008)
Biochem Biophys Res Commun
, vol.365
, Issue.2
, pp. 369-374
-
-
Wu, Y.1
Zhang, G.2
Li, Y.3
Jin, Y.4
Dale, R.5
Sun, L.Q.6
-
5
-
-
33947589836
-
Nucleic acid-based antiviral drugs against seasonal and avian influenza viruses
-
Wong JP, Christopher ME, Salazar AM, Dale RM, Sun LQ, Wang M. Nucleic acid-based antiviral drugs against seasonal and avian influenza viruses. Vaccine 2007;25(16):3175-8.
-
(2007)
Vaccine
, vol.25
, Issue.16
, pp. 3175-3178
-
-
Wong, J.P.1
Christopher, M.E.2
Salazar, A.M.3
Dale, R.M.4
Sun, L.Q.5
Wang, M.6
-
6
-
-
38049161918
-
RNAi for treating hepatitis B viral infection
-
Chen Y, Cheng G, Mahato RI. RNAi for treating hepatitis B viral infection. Pharm Res 2008;25(1):72-86.
-
(2008)
Pharm Res
, vol.25
, Issue.1
, pp. 72-86
-
-
Chen, Y.1
Cheng, G.2
Mahato, R.I.3
-
7
-
-
23844474160
-
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
-
Song E, Zhu P, Lee SK, Chowdhury D, Kussman S, Dykxhoorn DM, et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat Biotechnol 2005;23(6):709-17.
-
(2005)
Nat Biotechnol
, vol.23
, Issue.6
, pp. 709-717
-
-
Song, E.1
Zhu, P.2
Lee, S.K.3
Chowdhury, D.4
Kussman, S.5
Dykxhoorn, D.M.6
-
8
-
-
77952429309
-
Generation and characterization of a fusion protein of single-chain fragment variable antibody against hemagglutinin antigen of avian influenza virus and truncated protamine
-
Zhang T, Wang CY, Zhang W, Gao YW, Yang ST, Wang TC, et al. Generation and characterization of a fusion protein of single-chain fragment variable antibody against hemagglutinin antigen of avian influenza virus and truncated protamine. Vaccine 2010;28(23):3949-55.
-
(2010)
Vaccine
, vol.28
, Issue.23
, pp. 3949-3955
-
-
Zhang, T.1
Wang, C.Y.2
Zhang, W.3
Gao, Y.W.4
Yang, S.T.5
Wang, T.C.6
-
9
-
-
34748893680
-
Influence of strain, dose of virus, and age at inoculation on subgroup J avian leukosis virus persistence, antibody response, and oncogenicity in commercial meat-type chickens
-
Pandiri AR, Reed WM, Mays JK, Fadly AM. Influence of strain, dose of virus, and age at inoculation on subgroup J avian leukosis virus persistence, antibody response, and oncogenicity in commercial meat-type chickens. Avian Dis 2007;51(3):725-32.
-
(2007)
Avian Dis
, vol.51
, Issue.3
, pp. 725-732
-
-
Pandiri, A.R.1
Reed, W.M.2
Mays, J.K.3
Fadly, A.M.4
-
10
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
Zamecnik P, Stephenson M. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc Natl Acad Sci USA 1978;75(1):280-4.
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, Issue.1
, pp. 280-284
-
-
Zamecnik, P.1
Stephenson, M.2
-
11
-
-
34548637012
-
Effective small interfering RNAs targeting matrix and nucleocapsid protein gene inhibit influenza A virus replication in cells and mice
-
Zhou H, Jin M, Yu Z, Xu X, Peng Y, Wu H, et al. Effective small interfering RNAs targeting matrix and nucleocapsid protein gene inhibit influenza A virus replication in cells and mice. Antiviral Res 2007;76(2):186-93.
-
(2007)
Antiviral Res
, vol.76
, Issue.2
, pp. 186-193
-
-
Zhou, H.1
Jin, M.2
Yu, Z.3
Xu, X.4
Peng, Y.5
Wu, H.6
-
12
-
-
76949094519
-
Effective siR-NAs inhibit the replication of novel influenza A (H1N1) virus
-
Zhiqiang W, Yaowu Y, Fan Y, Jian Y, Yongfeng H, Lina Z, et al. Effective siR-NAs inhibit the replication of novel influenza A (H1N1) virus. Antiviral Res 2010:559-61.
