Co-culture based blood-brain barrier in vitro model, a tissue engineering approach using immortalized cell lines for drug transport study

Applied Biochemistry and Biotechnology

Volumn 163, Issue 2, 2011, Pages 278-295

  Zhang, Zhiqi ^a   McGoron, Anthony J ^a   Crumpler, Eric T ^a   Li, Chen Zhong ^a  

^a Florida International University   (United States)

Author keywords

Blood brain barrier; Co culture; Drug delivery; In vitro; Membrane impedance; Occludin; Tight junction; Transport; Western blot

Indexed keywords

BLOOD-BRAIN BARRIER; CO-CULTURE; IN-VITRO; OCCLUDIN; TIGHT JUNCTIONS; TRANSPORT; WESTERN BLOTS;

BIOMIMETICS; BLOOD; DRUG DELIVERY; ENDOTHELIAL CELLS; FLUORESCENCE MICROSCOPY; LIVING SYSTEMS STUDIES; SELF ASSEMBLY; TISSUE ENGINEERING;

CELL CULTURE;

BIOMIMETIC MATERIAL; CALCEIN; DOXORUBICIN; OCCLUDIN; SULFORHODAMINE B;

ANIMAL CELL; ARTICLE; ASTROCYTE; BASEMENT MEMBRANE; BLOOD BRAIN BARRIER; CELL IMMORTALIZATION; CELL LINE; CELL LOSS; CELL STRUCTURE; COCULTURE; COLORIMETRY; CONTROLLED STUDY; DRUG TRANSPORT; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; IMMUNOFLUORESCENCE MICROSCOPY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; TIGHT JUNCTION; TISSUE ENGINEERING; TRANS ENDOTHELIAL ELECTRICAL RESISTANCE; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; CAFFEINE; CELL LINE; COCULTURE TECHNIQUES; ELECTRIC IMPEDANCE; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX; FLUORESCEINS; GENE EXPRESSION; MEMBRANE PROTEINS; MICE; MODELS, BIOLOGICAL; RATS; REPRODUCIBILITY OF RESULTS; TIGHT JUNCTIONS; TISSUE ENGINEERING;

EID: 79952697458     PISSN: 02732289     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12010-010-9037-6     Document Type: Article

References (37)

