Novel diagnostics: Progress toward a breath test for invasive Aspergillus fumigatus

Medical Mycology

Volumn 49, Issue SUPPL. 1, 2011, Pages

  Chambers, Stephen T ^a   Bhandari, Shrawan ^a   Scott Thomas, Amy ^a   Syhre, Mona ^b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

2 Pentylfuran; Aspergillus fumigatus; breath test; mass spectrometry

Indexed keywords

AMPHOTERICIN B LIPID COMPLEX; CARBOPLATIN; CREATININE; ETOPOSIDE; ITRACONAZOLE; POSACONAZOLE; VOLATILE ORGANIC COMPOUND; VORICONAZOLE;

ADULT; AGED; ASPERGILLUS FUMIGATUS; ASPIRATION BIOPSY; BREATH ANALYSIS; CANCER CHEMOTHERAPY; CASE REPORT; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPUTER ASSISTED TOMOGRAPHY; CONFERENCE PAPER; CONGESTIVE HEART FAILURE; COUGHING; CREATININE BLOOD LEVEL; CUNNINGHAMELLA; CYTOLOGY; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG FEVER; DYSPNEA; EXCISION; FEVER; FOLLOW UP; FORCED EXPIRATION; FUNGAL COLONIZATION; FUNGUS HYPHAE; FUNGUS ISOLATION; GASTROINTESTINAL ABSORPTION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPERTENSION; INVASIVE ASPERGILLOSIS; ION MOBILITY SPECTROMETRY; ISCHEMIC HEART DISEASE; KIDNEY DISEASE; LIPID DIET; LUNG ASPERGILLOSIS; LUNG BIOPSY; LUNG LESION; LUNG SMALL CELL CANCER; MALE; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; MEDICAL HISTORY; NECK DISSECTION; NEUTROPENIA; NONHUMAN; PLEURA FLUID; RIGOR; SELECTED ION FLOW TUBE MASS SPECTROMETRY; SMOKING; SPUTUM CULTURE; SQUAMOUS CELL CARCINOMA; STREPTOCOCCUS PNEUMONIAE; SWEAT; THORAX PAIN; TREATMENT RESPONSE; TUMOR VOLUME;

ADULT; AGED, 80 AND OVER; ASPERGILLUS FUMIGATUS; BREATH TESTS; FURANS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; INVASIVE PULMONARY ASPERGILLOSIS; MALE; RESPIRATORY TRACT INFECTIONS; VOLATILE ORGANIC COMPOUNDS;

ASPERGILLUS; ASPERGILLUS FUMIGATUS; BACTERIA (MICROORGANISMS); MAMMALIA; STREPTOCOCCUS PNEUMONIAE;

EID: 79952682326     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.3109/13693786.2010.508187     Document Type: Conference Paper

References (37)