-
(2010)
Antiviral Res
, pp. 559-561
-
-
Zhiqiang, W.1
Yaowu, Y.2
Fan, Y.3
Jian, Y.4
Yongfeng, H.5
Lina, Z.6
-
13
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
Zamecnik PC, Stephenson ML. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc Natl Acad Sci USA 1978;75(1):280-4.
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, Issue.1
, pp. 280-284
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
14
-
-
14844290876
-
Prophylaxis of acute respiratory virus infections using nucleic acid-based drugs
-
Wong JP, Nagata LP, Christopher ME, Salazar AM, Dale RM. Prophylaxis of acute respiratory virus infections using nucleic acid-based drugs. Vaccine 2005;23(17-18):2266-8.
-
(2005)
Vaccine
, vol.23
, Issue.17-18
, pp. 2266-2268
-
-
Wong, J.P.1
Nagata, L.P.2
Christopher, M.E.3
Salazar, A.M.4
Dale, R.M.5
-
15
-
-
0033379680
-
Fomivirsen -a phosphorothioate oligonucleotide for the treatment of CMV retinitis
-
de Smet MD, Meenken CJ, van den Horn GJ. Fomivirsen -a phosphorothioate oligonucleotide for the treatment of CMV retinitis. Ocul Immunol Inflamm 1999;7(3-4):189-98.
-
(1999)
Ocul Immunol Inflamm
, vol.7
, Issue.3-4
, pp. 189-198
-
-
de Smet, M.D.1
Meenken, C.J.2
van den Horn, G.J.3
-
16
-
-
0037418322
-
RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription
-
Ge Q,McManus MT, Nguyen T, Shen CH, Sharp PA, Eisen HN, etal. RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci USA 2003;100(5):2718-23.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.5
, pp. 2718-2723
-
-
Ge, Q.1
McManus, M.T.2
Nguyen, T.3
Shen, C.H.4
Sharp, P.A.5
Eisen, H.N.6
-
17
-
-
0025301411
-
Inhibition of influenza virus replication by phosphorothioate oligodeoxynucleotides
-
Leiter JM, Agrawal S, Palese P, Zamecnik PC. Inhibition of influenza virus replication by phosphorothioate oligodeoxynucleotides. Proc Natl Acad Sci USA 1990;87(9):3430-4.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, Issue.9
, pp. 3430-3434
-
-
Leiter, J.M.1
Agrawal, S.2
Palese, P.3
Zamecnik, P.C.4
-
18
-
-
67249100913
-
Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
-
Yuan P, Bartlam M, Lou Z, Chen S, Zhou J, He X, et al. Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site. Nature 2009;458(7240):909-13.
-
(2009)
Nature
, vol.458
, Issue.7240
, pp. 909-913
-
-
Yuan, P.1
Bartlam, M.2
Lou, Z.3
Chen, S.4
Zhou, J.5
He, X.6
-
19
-
-
0033976989
-
The replication activity of influenza virus polymerase is linked to the capacity of the PA subunit to induce proteolysis
-
Perales B, Sanz-Ezquerro JJ, Gastaminza P, Ortega J, Santaren JF, Ortin J, et al. The replication activity of influenza virus polymerase is linked to the capacity of the PA subunit to induce proteolysis. J Virol 2000;74(3):1307-12.
-
(2000)
J Virol
, vol.74
, Issue.3
, pp. 1307-1312
-
-
Perales, B.1
Sanz-Ezquerro, J.J.2
Gastaminza, P.3
Ortega, J.4
Santaren, J.F.5
Ortin, J.6
-
20
-
-
0038371106
-
Threonine 157 of influenza virusPApolymerase subunit modulates RNA replicationininfectious viruses
-
Huarte M, Falcon A, Nakaya Y, Ortin J, Garcia-Sastre A, Nieto A. Threonine 157 of influenza virusPApolymerase subunit modulates RNA replicationininfectious viruses. J Virol 2003;77(10):6007-13.
-
(2003)
J Virol
, vol.77
, Issue.10
, pp. 6007-6013
-
-
Huarte, M.1
Falcon, A.2
Nakaya, Y.3
Ortin, J.4
Garcia-Sastre, A.5
Nieto, A.6
-
21
-
-
36549071098
-
Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding
-
Maier HJ, Kashiwagi T, Hara K, Brownlee GG. Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding. Virology 2008;370(1):194-204.
