Maternal exposure to polychlorinated biphenyls and the secondary sex ratio: An occupational cohort study

Environmental Health: A Global Access Science Source

Volumn 10, Issue 1, 2011, Pages

  Rocheleau, Carissa M ^a   Bertke, Stephen J ^a,b   Deddens, James A ^a,b   Ruder, Avima M ^a   Lawson, Christina C ^a   Waters, Martha A ^a   Hopf, Nancy B ^a,c   Riggs, Margaret A ^a,d   Whelan, Elizabeth A ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ORAL CONTRACEPTIVE AGENT; POLYCHLORINATED BIPHENYL;

COHORT ANALYSIS; LOGISTICS; MATERNAL HEALTH; MULTIVARIATE ANALYSIS; OCCUPATIONAL EXPOSURE; PCB; POLLUTION EFFECT; POLLUTION EXPOSURE; SEX RATIO; SPATIOTEMPORAL ANALYSIS;

ADULT; ARTICLE; BODY MASS; COHORT ANALYSIS; CONCEPTION; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; INFANT; MALE; MATERNAL AGE; OCCUPATIONAL EXPOSURE; ORAL CONTRACEPTION; PRENATAL EXPOSURE; PRIMIPARA; PRIORITY JOURNAL; RACE; SEX RATIO; SMOKING; ADOLESCENT; CHEMICAL INDUSTRY; MULTIVARIATE ANALYSIS; QUESTIONNAIRE; RETROSPECTIVE STUDY; UNITED STATES;

UNITED STATES;

ADOLESCENT; ADULT; CHEMICAL INDUSTRY; COHORT STUDIES; FEMALE; HUMANS; INDIANA; MALE; MASSACHUSETTS; MATERNAL EXPOSURE; MULTIVARIATE ANALYSIS; NEW YORK; OCCUPATIONAL EXPOSURE; POLYCHLORINATED BIPHENYLS; QUESTIONNAIRES; RETROSPECTIVE STUDIES; SEX RATIO; YOUNG ADULT;

EID: 79952698603     PISSN: None     EISSN: 1476069X     Source Type: Journal    
DOI: 10.1186/1476-069X-10-20     Document Type: Article

References (62)