1. Smith AD, Cowan JO, Brassett KP, Herbison GP, Taylor DR. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med 2005; 352: 2163-2173.
2. Cox CD, Parker J. Use of 2-aminoacetophenone production in iden-tification of Pseudomonas aeruginosa. J Clin Microbiol 1979; 9: 479-484. (Pubitemid 9157629)
3. Weetjens BJ, Mgode GF, Machang'u RS, et al. African pouched rats for the detection of pulmonary tuberculosis in sputum samples. Int J Tuberc Lung Dis 2009; 13: 737-743.
4. Willis CM, Church SM, Guest CM, et al. Olfactory detection of human bladder cancer by dogs: proof of principle study. BMJ 2004; 329: 712-715.
5. Phillips M, Herrera J, Krishnan S, et al. Variation in volatile organic compounds in the breath of normal humans. J Chromatogr B 1999; 729: 75-88. (Pubitemid 29264111)
6. Peris M, Escuder-Gilabert L. A 21st century technique for food control: electronic noses. Analytica Chimica Acta 2009; 638: 1-15.
7. Turner APF, Magan N. Electronic noses and disease diagnostics. Nat Rev Micro 2004; 2: 161-166.
8. Persaud K, Dodd G. Analysis of discrimination mechanisms in the mammalian olfactory system using a model nose. Nature 1982; 299: 352-355. (Pubitemid 12012862)
9. Scott SM, James D, Ali Z. Data analysis for electronic nose systems. Microchimica Acta 2006; 156: 183-207.
10. Scott SM, James D, Ali Z, O'Hare WT, Rowell FJ. Total luminescence spectroscopy with pattern recognition for classification of edible oils. Analyst 2003; 128: 966-973. (Pubitemid 36897892)
11. Berna AZ, Anderson AR, Trowell SC. Bio-benchmarking of electronic nose sensors. PLoS One 2009; 4: e6406.
12. Preti G, Thaler E, Hanson CW, et al. Volatile compounds characteristic of sinus-related bacteria and infected sinus mucus: analysis by solid-phase microextraction and gas chromatography-mass spectrom-etry. J Chromatogr B 2009; 877: 2011-2018.
13. Ligor M, Ligor T, Bajtarevic A, et al. Determination of volatile organic compounds in exhaled breath of patients with lung cancer using solid phase microextraction and gas chromatography mass spectrom-etry. Clin Chem Lab Med 2009; 47: 550-560.
14. Westhoff M, Litterst P, Freitag L, et al. Ion mobility spectrometry for the detection of volatile organic compounds in exhaled breath of patients with lung cancer: results of a pilot study. Thorax 2009; 64: 744-748.
15. Ruzsanyi V, Baumbach JI, Sielemann S, et al. Detection of human metabolites using multi-capillary columns coupled to ion mobility spectrometers. J ChromatogrA 2005; 1084: 145-151. (Pubitemid 40966921)
16. Scotter JM, Langford VS, Wilson PF, McEwan MJ, Chambers ST. Real-time detection of common microbial volatile organic compounds from medically important fungi by Selected Ion Flow Tube-Mass Spectrometry (SIFT-MS). J Microbiol Methods 2005; 63: 127-134. (Pubitemid 41443321)
17. Chambers ST, Syhre M, Murdoch DR, McCartin F, Epton MJ. Detection of 2-pentylfuran in the breath of patients with Aspergillus fumigatus. Med Mycol 2009; 47: 468-476.
18. Syhre M, Scotter JM, Chambers ST. Investigation into the production of 2-Pentylfuran by Aspergillus fumigatus and other respiratory pathogens in vitro and human breath samples. Med Mycol 2007; 46: 209-215.
19. Syhre M, Manning L, Phuanukoonnon S, Harino P, Chambers ST. The scent of Mycobacterium tuberculosis-Part II breath. Tuberculosis (Edinb) 2009; 89: 263-266.
20. Syhre M, Chambers ST. The scent of Mycobacterium tuberculosis. Tuberculosis (Edinb.) 2008; 88: 317-323.
21. Gao P, Korley F, Martin J, Chen BT. Determination of unique microbial volatile organic compounds produced by f ve Aspergillus species commonly found in problem buildings. AIHA J 2002; 63: 135-140.
22. Feussner I, Wasternack C. The lipoxygenase pathway. Annu Rev Plant Biol 2002; 53: 275-297. (Pubitemid 36257496)
23. Brash AR. Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate. J Biol Chem 1999; 274: 23679-23682.
24. St. Angelo A, Legendre M, Dupuy H. Identification of lipoxygenase- linoleate decomposition products by direct gas chromatography-mass spectrometry. Lipids 1980; 15: 45-49.
25. Boue SM, Shih BY, Carter-Wientjes CH, Cleveland TE. Effect of soybean lipoxygenase on volatile generation and inhibition of Aspergillus f avus mycelial growth. J Agric Food Chem 2005; 53: 4778-4783. (Pubitemid 40937597)
26. Yuan SH, Chang SKC. Selected odor compounds in cooked soymilk as affected by soybean materials and direct steam injection. J Food Sci 2007; 72: S481-S486. (Pubitemid 47373541)
27. Spiteller D, Spiteller G. Identification of toxic 2,4-decadienal in oxidized, low-density lipoprotein by solid-phase microextraction. Angew Chem Int Ed Engl 2000; 39: 583-585. (Pubitemid 30101749)
28. Min DB, Boff JM. Chemistry and reaction of singlet oxygen in foods. Compr Rev Food Sci F 2002; 1: 58-72.
29. Min DB, Callison AL, Lee HO. Singlet oxygen oxidation for 2-pentylfuran and 2-pentenyfuran formation in soybean oil. J Food Sci 2003; 68: 1175-1178. (Pubitemid 36632052)
30. Nierman WC, Pain A, Anderson MJ, et al. Genomic sequence of the pathogenic and allergenic f lamentous fungus Aspergillus fumigatus. Nature 2005; 438: 1151-1156. (Pubitemid 41831684)
31. Lutteke T, Krieg P, Furstenberger G, von der Lieth CW. LOX-DB-a database on lipoxygenases. Bioinformatics 2003; 19: 2482-2483.
32. Dudda A, Spiteller G, Kobelt F. Lipid oxidation products in ischemic porcine heart tissue. Chem Phys Lipids 1996; 82: 39-51. (Pubitemid 26312859)
33. Chida M, Sone Y, Tamura H. Aroma characteristics of stored tobacco cut leaves analyzed by a high vacuum distillation and canister system. J Agric Food Chem 2004; 52: 7918-7924. (Pubitemid 40053675)
34. Krist S, Stuebiger G, Unterweger H, Bandion F, Buchbauer G. Analysis of volatile compounds and triglycerides of seed oils extracted from different poppy varieties ( Papaver somniferum L.). J Agric Food Chem 2005; 53: 8310-8316. (Pubitemid 41564643)
35. Yang DS, Lee K-S, Jeong OY, Kim K-J, Kays SJ. Characterization of volatile aroma compounds in cooked black rice. J Agric Food Chem 2007; 56: 235-240.
36. Kalua CM, Bedgood DR, Bishop AG, Prenzler PD. Changes in virgin olive oil quality during low-temperature fruit storage. J Agric Food Chem 2008; 56: 2415-2422. (Pubitemid 351570434)
37. Ranau R, Kleeberg KK, Schlegelmilch M, et al. Analytical determination of the suitability of different processes for the treatment of odorous waste gas. Waste Management 2005; 25: 908-916. (Pubitemid 41323816)