-
(2008)
Virology
, vol.370
, Issue.1
, pp. 194-204
-
-
Maier, H.J.1
Kashiwagi, T.2
Hara, K.3
Brownlee, G.G.4
-
22
-
-
0036705723
-
Tumor-targeting, systemically delivered antisense HER-2 chemosensitizes human breast cancer xenografts irrespective of HER-2 levels
-
Rait AS, Pirollo KF, Xiang L, Ulick D, Chang EH. Tumor-targeting, systemically delivered antisense HER-2 chemosensitizes human breast cancer xenografts irrespective of HER-2 levels. Mol Med 2002;8(8):475-86.
-
(2002)
Mol Med
, vol.8
, Issue.8
, pp. 475-486
-
-
Rait, A.S.1
Pirollo, K.F.2
Xiang, L.3
Ulick, D.4
Chang, E.H.5
-
23
-
-
0036860003
-
Efficient intracel-lular delivery of oligonucleotides formulated in folate receptor-targeted lipid vesicles
-
Zhou W, Yuan X, Wilson A, Yang L, Mokotoff M, Pitt B, et al. Efficient intracel-lular delivery of oligonucleotides formulated in folate receptor-targeted lipid vesicles. Bioconjug Chem 2002;13(6):1220-5.
-
(2002)
Bioconjug Chem
, vol.13
, Issue.6
, pp. 1220-1225
-
-
Zhou, W.1
Yuan, X.2
Wilson, A.3
Yang, L.4
Mokotoff, M.5
Pitt, B.6
-
24
-
-
33847168570
-
Folate receptor targeted delivery of polyelectrolyte complex micelles prepared from ODN-PEG-folate conjugate and cationic lipids
-
Kim SH, Jeong JH, Mok H, Lee SH, Kim SW, Park TG. Folate receptor targeted delivery of polyelectrolyte complex micelles prepared from ODN-PEG-folate conjugate and cationic lipids. Biotechnol Prog 2007;23(1):232-7.
-
(2007)
Biotechnol Prog
, vol.23
, Issue.1
, pp. 232-237
-
-
Kim, S.H.1
Jeong, J.H.2
Mok, H.3
Lee, S.H.4
Kim, S.W.5
Park, T.G.6
-
26
-
-
30644473108
-
Antibody-directed cell-type-specific delivery of siRNA
-
Vornlocher HP. Antibody-directed cell-type-specific delivery of siRNA. Trends Mol Med 2006;12(1):1-3.
-
(2006)
Trends Mol Med
, vol.12
, Issue.1
, pp. 1-3
-
-
Vornlocher, H.P.1
-
27
-
-
34547403273
-
Targeted inhibition of HBV gene expression by single-chain antibody mediated small interfering RNA delivery
-
Wen WH, Liu JY, Qin WJ, Zhao J, Wang T, Jia LT, et al. Targeted inhibition of HBV gene expression by single-chain antibody mediated small interfering RNA delivery. Hepatology 2007;46(1):84-94.
-
(2007)
Hepatology
, vol.46
, Issue.1
, pp. 84-94
-
-
Wen, W.H.1
Liu, J.Y.2
Qin, W.J.3
Zhao, J.4
Wang, T.5
Jia, L.T.6
-
28
-
-
0033079822
-
Treatment of influenza virus-infected SCID micewith nonneutralizing antibodies specificfor the transmembrane proteins matrix 2 and neuraminidase reduces the pulmonary virus titer but fails to clear the infection
-
Mozdzanowska K, Maiese K, Furchner M, Gerhard W. Treatment of influenza virus-infected SCID micewith nonneutralizing antibodies specificfor the transmembrane proteins matrix 2 and neuraminidase reduces the pulmonary virus titer but fails to clear the infection. Virology 1999;254(1):138-46.
-
(1999)
Virology
, vol.254
, Issue.1
, pp. 138-146
-
-
Mozdzanowska, K.1
Maiese, K.2
Furchner, M.3
Gerhard, W.4
-
29
-
-
0025743216
-
Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice
-
Agrawal S,Temsamani J, Tang J. Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice. Proc Natl Acad Sci USA 1991;88(17):7595-9.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, Issue.17
, pp. 7595-7599
-
-
Agrawal, S.1
Temsamani, J.2
Tang, J.3
-
30
-
-
0027786912
-
Disposition of the 14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats
-
Cossum PA, Sasmor H, Dellinger D, Truong L, Cummins L, Owens SR, et al. Disposition of the 14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats. J Pharmacol Exp Ther 1993;267(3):1181-90.