1. Agency for Toxic Substances and Disease Register (ATSDR): Toxicological profile for polychlorinated biphenyls (update). Atlanta 2000.
2. Carrie J, Wang F, Sanei H, Macdonald RW, Outridge PM, Stern GA: Increasing contaminant burdens in an arctic fish, Burbot (Lota lota), in a warming climate. Environ Sci Technol 2009, 44:316-322.
3. Hu D, Hornbuckle KC: Inadvertent polychlorinated biphenyls in commercial paint pigments. Environ Sci Technol 2009, 44:2822-2827.
4. Rodenburg LA, Guo J, Du S, Cavallo GJ: Evidence for unique and ubiquitous environmental sources of 3,3′-dichlorobiphenyl (PCB 11). Environ Sci Technol 2010, 44:2816-2821.
5. Centers for Disease Control and Prevention (CDC): Fourth National Report on Human Exposure to Environmental Chemicals. Atlanta 2003.
6. World Health Organization: Polychlorinated Biphenyls and Terphenyls, Geneva , 2 1993, [Environmental Health Criteria, No. 140].
7. Kraugerud M, Zimmer KE, Dahl E, Berg V, Olsaker I, Farstad W, Ropstad E, Verhaegen S: Three structurally different polychlorinated biphenyl congeners (Pcb 118, 153, and 126) affect hormone production and gene expression in the human H295R in vitro model. J Toxicol Environ Health A 2010, 73:1122-1132.
8. Bonefeld-Jorgensen EC, Andersen HR, Rasmussen TH, Vinggaard AM: Effect of highly bioaccumulated polychlorinated biphenyl congeners on estrogen and androgen receptor activity. Toxicology 2001, 158:141-153. (Pubitemid 32244066)
9. Connor K, Ramamoorthy K, Moore M, Mustain M, Chen I, Safe S, Zacharewski T, Gillesby B, Joyeux A, Balaguer P: Hydroxylated polychlorinated biphenyls (PCBs) as estrogens and antiestrogens: structure-activity relationships. Toxicol Appl Pharmacol 1997, 145:111-123. (Pubitemid 27294776)
10. Portigal CL, Cowell SP, Fedoruk MN, Butler CM, Rennie PS, Nelson CC: Polychlorinated biphenyls interfere with androgen-induced transcriptional activation and hormone binding. Toxicol Appl Pharmacol 2002, 179:185-194. (Pubitemid 34275961)
11. Schrader TJ, Cooke GM: Effects of Aroclors and individual PCB congeners on activation of the human androgen receptor in vitro. Reprod Toxicol 2003, 17:15-23. (Pubitemid 36285758)
12. Hagmar L: Polychlorinated biphenyls and thyroid status in humans: a review. Thyroid 2003, 13:1021-1028.
13. Salay E, Garabrant D: Polychlorinated biphenyls and thyroid hormones in adults: a systematic review appraisal of epidemiological studies. Chemosphere 2009, 74:1413-1419.
14. Ma R, Sassoon DA: PCBs exert an estrogenic effect through repression of the Wnt7a signaling pathway in the female reproductive tract. Environ Health Perspect 2006, 114:898-904. (Pubitemid 43871740)
15. Toft G, Hagmar L, Giwercman A, Bonde JP: Epidemiological evidence on reproductive effects of persistent organochlorines in humans. Reprod Toxicol 2004, 19:5-26. (Pubitemid 39164873)
16. James WH: Hormonal control of sex ratio. J Theor Biol 1986, 118:427-441.
17. James WH: Further support for the hypothesis that parental hormone levels around the time of conception are associated with human sex ratios at birth. J Biosoc Sci 2008, 40:855-861.
18. James WH: Evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels around the time of conception. J Endocrinol 2008, 198:3-15.
19. Grech V, Vassallo-Agius P, Savona-Ventura C: Secular trends in sex ratios at birth in North America and Europe over the second half of the 20th century. J Epidemiol Community Health 2003, 57:612-615. (Pubitemid 36930289)
20. Garfinkel J, Selvin S: A multivariate analysis of the relationship between parental age and birth order and the human secondary sex ratio. J Biosoc Sci 1976, 8:113-121.
21. Ruder A: Paternal-age and birth-order effect on the human secondary sex ratio. Am J Hum Genet 1985, 37:362-372.
22. Teitelbaum MS, Mantel N, Stark CR: Limited dependence of the human sex ratio on birth order and parental ages. Am J Hum Genet 1971, 23:271-280.
23. Beratis NG, Asimacopoulou A, Varvarigou A: Association of secondary sex ratio with smoking and parity. Fertil Steril 2008, 89:662-667. (Pubitemid 351335021)