1. Zhang, Y., & Miller, D. W. (2005). Drug Delivery Principles and Applications. In B. Wang, T. Siahaan, & R. A. Soltero (Eds.), Hoboken. New Jersey: John Wiley & Sons, Inc.
2. Garcia-Garcia, E., Gil, S., Andrieux, K., Desmaele, D., Nicolas, V., Taran, F., et al. (2005). Cellular and Molecular Life Sciences, 62(12), 1400-1408.
3. Engelhardt, B. (2003). Cell and Tissue Research, 314(1), 119-129.
4. Hawkins, B. T., & Davis, T. P. (2005). Revelation, 57(2), 173-185.
5. Zlokovic, B. V. (2008). Neuron, 57(2), 178-201.
6. Pardridge, W. M. (1999). Journal of Neurovirology, 5(6), 556-569.
7. Rubin, L. L., & Staddon, J. M. (1999). Annual Review of Neuroscience, 22(1), 11-28.
8. Haseloff, R. F., Blasig, I. E., Bauer, H. C., & Bauer, H. (2008). BBA-Biomembranes., 1778(3), 588-600.
9. Kacem, K., Lacombe, P., Seylaz, J., & Bonvento, G. (1998). Glia, 23(1), 1-10.
10. Barrios-Rodiles, Brown, M. K. R., Ozdamar, B., Bose, R., Liu, Z., Donovan, R. S., et al. (2005). Science, 307(5715), 1621-1625.
11. Li, D., & Mrsny, R. J. (2000). The Journal of Cell Biology, 148(4), 791-800.
12. Yu, A. S. L., McCarthy, K. M., Francis, S. A., McCormack, J. M., Lai, J., Rogers, R. A., et al. (2005). American Journal of Physiology. Cell Physiology, 288(6), 1231-1241.
13. Murata, M., Kojima, T., Yamamoto, T., Go, M., Takano, K., Osanai, M., et al. (2005). Experimental Cell Research, 310(1), 140-151.
14. Osanai, M., Murata, M., Nishikiori, N., Chiba, H., Kojima, T., & Sawada, N. (2006). Cancer Research, 66(18), 9125-9133.
15. Wang, Z., Mandell, K. J., Parkos, C. A., Mrsny, R. J., & Nusrat, A. (2005). Oncogene, 24(27), 4412-4420.
16. Mizuguchi, H., Utoguchi, N., & Mayumi, T. (1997). Brain Research Protocols, 1(4), 339-343.
17. Abbott, N. J., Rönnbäck, L., & Hansson, E. (2006). Nature Reviews. Neuroscience, 7(1), 41-53.
18. Haring, H. P., Akamine, B. S., Habermann, R., Koziol, J. A., & Del Zoppo, G. J. (1996). Neuropath. Exp. Neur., 55(2), 236-245.
19. Milner, R., & Campbell, I. L. (2002). Molecular and Cellular Neurosciences, 20(4), 616-626.
20. Abbott, N. J. (2004). Drug. Discov. Today.: Technologies, 1(4), 407-416.
21. Garberg, P., Ball, M., Borg, N., Cecchelli, R., Fenart, L., Hurst, R. D., et al. (2005). Toxicol In Vitro, 19 (3), 299-334.
22. Yoo, J. W., Kim, Y. S., Lee, S. H., Lee, M. K., Roh, H. J., Jhun, B. H., et al. (2003). Pharmaceutical Research, 20(10), 1690-1696.
23. Li, C.-Z., Taniguchi, I., & Mulchandani, A. (2009). Bioelectrochemistry, 75, 182-188.
24. Gray, T. E., Guzman, K., Davis, C. W., Abdullah, L. H., & Nettesheim, P. (1996). Am. J. Resp. Cell. Mol., 14(1), 104-112.
25. Levashova, Z. B., Plisov, S. Y., & Perantoni, A. O. (2003). Kidney International, 63(6), 2075-2087.
26. Li, C.-Z., Nishiyama, K., Taniguchi, I. (2000). Electrochimica Acta, 45, 2883-2888.
27. Radany, E. H., Brenner, M., Besnard, F., Bigornia, V., Bishop, J. M., & Deschepper, C. F. (1992). P. Natl. Acad. Sci. USA, 89(14), 6467-6471.
28. Hurst, R. D., & Fritz, I. B. (1996). Journal of Cellular Physiology, 167(1), 81-88.
29. Vichai, V., & Kirtikara, K. (2006). Nature Protocols, 1(2), 1112-1116.
30. Flaten, G. E., Dhanikula, A. B., Luthman, K., & Brandl, M. (2006). European Journal of Pharmaceutical Sciences, 27(1), 80-90.
31. McCall, A. L., Millington, W. R., & Wurtman, R. J. (1982). Life Sciences, 31, 2709-2715.
32. Nakazono, T., Murakami, T., Sakai, S., Higashi, Y., & Yata, N. (1992). Chemical & Pharmaceutical Bulletin, 40, 2510-2515.
33. Sadzuka, Y., Hatakeyama, H., Daimon, T., & Sonobe, T. (2008). International Journal of Pharmaceutics, 354(1-2), 63-69.
34. Diglio, C. A., Grammas, P., Giacomelli, F., & Wiener, J. (1982). Laboratory Investigation, 46(6), 554-563.
35. Herrmann, J., Gressner, A. M., & Weiskirchen, R. (2007). Journal of Cellular and Molecular Medicine, 11(4), 704-722.
36. Kuchler-Bopp, S., Delaunoy, J. P., Artault, J. C., Zaepfel, M., & Dietrich, J. B. (1999). NeuroReport, 10 (6), 1347-1353.
37. Hurst, R. D., Heales, S. J. R., Dobbie, M. S., Barker, J. E., & Clark, J. B. (1998). Brain Research, 802(1-2), 232-240.