-
(1993)
J Pharmacol Exp Ther
, vol.267
, Issue.3
, pp. 1181-1190
-
-
Cossum, P.A.1
Sasmor, H.2
Dellinger, D.3
Truong, L.4
Cummins, L.5
Owens, S.R.6
-
31
-
-
33846241302
-
Multivariate toxicity screening of liposomal formulations on a human buccal cell line
-
Smistad G, Jacobsen J, Sande SA. Multivariate toxicity screening of liposomal formulations on a human buccal cell line. Int J Pharm 2007;330(1-2):14-22.
-
(2007)
Int J Pharm
, vol.330
, Issue.1-2
, pp. 14-22
-
-
Smistad, G.1
Jacobsen, J.2
Sande, S.A.3
-
32
-
-
0034774810
-
Efficiency and toxicity of liposome-mediated gene transfer to corneal endothelial cells
-
Pleyer U, Groth D, Hinz B, Keil O, Bertelmann E, Rieck P, et al. Efficiency and toxicity of liposome-mediated gene transfer to corneal endothelial cells. Exp Eye Res 2001;73(1):1-7.
-
(2001)
Exp Eye Res
, vol.73
, Issue.1
, pp. 1-7
-
-
Pleyer, U.1
Groth, D.2
Hinz, B.3
Keil, O.4
Bertelmann, E.5
Rieck, P.6
-
33
-
-
47249138782
-
Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides
-
Juliano R, Alam MR, Dixit V, Kang H. Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides. Nucleic Acids Res 2008;36(12):4158-71.
-
(2008)
Nucleic Acids Res
, vol.36
, Issue.12
, pp. 4158-4171
-
-
Juliano, R.1
Alam, M.R.2
Dixit, V.3
Kang, H.4
-
34
-
-
0032960982
-
Antisense pharmacodynamics: Critical issues in the transport and delivery of antisense oligonucleotides
-
Juliano RL, Alahari S, Yoo H, Kole R, Cho M. Antisense pharmacodynamics: critical issues in the transport and delivery of antisense oligonucleotides. Pharm Res 1999;16(4):494-502.
-
(1999)
Pharm Res
, vol.16
, Issue.4
, pp. 494-502
-
-
Juliano, R.L.1
Alahari, S.2
Yoo, H.3
Kole, R.4
Cho, M.5
-
35
-
-
24144463114
-
Progress in the delivery of therapeutic oligonucleotides: Organ/cellular distribution and targeted delivery of oligonucleotides in vivo
-
Wang L, Prakash RK, Stein CA, Koehn RK, Ruffner DE. Progress in the delivery of therapeutic oligonucleotides: organ/cellular distribution and targeted delivery of oligonucleotides in vivo. Antisense Nucleic Acid Drug Dev 2003;13(3):169-89.
-
(2003)
Antisense Nucleic Acid Drug Dev
, vol.13
, Issue.3
, pp. 169-189
-
-
Wang, L.1
Prakash, R.K.2
Stein, C.A.3
Koehn, R.K.4
Ruffner, D.E.5
-
36
-
-
43349103903
-
Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis
-
Alam MR, Dixit V, Kang H, Li ZB, Chen X, Trejo J, et al. Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis. Nucleic Acids Res 2008;36(8):2764-76.
-
(2008)
Nucleic Acids Res
, vol.36
, Issue.8
, pp. 2764-2776
-
-
Alam, M.R.1
Dixit, V.2
Kang, H.3
Li, Z.B.4
Chen, X.5
Trejo, J.6
-
37
-
-
9144227511
-
DNA aptamer prevents influenza infection by blocking the receptor binding region of the viral hemagglutinin
-
Jeon SH, Kayhan B, Ben-Yedidia T, Arnon RA. DNA aptamer prevents influenza infection by blocking the receptor binding region of the viral hemagglutinin. J Biol Chem 2004;279(46):48410-9.
-
(2004)
J Biol Chem
, vol.279
, Issue.46
, pp. 48410-48419
-
-
Jeon, S.H.1
Kayhan, B.2
Ben-Yedidia, T.3
Arnon, R.A.4
-
39
-
-
33745746584
-
An efficient RNA aptamer against human influenza B virus hemagglutinin
-
Gopinath SC, Sakamaki Y, Kawasaki K, Kumar PK. An efficient RNA aptamer against human influenza B virus hemagglutinin. J Biochem 2006;139(5):837-46.
-
(2006)
J Biochem
, vol.139
, Issue.5
, pp. 837-846
-
-
Gopinath, S.C.1
Sakamaki, Y.2
Kawasaki, K.3
Kumar, P.K.4
|