24. Erickson JD: The secondary sex ratio in the United States 1969-71: association with race, parental ages, birth order, paternal education and legitimacy. Ann Hum Genet 1976, 40:205-212.
25. Jacobsen R: Parental ages and the secondary sex ratio. Hum Reprod 2001, 16:2244.
26. James WH: The variations of human sex ratio at birth with time of conception within the cycle, coital rate around the time of conception, duration of time taken to achieve conception, and duration of gestation: a synthesis. J Theor Biol 2008, 255:199-204.
27. Kankova S, Kodym P, Frynta D, Vavrinova R, Kubena A, Flegr J: Influence of latent toxoplasmosis on the secondary sex ratio in mice. Parasitology 2007, 134:1709-1717. (Pubitemid 47530779)
28. Kankova S, Sulc J, Nouzova K, Fajfrlik K, Frynta D, Flegr J: Women infected with parasite Toxoplasma have more sons. Naturwissenschaften 2007, 94:122-127. (Pubitemid 46122167)
29. Chahnazarian A, Blumberg BS, London WT: Hepatitis B and the sex ratio at birth: a comparative analysis of four populations. J Biosoc Sci 1988, 20:357-370.
30. del Rio Gomez I, Marshall T, Tsai P, Shao YS, Guo YL: Number of boys born to men exposed to polychlorinated byphenyls. Lancet 2002, 360:143-144. (Pubitemid 34786207)
31. Yoshimura T, Kaneko S, Hayabuchi H: Sex ratio in offspring of those affected by dioxin and dioxin-like compounds: the Yusho, Seveso, and Yucheng incidents. Occup Environ Med 2001, 58:540-541. (Pubitemid 32675423)
32. Taylor KC, Jackson LW, Lynch CD, Kostyniak PJ, Buck Louis GM: Preconception maternal polychlorinated biphenyl concentrations and the secondary sex ratio. Environ Res 2007, 103:99-105. (Pubitemid 44920195)
33. Weisskopf MG, Anderson HA, Hanrahan LP: Decreased sex ratio following maternal exposure to polychlorinated biphenyls from contaminated Great Lakes sport-caught fish: a retrospective cohort study. Environ Health 2003, 2:2.
34. Hopf NB, Waters MA, Ruder AM: Cumulative exposure estimates for polychlorinated biphenyls using a job-exposure matrix. Chemosphere 2009, 76:185-193.
35. Brown DP, Jones M: Mortality and industrial hygiene study of workers exposed to polychlorinated biphenyls. Arch Environ Health 1981, 36:120-129. (Pubitemid 12250638)
36. Sinks T, Steele G, Smith AB, Watkins K, Shults RA: Mortality among workers exposed to polychlorinated biphenyls. Am J Epidemiol 1992, 136:389-398.
37. Smith AH, Fisher DO, Pearce N, Chapman CJ: Congenital defects and miscarriages among New Zealand 2, 4, 5-T sprayers. Arch Environ Health 1982, 37:197-200.
38. Brown DP: Mortality of workers exposed to polychlorinated biphenyls-an update. Arch Environ Health 1987, 42:333-339.
39. Prince MM, Hein MJ, Ruder AM, Waters MA, Laber PA, Whelan EA: Update: cohort mortality study of workers highly exposed to polychlorinated biphenyls (PCBs) during the manufacture of electrical capacitors, 1940-1998. Environ Health 2006, 5:13.
40. Prince MM, Ruder AM, Hein MJ, Waters MA, Whelan EA, Nilsen N, Ward EM, Schnorr TM, Laber PA, Davis-King KE: Mortality and exposure response among 14,458 electrical capacitor manufacturing workers exposed to polychlorinated biphenyls (PCBs). Environ Health Perspect 2006, 114:1508-1514. (Pubitemid 44509646)
41. Ruder AM, Hein MJ, Nilsen N, Waters MA, Laber P, Davis-King K, Prince MM, Whelan E: Mortality among workers exposed to polychlorinated biphenyls (PCBs) in an electrical capacitor manufacturing plant in Indiana: an update. Environ Health Perspect 2006, 114:18-23. (Pubitemid 43064784)
42. Steenland K, Hein MJ, Cassinelli RT, Prince MM, Nilsen NB, Whelan EA, Waters MA, Ruder AM, Schnorr TM: Polychlorinated biphenyls and neurodegenerative disease mortality in an occupational cohort. Epidemiology 2006, 17:8-13.
43. Silver SR, Whelan EA, Deddens JA, Steenland NK, Hopf NB, Waters MA, Ruder AM, Prince MM, Yong LC, Hein MJ, Ward EM: Occupational exposure to polychlorinated biphenyls and risk of breast cancer. Environ Health Perspect 2009, 117:276-282.
44. Nilsen NB, Waters MA, Prince MM, Zivkovich ZE, Ruder AM: Workers Exposed to PCBs in a Capacitor Manufacturing Plant (Plant 1; 1948-1977). Cincinnati 2004, [NIOSH: NY, Fort Edwards, Hudson Falls].
45. Nilsen NB, Waters MA, Prince MM, Zivkovich ZE, Ruder AM: Workers Exposed to PCBs in a Capacitor Manufacturing Plant (Plant 2; 1938-1977). Cincinnati 2004, [NIOSH: MA, New Bedford].
46. Hopf NB, Waters MA: Development of a retrospective job exposure matrix for PCB-exposed workers in capacitor manufacturing. J Occup Health 2010, 52(1):99-208.
47. Vatten LJ, Skjaerven R: Offspring sex and pregnancy outcome by length of gestation. Early Hum Dev 2004, 76:47-54. (Pubitemid 38058795)
48. Brettell R, Yeh PS, Impey LW: Examination of the association between male gender and preterm delivery. Eur J Obstet Gynecol Reprod Biol 2008, 141:123-126.
49. Verner MA, Charbonneau M, Lopez-Carrillo L, Haddad S: Physiologically based pharmacokinetic modeling of persistent organic pollutants for lifetime exposure assessment: a new tool in breast cancer epidemiologic studies. Environ Health Perspect 2008, 116:886-892. (Pubitemid 351943895)
50. Zeitlin J, Ancel PY, Larroque B, Kaminski M: Fetal sex and indicated very preterm birth: results of the EPIPAGE study. Am J Obstet Gynecol 2004, 190:1322-1325. (Pubitemid 38692215)
51. Kleinbaum DG, Kupper LL, Muller KE, Nizam A: Applied Regression Analysis and Other Multivariable Methods. 3 edition. Pacific Grove, CA: Duxbury Press - Brooks/Cole Publishing Co; 1998.
52. Terrell ML, Berzen AK, Small CM, Cameron LL, Wirth JJ, Marcus M: A cohort study of the association between secondary sex ratio and parental exposure to polybrominated biphenyl (PBB) and polychlorinated biphenyl (PCB). Environ Health 2009, 8:35.
53. Hertz-Picciotto I, Jusko TA, Willman EJ, Baker RJ, Keller JA, Teplin SW, Charles MJ: A cohort study of in utero polychlorinated biphenyl (PCB) exposures in relation to secondary sex ratio. Environ Health 2008, 7:37.
54. Wolff MS, Fischbein A, Selikoff IJ: Changes in PCB serum concentrations among capacitor manufacturing workers. Environ Res 1992, 59:202-216.
55. Smith AB, Schloemer J, Lowry LK, Smallwood AW, Ligo RN, Tanaka S, Stringer W, Jones M, Hervin R, Glueck CJ: Metabolic and health consequences of occupational exposure to polychlorinated biphenyls. Br J Ind Med 1982, 39:361-369. (Pubitemid 13245646)
56. Rogan WJ, Gladen BC, Guo YL, Hsu CC: Sex ratio after exposure to dioxin-like chemicals in Taiwan. Lancet 1999, 353:206-207. (Pubitemid 29088036)
57. Guo YL, Lambert GH, Hsu CC, Hsu MM: Yucheng: health effects of prenatal exposure to polychlorinated biphenyls and dibenzofurans. Int Arch Occup Environ Health 2004, 77:153-158. (Pubitemid 38678973)
58. Wise LA, Palmer JR, Hatch EE, Troisi R, Titus-Ernstoff L, Herbst AL, Kaufman R, Noller KL, Hoover RN: Secondary sex ratio among women exposed to diethylstilbestrol in utero. Environ Health Perspect 2007, 115:1314-1319. (Pubitemid 47471255)
59. Wise LA, Titus-Ernstoff L, Palmer JR, Hoover RN, Hatch EE, Perez KM, Strohsnitter WC, Kaufman R, Anderson D, Troisi R: Time to pregnancy and secondary sex ratio in men exposed prenatally to diethylstilbestrol. Am J Epidemiol 2007, 166:765-774. (Pubitemid 47428895)
60. Kodama H, Ota H: Transfer of polychlorinated biphenyls to infants from their mothers. Arch Environ Health 1980, 35:95-100. (Pubitemid 10102627)
61. Stewart PA, Carel R, Schairer C, Blair A: Comparison of industrial hygienists' exposure evaluations for an epidemiologic study. Scand J Work Environ Health 2000, 26:44-51. (Pubitemid 30122281)
62. Tiido T, Rignell-Hydbom A, Jonsson BA, Giwercman YL, Pedersen HS, Wojtyniak B, Ludwicki JK, Lesovoy V, Zvyezday V, Spano M, et al: Impact of PCB and p,p'-DDE contaminants on human sperm Y:X chromosome ratio: studies in three European populations and the Inuit population in Greenland. Environ Health Perspect 2006, 114:718-724.